#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53236 uniprotkb:Q06488 intact:EBI-16192|uniprotkb:Q45U30|ensemblfungi:YGR056W|uniprotkb:D6VUJ1 intact:EBI-16198|ensemblfungi:YLR357W|uniprotkb:D6VYZ5 psi-mi:rsc1_yeast(display_long)|uniprotkb:RSC1(gene name)|psi-mi:RSC1(display_short)|uniprotkb:RSC complex subunit RSC1(gene name synonym)|uniprotkb:YGR056W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 1(gene name synonym) psi-mi:rsc2_yeast(display_long)|uniprotkb:RSC2(gene name)|psi-mi:RSC2(display_short)|uniprotkb:RSC complex subunit RSC2(gene name synonym)|uniprotkb:L9638.1(orf name)|uniprotkb:YLR357W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 2(gene name synonym) psi-mi:"MI:0401"(biochemical) Cairns et al. (1999) pubmed:10619019 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74056 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR056W(gene)|ensemblfungi:YGR056W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR035700|interpro:IPR036427|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|interpro:IPR037382|interpro:IPR043151|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042173"(regulation of sporulation resulting in formation of a cellular spore)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|refseq:NP_011570.1|sgd:S000003288|dip:DIP-984N|mint:P53236 ensemblfungi:YLR357W(gene)|ensemblfungi:YLR357W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003682"(chromatin binding)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016586"(RSC-type complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR037382|interpro:IPR043151|rcsb pdb:4BB7|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|go:"GO:0042173"(regulation of sporulation resulting in formation of a cellular spore)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR035700|interpro:IPR036427|refseq:NP_013461.1|sgd:S000004349|dip:DIP-863N|mint:Q06488 pubmed:8980231(see-also) - crc64:7867866FD973F188 dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/10/24 2014/10/16 rogid:VG826fndhm2Eqr/1WgSQuaZbNec559292 rogid:m8jAmTXXCyoUnJPmorW0A7/o2js559292 intact-crc:04191EE7C6FC5A02|rigid:m4w1TAst6Tye/HeSl7t+J+jqdVU false - - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P53236 uniprotkb:P32597 intact:EBI-16192|uniprotkb:Q45U30|ensemblfungi:YGR056W|uniprotkb:D6VUJ1 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:rsc1_yeast(display_long)|uniprotkb:RSC1(gene name)|psi-mi:RSC1(display_short)|uniprotkb:RSC complex subunit RSC1(gene name synonym)|uniprotkb:YGR056W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 1(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cairns et al. (1999) pubmed:10619019 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR056W(gene)|ensemblfungi:YGR056W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR035700|interpro:IPR036427|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|interpro:IPR037382|interpro:IPR043151|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042173"(regulation of sporulation resulting in formation of a cellular spore)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|refseq:NP_011570.1|sgd:S000003288|dip:DIP-984N|mint:P53236 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - - crc64:269A91BD853C20D0 comment:Deletion of the C-terminal amino acids L496-L911 abolishes this interaction.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/10/24 2014/10/16 rogid:VG826fndhm2Eqr/1WgSQuaZbNec559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:F4E955D9CA6DCF4C|rigid:iDhuzVvcNNPHG/KYTDZagKZq8dk false binding-associated region:496-911|myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06488 uniprotkb:P32597 intact:EBI-16198|ensemblfungi:YLR357W|uniprotkb:D6VYZ5 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:rsc2_yeast(display_long)|uniprotkb:RSC2(gene name)|psi-mi:RSC2(display_short)|uniprotkb:RSC complex subunit RSC2(gene name synonym)|uniprotkb:L9638.1(orf name)|uniprotkb:YLR357W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 2(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cairns et al. (1999) pubmed:10619019 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR357W(gene)|ensemblfungi:YLR357W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003682"(chromatin binding)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016586"(RSC-type complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR037382|interpro:IPR043151|rcsb pdb:4BB7|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|go:"GO:0042173"(regulation of sporulation resulting in formation of a cellular spore)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR035700|interpro:IPR036427|refseq:NP_013461.1|sgd:S000004349|dip:DIP-863N|mint:Q06488 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:7867866FD973F188 crc64:269A91BD853C20D0 comment:Deletion of the C-terminal amino acids P580-S889 abolishes this interaction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/10/24 2014/10/16 rogid:m8jAmTXXCyoUnJPmorW0A7/o2js559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:8F880225952FA22C|rigid:R0nON0OBZtqRncHDGg8F5VyKtk0 false ha tag:?-?|binding-associated region:580-889 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)