#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27633 uniprotkb:Q01658 intact:EBI-7906467|intact:MINT-204859|uniprotkb:Q3KPN3 intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295 psi-mi:tbp_xenla(display_long)|uniprotkb:tbp(gene name)|psi-mi:tbp(display_short)|uniprotkb:tfiid(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Kamada et al. (2001) pubmed:11461703|mint:MINT-5214285 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7906488|mint:MINT-25096 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030491|interpro:IPR033710|refseq:NP_001084369.1|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR000814(TATA-box binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003677"(DNA binding)|mint:MINT-581097(identity) refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847|mint:MINT-581090(identity) - function:"General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II"|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1jfi, Q01658 is chain B and P27633 is chain C Resolution 2.620|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:ICmlMWq9H6HjjsfZcAsghahYc3U8355 rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606 intact-crc:B33E1FEC5C4897FA|rigid:IlQevqmWl3da3TcD2l7PVDJh0jQ false tag:?-?(MINT-581098) tag:?-?(MINT-581091) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)