#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O54918-3	uniprotkb:Q9NP97	intact:EBI-526084|ensembl:ENSMUSP00000019281|ensembl:ENSMUSP00000099500|intact:EBI-7424890|intact:MINT-89475	intact:EBI-372128|uniprotkb:Q5TC72|uniprotkb:Q96IV3|uniprotkb:Q9NQM2|uniprotkb:B1AKR5|ensembl:ENSP00000349679	psi-mi:o54918-3(display_long)|uniprotkb:Bcl2l11(gene name)|psi-mi:Bcl2l11(display_short)|uniprotkb:Bim(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:dlrb1_human(display_long)|uniprotkb:DYNLRB1(gene name)|psi-mi:DYNLRB1(display_short)|uniprotkb:BITH(gene name synonym)|uniprotkb:DNLC2A(gene name synonym)|uniprotkb:HSPC162(orf name)|uniprotkb:Dynein light chain 2A, cytoplasmic(gene name synonym)|uniprotkb:Dynein-associated protein Km23(gene name synonym)|uniprotkb:Bithoraxoid-like protein(gene name synonym)|uniprotkb:DNCL2A(gene name synonym)|uniprotkb:ROBLD1(gene name synonym)|uniprotkb:Roadblock domain-containing protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Puthalakath et al. (1999)	pubmed:10198631|mint:MINT-5211354	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-526131	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-526067(bim_mouse)|ensembl:ENSMUST00000019281(transcript)|ensembl:ENSMUST00000103211(transcript)|ensembl:ENSMUSG00000027381(gene)	refseq:NP_054902.1|refseq:NP_001268656.1|refseq:NP_001268657.1|refseq:NP_001268658.1|refseq:NP_808852.1|rcsb pdb:2HZ5|rcsb pdb:6F1T|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6RLB|rcsb pdb:6SC2|reactome:R-HSA-5620924|rcsb pdb:2E8J|ensembl:ENSG00000125971(gene)|ensembl:ENST00000357156(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0097542"(ciliary tip)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|rcsb pdb:1Z09|rcsb pdb:2B95	-	-	-	negative:The interaction does not occur under these experimental condition|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/12/25	2014/10/16	rogid:bIpR7awYTDm87yTgIVeDKrUeA6E10090	rogid:jUoW69LtAjTLlqS8J8KH7nImOSQ9606	intact-crc:560837118EA7716B|rigid:br3UNO8CU9si0TWZEs5u4yWFItI	true	-	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9NP97	uniprotkb:O54918-3	intact:EBI-372128|uniprotkb:Q5TC72|uniprotkb:Q96IV3|uniprotkb:Q9NQM2|uniprotkb:B1AKR5|ensembl:ENSP00000349679	intact:EBI-526084|ensembl:ENSMUSP00000019281|ensembl:ENSMUSP00000099500|intact:EBI-7424890|intact:MINT-89475	psi-mi:dlrb1_human(display_long)|uniprotkb:DYNLRB1(gene name)|psi-mi:DYNLRB1(display_short)|uniprotkb:BITH(gene name synonym)|uniprotkb:DNLC2A(gene name synonym)|uniprotkb:HSPC162(orf name)|uniprotkb:Dynein light chain 2A, cytoplasmic(gene name synonym)|uniprotkb:Dynein-associated protein Km23(gene name synonym)|uniprotkb:Bithoraxoid-like protein(gene name synonym)|uniprotkb:DNCL2A(gene name synonym)|uniprotkb:ROBLD1(gene name synonym)|uniprotkb:Roadblock domain-containing protein 1(gene name synonym)	psi-mi:o54918-3(display_long)|uniprotkb:Bcl2l11(gene name)|psi-mi:Bcl2l11(display_short)|uniprotkb:Bim(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Puthalakath et al. (1999)	pubmed:10198631|mint:MINT-5211354	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-526268	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054902.1|refseq:NP_001268656.1|refseq:NP_001268657.1|refseq:NP_001268658.1|refseq:NP_808852.1|rcsb pdb:2HZ5|rcsb pdb:6F1T|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6RLB|rcsb pdb:6SC2|reactome:R-HSA-5620924|rcsb pdb:2E8J|ensembl:ENSG00000125971(gene)|ensembl:ENST00000357156(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0097542"(ciliary tip)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|rcsb pdb:1Z09|rcsb pdb:2B95	intact:EBI-526067(bim_mouse)|ensembl:ENSMUST00000019281(transcript)|ensembl:ENSMUST00000103211(transcript)|ensembl:ENSMUSG00000027381(gene)	-	-	-	negative:The interaction does not occur under these experimental condition|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/12/25	2014/10/16	rogid:jUoW69LtAjTLlqS8J8KH7nImOSQ9606	rogid:bIpR7awYTDm87yTgIVeDKrUeA6E10090	intact-crc:D696CDD79E464C96|rigid:br3UNO8CU9si0TWZEs5u4yWFItI	true	flag tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NP97	uniprotkb:O54918-3	intact:EBI-372128|uniprotkb:Q5TC72|uniprotkb:Q96IV3|uniprotkb:Q9NQM2|uniprotkb:B1AKR5|ensembl:ENSP00000349679	intact:EBI-526084|ensembl:ENSMUSP00000019281|ensembl:ENSMUSP00000099500|intact:EBI-7424890|intact:MINT-89475	psi-mi:dlrb1_human(display_long)|uniprotkb:DYNLRB1(gene name)|psi-mi:DYNLRB1(display_short)|uniprotkb:BITH(gene name synonym)|uniprotkb:DNLC2A(gene name synonym)|uniprotkb:HSPC162(orf name)|uniprotkb:Dynein light chain 2A, cytoplasmic(gene name synonym)|uniprotkb:Dynein-associated protein Km23(gene name synonym)|uniprotkb:Bithoraxoid-like protein(gene name synonym)|uniprotkb:DNCL2A(gene name synonym)|uniprotkb:ROBLD1(gene name synonym)|uniprotkb:Roadblock domain-containing protein 1(gene name synonym)	psi-mi:o54918-3(display_long)|uniprotkb:Bcl2l11(gene name)|psi-mi:Bcl2l11(display_short)|uniprotkb:Bim(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Puthalakath et al. (1999)	pubmed:10198631|mint:MINT-5211354	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-526288	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054902.1|refseq:NP_001268656.1|refseq:NP_001268657.1|refseq:NP_001268658.1|refseq:NP_808852.1|rcsb pdb:2HZ5|rcsb pdb:6F1T|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6RLB|rcsb pdb:6SC2|reactome:R-HSA-5620924|rcsb pdb:2E8J|ensembl:ENSG00000125971(gene)|ensembl:ENST00000357156(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0097542"(ciliary tip)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|rcsb pdb:1Z09|rcsb pdb:2B95	intact:EBI-526067(bim_mouse)|ensembl:ENSMUST00000019281(transcript)|ensembl:ENSMUST00000103211(transcript)|ensembl:ENSMUSG00000027381(gene)	-	-	-	negative:The interaction does not occur under these experimental condition|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2001/12/25	2014/10/16	rogid:jUoW69LtAjTLlqS8J8KH7nImOSQ9606	rogid:bIpR7awYTDm87yTgIVeDKrUeA6E10090	intact-crc:C4A69D3CD803C2BB|rigid:br3UNO8CU9si0TWZEs5u4yWFItI	true	flag tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21127-12	uniprotkb:Q13153	intact:EBI-1018806	intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696	psi-mi:p21127-12(display_long)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L1(gene name synonym)|uniprotkb:PITSLREA(gene name synonym)|uniprotkb:PK58(gene name synonym)|uniprotkb:CDK11B(gene name)|psi-mi:CDK11B(display_short)|uniprotkb:CDC2L1(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 1(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:p58 CLK-1(gene name synonym)|uniprotkb:Cell division protein kinase 11B(gene name synonym)|uniprotkb:CDK11-p58(isoform synonym)	psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2003)	pubmed:12624090	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-604045	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1298(isoform-parent)	refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424	intact:EBI-1331(see-also)	isoform-comment:"Produced by alternative initiation at Met-357 of isoform SV9 via an internal ribosomal entry site (IRES)."	-	comment:PAK1 interacts with the caspase cleaved form of p110PITSLRE, p110C, but not full length p110 PITSLRE or p58PITSLRE|negative:|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2003/08/06	2014/10/16	rogid:vw+GQdj1OPDZ6bKwsoHWDX6BeAo9606	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	intact-crc:B87B9DE10BCB1F39|rigid:hYl2pAZukHCEJqaqjOas22JQ9kU	true	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P21127	uniprotkb:Q13153	intact:EBI-1298|uniprotkb:O95265|uniprotkb:Q12817|uniprotkb:Q12818|uniprotkb:Q12819|uniprotkb:Q12820|uniprotkb:Q12822|uniprotkb:Q8N530|uniprotkb:Q9NZS5|uniprotkb:Q9UBJ0|uniprotkb:Q9UBQ1|uniprotkb:Q9UBR0|uniprotkb:Q9UNY2|uniprotkb:Q9UP57|uniprotkb:Q9UP58|uniprotkb:Q9UP59|uniprotkb:B7ZVY7|uniprotkb:J3KTL7|uniprotkb:J3QR29|uniprotkb:J3QR44|ensembl:ENSP00000464036	intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696	psi-mi:cd11b_human(display_long)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L1(gene name synonym)|uniprotkb:PITSLREA(gene name synonym)|uniprotkb:PK58(gene name synonym)|uniprotkb:CDK11B(gene name)|psi-mi:CDK11B(display_short)|uniprotkb:Cell division cycle 2-like protein kinase 1(gene name synonym)|uniprotkb:p58 CLK-1(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:CDC2L1(gene name synonym)|uniprotkb:Cell division protein kinase 11B(gene name synonym)	psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2003)	pubmed:12624090	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-604055	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_277022.1|refseq:NP_001278274.1|refseq:NP_001778.2|refseq:NP_277021.2|refseq:NP_277024.2|refseq:XP_016858415.1|refseq:NP_277025.1|ensembl:ENSG00000248333(gene)|ensembl:ENST00000407249(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P21127|reactome:R-HSA-380270	refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424	intact:EBI-1331(see-also)	-	-	comment:PAK1 interacts with the caspase cleaved form of p110PITSLRE, p110C, but not full length p110 PITSLRE or p58PITSLRE|negative:|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2003/08/06	2018/04/06	rogid:mwf9SNcd9/lgwTr3OHPqwv/gqV49606	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	intact-crc:A01151A1304011D6|rigid:V5JYiVhgIEkuNq2AY2x4OhluLvE	true	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P63102	uniprotkb:P53668	intact:EBI-354758|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q52KK1|uniprotkb:Q6IRF4|ensembl:ENSRNOP00000030885	intact:EBI-6305595|ensembl:ENSMUSP00000015137	psi-mi:1433z_rat(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Msfs1(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Mitochondrial import stimulation factor S1 subunit(gene name synonym)	psi-mi:limk1_mouse(display_long)|uniprotkb:Limk1(gene name)|psi-mi:Limk1(display_short)|uniprotkb:Limk(gene name synonym)|uniprotkb:KIZ-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Birkenfeld et al. (2003)	pubmed:12323073|mint:MINT-5215773	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8535970|mint:MINT-19350	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3980|refseq:NP_037143.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63102|reactome:R-RNO-111447|reactome:R-RNO-3769402|reactome:R-RNO-392517|reactome:R-RNO-430116|reactome:R-RNO-450604|reactome:R-RNO-512988|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9013700|reactome:R-RNO-9614399|refseq:XP_006241591.1|ensembl:ENSRNOG00000008195(gene)|ensembl:ENSRNOT00000035628(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|dip:DIP-36916N|mint:MINT-721160(identity)	ensembl:ENSMUSG00000029674(gene)|ensembl:ENSMUST00000015137(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-2029482|reactome:R-MMU-399954|reactome:R-MMU-5627123|interpro:IPR036034|refseq:NP_034847.1|mint:MINT-721166(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:domino|comment:mint|negative:true|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/12	2014/10/16	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10116	rogid:+XvZ1/K4JrHoXwFrvd1c13SovI810090	intact-crc:640E4CF5BD6AA575|rigid:kOwSdkEIBox6+fNxNxjenSgLS4c	true	tag:?-?(MINT-721161)	tag:?-?(MINT-721170)|binding-associated region:8-126(MINT-721167)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13526	uniprotkb:P04637	intact:EBI-714158|uniprotkb:Q53X75|ensembl:ENSP00000247970|ensembl:ENSP00000466962|uniprotkb:A8K4V9	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zheng et al. (2002)	mint:MINT-5215847|pubmed:12397361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8551808|mint:MINT-19915	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127445(gene)|ensembl:ENST00000247970(transcript)|ensembl:ENST00000588695(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0016859"(cis-trans isomerase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050808"(synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060393"(regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2Q5A|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:4TNS|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:3IK8|rcsb pdb:4QIB|refseq:NP_006212.1|dip:DIP-29306N|mint:MINT-722254(identity)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|mint:MINT-722260(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/01/08	2014/10/16	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:92E17B9F874C20C8|rigid:XSWhoRekYq0DzRC0xGbReHHLiY8	true	tag:?-?(MINT-722255)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13526	uniprotkb:P04637	intact:EBI-714158|uniprotkb:Q53X75|ensembl:ENSP00000247970|ensembl:ENSP00000466962|uniprotkb:A8K4V9	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zheng et al. (2002)	mint:MINT-5215847|pubmed:12397361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8551826|mint:MINT-19916	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127445(gene)|ensembl:ENST00000247970(transcript)|ensembl:ENST00000588695(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0016859"(cis-trans isomerase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050808"(synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060393"(regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2Q5A|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:4TNS|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:3IK8|rcsb pdb:4QIB|refseq:NP_006212.1|dip:DIP-29306N|mint:MINT-722268(identity)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|mint:MINT-722278(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/01/08	2014/10/16	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:412145182A8C2DE9|rigid:XSWhoRekYq0DzRC0xGbReHHLiY8	true	binding-associated region:?-?(MINT-722269)|tag:?-?(MINT-722273)|mutation:34-34(MINT-722271)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q61686	uniprotkb:Q61686	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamamoto et al. (2003)	pubmed:12565857|mint:MINT-5216088	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596042|mint:MINT-20116	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N|mint:MINT-727199(identity)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N|mint:MINT-727193(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:homomint|comment:domino|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/05	2014/10/16	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:EB9760639EBA991A|rigid:CR+ivbQHK46/g6uOvN7PTcJpN5k	true	mutation decreasing interaction:165-165,168-168(MINT-727203)|binding-associated region:122-174(MINT-727200)|tag:?-?(MINT-727206)	tag:?-?