#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P46684	uniprotkb:P08151	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-307765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:ZIC1 was HA-tagged and GLI1 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	intact-crc:02FDD9DA49A2A433|rigid:XrQD3d5SFm9AjsaJ32nP8ufj78k	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P46684	uniprotkb:Q8K0K3	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308039	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:q8k0k3_mouse(display_long)|uniprotkb:Gli2(gene name)|psi-mi:Gli2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR043359	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:ZIC1 was HA-tagged and GLI2 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:SBIGVb7VJHPoJbSpVgKbaLYL5FA10090	intact-crc:41FA90591B3BBB16|rigid:6WgekpBnAxPDG12YH/q6YrUu2iQ	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P46684	uniprotkb:P10071	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:ZIC1 was HA-tagged and GLI3 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	intact-crc:D7335F921A5A7FA0|rigid:7UuuMlDU0iwxtRF7Sk7Ol7DHMqs	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q62520	uniprotkb:P08151	intact:EBI-308076	intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8	psi-mi:zic2_mouse(display_long)|uniprotkb:Zic2(gene name)|psi-mi:Zic2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym)	psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643	refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:ZIC2 was HA-tagged and GLI1 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:wwSPtlbx7Gsi3R4AgFSa8uRY8B410090	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	intact-crc:A3265897529F438B|rigid:C3HWWkAQdKjZyT2RJMhyGrPZN0w	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q62520	uniprotkb:Q8K0K3	intact:EBI-308076	intact:EBI-308039	psi-mi:zic2_mouse(display_long)|uniprotkb:Zic2(gene name)|psi-mi:Zic2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym)	psi-mi:q8k0k3_mouse(display_long)|uniprotkb:Gli2(gene name)|psi-mi:Gli2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR043359	go:"GO:0005634"(nucleus)|go:"GO:0008589"(regulation of smoothened signaling pathway)	-	-	comment:ZIC2 was HA-tagged and GLI2 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:wwSPtlbx7Gsi3R4AgFSa8uRY8B410090	rogid:SBIGVb7VJHPoJbSpVgKbaLYL5FA10090	intact-crc:EFD9A82B0FE669DB|rigid:h1Fb1IAA0SOfTGXT4OJZ71Ar7xM	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P10071	uniprotkb:Q62520	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	intact:EBI-308076	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:zic2_mouse(display_long)|uniprotkb:Zic2(gene name)|psi-mi:Zic2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:ZIC2 was HA-tagged and GLI3 was Flag-tagged.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/03/29	2014/10/16	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	rogid:wwSPtlbx7Gsi3R4AgFSa8uRY8B410090	intact-crc:76E8DEDF01679818|rigid:9H4sQkNj3dSui5djYZlXSF3O4oA	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P46684	uniprotkb:P10071	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0005634"(nucleus)	-	-	comment:GLI3 was GST tagged and ZIC1 was Flag tagged. AA 300-384 of ZIC1 and AA 547-639 of GLI3 are sufficient for this interaction.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	intact-crc:1E26494596B51B7F|rigid:7UuuMlDU0iwxtRF7Sk7Ol7DHMqs	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q62520	uniprotkb:P10071	intact:EBI-308076	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	psi-mi:zic2_mouse(display_long)|uniprotkb:Zic2(gene name)|psi-mi:Zic2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym)	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	go:"GO:0005634"(nucleus)|go:"GO:0008589"(regulation of smoothened signaling pathway)	-	-	comment:GLI3 was GST tagged and ZIC2 was Flag tagged. AA 547-639 of GLI3 is sufficient for its interaction with ZIC2.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/03/29	2014/10/16	rogid:wwSPtlbx7Gsi3R4AgFSa8uRY8B410090	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	intact-crc:E77FEF534BBDB001|rigid:9H4sQkNj3dSui5djYZlXSF3O4oA	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q62521	uniprotkb:P10071	intact:EBI-308132|uniprotkb:Q3UYV1|ensembl:ENSMUSP00000085999|uniprotkb:A2AWK3|uniprotkb:Q8BSB3	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	psi-mi:zic3_mouse(display_long)|uniprotkb:Zic3(gene name)|psi-mi:Zic3(display_short)|uniprotkb:Zinc finger protein of the cerebellum 3(gene name synonym)	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033601.2|ensembl:ENSMUSG00000067860(gene)|ensembl:ENSMUST00000088627(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0035545"(determination of left/right asymmetry in nervous system)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|mint:Q62521	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	go:"GO:0005634"(nucleus)|go:"GO:0008589"(regulation of smoothened signaling pathway)	-	-	comment:GLI3 was GST tagged and ZIC3 was Flag tagged. AA 547-639 of GLI3 is sufficient for its interaction with ZIC3.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/03/29	2014/10/16	rogid:ooPtJpjY1temgbD2pSXjFvKoI3410090	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	intact-crc:CDFAD193D443712F|rigid:pScQEBmpM4nvzupeyLzlHplaqpA	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P46684	uniprotkb:P08151	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N	go:"GO:0005634"(nucleus)|go:"GO:0008589"(regulation of smoothened signaling pathway)	-	-	comment:ZIC1 was GST tagged and GLI1 was Flag tagged. AA 300-384 of ZIC1 is sufficient for its interaction with GLI1.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	intact-crc:3B678738D3202701|rigid:XrQD3d5SFm9AjsaJ32nP8ufj78k	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P46684	uniprotkb:Q8K0K3	intact:EBI-308006|uniprotkb:Q6PAK5|uniprotkb:Q80Y18|ensembl:ENSMUSP00000034927|ensembl:ENSMUSP00000068858	intact:EBI-308039	psi-mi:zic1_mouse(display_long)|uniprotkb:Zic1(gene name)|psi-mi:Zic1(display_short)|uniprotkb:Zic(gene name synonym)|uniprotkb:Zinc finger protein of the cerebellum 1(gene name synonym)	psi-mi:q8k0k3_mouse(display_long)|uniprotkb:Gli2(gene name)|psi-mi:Gli2(display_short)	psi-mi:"MI:0096"(pull down)	Koyabu et al. (2001)	pubmed:11238441|mint:MINT-5213641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-308158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032368(gene)|ensembl:ENSMUST00000034927(transcript)|ensembl:ENSMUST00000065360(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|refseq:NP_033599.2|refseq:XP_006511124.1	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR043359	go:"GO:0005634"(nucleus)|go:"GO:0008589"(regulation of smoothened signaling pathway)	-	-	comment:ZIC1 was GST tagged and GLI2 was Flag tagged. AA 300-384 of ZIC1 is sufficient for its interaction with GLI2.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/03/29	2014/10/16	rogid:oHMuOxYphP8NPdVTH9zxtjMIRTg10090	rogid:SBIGVb7VJHPoJbSpVgKbaLYL5FA10090	intact-crc:007C611AC7B337CF|rigid:6WgekpBnAxPDG12YH/q6YrUu2iQ	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)