#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11135	uniprotkb:P87506	intact:EBI-8111464|intact:MINT-232909|uniprotkb:Q0A2G5|psi-mi:MINT-5229187	intact:EBI-8111443|intact:MINT-232920	psi-mi:hema_i83a4(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short)	psi-mi:hema_i87a1(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Ha et al. (2002)	pubmed:11867515|mint:MINT-5215143	taxid:380285(i83a4)|taxid:380285("Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)")	taxid:293055(i87a1)|taxid:293055("Influenza A virus (strain A/Mallard/Ohio/556/1987 H5N9)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8111478|mint:MINT-25009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|mint:MINT-712049(identity)	interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|mint:MINT-712056(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore|comment:"Stoichiometry: 1.0"	comment:In the xray complex 1jsm, P11135 is chain A and P87506 is chain B Resolution 1.900|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:/YCBCKh/yTV4bcDR0YCev2ed+DA380285	rogid:RY2kPqY/dNFyOxi0zjDOv9V1mao293055	intact-crc:6553A5BDC788005D|rigid:hTqQNuhExyOf3GhaHDxlJT//u14	false	tag:?-?(MINT-712050)	tag:?-?(MINT-712057)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)