(MINT-727194)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O54864	uniprotkb:Q61686	intact:EBI-302230|uniprotkb:Q3TEW2|uniprotkb:Q3UT51|ensembl:ENSMUSP00000111301|uniprotkb:Q8C2L3|uniprotkb:Q9JLC7|uniprotkb:Q9JLP8	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:suv91_mouse(display_long)|uniprotkb:Suv39h1(gene name)|psi-mi:Suv39h1(display_short)|uniprotkb:Suv39h(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamamoto et al. (2003)	pubmed:12565857|mint:MINT-5216088	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596072|mint:MINT-20117	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000039231(gene)|ensembl:ENSMUST00000115638(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006323"(DNA packaging)|go:"GO:0006342"|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O54864|reactome:R-MMU-3214841|reactome:R-MMU-427359|refseq:NP_035644.1|dip:DIP-32590N|refseq:NP_001277645.1|mint:MINT-727215(identity)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N|mint:MINT-727221(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:SUV39H1 interacts with the molecular surface formed by dimerization of the chromo shadow domain of mHP1small alpha|comment:homomint|comment:domino|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/05	2014/10/16	rogid:1rNfR46yxrh89dwt9QSoHFpdIC010090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:D291DBD595B01E39|rigid:5BKoe4J0Y2h4koUBFqvOjp8cqCo	true	tag:?-?(MINT-727216)	mutation decreasing interaction:168-168,165-165(MINT-727225)|tag:?-?(MINT-727228)|binding-associated region:121-179(MINT-727222)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60953	uniprotkb:P19878	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	intact:EBI-489611|uniprotkb:Q2PP06|uniprotkb:Q8NFC7|ensembl:ENSP00000356505|ensembl:ENSP00000356506|uniprotkb:Q9BV51|uniprotkb:B2R6Q1|uniprotkb:B4DKQ7|uniprotkb:B4DQA7|uniprotkb:E9PHJ2|uniprotkb:E9PHX3	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:ncf2_human(display_long)|uniprotkb:NOXA2(gene name synonym)|uniprotkb:P67PHOX(gene name synonym)|uniprotkb:Neutrophil NADPH oxidase factor 2(gene name synonym)|uniprotkb:NADPH oxidase activator 2(gene name synonym)|uniprotkb:67 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p67-phox(gene name synonym)|uniprotkb:NCF2(gene name)|psi-mi:NCF2(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Lapouge et al. (2000)	pubmed:11090627|mint:MINT-5213243	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-489729	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422	rcsb pdb:2DMO|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|rcsb pdb:1WM5|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034885|interpro:IPR034889|interpro:IPR035546|interpro:IPR036028|mint:P19878|rcsb pdb:1E96|rcsb pdb:1HH8|rcsb pdb:1K4U|rcsb pdb:1OEY|ensembl:ENSG00000116701(gene)|ensembl:ENST00000367535(transcript)|ensembl:ENST00000367536(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032010"(phagolysosome)|refseq:NP_000424.2|refseq:NP_001121123.1|refseq:NP_001177718.1|refseq:XP_011507882.1|refseq:XP_011507883.1|refseq:NP_001177723.1|dip:DIP-76N	intact:EBI-489624(see-also)	-	-	comment:Cdc42 is GMPNP-bound|negative:This experiment relates to a negative interaction	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:UnXrnD0zuJFCfL4g4YPKiskTxzo9606	intact-crc:FC29D0FD6E64AA41|rigid:3QeTd5xmTQPGbAvyb2XCgCZ9EQQ	true	-	binding-associated region:1-203	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35609	uniprotkb:Q9Y561	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Battle et al. (2003)	pubmed:12809483	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-353709	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634	-	-	-	negative:This interaction does not occur under these experimental conditions.|comment:ST7 was V5/His tagged and ACTN2 was HA tagged.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2004/02/19	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606	intact-crc:0DBADF72D1C0E150|rigid:Vtlw/Epjja87AMZp2sBOWBuYJdA	true	ha tag:?-?	v5 tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q9Y561	uniprotkb:Q9UBF9	intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654	intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79	psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym)	psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Battle et al. (2003)	pubmed:12809483	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-353714	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634	go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179	-	-	-	negative:This interaction does not occur under these experimental conditions.|comment:ST7 was V5/His tagged and TTID was HA tagged.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2004/02/19	2014/10/16	rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606	rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606	intact-crc:E71F5E3252F017C5|rigid:b8T0uHT+LE5YCd36VK1Frnf3BYA	true	v5 tag:?-?|his tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:O95295	uniprotkb:Q9Y561	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Battle et al. (2003)	pubmed:12809483	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-353721	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1	refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634	-	-	-	negative:This interaction does not occur under these experimental conditions.|comment:ST7 was V5/His tagged and SNAP25BP was HA tagged.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2004/02/19	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606	intact-crc:8EEA427105F7D152|rigid:sVv0C2rwXIBRC3TPWrxfv+7G8C0	true	ha tag:?-?	v5 tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P05107	uniprotkb:Q9Y3P9	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	intact:EBI-1057545|uniprotkb:Q05CW2|uniprotkb:Q6ZMY1|uniprotkb:Q9HA28|uniprotkb:Q9P0E2|uniprotkb:Q9UG67|intact:EBI-2948690|uniprotkb:B9A6L2|ensembl:ENSP00000362751	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:rbgp1_human(display_long)|uniprotkb:RABGAP1(gene name)|psi-mi:RABGAP1(display_short)|uniprotkb:HSPC094(orf name)|uniprotkb:Rab6 GTPase-activating protein GAPCenA(gene name synonym)|uniprotkb:GAP and centrosome-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8609949|mint:MINT-45904	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-728883(identity)	refseq:XP_011516742.1|refseq:XP_011516743.1|refseq:NP_036329.3|ensembl:ENSG00000011454(gene)|ensembl:ENST00000373647(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0015631"(tubulin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022164|interpro:IPR033185|interpro:IPR035969|mint:Q9Y3P9|rcsb pdb:4NC6|reactome:R-HSA-8854214|refseq:XP_016870056.1|refseq:XP_016870057.1|refseq:XP_016870058.1|mint:MINT-728889(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-t24)|taxid:9606(Homo sapiens T24 bladder carcinoma cells)	-	2004/03/24	2014/10/16	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	rogid:yGnx7q5tyqYfpbeVDwZ8IKI1o+k9606	intact-crc:3A68C69F80B14302|rigid:bpg5aMvbnKp+OSw2tRz9/VCSuKQ	true	tag:?-?(MINT-728884)	binding-associated region:69-206(MINT-728890)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05107	uniprotkb:P35570	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	intact:EBI-520230	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:irs1_rat(display_long)|uniprotkb:pp185(gene name synonym)|uniprotkb:Irs1(gene name)|psi-mi:Irs1(display_short)|uniprotkb:Irs-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8609971|mint:MINT-45938	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729244(identity)	go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|rcsb pdb:5WRK|rcsb pdb:5WRL|rcsb pdb:5WRM|reactome:R-RNO-109704|reactome:R-RNO-112399|reactome:R-RNO-112412|reactome:R-RNO-1257604|reactome:R-RNO-1266695|reactome:R-RNO-198203|reactome:R-RNO-2428928|reactome:R-RNO-5673001|reactome:R-RNO-6811558|reactome:R-RNO-74713|reactome:R-RNO-74749|rgd:2922|refseq:NP_037101.1|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0031000"(response to caffeine)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0090275"(negative regulation of somatostatin secretion)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071478"(cellular response to radiation)|mint:P35570|dip:DIP-664N|mint:MINT-729250(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-t24)|taxid:9606(Homo sapiens T24 bladder carcinoma cells)	-	2004/03/24	2014/10/16	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	rogid:SJ1RT9ubHcFhkPSArSJ6TsPIp0E10116	intact-crc:451505F15A8FC073|rigid:QbgQMvckodkNf62aQ0sg816UTSw	true	tag:?-?(MINT-729245)	binding-associated region:153-257(MINT-729251)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05556	uniprotkb:P98083	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	intact:EBI-300201|ensembl:ENSMUSP00000091940|uniprotkb:Q3U2Q7|uniprotkb:Q8BFY3|uniprotkb:Q8K4C6|uniprotkb:Q8K4C7	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:shc1_mouse(display_long)|uniprotkb:ShcA(gene name synonym)|uniprotkb:Shc1(gene name)|psi-mi:Shc1(display_short)|uniprotkb:Shc(gene name synonym)|uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym)|uniprotkb:SHC-transforming protein A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610457|mint:MINT-45893	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|mint:MINT-729600(identity)	ensembl:ENSMUST00000094378(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENSMUSG00000042626(gene)|go:"GO:0010008"(endosome membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0040008"(regulation of growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|mint:P98083|reactome:R-MMU-1250196|reactome:R-MMU-1250347|reactome:R-MMU-167044|reactome:R-MMU-180336|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2428933|go:"GO:0090322"(regulation of superoxide metabolic process)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990839"(response to endothelin)|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354192|reactome:R-MMU-512988|reactome:R-MMU-5654688|reactome:R-MMU-5654699|reactome:R-MMU-5654704|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|interpro:IPR000980(SH2 motif)|reactome:R-MMU-8851805|reactome:R-MMU-8853659|interpro:IPR006019("Phosphotyrosine interaction (PID or PI)")|reactome:R-MMU-8983432|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029586|interpro:IPR035676|interpro:IPR036860|reactome:R-MMU-9009391|reactome:R-MMU-9020558|reactome:R-MMU-9027284|reactome:R-MMU-9674555|reactome:R-MMU-912526|refseq:NP_001106802.1|refseq:NP_035498.2|dip:DIP-271N|mint:MINT-729606(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:ST3|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:BksNa7XxzDyhK8y6ZdU5tz9CLUU10090	intact-crc:77FD1B22BA2488AE|rigid:enIMSbWUQAbbU8XJLc4hKba0VWk	true	tag:?-?(MINT-729601)	tag:?-?(MINT-729607)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P98083	uniprotkb:P05107	intact:EBI-300201|ensembl:ENSMUSP00000091940|uniprotkb:Q3U2Q7|uniprotkb:Q8BFY3|uniprotkb:Q8K4C6|uniprotkb:Q8K4C7	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	psi-mi:shc1_mouse(display_long)|uniprotkb:ShcA(gene name synonym)|uniprotkb:Shc1(gene name)|psi-mi:Shc1(display_short)|uniprotkb:Shc(gene name synonym)|uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym)|uniprotkb:SHC-transforming protein A(gene name synonym)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610479|mint:MINT-45894	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000094378(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENSMUSG00000042626(gene)|go:"GO:0010008"(endosome membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0040008"(regulation of growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|mint:P98083|reactome:R-MMU-1250196|reactome:R-MMU-1250347|reactome:R-MMU-167044|reactome:R-MMU-180336|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2428933|go:"GO:0090322"(regulation of superoxide metabolic process)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990839"(response to endothelin)|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354192|reactome:R-MMU-512988|reactome:R-MMU-5654688|reactome:R-MMU-5654699|reactome:R-MMU-5654704|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|interpro:IPR000980(SH2 motif)|reactome:R-MMU-8851805|reactome:R-MMU-8853659|interpro:IPR006019("Phosphotyrosine interaction (PID or PI)")|reactome:R-MMU-8983432|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029586|interpro:IPR035676|interpro:IPR036860|reactome:R-MMU-9009391|reactome:R-MMU-9020558|reactome:R-MMU-9027284|reactome:R-MMU-9674555|reactome:R-MMU-912526|refseq:NP_001106802.1|refseq:NP_035498.2|dip:DIP-271N|mint:MINT-729067(identity)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729061(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:ST3|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:BksNa7XxzDyhK8y6ZdU5tz9CLUU10090	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	intact-crc:FDA1D17785E959B4|rigid:80uyn606BCEiITYqrMkfFw+dhS4	true	-	tag:?-?(MINT-729062)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05107	uniprotkb:Q12929	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	intact:EBI-375576|uniprotkb:A6NMC3|ensembl:ENSP00000281172|ensembl:ENSP00000441867|ensembl:ENSP00000442388|ensembl:ENSP00000494689|ensembl:ENSP00000494842|ensembl:ENSP00000495722|ensembl:ENSP00000495824|ensembl:ENSP00000495956|ensembl:ENSP00000496406|ensembl:ENSP00000496516|uniprotkb:Q8N6J0|uniprotkb:B4DX66|uniprotkb:A8K6W2|uniprotkb:A8KA66	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:eps8_human(display_long)|uniprotkb:EPS8(gene name)|psi-mi:EPS8(display_short)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610546|mint:MINT-45897	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729476(identity)	ensembl:ENST00000645775(transcript)|ensembl:ENST00000646828(transcript)|ensembl:ENSG00000151491(gene)|ensembl:ENST00000646918(transcript)|ensembl:ENST00000647087(transcript)|ensembl:ENST00000647224(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|ensembl:ENST00000281172(transcript)|ensembl:ENST00000543523(transcript)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|ensembl:ENST00000543612(transcript)|ensembl:ENST00000642278(transcript)|ensembl:ENST00000644374(transcript)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q12929|rcsb pdb:2E8M|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_004438.3|dip:DIP-32859N|mint:MINT-729482(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	rogid:ulBgb+4uZ7XrN4bLogRtd9I5AbY9606	intact-crc:445314FAE5666294|rigid:TaZEJSuRsr1mglzpvBDdMXSEVXs	true	tag:?-?