#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q62829 uniprotkb:Q90694 intact:EBI-7243644|intact:MINT-126419|ensembl:ENSRNOP00000006459|ensembl:ENSRNOP00000075221 intact:EBI-7243581|intact:MINT-126406|ensembl:ENSGALP00000034254|ensembl:ENSGALP00000050376 psi-mi:pak3_rat(display_long)|uniprotkb:Pak3(gene name)|psi-mi:Pak3(display_short)|uniprotkb:p21-activated kinase 3(gene name synonym)|uniprotkb:Beta-PAK(gene name synonym)|uniprotkb:p65-PAK(gene name synonym) psi-mi:cdc42_chick(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Gizachew et al. (2000) pubmed:10747784|mint:MINT-5212392 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7243673|mint:MINT-24845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006257401.1|refseq:NP_062083.1|rgd:3251|ensembl:ENSRNOG00000004676(gene)|ensembl:ENSRNOT00000006459(transcript)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035063|interpro:IPR036936|reactome:R-RNO-202433|reactome:R-RNO-389359|reactome:R-RNO-3928664|reactome:R-RNO-399954|reactome:R-RNO-5218920|reactome:R-RNO-5621575|reactome:R-RNO-5627123|reactome:R-RNO-5687128|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013420|ensembl:ENSRNOT00000089141(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|mint:MINT-414527(identity) refseq:XP_015152311.1|refseq:XP_015152312.1|refseq:NP_990379.1|ensembl:ENSGALG00000004796(gene)|ensembl:ENSGALT00000034897(transcript)|ensembl:ENSGALT00000049495(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030496"(midbody)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099563"(modification of synaptic structure)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-GGA-114604|reactome:R-GGA-182971|reactome:R-GGA-2029482|reactome:R-GGA-389359|reactome:R-GGA-3928662|reactome:R-GGA-4420097|reactome:R-GGA-525793|reactome:R-GGA-5625970|reactome:R-GGA-5626467|reactome:R-GGA-5627123|reactome:R-GGA-5663213|reactome:R-GGA-5663220|reactome:R-GGA-5687128|reactome:R-GGA-8964616|reactome:R-GGA-9013148|reactome:R-GGA-9013149|reactome:R-GGA-9013404|reactome:R-GGA-9013406|reactome:R-GGA-9013408|reactome:R-GGA-9013420|reactome:R-GGA-9013423|reactome:R-GGA-9013424|reactome:R-GGA-983231|go:"GO:0031274"(positive regulation of pseudopodium assembly)|mint:MINT-414520(identity) - comment:mint|function:Key regulator of synapse formation and plasticity in the hippocampus|comment:"Stoichiometry: 1.0" comment:mint|function:Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Causes the formation of thin, actin-rich surface projections called filopodia|comment:"Stoichiometry: 1.0" comment:In the xray complex 1ees, Q90694 is chain A and Q62829 is chain B Resolution|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:rULTVIWzqAAp9+9R+KEUd5eh9pg10116 rogid:dndpmAhg9JhhH84e0/CIWMa6EBk9031 intact-crc:EDF5A10807DC8952|rigid:/JwFh+nEz19OFeYfG/83oGDDOos false tag:?-?(MINT-414528) tag:?-?(MINT-414521) - - psi-mi:"MI:0093"(protein sequence identification) psi-mi:"MI:0093"(protein sequence identification)