#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9VEZ5	uniprotkb:Q9GYV5	intact:EBI-148871|uniprotkb:Q9GYV6|uniprotkb:Q9NJI1|uniprotkb:Q9U698|uniprotkb:Q9U7F5|ensemblmetazoa:FBpp0293344	intact:EBI-113108|uniprotkb:Q9W105|intact:EBI-2890361|ensemblmetazoa:FBpp0072333	psi-mi:ikkb_drome(display_long)|uniprotkb:IKKbeta(gene name)|psi-mi:IKKbeta(display_short)|uniprotkb:Cactus kinase IKK(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:IKK-like protein(gene name synonym)|uniprotkb:Immune response deficient protein 5(gene name synonym)|uniprotkb:Lipopolysaccharide-activated kinase(gene name synonym)|uniprotkb:ird5(gene name synonym)|uniprotkb:CG4201(orf name)	psi-mi:nemo_drome(display_long)|uniprotkb:key(gene name)|psi-mi:key(display_short)|uniprotkb:IKKGAMMA(gene name synonym)|uniprotkb:CG16910(orf name)|uniprotkb:Inhibitor of nuclear factor kappa B kinase subunit gamma(gene name synonym)|uniprotkb:NEMO homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Silverman et al. (2000)	pubmed:11018014	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-366817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0024222|refseq:NP_524751.3|ensemblmetazoa:FBgn0024222(gene)|ensemblmetazoa:FBtr0304804(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-198323|reactome:R-DME-209447|reactome:R-DME-214399|reactome:R-DME-5607761|reactome:R-DME-5676590|reactome:R-DME-9020702|dip:DIP-31307N	refseq:NP_523856.2|flybase:FBgn0041205|ensemblmetazoa:FBgn0041205(gene)|ensemblmetazoa:FBtr0072428(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR032419|interpro:IPR034735|reactome:R-DME-209447|reactome:R-DME-214399	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/06/08	2014/10/16	rogid:iXam5xaVfASMnNR7+YkTEGQNXHg7227	rogid:AkSyKL/nSfLZJRIM/2pcxppu6/c7227	intact-crc:B952C985F0FA74D9|rigid:+eFkmIybt6Eu0bHDoUnbks7zE3E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9GYV5	uniprotkb:Q9VEZ5	intact:EBI-113108|uniprotkb:Q9W105|intact:EBI-2890361|ensemblmetazoa:FBpp0072333	intact:EBI-148871|uniprotkb:Q9GYV6|uniprotkb:Q9NJI1|uniprotkb:Q9U698|uniprotkb:Q9U7F5|ensemblmetazoa:FBpp0293344	psi-mi:nemo_drome(display_long)|uniprotkb:key(gene name)|psi-mi:key(display_short)|uniprotkb:IKKGAMMA(gene name synonym)|uniprotkb:CG16910(orf name)|uniprotkb:Inhibitor of nuclear factor kappa B kinase subunit gamma(gene name synonym)|uniprotkb:NEMO homolog(gene name synonym)	psi-mi:ikkb_drome(display_long)|uniprotkb:IKKbeta(gene name)|psi-mi:IKKbeta(display_short)|uniprotkb:Cactus kinase IKK(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:IKK-like protein(gene name synonym)|uniprotkb:Immune response deficient protein 5(gene name synonym)|uniprotkb:Lipopolysaccharide-activated kinase(gene name synonym)|uniprotkb:ird5(gene name synonym)|uniprotkb:CG4201(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Silverman et al. (2000)	pubmed:11018014	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-366825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523856.2|flybase:FBgn0041205|ensemblmetazoa:FBgn0041205(gene)|ensemblmetazoa:FBtr0072428(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR032419|interpro:IPR034735|reactome:R-DME-209447|reactome:R-DME-214399	flybase:FBgn0024222|refseq:NP_524751.3|ensemblmetazoa:FBgn0024222(gene)|ensemblmetazoa:FBtr0304804(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-198323|reactome:R-DME-209447|reactome:R-DME-214399|reactome:R-DME-5607761|reactome:R-DME-5676590|reactome:R-DME-9020702|dip:DIP-31307N	-	-	-	comment:Key is FLAG tagged.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/06/08	2014/10/16	rogid:AkSyKL/nSfLZJRIM/2pcxppu6/c7227	rogid:iXam5xaVfASMnNR7+YkTEGQNXHg7227	intact-crc:87D41913B074620B|rigid:+eFkmIybt6Eu0bHDoUnbks7zE3E	false	flag tag:?-?	radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9VEZ5	uniprotkb:Q9GYV5	intact:EBI-148871|uniprotkb:Q9GYV6|uniprotkb:Q9NJI1|uniprotkb:Q9U698|uniprotkb:Q9U7F5|ensemblmetazoa:FBpp0293344	intact:EBI-113108|uniprotkb:Q9W105|intact:EBI-2890361|ensemblmetazoa:FBpp0072333	psi-mi:ikkb_drome(display_long)|uniprotkb:IKKbeta(gene name)|psi-mi:IKKbeta(display_short)|uniprotkb:Cactus kinase IKK(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:IKK-like protein(gene name synonym)|uniprotkb:Immune response deficient protein 5(gene name synonym)|uniprotkb:Lipopolysaccharide-activated kinase(gene name synonym)|uniprotkb:ird5(gene name synonym)|uniprotkb:CG4201(orf name)	psi-mi:nemo_drome(display_long)|uniprotkb:key(gene name)|psi-mi:key(display_short)|uniprotkb:IKKGAMMA(gene name synonym)|uniprotkb:CG16910(orf name)|uniprotkb:Inhibitor of nuclear factor kappa B kinase subunit gamma(gene name synonym)|uniprotkb:NEMO homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Silverman et al. (2000)	pubmed:11018014	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-366832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0024222|refseq:NP_524751.3|ensemblmetazoa:FBgn0024222(gene)|ensemblmetazoa:FBtr0304804(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-198323|reactome:R-DME-209447|reactome:R-DME-214399|reactome:R-DME-5607761|reactome:R-DME-5676590|reactome:R-DME-9020702|dip:DIP-31307N	refseq:NP_523856.2|flybase:FBgn0041205|ensemblmetazoa:FBgn0041205(gene)|ensemblmetazoa:FBtr0072428(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR032419|interpro:IPR034735|reactome:R-DME-209447|reactome:R-DME-214399	-	-	-	comment:Key is FLAG tagged.	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2004/06/08	2014/10/16	rogid:iXam5xaVfASMnNR7+YkTEGQNXHg7227	rogid:AkSyKL/nSfLZJRIM/2pcxppu6/c7227	intact-crc:B46629AE6BCE7E73|rigid:+eFkmIybt6Eu0bHDoUnbks7zE3E	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)