(MINT-729477)	binding-associated region:59-199(MINT-729483)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12929	uniprotkb:P26010	intact:EBI-375576|uniprotkb:A6NMC3|ensembl:ENSP00000281172|ensembl:ENSP00000441867|ensembl:ENSP00000442388|ensembl:ENSP00000494689|ensembl:ENSP00000494842|ensembl:ENSP00000495722|ensembl:ENSP00000495824|ensembl:ENSP00000495956|ensembl:ENSP00000496406|ensembl:ENSP00000496516|uniprotkb:Q8N6J0|uniprotkb:B4DX66|uniprotkb:A8K6W2|uniprotkb:A8KA66	intact:EBI-702932|ensembl:ENSP00000267082|ensembl:ENSP00000408741|uniprotkb:Q9UCP7|uniprotkb:Q9UCS7	psi-mi:eps8_human(display_long)|uniprotkb:EPS8(gene name)|psi-mi:EPS8(display_short)	psi-mi:itb7_human(display_long)|uniprotkb:Gut homing receptor beta subunit(gene name synonym)|uniprotkb:ITGB7(gene name)|psi-mi:ITGB7(display_short)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610656|mint:MINT-45901	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000645775(transcript)|ensembl:ENST00000646828(transcript)|ensembl:ENSG00000151491(gene)|ensembl:ENST00000646918(transcript)|ensembl:ENST00000647087(transcript)|ensembl:ENST00000647224(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|ensembl:ENST00000281172(transcript)|ensembl:ENST00000543523(transcript)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|ensembl:ENST00000543612(transcript)|ensembl:ENST00000642278(transcript)|ensembl:ENST00000644374(transcript)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q12929|rcsb pdb:2E8M|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_004438.3|dip:DIP-32859N|mint:MINT-728906(identity)	go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072678"(T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015437(Integrin beta-7 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P26010|rcsb pdb:2BRQ|rcsb pdb:3V4P|rcsb pdb:3V4V|reactome:R-HSA-198933|reactome:R-HSA-216083|ensembl:ENSG00000139626(gene)|ensembl:ENST00000267082(transcript)|ensembl:ENST00000422257(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003366"(cell-matrix adhesion involved in ameboidal cell migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034669"(integrin alpha4-beta7 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0046872"(metal ion binding)|refseq:NP_000880.1|refseq:XP_005268908.1|refseq:XP_005268909.1|dip:DIP-34970N|mint:MINT-728900(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:ulBgb+4uZ7XrN4bLogRtd9I5AbY9606	rogid:mRv+7ZBLDgWEfr8pRV70UUUedgM9606	intact-crc:AAAB67B694CDCA6A|rigid:Ct61DdX8CiBPONfV5xN7xbkUCs0	true	binding-associated region:59-199(MINT-728907)	tag:?-?(MINT-728901)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G8	uniprotkb:P05107	intact:EBI-7876312|uniprotkb:Q5XLJ0|intact:MINT-4903813|intact:MINT-4918769|uniprotkb:B4DH98|uniprotkb:A5PKY5|uniprotkb:F8VZR9|uniprotkb:F8VPM3|uniprotkb:A8MSN4|uniprotkb:A8K153|uniprotkb:Q6NUS4|intact:MINT-1492880|uniprotkb:Q7Z6G7|uniprotkb:Q6IVB5|uniprotkb:A7E259|uniprotkb:Q7Z6G6|uniprotkb:Q8TAP3|intact:MINT-258807|uniprotkb:F8WC27|uniprotkb:Q9NRX7|uniprotkb:Q9Y5K9|uniprotkb:B4DFP6|ensembl:ENSP00000449629	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	psi-mi:ans1b_human(display_long)|uniprotkb:ANKS1B(gene name)|psi-mi:ANKS1B(display_short)|uniprotkb:Amyloid-beta protein intracellular domain-associated protein 1(gene name synonym)|uniprotkb:E2A-PBX1-associated protein(gene name synonym)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610846|mint:MINT-45909	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001190994.1|refseq:NP_064525.1|refseq:NP_001191008.1|refseq:NP_001191009.1|refseq:NP_001191010.1|refseq:NP_001190999.1|refseq:NP_001190995.1|refseq:NP_001190996.1|refseq:NP_001190998.1|refseq:NP_001190997.1|refseq:NP_690001.3|refseq:NP_858056.2|ensembl:ENSG00000185046(gene)|ensembl:ENST00000547776(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:1900383"(regulation of synaptic plasticity by receptor localization to synapse)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR033636|interpro:IPR036770|interpro:IPR041880|interpro:IPR041882|rcsb pdb:2EAM|rcsb pdb:2KE7|rcsb pdb:2KIV|rcsb pdb:2M38|dip:DIP-41406N|mint:MINT-729429(identity)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729423(identity)	-	function:Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells|function:Isoform 3 can regulate global protein synthesis by altering nucleolar numbers|function:Isoform 4 may play a role as a modulator of APP processing. Overexpression of isoform 4 can down-regulate APP processing|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:S/D2te61NTyW2f9ivzPFqIB1/NM9606	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	intact-crc:2BB169DF37F74597|rigid:cysmf0Xp2BJPAwE3girBQybeBXE	true	binding-associated region:761-903(MINT-729430)	tag:?-?(MINT-729424)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05556	uniprotkb:Q9UBP9	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	intact:EBI-3922283|uniprotkb:Q9BVL3|uniprotkb:B2RB51|uniprotkb:Q53RF3|uniprotkb:Q53PC1|uniprotkb:D3DPH1|uniprotkb:B8ZZ72|uniprotkb:B4DQ40|uniprotkb:E9PB86|ensembl:ENSP00000352047|ensembl:ENSP00000386289|ensembl:ENSP00000386732|ensembl:ENSP00000386867	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:gulp1_human(display_long)|uniprotkb:GULP1(gene name)|psi-mi:GULP1(display_short)|uniprotkb:CED6(gene name synonym)|uniprotkb:GULP(gene name synonym)|uniprotkb:Cell death protein 6 homolog(gene name synonym)|uniprotkb:PTB domain adapter protein CED-6(gene name synonym)|uniprotkb:Protein GULP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610904|mint:MINT-45911	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|mint:MINT-729299(identity)	refseq:NP_057399.1|refseq:NP_001239598.1|refseq:NP_001239597.1|refseq:XP_016859795.1|ensembl:ENSG00000144366(gene)|ensembl:ENST00000359135(transcript)|ensembl:ENST00000409580(transcript)|ensembl:ENST00000409609(transcript)|ensembl:ENST00000409830(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006869"(lipid transport)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:6ITU|mint:MINT-729305(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:d8WIyZvwLJGs0CGArWArKium7Zw9606	intact-crc:2EF64FB4C2E662DF|rigid:fxs5RUjD9yuF57NftM4XSdYC+KI	true	tag:?-?(MINT-729300)	binding-associated region:20-160(MINT-729306)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05107	uniprotkb:Q9UBP9	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	intact:EBI-3922283|uniprotkb:Q9BVL3|uniprotkb:B2RB51|uniprotkb:Q53RF3|uniprotkb:Q53PC1|uniprotkb:D3DPH1|uniprotkb:B8ZZ72|uniprotkb:B4DQ40|uniprotkb:E9PB86|ensembl:ENSP00000352047|ensembl:ENSP00000386289|ensembl:ENSP00000386732|ensembl:ENSP00000386867	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:gulp1_human(display_long)|uniprotkb:GULP1(gene name)|psi-mi:GULP1(display_short)|uniprotkb:CED6(gene name synonym)|uniprotkb:GULP(gene name synonym)|uniprotkb:Cell death protein 6 homolog(gene name synonym)|uniprotkb:PTB domain adapter protein CED-6(gene name synonym)|uniprotkb:Protein GULP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610927|mint:MINT-45912	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729688(identity)	refseq:NP_057399.1|refseq:NP_001239598.1|refseq:NP_001239597.1|refseq:XP_016859795.1|ensembl:ENSG00000144366(gene)|ensembl:ENST00000359135(transcript)|ensembl:ENST00000409580(transcript)|ensembl:ENST00000409609(transcript)|ensembl:ENST00000409830(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006869"(lipid transport)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:6ITU|mint:MINT-729694(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	rogid:d8WIyZvwLJGs0CGArWArKium7Zw9606	intact-crc:E393430E83280E27|rigid:3No4idzwvIha7f2fPYKUWn4tXn8	true	tag:?-?(MINT-729689)	binding-associated region:20-160(MINT-729695)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14924	uniprotkb:P26010	intact:EBI-7358493|intact:MINT-154790|uniprotkb:B1AQ31|uniprotkb:O14923|uniprotkb:B1AQ32|uniprotkb:O14922|uniprotkb:O75338|uniprotkb:O43510|uniprotkb:B1AQ30|uniprotkb:E7EMN9|uniprotkb:Q147X0|uniprotkb:Q8WX95|ensembl:ENSP00000338509|ensembl:ENSP00000339381|uniprotkb:B7Z764	intact:EBI-702932|ensembl:ENSP00000267082|ensembl:ENSP00000408741|uniprotkb:Q9UCP7|uniprotkb:Q9UCS7	psi-mi:rgs12_human(display_long)|uniprotkb:RGS12(gene name)|psi-mi:RGS12(display_short)	psi-mi:itb7_human(display_long)|uniprotkb:Gut homing receptor beta subunit(gene name synonym)|uniprotkb:ITGB7(gene name)|psi-mi:ITGB7(display_short)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8610993|mint:MINT-45915	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511845.1|refseq:NP_002917.1|refseq:NP_937872.1|refseq:NP_937870.1|refseq:XP_016864018.1|refseq:XP_016864020.1|refseq:XP_016864021.1|refseq:XP_016864022.1|ensembl:ENSG00000159788(gene)|ensembl:ENST00000336727(transcript)|ensembl:ENST00000344733(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003109(GoLoco)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036034|interpro:IPR036305|interpro:IPR037880|rcsb pdb:2EBZ|rcsb pdb:2KV8|reactome:R-HSA-418594|refseq:XP_006713968.1|refseq:XP_006713969.1|refseq:XP_006713970.1|mint:MINT-728722(identity)	go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072678"(T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015437(Integrin beta-7 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P26010|rcsb pdb:2BRQ|rcsb pdb:3V4P|rcsb pdb:3V4V|reactome:R-HSA-198933|reactome:R-HSA-216083|ensembl:ENSG00000139626(gene)|ensembl:ENST00000267082(transcript)|ensembl:ENST00000422257(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003366"(cell-matrix adhesion involved in ameboidal cell migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034669"(integrin alpha4-beta7 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0046872"(metal ion binding)|refseq:NP_000880.1|refseq:XP_005268908.1|refseq:XP_005268909.1|dip:DIP-34970N|mint:MINT-728716(identity)	-	function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:86ann2gpd8ZhURj5bP5EhPwz9Fo9606	rogid:mRv+7ZBLDgWEfr8pRV70UUUedgM9606	intact-crc:417295DE77C16EA3|rigid:YQGJS9JBwQtlpoaE/y18/H7nOE0	true	binding-associated region:224-376(MINT-728723)	tag:?-?(MINT-728717)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9QZS3	uniprotkb:P05107	intact:EBI-3895976|uniprotkb:P70422|uniprotkb:Q8CIB1|uniprotkb:Q9DC57|uniprotkb:Q9QZR1|uniprotkb:Q9QZS4|ensembl:ENSMUSP00000119303	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	psi-mi:numb_mouse(display_long)|uniprotkb:Numb(gene name)|psi-mi:Numb(display_short)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8611039|mint:MINT-45917	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011242314.1|refseq:NP_001129547.1|refseq:NP_035079.1|refseq:XP_006515639.1|refseq:XP_006515640.1|refseq:XP_006515641.1|refseq:NP_001258984.1|refseq:NP_001258985.1|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|rcsb pdb:1WJ1|rcsb pdb:5YQG|reactome:R-MMU-437239|reactome:R-MMU-5610780|reactome:R-MMU-5632684|ensembl:ENSMUSG00000021224(gene)|ensembl:ENSMUST00000129335(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030136"(clathrin-coated vesicle)|mint:MINT-729322(identity)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729316(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:ST3|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:k5R3OgcJeaRwSxIspTbH48zRztk10090	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	intact-crc:61568401A2C5C714|rigid:RwLY49aelVXQaZxbO/XNtkIWSvk	true	binding-associated region:39-172(MINT-729323)	tag:?-?(MINT-729317)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14924	uniprotkb:P05556	intact:EBI-7358493|intact:MINT-154790|uniprotkb:B1AQ31|uniprotkb:O14923|uniprotkb:B1AQ32|uniprotkb:O14922|uniprotkb:O75338|uniprotkb:O43510|uniprotkb:B1AQ30|uniprotkb:E7EMN9|uniprotkb:Q147X0|uniprotkb:Q8WX95|ensembl:ENSP00000338509|ensembl:ENSP00000339381|uniprotkb:B7Z764	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:rgs12_human(display_long)|uniprotkb:RGS12(gene name)|psi-mi:RGS12(display_short)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8611840|mint:MINT-45935	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511845.1|refseq:NP_002917.1|refseq:NP_937872.1|refseq:NP_937870.1|refseq:XP_016864018.1|refseq:XP_016864020.1|refseq:XP_016864021.1|refseq:XP_016864022.1|ensembl:ENSG00000159788(gene)|ensembl:ENST00000336727(transcript)|ensembl:ENST00000344733(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003109(GoLoco)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036034|interpro:IPR036305|interpro:IPR037880|rcsb pdb:2EBZ|rcsb pdb:2KV8|reactome:R-HSA-418594|refseq:XP_006713968.1|refseq:XP_006713969.1|refseq:XP_006713970.1|mint:MINT-729569(identity)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|mint:MINT-729563(identity)	-	function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F1|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:86ann2gpd8ZhURj5bP5EhPwz9Fo9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:82251602A4EB9988|rigid:9J/r3eeVH/TPgPaZsNXukwxz8P8	true	binding-associated region:224-376(MINT-729570)	tag:?-?(MINT-729564)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UQF2	uniprotkb:P05107	intact:EBI-78404|ensembl:ENSP00000241014|uniprotkb:O43407|uniprotkb:D3DQP4	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	psi-mi:jip1_human(display_long)|uniprotkb:MAPK8IP1(gene name)|psi-mi:MAPK8IP1(display_short)|uniprotkb:IB1(gene name synonym)|uniprotkb:JIP1(gene name synonym)|uniprotkb:PRKM8IP(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Islet-brain 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8612270|mint:MINT-45956	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000121653(gene)|ensembl:ENST00000241014(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044302"(dentate gyrus mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|mint:Q9UQF2|rcsb pdb:2G01|rcsb pdb:2GMX|rcsb pdb:2H96|rcsb pdb:3OXI|rcsb pdb:3PTG|rcsb pdb:3VUD|rcsb pdb:3VUG|rcsb pdb:3VUH|rcsb pdb:3VUI|rcsb pdb:3VUK|rcsb pdb:3VUL|rcsb pdb:3VUM|rcsb pdb:4E73|rcsb pdb:4G1W|rcsb pdb:4H39|rcsb pdb:4HYS|rcsb pdb:4HYU|rcsb pdb:4IZY|interpro:IPR035638|rcsb pdb:5LW1|rcsb pdb:6FUZ|refseq:NP_005447.1|mint:MINT-729499(identity)	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|mint:MINT-729493(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:ST3|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:16oAQc3NvvW+txnZndjUcFEl7ZQ9606	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	intact-crc:A5C712F81986444C|rigid:S0P11fRJaxaYLaxP3+KW6uNYeoY	true	tag:?-?(MINT-729502)|binding-associated region:567-701(MINT-729500)	tag:?-?