#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P45975	uniprotkb:Q94517	intact:EBI-110378|uniprotkb:Q9VFA6|intact:EBI-3406895	intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173	psi-mi:suv39_drome(display_long)|uniprotkb:KMT1(gene name synonym)|uniprotkb:Protein suppressor of variegation 3-9(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:"Su(var)3-9"(gene name)|psi-mi:"Su(var)3-9"(display_short)|uniprotkb:CG6476(orf name)	psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name)	psi-mi:"MI:0019"(coimmunoprecipitation)	Czermin et al. (2001)	pubmed:11571273|mint:MINT-5214571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-302219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524357.2|flybase:FBgn0263755|dip:DIP-23970N|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016570"(histone modification)|go:"GO:0016571"(histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR027417	ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N	-	-	-	comment:"Su(var)3-9 was myc tagged."|caution:Interaction not observed in in vitro GST pull down assay.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2004/03/31	2014/10/16	rogid:sZQH9rg/9J1bwqpUi3Y+VJE1N9A7227	rogid:HYHCai8wP8lueOr33vYY32w2pHU7227	intact-crc:D332DC983D0C51E5|rigid:FPLbPFbAB2rEJZyDvt1FgUML7o8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q94517	uniprotkb:P45975	intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173	intact:EBI-110378|uniprotkb:Q9VFA6|intact:EBI-3406895	psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name)	psi-mi:suv39_drome(display_long)|uniprotkb:KMT1(gene name synonym)|uniprotkb:Protein suppressor of variegation 3-9(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:"Su(var)3-9"(gene name)|psi-mi:"Su(var)3-9"(display_short)|uniprotkb:CG6476(orf name)	psi-mi:"MI:0019"(coimmunoprecipitation)	Czermin et al. (2001)	pubmed:11571273|mint:MINT-5214571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-302224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N	refseq:NP_524357.2|flybase:FBgn0263755|dip:DIP-23970N|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016570"(histone modification)|go:"GO:0016571"(histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR027417	-	-	-	comment:RPD3 was FLAG tagged.|caution:Interaction not observed in in vitro GST pull down assay.|resulting-ptm:Mehtylation of H3 observed.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2004/03/31	2014/10/16	rogid:HYHCai8wP8lueOr33vYY32w2pHU7227	rogid:sZQH9rg/9J1bwqpUi3Y+VJE1N9A7227	intact-crc:0DA930865A70629C|rigid:FPLbPFbAB2rEJZyDvt1FgUML7o8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)