(MINT-729494)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UQF2	uniprotkb:P26010	intact:EBI-78404|ensembl:ENSP00000241014|uniprotkb:O43407|uniprotkb:D3DQP4	intact:EBI-702932|ensembl:ENSP00000267082|ensembl:ENSP00000408741|uniprotkb:Q9UCP7|uniprotkb:Q9UCS7	psi-mi:jip1_human(display_long)|uniprotkb:MAPK8IP1(gene name)|psi-mi:MAPK8IP1(display_short)|uniprotkb:IB1(gene name synonym)|uniprotkb:JIP1(gene name synonym)|uniprotkb:PRKM8IP(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Islet-brain 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)	psi-mi:itb7_human(display_long)|uniprotkb:Gut homing receptor beta subunit(gene name synonym)|uniprotkb:ITGB7(gene name)|psi-mi:ITGB7(display_short)	psi-mi:"MI:0096"(pull down)	Calderwood et al. (2003)	mint:MINT-5216162|pubmed:12606711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8612319|mint:MINT-45958	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000121653(gene)|ensembl:ENST00000241014(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044302"(dentate gyrus mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|mint:Q9UQF2|rcsb pdb:2G01|rcsb pdb:2GMX|rcsb pdb:2H96|rcsb pdb:3OXI|rcsb pdb:3PTG|rcsb pdb:3VUD|rcsb pdb:3VUG|rcsb pdb:3VUH|rcsb pdb:3VUI|rcsb pdb:3VUK|rcsb pdb:3VUL|rcsb pdb:3VUM|rcsb pdb:4E73|rcsb pdb:4G1W|rcsb pdb:4H39|rcsb pdb:4HYS|rcsb pdb:4HYU|rcsb pdb:4IZY|interpro:IPR035638|rcsb pdb:5LW1|rcsb pdb:6FUZ|refseq:NP_005447.1|mint:MINT-729747(identity)	go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072678"(T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015437(Integrin beta-7 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P26010|rcsb pdb:2BRQ|rcsb pdb:3V4P|rcsb pdb:3V4V|reactome:R-HSA-198933|reactome:R-HSA-216083|ensembl:ENSG00000139626(gene)|ensembl:ENST00000267082(transcript)|ensembl:ENST00000422257(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003366"(cell-matrix adhesion involved in ameboidal cell migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034669"(integrin alpha4-beta7 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0046872"(metal ion binding)|refseq:NP_000880.1|refseq:XP_005268908.1|refseq:XP_005268909.1|dip:DIP-34970N|mint:MINT-729741(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:ST3|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/24	2014/10/16	rogid:16oAQc3NvvW+txnZndjUcFEl7ZQ9606	rogid:mRv+7ZBLDgWEfr8pRV70UUUedgM9606	intact-crc:63AAD98F2D358327|rigid:2y1DSsowrSg5lFLVZZBSigTcxyo	true	binding-associated region:567-701(MINT-729748)|tag:?-?(MINT-729751)	tag:?-?(MINT-729742)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25208	uniprotkb:P56524	intact:EBI-389728|uniprotkb:Q96IY8|uniprotkb:A8K7B9|ensembl:ENSP00000240055|ensembl:ENSP00000447486	intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606	psi-mi:nfyb_human(display_long)|uniprotkb:NFYB(gene name)|psi-mi:NFYB(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit B(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit B(gene name synonym)	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Borghi et al. (2001)	pubmed:11792813|mint:MINT-5215014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8075377|mint:MINT-49705	intact-miscore:0.27	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006157.1|ensembl:ENSG00000120837(gene)|ensembl:ENST00000240055(transcript)|ensembl:ENST00000551727(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003956(Transcription factor, NFYB/HAP3, conserved site)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027113|rcsb pdb:1N1J|rcsb pdb:4AWL|rcsb pdb:4CSR|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|mint:MINT-1753773(identity)	ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|mint:MINT-1753777(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/04/27	2014/10/16	rogid:jrpRDalhDSJX1wE0hWDSC8lawJU9606	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	intact-crc:650A20A22EB20764|rigid:o3MtyVkSQYtSeGwaUHIXjH6ties	true	-	tag:?-?(MINT-1753778)	-	-	psi-mi:"MI:0363"(inferred by author)	psi-mi:"MI:0363"(inferred by author)
uniprotkb:B2RU80	uniprotkb:O88792	intact:EBI-7087472|ensembl:ENSMUSP00000089805|uniprotkb:Q3UGZ7|uniprotkb:Q8CIW2|intact:MINT-247274|intact:MINT-8298798	intact:EBI-7580837|intact:MINT-247376|uniprotkb:Q8VC39|intact:MINT-4119377|ensembl:ENSMUSP00000041907	psi-mi:ptprb_mouse(display_long)|uniprotkb:Ptprb(gene name)|psi-mi:Ptprb(display_short)|uniprotkb:Vascular endothelial protein tyrosine phosphatase(gene name synonym)	psi-mi:jam1_mouse(display_long)|uniprotkb:F11r(gene name)|psi-mi:F11r(display_short)|uniprotkb:Jam1(gene name synonym)|uniprotkb:Jcam(gene name synonym)|uniprotkb:Jcam1(gene name synonym)|uniprotkb:Junctional adhesion molecule 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nawroth et al. (2002)	mint:MINT-5215744|pubmed:12234928	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8530314|mint:MINT-49816	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020154(gene)|ensembl:ENSMUST00000092167(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-MMU-6798695|refseq:NP_084204.2|mint:MINT-720866(identity)	refseq:NP_766235.1|ensembl:ENSMUSG00000038235(gene)|ensembl:ENSMUST00000043839(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009314"(response to radiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035683"(memory T cell extravasation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR042456|mint:O88792|rcsb pdb:1F97|reactome:R-MMU-202733|reactome:R-MMU-216083|reactome:R-MMU-2173791|reactome:R-MMU-420029|go:"GO:0098609"(cell-cell adhesion)|dip:DIP-41166N|mint:MINT-720872(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:mint|negative:true|partial coverage:partial coverage	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/05/24	2014/10/16	rogid:aQEta8FlG3ri6i9330xKJf854qw10090	rogid:eM6EU7qHKBw4lJ4jpg5388hIza010090	intact-crc:BD0198E36904AA65|rigid:OQQfDOy3r5v/zZkshVmy4/gdCVU	true	tag:?-?(MINT-720867)	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:B2RU80	uniprotkb:P35222	intact:EBI-7087472|ensembl:ENSMUSP00000089805|uniprotkb:Q3UGZ7|uniprotkb:Q8CIW2|intact:MINT-247274|intact:MINT-8298798	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:ptprb_mouse(display_long)|uniprotkb:Ptprb(gene name)|psi-mi:Ptprb(display_short)|uniprotkb:Vascular endothelial protein tyrosine phosphatase(gene name synonym)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nawroth et al. (2002)	mint:MINT-5215744|pubmed:12234928	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8530299|mint:MINT-49815	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020154(gene)|ensembl:ENSMUST00000092167(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-MMU-6798695|refseq:NP_084204.2|mint:MINT-720829(identity)	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|mint:MINT-720835(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:The article mentions that in similar co-precipitation exp, interaction between these two proteins was actually found.|comment:mint|negative:true|partial coverage:partial coverage	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/05/24	2014/10/16	rogid:aQEta8FlG3ri6i9330xKJf854qw10090	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	intact-crc:970777AF468CBECB|rigid:ptXkHekjjvqh/5JE2pQ6p02/j0U	true	tag:?-?(MINT-720830)	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P20701	uniprotkb:Q96S59	intact:EBI-961214|ensembl:ENSP00000349252|uniprotkb:O43746|uniprotkb:Q45H73|uniprotkb:Q9UBC8|intact:EBI-3962403|uniprotkb:Q96HB1	intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1	psi-mi:ital_human(display_long)|uniprotkb:ITGAL(gene name)|psi-mi:ITGAL(display_short)|uniprotkb:CD11A(gene name synonym)|uniprotkb:Leukocyte adhesion glycoprotein LFA-1 alpha chain(gene name synonym)|uniprotkb:Leukocyte function-associated molecule 1 alpha chain(gene name synonym)|uniprotkb:CD11 antigen-like family member A(gene name synonym)	psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Denti et al. (2004)	pubmed:14722085|mint:MINT-5216861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7086968|mint:MINT-50056	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002200.2|ensembl:ENSG00000005844(gene)|ensembl:ENST00000356798(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035683"(memory T cell extravasation)|go:"GO:0043113"(receptor clustering)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1CQP|rcsb pdb:1DGQ|rcsb pdb:1IJ4|rcsb pdb:1LFA|rcsb pdb:1MJN|rcsb pdb:1MQ8|rcsb pdb:1MQ9|rcsb pdb:1MQA|rcsb pdb:1RD4|rcsb pdb:1T0P|rcsb pdb:1XDD|rcsb pdb:1XDG|rcsb pdb:1XUO|rcsb pdb:1ZON|rcsb pdb:1ZOO|rcsb pdb:1ZOP|rcsb pdb:2ICA|rcsb pdb:2K8O|rcsb pdb:2M3E|rcsb pdb:2O7N|rcsb pdb:3BN3|rcsb pdb:3BQM|rcsb pdb:3BQN|rcsb pdb:3E2M|rcsb pdb:3EOA|rcsb pdb:3EOB|rcsb pdb:3F74|rcsb pdb:3HI6|rcsb pdb:3F78|rcsb pdb:3M6F|rcsb pdb:3TCX|rcsb pdb:4IXD|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:6BXB|rcsb pdb:6BXF|rcsb pdb:6BXJ|rcsb pdb:6CKB|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6798695|reactome:R-HSA-8949275|refseq:NP_001107852.1|dip:DIP-623N|mint:MINT-1130736(identity)	refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1|mint:MINT-1130732(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/07/13	2014/10/16	rogid:JeiBJZbkw8mtrE7WrFlkepPiAOY9606	rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606	intact-crc:2FE44D6707CC3A96|rigid:nNbbmk6DsaqFzxaCZHxhPaCdX5A	true	tag:?-?(MINT-1130737)	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P97814	uniprotkb:P70315	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wu et al. (1998)	pubmed:9488710|mint:MINT-6547635	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8678747|mint:MINT-50155	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1532754(identity)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N|mint:MINT-1532762(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/07/28	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	intact-crc:6EB2F96E84F78488|rigid:vJDvGr77jnuqjolaadJ1jZ9pMxM	true	tag:?-?(MINT-1532757)|O4'-phospho-L-tyrosine:367-367(MINT-1532755)	binding-associated region:367-443(MINT-1532763)|tag:?-?(MINT-1532765)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25604	uniprotkb:P52917	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769688|mint:MINT-50305	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468333(identity)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|mint:MINT-468339(identity)	-	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	crc64:E65BCDB19C9510DD|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	intact-crc:830D61BB2549EFFB|rigid:FD5LPXxBOVV89jTONhod9h0vbiQ	true	tag:?-?(MINT-468334)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9P7F7	uniprotkb:P25604	intact:EBI-7769798|ensemblfungi:"SPAC1142.07c.1:pep"|intact:MINT-468312	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	psi-mi:snf7_schpo(display_long)|uniprotkb:snf7(gene name)|psi-mi:snf7(display_short)|uniprotkb:vps32(gene name synonym)|uniprotkb:SPAC1142.07c(orf name)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769793|mint:MINT-50307	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-1632852|reactome:R-SPO-917729|ensemblfungi:SPAC1142.07c(gene)|ensemblfungi:SPAC1142.07c.1(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|refseq:NP_594271.1|interpro:IPR005024(Snf7)|reactome:R-SPO-9668328|mint:MINT-468326(identity)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468320(identity)	-	function:"Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB)"|comment:mint|comment:"Stoichiometry: 1.0"	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:vm71xGBSGFui19WZ5oWLutT2KjE284812	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	intact-crc:2E16718D9F1F4B25|rigid:mZ4hK8MZIdkgPTF3LEleLbCWYu0	true	-	tag:?-?(MINT-468321)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25604	uniprotkb:P36095	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769729|mint:MINT-50306	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468364(identity)	refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|mint:MINT-468370(identity)	-	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	crc64:6073C1B680D58E98|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292	intact-crc:28F3DFCF87B125D0|rigid:SPcYyXHPFHOu/wiiApqLGr9J7vM	true	tag:?-?(MINT-468365)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P02299	uniprotkb:P20659	intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112	intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604	psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short)	psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Czermin et al. (2002)	pubmed:12408863|mint:MINT-5215869	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8553781|mint:MINT-50331	intact-miscore:0.31	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662086(identity)	ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662081(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1B|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/10	2014/10/16	rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227	rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227	intact-crc:06E87F9346D056B2|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk	true	N6,N6-dimethyl-L-lysine:4-4(MINT-1662089)|binding-associated region:1-19(MINT-1662087)	-	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42124	uniprotkb:P02299	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short)	psi-mi:"MI:0045"(experimental interaction detection)	Czermin et al. (2002)	pubmed:12408863|mint:MINT-5215869	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8553761|mint:MINT-50330	intact-miscore:0.31	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573588(identity)	refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573593(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1C|negative:the interactions are not observed under these experimental conditions|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/10	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227	intact-crc:3567D775920FA5AA|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI	true	-	N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1573596)|binding-associated region:1-19(MINT-1573594)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P20659	uniprotkb:P02299	intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604	intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112	psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short)	psi-mi:"MI:0045"(experimental interaction detection)	Czermin et al. (2002)	pubmed:12408863|mint:MINT-5215869	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8553847|mint:MINT-50335	intact-miscore:0.31	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662157(identity)	refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662162(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|resulting-ptm:N6@N6-dimethyl-L-lysine 9|resulting-ptm:N6@N6-dimethyl-L-lysine 4|comment:homomint|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/10	2014/10/16	rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227	rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227	intact-crc:1492BB3C9898CB79|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk	true	-	binding-associated region:1-19(MINT-1662163)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P01112	uniprotkb:P06241	intact:EBI-350145|uniprotkb:Q9BR65|uniprotkb:Q14080|uniprotkb:Q6FHV9|uniprotkb:B5BUA0|uniprotkb:Q9UCE2|ensembl:ENSP00000309845|ensembl:ENSP00000380723|ensembl:ENSP00000407586|ensembl:ENSP00000480686|ensembl:ENSP00000482366|ensembl:ENSP00000488757	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:rash_human(display_long)|uniprotkb:HRAS(gene name)|psi-mi:HRAS(display_short)|uniprotkb:HRAS1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:p21ras(gene name synonym)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:Ha-Ras(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thornton et al. (2003)	mint:MINT-5216326|pubmed:12695509	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8633243|mint:MINT-50377	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123914.1|refseq:NP_005334.1|refseq:NP_789765.1|ensembl:ENSG00000174775(gene)|ensembl:ENSG00000276536(gene)|ensembl:ENST00000311189(transcript)|ensembl:ENST00000397596(transcript)|ensembl:ENST00000451590(transcript)|ensembl:ENST00000610977(transcript)|ensembl:ENST00000615062(transcript)|ensembl:ENST00000631404(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01112|rcsb pdb:121P|rcsb pdb:1AA9|rcsb pdb:1AGP|rcsb pdb:1BKD|rcsb pdb:1CLU|rcsb pdb:1CRP|rcsb pdb:1CRQ|rcsb pdb:1CRR|rcsb pdb:1CTQ|rcsb pdb:1GNP|rcsb pdb:1GNQ|rcsb pdb:1GNR|rcsb pdb:1HE8|rcsb pdb:1IAQ|rcsb pdb:1IOZ|rcsb pdb:1JAH|rcsb pdb:1JAI|rcsb pdb:1K8R|rcsb pdb:1LF0|rcsb pdb:1LF5|rcsb pdb:1LFD|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1P2S|rcsb pdb:1P2T|rcsb pdb:1P2U|rcsb pdb:1P2V|rcsb pdb:1PLJ|rcsb pdb:1PLK|rcsb pdb:1PLL|rcsb pdb:1Q21|rcsb pdb:1QRA|rcsb pdb:1RVD|rcsb pdb:1WQ1|rcsb pdb:1XCM|rcsb pdb:1XD2|rcsb pdb:1XJ0|rcsb pdb:1ZVQ|rcsb pdb:1ZW6|rcsb pdb:221P|rcsb pdb:2C5L|rcsb pdb:2CE2|rcsb pdb:2CL0|rcsb pdb:2CL6|rcsb pdb:2CL7|rcsb pdb:2CLC|rcsb pdb:2CLD|rcsb pdb:2EVW|rcsb pdb:2GDP|rcsb pdb:2LCF|rcsb pdb:2LWI|rcsb pdb:2N42|rcsb pdb:2N46|rcsb pdb:2Q21|rcsb pdb:2QUZ|rcsb pdb:2RGA|rcsb pdb:2RGB|rcsb pdb:2RGC|rcsb pdb:2RGD|rcsb pdb:2RGE|rcsb pdb:2RGG|rcsb pdb:2UZI|rcsb pdb:2VH5|rcsb pdb:2X1V|rcsb pdb:3DDC|rcsb pdb:3I3S|rcsb pdb:3K8Y|rcsb pdb:3K9L|rcsb pdb:3K9N|rcsb pdb:3KKM|rcsb pdb:3KKN|rcsb pdb:3KUD|rcsb pdb:3L8Y|rcsb pdb:3L8Z|rcsb pdb:3LBH|rcsb pdb:3LBI|rcsb pdb:3LBN|rcsb pdb:3LO5|rcsb pdb:3OIU|rcsb pdb:3OIV|rcsb pdb:3OIW|rcsb pdb:3RRY|rcsb pdb:3RRZ|rcsb pdb:3RS0|rcsb pdb:3RS2|rcsb pdb:3RS3|rcsb pdb:3RS4|rcsb pdb:3RS5|rcsb pdb:3RS7|rcsb pdb:3RSL|rcsb pdb:3RSO|rcsb pdb:3TGP|rcsb pdb:421P|rcsb pdb:4DLR|rcsb pdb:4DLS|rcsb pdb:4DLT|rcsb pdb:4DLU|rcsb pdb:4DLV|rcsb pdb:4DLW|rcsb pdb:4DLX|rcsb pdb:4DLY|rcsb pdb:4DLZ|rcsb pdb:4DST|rcsb pdb:4DSU|rcsb pdb:4EFL|rcsb pdb:4EFM|rcsb pdb:4EFN|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4K81|rcsb pdb:4L9S|rcsb pdb:4L9W|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4Q21|rcsb pdb:4RSG|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:4XVQ|rcsb pdb:4XVR|rcsb pdb:521P|rcsb pdb:5B2Z|rcsb pdb:5B30|rcsb pdb:5E95|rcsb pdb:5P21|rcsb pdb:5VBE|rcsb pdb:5VBZ|rcsb pdb:5WDO|rcsb pdb:5WDP|rcsb pdb:5WDQ|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-3928662|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6Q21|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:5WPL|rcsb pdb:5X9S|rcsb pdb:5ZC6|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:621P|rcsb pdb:6AMB|rcsb pdb:6AXG|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D55|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6DZH|rcsb pdb:6E6C|rcsb pdb:6E6P|rcsb pdb:6MQT|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6ZJ0|rcsb pdb:6ZL3|rcsb pdb:721P|rcsb pdb:7JHP|rcsb pdb:7L0F|rcsb pdb:7L0G|rcsb pdb:821P|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|refseq:NP_001304983.1|dip:DIP-1050N|mint:MINT-733180(identity)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439|mint:MINT-733186(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/21	2014/10/16	rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw9606	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:1E8520E4C525A0A7|rigid:Rr7BwyHE5xzCzMbry8dYqGTdmpo	true	tag:?-?(MINT-733181)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2H9-1	uniprotkb:P51617-2	intact:EBI-448466|ensembl:ENSP00000322532	intact:EBI-487391|ensembl:ENSP00000377291	psi-mi:q8n2h9-1(display_long)|uniprotkb:PELI3(gene name)|psi-mi:PELI3(display_short)|uniprotkb:RING-type E3 ubiquitin transferase pellino homolog 3(gene name synonym)|uniprotkb:A(isoform synonym)|uniprotkb:Alpha(isoform synonym)	psi-mi:p51617-2(display_long)|uniprotkb:b(isoform synonym)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jensen et al. (2003)	pubmed:12874243	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-969296	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-448457(peli3_human)|ensembl:ENSG00000174516(gene)|ensembl:ENST00000320740(transcript)	intact:EBI-358664(irak1_human)|ensembl:ENSG00000184216(gene)|ensembl:ENST00000393687(transcript)	go:"GO:0019221"(cytokine-mediated signaling pathway)	-	isoform-comment:Inactive.	comment:Interacts with P51617-1 but not P51617-2|negative:|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2004/10/14	2014/10/16	rogid:rj8IvjYfW2mL1sK2/f6O2cinMNo9606	rogid:/c+EKWiXR9AEsPeAwhHFHY5DRIo9606	intact-crc:3890102C5D6E5BD9|rigid:knmL/0+FEYQFtJsKOHuWWjzO5fw	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N2W9	uniprotkb:Q6Q0C0	intact:EBI-473160|uniprotkb:O75926|uniprotkb:Q96G19|uniprotkb:Q9UN16|intact:EBI-28970184|ensembl:ENSP00000262971	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:pias4_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein gamma(gene name synonym)|uniprotkb:PIASy(gene name synonym)|uniprotkb:PIAS4(gene name)|psi-mi:PIAS4(display_short)|uniprotkb:PIASG(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS4(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Zhang et al. (2004)	pubmed:15251447|mint:MINT-5217111	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7275870|mint:MINT-50624	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105229(gene)|ensembl:ENST00000262971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|ensembl:ENSP00000262971|refseq:NP_056981.2|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990234"(transferase complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027224|interpro:IPR036361|interpro:IPR038654|reactome:R-HSA-196791|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|dip:DIP-32499N|mint:MINT-1202940(identity)	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168|mint:MINT-1202946(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F5|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2004/12/02	2014/10/16	rogid:/1DLDSbuYFdXVUmENWJvNI7WqcQ9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:70FBBF8328EFD95D|rigid:PUpbI9EaEq2cdPJmUxZTLwR2FDY	true	tag:?-?(MINT-1202941)	tag:?-?(MINT-1202947)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P06241	uniprotkb:P22681	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (1998)	pubmed:9677430|mint:MINT-6548030	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8678230|mint:MINT-50666	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439|mint:MINT-1536885(identity)	refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377|mint:MINT-1536881(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F5|comment:homomint|comment:domino|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/12/04	2014/10/16	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	intact-crc:43C0C3C1CC40AB85|rigid:B5lPxxH6KgwPl/duLkrUhnFwcCY	true	binding-associated region:81-245(IPR000980)|glutathione s tranferase tag:?-?(MINT-8197180)	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06729	uniprotkb:P06241	intact:EBI-3912464|uniprotkb:Q96TE5|ensembl:ENSP00000358490	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:cd2_human(display_long)|uniprotkb:CD2(gene name)|psi-mi:CD2(display_short)|uniprotkb:SRBC(gene name synonym)|uniprotkb:Erythrocyte receptor(gene name synonym)|uniprotkb:LFA-2(gene name synonym)|uniprotkb:LFA-3 receptor(gene name synonym)|uniprotkb:Rosette receptor(gene name synonym)|uniprotkb:T-cell surface antigen T11/Leu-5(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (1998)	pubmed:9677430|mint:MINT-6548030	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8678205|mint:MINT-50665	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001758.2|ensembl:ENST00000369478(transcript)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030887"(positive regulation of myeloid dendritic cell activation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015632(CD2)|interpro:IPR036179|mint:P06729|rcsb pdb:1CDB|rcsb pdb:1GYA|rcsb pdb:1HNF|rcsb pdb:1L2Z|rcsb pdb:1QA9|rcsb pdb:2J6O|rcsb pdb:2J7I|reactome:R-HSA-202733|ensembl:ENSG00000116824(gene)|refseq:NP_001315538.1|mint:MINT-1536862(identity)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439|mint:MINT-1536866(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F5|comment:homomint|comment:domino|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/12/04	2014/10/16	rogid:GN7E4kazkOZr2RuMuSMu5WGrbsE9606	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:A0295797748EFCC6|rigid:LyyzZL5Qg/aClHq/DZjHdTSQXfY	true	-	glutathione s tranferase tag:?-?(MINT-1536871)|binding-associated region:81-245(IPR000980)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P16333	uniprotkb:Q7L0Q8	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Shutes et al. (2004)	pubmed:15556869|mint:MINT-5217345	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7394194|mint:MINT-50689	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|mint:MINT-1211145(identity)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420|mint:MINT-1211137(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F4D|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2004/12/06	2014/10/16	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	intact-crc:48A3966DAC6899FB|rigid:opveKcnvlDlAQbznNH0KP0AIf6s	true	-	binding-associated region:1-47(MINT-1211138)|tag:?-?(MINT-1211140)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19174	uniprotkb:Q7L0Q8	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shutes et al. (2004)	pubmed:15556869|mint:MINT-5217345	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7394281|mint:MINT-50690	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|mint:MINT-1211179(identity)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420|mint:MINT-1211173(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F4D|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2004/12/06	2014/10/16	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	intact-crc:016F83A6904A2386|rigid:Ygcuigwr+Ad+au7PBlGwb6oAnkw	true	-	tag:?-?(MINT-1211174)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04050	uniprotkb:P38827	intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym)	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:"MI:0045"(experimental interaction detection)	Ng et al. (2003)	pubmed:12667453|mint:MINT-5216296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8629754|mint:MINT-50763	intact-miscore:0.22	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-732089(identity)	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827|mint:MINT-732083(identity)	-	crc64:A45C1360FF99F968|comment:"Stoichiometry: 1.0"	crc64:B7FA5D60F71063FD|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:homomint|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/13	2014/10/16	rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	intact-crc:F7D0465CBF2D1A34|rigid:nmmqwculhs0Zg7uig5TaUnnMZ2I	true	O-phospho-L-serine:2-2(MINT-732090)	tag:?-?(MINT-732084)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38827	uniprotkb:P32585	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Ng et al. (2003)	pubmed:12667453|mint:MINT-5216296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8629773|mint:MINT-50764	intact-miscore:0.22	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827|mint:MINT-732069(identity)	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585|mint:MINT-732075(identity)	-	crc64:B7FA5D60F71063FD|comment:"Stoichiometry: 1.0"	crc64:B1148FC187C2802A|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/13	2014/10/16	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	intact-crc:6D5BC70A5EC23AD8|rigid:6W/rQ6YsZNnu2fY1esplNPq3Xak	true	tag:?-?(MINT-732070)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9P0K1	uniprotkb:Q9NYB9	intact:EBI-1567236|uniprotkb:O75075|uniprotkb:O75076|uniprotkb:Q9P0K2|uniprotkb:Q9UIA1|uniprotkb:Q9UKK2|ensembl:ENSP00000265727	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	psi-mi:ada22_human(display_long)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2(gene name synonym)|uniprotkb:Metalloproteinase-disintegrin ADAM22-3(gene name synonym)|uniprotkb:ADAM22(gene name)|psi-mi:ADAM22(display_short)|uniprotkb:MDC2(gene name synonym)	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567753|mint:MINT-51035	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR034027|interpro:IPR036436|rcsb pdb:3G5C|rcsb pdb:5Y2Z|rcsb pdb:5Y31|rcsb pdb:7CQF|reactome:R-HSA-5682910|ensembl:ENSG00000008277(gene)|ensembl:ENST00000265727(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018358|interpro:IPR024079|refseq:NP_004185.1|refseq:NP_068367.1|refseq:NP_068368.2|refseq:NP_068369.1|mint:MINT-724725(identity)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724719(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:pEM4mE6AUDeeGEhYogJDkrL2/jU9606	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	intact-crc:0F25FCDFD23B4AD2|rigid:RID1mBn0S5FZaXibyd6Ix0wjCtQ	true	tag:?-?(MINT-724726)	tag:?-?(MINT-724720)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9NYB9	uniprotkb:Q61072	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	intact:EBI-77983|uniprotkb:E9QPP2|ensembl:ENSMUSP00000081048|uniprotkb:Q60618|uniprotkb:Q61853|uniprotkb:Q80U94	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:adam9_mouse(display_long)|uniprotkb:Adam9(gene name)|psi-mi:Adam9(display_short)|uniprotkb:Kiaa0021(gene name synonym)|uniprotkb:Mdc9(gene name synonym)|uniprotkb:Mltng(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567827|mint:MINT-51037	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724758(identity)	ensembl:ENSMUSG00000031555(gene)|ensembl:ENSMUST00000084035(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_031430.2|mint:MINT-724764(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	rogid:GSTKev8sg5lfwupVNEpPkPhFxHA10090	intact-crc:518D3FE369272047|rigid:Yt1gWK6v+3YIkyhnD5BhqUlvPXk	true	tag:?-?(MINT-724759)	tag:?-?(MINT-724765)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9UKF5	uniprotkb:Q9NYB9	intact:EBI-8567781|ensembl:ENSP00000352177|ensembl:ENSP00000384229|ensembl:ENSP00000414544|ensembl:ENSP00000423517|ensembl:ENSP00000478469|ensembl:ENSP00000484862|uniprotkb:Q9UHP1|intact:MINT-252736|uniprotkb:Q4W5F3|uniprotkb:Q9UKF3|uniprotkb:Q9UKF4	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	psi-mi:ada29_human(display_long)|uniprotkb:ADAM29(gene name)|psi-mi:ADAM29(display_short)|uniprotkb:Cancer/testis antigen 73(gene name synonym)	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567774|mint:MINT-51036	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168594(gene)|ensembl:ENST00000359240(transcript)|ensembl:ENST00000404450(transcript)|ensembl:ENST00000445694(transcript)|ensembl:ENST00000514159(transcript)|ensembl:ENST00000615367(transcript)|ensembl:ENST00000618444(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:XP_011529859.1|refseq:XP_011529861.1|refseq:XP_011529862.1|refseq:XP_011529863.1|refseq:XP_011529858.1|ensembl:ENSP00000352177|ensembl:ENSP00000384229|ensembl:ENSP00000414544|ensembl:ENSP00000423517|ensembl:ENSP00000478469|ensembl:ENSP00000484862|refseq:NP_001124177.1|refseq:NP_055084.3|refseq:NP_001124176.1|refseq:NP_001124175.1|refseq:NP_001265054.1|refseq:NP_001265055.1|refseq:NP_001265056.1|mint:MINT-724694(identity)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724688(identity)	-	comment:mint|function:May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:19E77bw/6KqbspfB+MLuo+4ZQnM9606	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	intact-crc:109AA99D6D87AF49|rigid:NKWDwrP0mhbrm62wENQhLTgbDP4	true	tag:?-?(MINT-724695)	tag:?-?(MINT-724689)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:P04049	uniprotkb:P05783	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Ku et al. (2004)	pubmed:15314064|mint:MINT-5217163	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7291077|mint:MINT-51055	intact-miscore:0.22	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N|mint:MINT-1204765(identity)	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N|mint:MINT-1204769(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1C|negative:the interactions are not observed under these experimental conditions|comment:experimental=overlay assay|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/01/05	2014/10/16	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:A1D392EF806C301E|rigid:chf0fHmVexFHq061l2z7laUOvR8	true	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LW7	uniprotkb:O95999	intact:EBI-7443927|intact:MINT-1215062|uniprotkb:Q5BJH8|uniprotkb:Q9BSY2|ensembl:ENSP00000437237	intact:EBI-958922|ensembl:ENSP00000498104|uniprotkb:Q5VUF1	psi-mi:car19_human(display_long)|uniprotkb:C9orf89(gene name synonym)|uniprotkb:CARD19(gene name)|psi-mi:CARD19(display_short)|uniprotkb:Bcl10-interacting CARD protein(gene name synonym)	psi-mi:bcl10_human(display_long)|uniprotkb:BCL10(gene name)|psi-mi:BCL10(display_short)|uniprotkb:CIPER(gene name synonym)|uniprotkb:CLAP(gene name synonym)|uniprotkb:Cellular homolog of vCARMEN(gene name synonym)|uniprotkb:Mammalian CARD-containing adapter molecule E10(gene name synonym)|uniprotkb:Cellular-E10(gene name synonym)|uniprotkb:CARD-like apoptotic protein(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 10(gene name synonym)|uniprotkb:CED-3/ICH-1 prodomain homologous E10-like regulator(gene name synonym)|uniprotkb:CARD-containing molecule enhancing NF-kappa-B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Woo et al. (2004)	pubmed:15637807|mint:MINT-5217449|imex:IM-24231	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7444014|mint:MINT-51113	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115686.3|ensembl:ENSG00000165233(gene)|ensembl:ENST00000466409(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050700"(CARD domain binding)|interpro:IPR011029(DEATH-like)|interpro:IPR042146|interpro:IPR043574|rcsb pdb:4DWN|rcsb pdb:4FH0|mint:MINT-1215104(identity)	ensembl:ENSG00000142867(gene)|ensembl:ENST00000648566(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032094"(response to food)|go:"GO:0032449"(CBM complex)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR033238|interpro:IPR042143|mint:O95999|rcsb pdb:2MB9|rcsb pdb:6BZE|rcsb pdb:6GK2|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866654|refseq:NP_003912.1|dip:DIP-29740N|mint:MINT-1215110(identity)	-	comment:mint|function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3C|comment:mutation L65A of BinCARD abolished its ability to bind to Bcl10|comment:homomint|comment:mint|negative:true|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/01/13	2014/10/16	rogid:CJyuiBC7Pz0Zw/Vrae4bgZNgXKM9606	rogid:BUrlS8JdWGi4LWWgp0FfpILCeDY9606	intact-crc:0FDA3CCD55035026|rigid:/FQYnLtZDO4EVVk30FUXnySGuSg	true	mutation disrupting interaction:65-65(MINT-1215105)	tag:?-?(MINT-1215111)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62834	uniprotkb:Q9Z0S9	intact:EBI-491414|uniprotkb:P10113|ensembl:ENSP00000348786|ensembl:ENSP00000358723|intact:EBI-1047696	intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4	psi-mi:rap1a_human(display_long)|uniprotkb:GTP-binding protein smg p21A(gene name synonym)|uniprotkb:Ras-related protein Krev-1(gene name synonym)|uniprotkb:C21KG(gene name synonym)|uniprotkb:G-22K(gene name synonym)|uniprotkb:RAP1A(gene name)|psi-mi:RAP1A(display_short)|uniprotkb:KREV1(gene name synonym)	psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Figueroa et al. (2001)	pubmed:11335720|imex:IM-26228	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-492194	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0097421"(liver regeneration)|refseq:NP_001278825.1|refseq:NP_001010935.1|refseq:NP_002875.1|go:"GO:0035579"(specific granule membrane)|go:"GO:0035690"|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|ensembl:ENSG00000116473(gene)|ensembl:ENST00000356415(transcript)|ensembl:ENST00000369709(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010008"(endosome membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0030054"(cell junction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|rcsb pdb:1C1Y|rcsb pdb:1GUA|rcsb pdb:3KUC|rcsb pdb:4KVG|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8875555|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:XP_016857451.1|refseq:XP_016857452.1|refseq:XP_016857453.1|dip:DIP-29106N	ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1	-	-	-	negative:The interaction does not occur under these experimental conditions.|comment:The mutation from gly-val makes the GTP-bound Ras mutant constitutively active. GTP required for activity.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/01/26	2014/10/16	rogid:QtjMjJiMQF0CbTD40IZgca4XfIU9606	rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090	intact-crc:7A16FADA0C3B14A4|rigid:6vR/5LLWoYkGbxY32sJq1af6CBQ	true	mutation:12-12	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40450	uniprotkb:P41832	intact:EBI-3711|uniprotkb:D6VVC7|ensemblfungi:YIL159W	intact:EBI-3692|uniprotkb:O13450|uniprotkb:D6W0S3|ensemblfungi:YNL271C	psi-mi:bnr1_yeast(display_long)|uniprotkb:YIL159W(locus name)|uniprotkb:BNR1(gene name)|psi-mi:BNR1(display_short)	psi-mi:bni1_yeast(display_long)|uniprotkb:PPF3(gene name synonym)|uniprotkb:SHE5(gene name synonym)|uniprotkb:BNI1(gene name)|psi-mi:BNI1(display_short)|uniprotkb:YNL271C(locus name)|uniprotkb:N0646(orf name)|uniprotkb:Synthetic lethal 39(gene name synonym)|uniprotkb:Sensitive to high expression protein 5(gene name synonym)|uniprotkb:Pointed projection formation protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nelson et al. (2004)	pubmed:15020407|mint:MINT-5216964	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7155026|mint:MINT-56580	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012107.1|sgd:S000001421|dip:DIP-817N|mint:P40450|ensemblfungi:YIL159W(gene)|ensemblfungi:YIL159W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032153"(cell division site)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:MINT-1174245(identity)	refseq:NP_014128.2|sgd:S000005215|dip:DIP-974N|ensemblfungi:YNL271C(gene)|ensemblfungi:YNL271C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|rcsb pdb:1UX4|rcsb pdb:1UX5|rcsb pdb:1Y64|mint:MINT-1174237(identity)	-	crc64:B16B04A33C9D2F08|comment:"Stoichiometry: 1.0"	crc64:0C5A9D5280A5858F|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F6A|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/03/08	2014/10/16	rogid:GRc2bFQ73EHo4jkkcL4H8m9Sdu8559292	rogid:aS6XG+rT9RfN7DLRaqtiNywyVro559292	intact-crc:A4C04F62EE4548C6|rigid:7aJ4fBSD8XUUHfjWgXRs0zMRcaI	true	tag:?-?(MINT-1174246)	tag:?-?(MINT-1174240)|binding-associated region:1227-1397(MINT-1174238)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23201	uniprotkb:P41832	intact:EBI-17803|uniprotkb:D6VXY3|ensemblfungi:YLL021W	intact:EBI-3692|uniprotkb:O13450|uniprotkb:D6W0S3|ensemblfungi:YNL271C	psi-mi:spa2_yeast(display_long)|uniprotkb:SPA2(gene name)|psi-mi:SPA2(display_short)|uniprotkb:PEA1(gene name synonym)|uniprotkb:YLL021W(locus name)|uniprotkb:L1209(orf name)	psi-mi:bni1_yeast(display_long)|uniprotkb:PPF3(gene name synonym)|uniprotkb:SHE5(gene name synonym)|uniprotkb:BNI1(gene name)|psi-mi:BNI1(display_short)|uniprotkb:YNL271C(locus name)|uniprotkb:N0646(orf name)|uniprotkb:Synthetic lethal 39(gene name synonym)|uniprotkb:Sensitive to high expression protein 5(gene name synonym)|uniprotkb:Pointed projection formation protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nelson et al. (2004)	pubmed:15020407|mint:MINT-5216964	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7154989|mint:MINT-56579	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013079.1|sgd:S000003944|ensemblfungi:YLL021W(gene)|ensemblfungi:YLL021W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031382"(mating projection formation)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0031385"(regulation of termination of mating projection growth)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0043332"(mating projection tip)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR039892|mint:P23201|dip:DIP-99N|mint:MINT-1174308(identity)	refseq:NP_014128.2|sgd:S000005215|dip:DIP-974N|ensemblfungi:YNL271C(gene)|ensemblfungi:YNL271C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|rcsb pdb:1UX4|rcsb pdb:1UX5|rcsb pdb:1Y64|mint:MINT-1174300(identity)	-	crc64:2EBB616152382C89|comment:"Stoichiometry: 1.0"	crc64:0C5A9D5280A5858F|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F6A|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/03/08	2014/10/16	rogid:oRildAaA55yGWhSLQ9Zn3Wfndkg559292	rogid:aS6XG+rT9RfN7DLRaqtiNywyVro559292	intact-crc:0FFDD6BDA8E99E5E|rigid:OnIDtRWB4yUVkioY4k1lZp7+wA0	true	tag:?-?(MINT-1174309)	tag:?-?(MINT-1174303)|binding-associated region:1227-1397(MINT-1174301)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y5B0	uniprotkb:Q99873	intact:EBI-2807555|ensembl:ENSP00000484525|uniprotkb:Q9Y6F5|uniprotkb:Q7Z644|uniprotkb:Q96BZ1|uniprotkb:A8MY97	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:ctdp1_human(display_long)|uniprotkb:CTDP1(gene name)|psi-mi:CTDP1(display_short)|uniprotkb:FCP1(gene name synonym)|uniprotkb:TFIIF-associating CTD phosphatase(gene name synonym)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Amente et al. (2005)	pubmed:15670829|imex:IM-14128|mint:MINT-5217489	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7465439|mint:MINT-56505|imex:IM-14128-12	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000060069(gene)|ensembl:ENST00000613122(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0030496"(midbody)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR001357(BRCT)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011947(FCP1-like phosphatase, phosphatase domain)|interpro:IPR015388(FCP1-like phosphatase, C-terminal)|interpro:IPR023214|interpro:IPR036412|interpro:IPR036420|interpro:IPR039189|rcsb pdb:1J2X|rcsb pdb:1ONV|rcsb pdb:2K7L|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_001189433.1|refseq:NP_004706.3|refseq:NP_430255.2|dip:DIP-41788N|mint:MINT-1216990(identity)	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N|mint:MINT-1216994(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/03/08	2018/04/06	rogid:LEqMeYJjhIWOx3RZtX3ljR5IZS49606	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	intact-crc:4ED4CEAC56D6BA68|rigid:/a5JhTyrwMG4NsKWr3cwukCP6Yo	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P39743	uniprotkb:P39940	intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Stamenova et al. (2004)	pubmed:14761940|mint:MINT-5216900	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7127692|mint:MINT-56595	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N|mint:MINT-1171900(identity)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940|mint:MINT-1171891(identity)	-	crc64:3F0AB53EBCC95A5B|comment:"Stoichiometry: 1.0"	crc64:6F1836384479E70F|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F2A F2B|comment:domino|comment:mint|negative:true	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/03/11	2014/10/16	rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:19480DC30A1DB13F|rigid:94vWqHnfe5f4tNbfdfh33SBBPdY	true	binding-associated region:428-482(MINT-1171901)|tag:?-?(MINT-1171904)	tag:?-?(MINT-1171895)|binding-associated region:228-432(MINT-1171892)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52734	uniprotkb:Q60598	intact:EBI-6992536|ensembl:ENSMUSP00000026296|uniprotkb:Q921L2|intact:MINT-272222	intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368	psi-mi:fgd1_mouse(display_long)|uniprotkb:Fgd1(gene name)|psi-mi:Fgd1(display_short)|uniprotkb:Faciogenital dysplasia 1 protein homolog(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)	psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Hou et al. (2003)	pubmed:12913069|mint:MINT-5216617	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-6992755|mint:MINT-56708	intact-miscore:0.27	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025265(gene)|ensembl:ENSMUST00000026296(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-9013148|refseq:NP_032027.2|mint:MINT-738438(identity)	refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N|mint:MINT-738447(identity)	-	comment:mint|function:Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F6|comment:homomint|comment:mint|negative:true	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/03/22	2014/10/16	rogid:+moi9C3+tDgW7Y10QH4sGNqpr8w10090	rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090	intact-crc:F69489CE7C7973F4|rigid:5z7caAYZ1t5YtH+6WqM//jyCy+4	true	tag:?-?(MINT-738441)|binding-associated region:?-?(MINT-738439)	tag:?-?(MINT-738448)	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:P27986	uniprotkb:P43405	intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19	intact:EBI-78302|ensembl:ENSP00000364898|ensembl:ENSP00000364907	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	psi-mi:ksyk_human(display_long)|uniprotkb:SYK(gene name)|psi-mi:SYK(display_short)|uniprotkb:Spleen tyrosine kinase(gene name synonym)|uniprotkb:p72-Syk(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moon et al. (2005)	pubmed:15536084|mint:MINT-5217304	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375558|mint:MINT-56736	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N|mint:MINT-1210135(identity)	refseq:NP_001128524.1|refseq:NP_001167638.1|refseq:NP_001167639.1|refseq:NP_003168.2|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043313"(regulation of neutrophil degranulation)|go:"GO:0043366"(beta selection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071226"(cellular response to molecule of fungal origin)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090237"(regulation of arachidonic acid secretion)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990858"(cellular response to lectin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43405|rcsb pdb:1A81|rcsb pdb:1CSY|rcsb pdb:1CSZ|rcsb pdb:1XBA|rcsb pdb:1XBB|rcsb pdb:1XBC|rcsb pdb:3BUW|rcsb pdb:3EMG|rcsb pdb:3FQE|rcsb pdb:3FQH|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019815"(B cell receptor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032009"(early phagosome)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032752"(positive regulation of interleukin-3 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032928"(regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0016170"(interleukin-15 receptor binding)|rcsb pdb:3FQS|rcsb pdb:3SRV|rcsb pdb:3TUB|rcsb pdb:3TUC|rcsb pdb:3TUD|rcsb pdb:3VF8|rcsb pdb:3VF9|rcsb pdb:4DFL|rcsb pdb:4DFN|rcsb pdb:4F4P|rcsb pdb:4FL1|rcsb pdb:4FL2|rcsb pdb:4FL3|rcsb pdb:4FYN|rcsb pdb:4FYO|rcsb pdb:4FZ6|rcsb pdb:4FZ7|rcsb pdb:4GFG|rcsb pdb:4I0R|ensembl:ENSG00000165025(gene)|ensembl:ENST00000375746(transcript)|ensembl:ENST00000375754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|rcsb pdb:4I0S|rcsb pdb:4I0T|rcsb pdb:4PUZ|rcsb pdb:4PV0|rcsb pdb:4PX6|rcsb pdb:4RSS|rcsb pdb:4RX7|rcsb pdb:4RX8|rcsb pdb:4RX9|rcsb pdb:4WNM|rcsb pdb:4XG2|rcsb pdb:4XG3|rcsb pdb:5TIU|rcsb pdb:5TR6|rcsb pdb:5TT7|rcsb pdb:5Y5T|rcsb pdb:5Y5U|rcsb pdb:6HM6|rcsb pdb:6HM7|rcsb pdb:6SSB|rcsb pdb:6VOV|rcsb pdb:6ZC0|rcsb pdb:6ZCP|rcsb pdb:6ZCQ|rcsb pdb:6ZCR|rcsb pdb:6ZCS|rcsb pdb:6ZCU|rcsb pdb:6ZCX|rcsb pdb:6ZCY|rcsb pdb:4XG4|reactome:R-HSA-114604|reactome:R-HSA-2029481|reactome:R-HSA-2029482|rcsb pdb:4XG7|rcsb pdb:4XG8|rcsb pdb:4XG9|rcsb pdb:4YJO|rcsb pdb:4YJP|rcsb pdb:4YJQ|rcsb pdb:4YJR|rcsb pdb:4YJS|rcsb pdb:4YJT|rcsb pdb:4YJU|rcsb pdb:4YJV|rcsb pdb:5C26|rcsb pdb:5C27|rcsb pdb:5CXH|rcsb pdb:5CXZ|rcsb pdb:5CY3|rcsb pdb:5GHV|rcsb pdb:5LMA|rcsb pdb:4XG6|rcsb pdb:5LMB|rcsb pdb:5T68|refseq:XP_011517248.1|refseq:XP_005252204.1|reactome:R-HSA-2029485|reactome:R-HSA-2424491|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-5607764|reactome:R-HSA-5621480|reactome:R-HSA-9020558|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|reactome:R-HSA-983695|dip:DIP-253N|mint:MINT-1210126(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4A|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/03/24	2014/10/16	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	rogid:SAOtCMFKG07Wej573EklHjusYVA9606	intact-crc:58BCAE8539A84B2D|rigid:3qo+k/f+m/NZIP2GXhNuhlcFBQM	true	tag:?-?(MINT-1210139)|binding-associated region:439-724(MINT-1210136)	binding-associated region:370-629(MINT-1210127)|tag:?-?(MINT-1210130)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62158	uniprotkb:Q14318	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Weiwad et al. (2005)	pubmed:15757646|imex:IM-11432|mint:MINT-5217580	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7518108|mint:MINT-58244|imex:IM-11432-3	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-1339738(identity)	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N|mint:MINT-1339734(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|negative:the interactions are not observed under these experimental conditions|comment:This ineteraction does not occur in the precense nor absence of calcium|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line)	-	2005/04/06	2014/10/16	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:56BB882498097AAD|rigid:iEgiVqUFis1Zs2QG560Ibpg9a74	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62158	uniprotkb:Q14318	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Weiwad et al. (2005)	pubmed:15757646|imex:IM-11432|mint:MINT-5217580	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7518074|mint:MINT-58242|imex:IM-11432-4	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-1339751(identity)	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N|mint:MINT-1339747(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:The interaction does not occurs in the presence nor the absence of calcium|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line)	-	2005/04/06	2014/10/16	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:B31660CADD8FDE12|rigid:iEgiVqUFis1Zs2QG560Ibpg9a74	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96SB4	uniprotkb:O88453	intact:EBI-539478|uniprotkb:Q12890|uniprotkb:Q5R364|uniprotkb:Q5R365|uniprotkb:Q8IY12|uniprotkb:B4DS61|ensembl:ENSP00000362931	intact:EBI-539530	psi-mi:srpk1_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short)	psi-mi:safb1_rat(display_long)|uniprotkb:Safb(gene name)|psi-mi:Safb(display_short)|uniprotkb:Safb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nikolakaki et al. (2001)	pubmed:11509566	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-539583	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003128.3|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q96SB4|rcsb pdb:1WAK|rcsb pdb:1WBP|rcsb pdb:3BEG|rcsb pdb:4WUA|rcsb pdb:5MXX|rcsb pdb:5MY8|rcsb pdb:5NNG|rcsb pdb:5XV7|rcsb pdb:6FAD|rcsb pdb:7DD1|dip:DIP-33888N	rgd:620613|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR035979|interpro:IPR036361|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|reactome:R-RNO-3899300|mint:O88453|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034781	intact:EBI-539552(see-also)	-	-	caution:Residue numbering for SAFB1 as given in the paper - this is stated as being the C-terminal but sequence actually extends beyond 874 by a further 57 residues|negative:The interaction does not occur under these experimental conditions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/05/13	2014/10/16	rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606	rogid:SsTl3FJ/eux+ekMPUc64dv6IWq410116	intact-crc:B2AB83B466CAEECE|rigid:uUGqZ2ZqM+0TfucRFaLH/hkThRw	true	flag tag:?-?	binding-associated region:493-874|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96SB4	uniprotkb:O88453	intact:EBI-539478|uniprotkb:Q12890|uniprotkb:Q5R364|uniprotkb:Q5R365|uniprotkb:Q8IY12|uniprotkb:B4DS61|ensembl:ENSP00000362931	intact:EBI-539530	psi-mi:srpk1_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short)	psi-mi:safb1_rat(display_long)|uniprotkb:Safb(gene name)|psi-mi:Safb(display_short)|uniprotkb:Safb1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nikolakaki et al. (2001)	pubmed:11509566	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-539614	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003128.3|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q96SB4|rcsb pdb:1WAK|rcsb pdb:1WBP|rcsb pdb:3BEG|rcsb pdb:4WUA|rcsb pdb:5MXX|rcsb pdb:5MY8|rcsb pdb:5NNG|rcsb pdb:5XV7|rcsb pdb:6FAD|rcsb pdb:7DD1|dip:DIP-33888N	rgd:620613|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR035979|interpro:IPR036361|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|reactome:R-RNO-3899300|mint:O88453|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034781	intact:EBI-539601(see-also)	-	-	caution:Residue numbering for SAFB1 as given in the paper - this is stated as being the C-terminal but sequence actually extends beyond 874 by a further 57 residues|negative:The interaction does not occur under these experimental conditions	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/05/13	2014/10/16	rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606	rogid:SsTl3FJ/eux+ekMPUc64dv6IWq410116	intact-crc:98FFE49782B77277|rigid:uUGqZ2ZqM+0TfucRFaLH/hkThRw	true	flag tag:?-?	binding-associated region:493-874|tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38919	uniprotkb:P61326	intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2	intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8	psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym)	psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chan et al. (2004)	pubmed:14730019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-619211	intact-miscore:0.44	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N	ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N	-	-	-	negative:The interaction does not occur under these experimental conditions.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/14	2014/10/16	rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606	rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606	intact-crc:8D6EA6E924A88222|rigid:S4UMV84WcuTbHoFtIoIqJvcVl8M	true	glutathione s tranferase tag:n-n	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38919	uniprotkb:Q9Y5S9	intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2	intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265	psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym)	psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chan et al. (2004)	pubmed:14730019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-619211	intact-miscore:0.44	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N	refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957	-	-	-	negative:The interaction does not occur under these experimental conditions.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/14	2014/10/16	rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606	rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606	intact-crc:8D6EA6E924A88222|rigid:S4UMV84WcuTbHoFtIoIqJvcVl8M	true	glutathione s tranferase tag:n-n	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51813	uniprotkb:P11309-1	intact:EBI-696657|uniprotkb:A6NIH9|uniprotkb:O60564|uniprotkb:Q12871|ensembl:ENSP00000308774|ensembl:ENSP00000340082|ensembl:ENSP00000350224	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:bmx_human(display_long)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein(gene name synonym)|uniprotkb:Epithelial and endothelial tyrosine kinase(gene name synonym)|uniprotkb:NTK38(gene name synonym)|uniprotkb:BMX(gene name)|psi-mi:BMX(display_short)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xie et al. (2006)	imex:IM-14937|pubmed:16186805|mint:MINT-5217965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-783609	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001712.1|refseq:NP_975010.1|refseq:NP_001307795.1|ensembl:ENSG00000102010(gene)|ensembl:ENST00000342014(transcript)|ensembl:ENST00000348343(transcript)|ensembl:ENST00000357607(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR035875|interpro:IPR036860|rcsb pdb:2EKX|rcsb pdb:2YS2|rcsb pdb:3SXR|rcsb pdb:3SXS|rcsb pdb:6I99|reactome:R-HSA-111465|reactome:R-HSA-1660499	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	intact:EBI-696637(see-also)	-	isoform-comment:Initiates from CTG codon.	figure legend:4a|comment:"BMX associates with PIM1L (UniProt identifier /FTId=PRO_0000043349) but not the shorter isoform PIM1S, prodiced by alternative promoter usage (UniProt identifier /FTId=PRO_0000043350)."|caution:"Author also performs experiments (Fig. 4B) to demonstrate binding of SH3 domain of BMX (ETK) to PIM1L. However, BMX does not contain an SH3 domain and sequence co-ordinates are not given, so this information has not been added."|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2005/10/07	2018/10/22	rogid:vEWqPrMe5xCQRPeNReXM+8Djcjg9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	intact-crc:F1E0659338A2ADE6|rigid:hIBwPhnzLK6KvN8qNbaptji7F30	true	t7 tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11309-1	uniprotkb:P51813	intact:EBI-1018629|ensembl:ENSP00000362608	intact:EBI-696657|uniprotkb:A6NIH9|uniprotkb:O60564|uniprotkb:Q12871|ensembl:ENSP00000308774|ensembl:ENSP00000340082|ensembl:ENSP00000350224	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:bmx_human(display_long)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein(gene name synonym)|uniprotkb:Epithelial and endothelial tyrosine kinase(gene name synonym)|uniprotkb:NTK38(gene name synonym)|uniprotkb:BMX(gene name)|psi-mi:BMX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xie et al. (2006)	imex:IM-14937|pubmed:16186805|mint:MINT-5217965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-783639	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	refseq:NP_001712.1|refseq:NP_975010.1|refseq:NP_001307795.1|ensembl:ENSG00000102010(gene)|ensembl:ENST00000342014(transcript)|ensembl:ENST00000348343(transcript)|ensembl:ENST00000357607(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR035875|interpro:IPR036860|rcsb pdb:2EKX|rcsb pdb:2YS2|rcsb pdb:3SXR|rcsb pdb:3SXS|rcsb pdb:6I99|reactome:R-HSA-111465|reactome:R-HSA-1660499	intact:EBI-782980(see-also)	isoform-comment:Initiates from CTG codon.	-	figure legend:4a|comment:"BMX associates with PIM1L (UniProt identifier /FTId=PRO_0000043349) but not the shorter isoform PIM1S, prodiced by alternative promoter usage (UniProt identifier /FTId=PRO_0000043350)."|caution:"Author also performs experiments (Fig. 4B) to demonstrate binding of SH3 domain of BMX (ETK) to PIM1L. However, BMX does not contain an SH3 domain and sequence co-ordinates are not given, so this information has not been added."|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-22rv1)|taxid:9606(Homo sapiens)	-	2005/10/07	2018/10/22	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	rogid:vEWqPrMe5xCQRPeNReXM+8Djcjg9606	intact-crc:907A1534B7BD170B|rigid:hIBwPhnzLK6KvN8qNbaptji7F30	true	flag tag:n-n	t7 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11309-1	uniprotkb:P51813	intact:EBI-1018629|ensembl:ENSP00000362608	intact:EBI-696657|uniprotkb:A6NIH9|uniprotkb:O60564|uniprotkb:Q12871|ensembl:ENSP00000308774|ensembl:ENSP00000340082|ensembl:ENSP00000350224	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:bmx_human(display_long)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein(gene name synonym)|uniprotkb:Epithelial and endothelial tyrosine kinase(gene name synonym)|uniprotkb:NTK38(gene name synonym)|uniprotkb:BMX(gene name)|psi-mi:BMX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xie et al. (2006)	imex:IM-14937|pubmed:16186805|mint:MINT-5217965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-783652	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	refseq:NP_001712.1|refseq:NP_975010.1|refseq:NP_001307795.1|ensembl:ENSG00000102010(gene)|ensembl:ENST00000342014(transcript)|ensembl:ENST00000348343(transcript)|ensembl:ENST00000357607(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR035875|interpro:IPR036860|rcsb pdb:2EKX|rcsb pdb:2YS2|rcsb pdb:3SXR|rcsb pdb:3SXS|rcsb pdb:6I99|reactome:R-HSA-111465|reactome:R-HSA-1660499	intact:EBI-782988(see-also)	isoform-comment:Initiates from CTG codon.	-	figure legend:4a|comment:"BMX associates with PIM1L (UniProt identifier /FTId=PRO_0000043349) but not the shorter isoform PIM1S, prodiced by alternative promoter usage (UniProt identifier /FTId=PRO_0000043350)."|caution:"Author also performs experiments (Fig. 4B) to demonstrate binding of SH3 domain of BMX (ETK) to PIM1L. However, BMX does not contain an SH3 domain and sequence co-ordinates are not given, so this information has not been added."|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-22rv1)|taxid:9606(Homo sapiens)	-	2005/10/07	2018/10/22	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	rogid:vEWqPrMe5xCQRPeNReXM+8Djcjg9606	intact-crc:AFC6DF125B56AF2D|rigid:hIBwPhnzLK6KvN8qNbaptji7F30	true	flag tag:n-n	t7 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8C863	uniprotkb:O35732-2	intact:EBI-851782|uniprotkb:O54971|ensembl:ENSMUSP00000029126|ensembl:ENSMUSP00000105307	intact:EBI-851735|ensembl:ENSMUSP00000109948	psi-mi:itch_mouse(display_long)|uniprotkb:Itch(gene name)|psi-mi:Itch(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)	psi-mi:o35732-2(display_long)|uniprotkb:FLIP-S(isoform synonym)|uniprotkb:CASH beta(isoform synonym)|uniprotkb:Cflar(gene name)|psi-mi:Cflar(display_short)|uniprotkb:Cash(gene name synonym)|uniprotkb:Caspase homolog(gene name synonym)|uniprotkb:Caspase-eight-related protein(gene name synonym)|uniprotkb:Caspase-like apoptosis regulatory protein(gene name synonym)|uniprotkb:Cellular FLICE-like inhibitory protein(gene name synonym)|uniprotkb:FADD-like antiapoptotic molecule 1(gene name synonym)|uniprotkb:Inhibitor of FLICE(gene name synonym)|uniprotkb:MACH-related inducer of toxicity(gene name synonym)|uniprotkb:Usurpin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chang et al. (2006)	pubmed:16469705|imex:IM-11835	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852345	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230641.1|refseq:NP_032421.2|dip:DIP-29318N|go:"GO:0045087"(innate immune response)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090085"(regulation of protein deubiquitination)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:Q8C863|rcsb pdb:1YIU|rcsb pdb:2JO9|rcsb pdb:2JOC|rcsb pdb:5XMC|reactome:R-MMU-1253288|reactome:R-MMU-168638|reactome:R-MMU-2122948|reactome:R-MMU-5610780|reactome:R-MMU-5632684|reactome:R-MMU-8939236|reactome:R-MMU-983168|ensembl:ENSMUSG00000027598(gene)|ensembl:ENSMUST00000029126(transcript)|ensembl:ENSMUST00000109685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044389"(ubiquitin-like protein ligase binding)	intact:EBI-851716(cflar_mouse)|ensembl:ENSMUSG00000026031(gene)|ensembl:ENSMUST00000114309(transcript)	intact:EBI-851778(see-also)|imex:IM-1419(imex secondary)	-	-	negative:|isoform-comment:The short form of the cFLAR protein does not interact with ITCH.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/13	2017/10/30	rogid:gDN+qYu3L0C2MzekQFRAtVwgceE10090	rogid:xS+A3r2U8QXKzbKoRMveFlrbDzk10090	intact-crc:079E1768DD70D9EC|rigid:5i7J7nduD4w35HU+q/UAJNFsiUs	true	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86UW9	uniprotkb:Q9NRR5	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945714	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)	intact:EBI-956254(see-also)|intact:EBI-954830(see-also)|imex:IM-871(imex secondary)	-	-	negative:|figure legend:2 and table S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606	intact-crc:1041632DEC25509D|rigid:e5vzZwUQmOOHfypKPL3V8Hc1wcY	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N1L9	uniprotkb:P54253	intact:EBI-742695|uniprotkb:Q96EH4|uniprotkb:Q8NAF4|intact:EBI-945729|uniprotkb:Q8NAL8|ensembl:ENSP00000301887|uniprotkb:D9IC56	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	psi-mi:batf2_human(display_long)|uniprotkb:BATF2(gene name)|psi-mi:BATF2(display_short)|uniprotkb:Suppressor of AP-1 regulated by IFN(gene name synonym)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945723	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612465.3|refseq:NP_001287736.1|refseq:NP_001287737.1|ensembl:ENSG00000168062(gene)|ensembl:ENST00000301887(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029857|dip:DIP-48662N	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU	intact:EBI-955518(see-also)|imex:IM-1165(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:uL+kdibEI8CV/k5zjBeezZNzeAY9606	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:E2BD6B1C441F5A08|rigid:npxd37JA8QdFM6XExvxg21mUrP0	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54253	uniprotkb:Q86UW1	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	intact:EBI-945738|uniprotkb:Q6ZMC7|ensembl:ENSP00000296327	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:osta_human(display_long)|uniprotkb:SLC51A(gene name)|psi-mi:SLC51A(display_short)|uniprotkb:OSTA(gene name synonym)|uniprotkb:Solute carrier family 51 subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945743	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU	refseq:NP_689885.4|ensembl:ENSG00000163959(gene)|ensembl:ENST00000296327(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032782"(bile acid secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR005178(Protein of unknown function DUF300)	imex:IM-862(imex secondary)|intact:EBI-956870(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	rogid:EetsmPeag/cVP/OrTNDGRdlglX89606	intact-crc:30A9D6E0FD955D27|rigid:Un/kR5nLJfOfgKqcP2nM01Tkt34	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38432	uniprotkb:Q96HA8	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945762	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)	intact:EBI-955702(see-also)|imex:IM-811(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:7DD5E3DB1FFF425F|rigid:74Cv1NQhclaVx/zU0F+Rnt99EG0	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16594	uniprotkb:P38432	intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945773	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	imex:IM-696(imex secondary)|intact:EBI-955790(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:F9C30279F23A9735|rigid:tQLw782tpQhP4HZvyVlDdkirovo	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3Q8	uniprotkb:P04156	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-977302|ensembl:ENSP00000368752|ensembl:ENSP00000399376|ensembl:ENSP00000411599|ensembl:ENSP00000415284|uniprotkb:O60489|uniprotkb:P78446|uniprotkb:Q15216|uniprotkb:Q15221|uniprotkb:Q27H91|uniprotkb:Q8TBG0|uniprotkb:Q96E70|uniprotkb:Q9UP19|uniprotkb:Q5QPB4	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:prio_human(display_long)|uniprotkb:PrP27-30(gene name synonym)|uniprotkb:PrP33-35C(gene name synonym)|uniprotkb:ASCR(gene name synonym)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRIP(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:ALTPRP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945783	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035690"|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000171867(gene)|ensembl:ENST00000379440(transcript)|ensembl:ENST00000424424(transcript)|ensembl:ENST00000430350(transcript)|ensembl:ENST00000457586(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007049"(cell cycle)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009986"(cell surface)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016234"(inclusion body)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031648"(protein destabilization)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098794"(postsynapse)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:0045121"(membrane raft)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000817(Prion protein)|interpro:IPR022416|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR025860|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR036924|mint:P04156|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051087"(chaperone binding)|rcsb pdb:1E1G|rcsb pdb:1E1J|rcsb pdb:1E1P|rcsb pdb:1E1S|rcsb pdb:1E1U|rcsb pdb:1E1W|rcsb pdb:1FKC|rcsb pdb:1FO7|rcsb pdb:1H0L|rcsb pdb:1HJM|rcsb pdb:1HJN|rcsb pdb:1I4M|rcsb pdb:1OEH|rcsb pdb:1OEI|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1QLX|rcsb pdb:1QLZ|rcsb pdb:1QM0|rcsb pdb:1QM1|rcsb pdb:1QM2|rcsb pdb:1QM3|rcsb pdb:2IV4|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|rcsb pdb:2IV5|rcsb pdb:2IV6|rcsb pdb:2K1D|rcsb pdb:2KUN|rcsb pdb:2LBG|rcsb pdb:2LEJ|rcsb pdb:2LFT|rcsb pdb:2LSB|rcsb pdb:2LV1|rcsb pdb:2M8T|rcsb pdb:2OL9|rcsb pdb:2W9E|rcsb pdb:3HAF|rcsb pdb:3HAK|rcsb pdb:3HEQ|rcsb pdb:3HER|rcsb pdb:3HES|rcsb pdb:3HJ5|rcsb pdb:3HJX|rcsb pdb:3MD4|rcsb pdb:3MD5|rcsb pdb:3NHC|rcsb pdb:3NHD|rcsb pdb:3NVF|rcsb pdb:4DGI|rcsb pdb:4E1H|rcsb pdb:4E1I|rcsb pdb:4KML|rcsb pdb:4N9O|rcsb pdb:5L6R|rcsb pdb:5YJ4|rcsb pdb:5YJ5|rcsb pdb:6DU9|rcsb pdb:6LNI|rcsb pdb:6PQ5|rcsb pdb:6PQA|rcsb pdb:6SUZ|rcsb pdb:6SV2|rcsb pdb:6UUR|reactome:R-HSA-419037|reactome:R-HSA-9609523|refseq:NP_000302.1|refseq:NP_001073590.1|refseq:NP_001073591.1|refseq:NP_001073592.1|refseq:NP_898902.1|refseq:NP_001258490.1|dip:DIP-29933N	imex:IM-785(imex secondary)|intact:EBI-955894(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:O9dYBDKthE5DdgePny2xsDYzb989606	intact-crc:CDCA51059EBC7D1D|rigid:NLe4b816NUGE3/wEechrdk2SC8c	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15366	uniprotkb:Q96PU8	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945813	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	intact:EBI-955934(see-also)|imex:IM-747(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:4DC849FA2B15A878|rigid:MSi9jE67ZS23ejn6D0iFYA/vvLw	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60684	uniprotkb:Q16594	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945820	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N	imex:IM-760(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606	intact-crc:3E6D7AC8D038E478|rigid:ioQO68IGdD6MHhQfFBnYYoPdhjk	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRR5	uniprotkb:Q7Z3S9	intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym)	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945849	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9	intact:EBI-950278(see-also)|imex:IM-835(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	intact-crc:59ECFFA3FC10B68C|rigid:rWft3IwEeE/rXnsAgVGayw0hMdw	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96RK0	uniprotkb:Q9BYW2	intact:EBI-945857|uniprotkb:Q7LGI1|uniprotkb:Q9UEG5|uniprotkb:Q9Y6T1|ensembl:ENSP00000458663	intact:EBI-945869|uniprotkb:O75397|uniprotkb:O75405|uniprotkb:Q17RW8|uniprotkb:Q5BKS9|uniprotkb:Q5QGN2|uniprotkb:Q69YI5|uniprotkb:Q6IN64|uniprotkb:Q6ZN53|uniprotkb:Q6ZS25|uniprotkb:Q8N3R0|uniprotkb:Q8TCN0|uniprotkb:Q9C0D1|uniprotkb:Q9H696|uniprotkb:Q9NZW9|ensembl:ENSP00000386759	psi-mi:cic_human(display_long)|uniprotkb:CIC(gene name)|psi-mi:CIC(display_short)|uniprotkb:KIAA0306(gene name synonym)	psi-mi:setd2_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase SETD2(gene name synonym)|uniprotkb:KMT3A(gene name synonym)|uniprotkb:SET domain-containing protein 2(gene name synonym)|uniprotkb:Huntingtin-interacting protein B(gene name synonym)|uniprotkb:Huntingtin yeast partner B(gene name synonym)|uniprotkb:Huntingtin-interacting protein 1(gene name synonym)|uniprotkb:HIF-1(gene name synonym)|uniprotkb:p231HBP(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3A(gene name synonym)|uniprotkb:SETD2(gene name)|psi-mi:SETD2(display_short)|uniprotkb:HIF1(gene name synonym)|uniprotkb:HYPB(gene name synonym)|uniprotkb:KIAA1732(gene name synonym)|uniprotkb:SET2(gene name synonym)|uniprotkb:HSPC069(orf name)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945875	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055940.3|refseq:NP_001291744.1|ensembl:ENSP00000458663|dip:DIP-49964N|ensembl:ENSG00000079432(gene)|ensembl:ENST00000575354(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0035176"(social behavior)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q96RK0|rcsb pdb:2M41|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6JRP|rcsb pdb:6KZG|rcsb pdb:6KZH	refseq:NP_054878.5|ensembl:ENSG00000181555(gene)|ensembl:ENST00000409792(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0030900"(forebrain development)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048864"(stem cell development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060039"(pericardium development)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0060977"(coronary vasculature morphogenesis)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR013257(SRI, Set2 Rpb1 interacting)|interpro:IPR035441|interpro:IPR036020|interpro:IPR038190|interpro:IPR042294|interpro:IPR044437|mint:Q9BYW2|rcsb pdb:2A7O|rcsb pdb:2MDC|rcsb pdb:2MDI|rcsb pdb:2MDJ|rcsb pdb:4FMU|rcsb pdb:4H12|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5JLE|rcsb pdb:5LSS|rcsb pdb:5LSX|rcsb pdb:5LSY|rcsb pdb:5LSZ|rcsb pdb:5LT6|rcsb pdb:5LT7|rcsb pdb:5LT8|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:6J9J|rcsb pdb:6VDB|reactome:R-HSA-3214841	intact:EBI-952516(see-also)|imex:IM-1014(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:E3FWgv7mlzlumUUZ/Jke9JA+JeI9606	rogid:9f0NjyLj+lCSDh5yRP9lVMMepuw9606	intact-crc:417DE5602BE13565|rigid:oqM6hH1pqLT2PALCbRmDyDLlT3Y	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14103-4	uniprotkb:P63104	intact:EBI-432545|intact:EBI-8518738|intact:MINT-4853535|intact:EBI-8518799	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:q14103-4(display_long)|uniprotkb:p37(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	He et al. (2006)	pubmed:16902409|mint:MINT-5218944|imex:IM-10977	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1107667	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-299674(hnrpd_human)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	intact:EBI-1107640(see-also)	isoform-comment:Contains a omega-N-methylarginine at position 263. Contains a N6-acetyllysine at position 273.	-	figure legend:2B|isoform-comment:"AUF1 exists as four different isoforms (p37, p40, p42 and p45) that are generated by alternative splicing. p45 IsoformId:FQ14103-1. p42 IsoformId:FQ14103-2. Q14103-1. p40 IsoformId:FQ14103-3. p37 IsoformId:FQ14103-4.The p37 isoform of AUF1  Was used in the experiment."|isoform-comment:To date, seven 14-3-3  isoforms have been identified in human cells, all of which  share a high degree of amino-acid sequence conservation|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/31	2014/10/16	rogid:95oeXiQsI5XIjolCskx1RTkXh1M9606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	intact-crc:84F144A10D91EE8D|rigid:YdL8sm4OhRnWHPCs217hPu7wRsI	true	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P61981	uniprotkb:Q14103-4	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	intact:EBI-432545|intact:EBI-8518738|intact:MINT-4853535|intact:EBI-8518799	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q14103-4(display_long)|uniprotkb:p37(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	He et al. (2006)	pubmed:16902409|mint:MINT-5218944|imex:IM-10977	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1107699	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	intact:EBI-299674(hnrpd_human)	intact:EBI-1107735(see-also)	-	isoform-comment:Contains a omega-N-methylarginine at position 263. Contains a N6-acetyllysine at position 273.	figure legend:1C|isoform-comment:"AUF1 exists as four different isoforms (p37, p40, p42 and p45) that are generated by alternative splicing. p45 IsoformId:FQ14103-1. p42 IsoformId:FQ14103-2. Q14103-1. p40 IsoformId:FQ14103-3. p37 IsoformId:FQ14103-4.The p37 isoform of AUF1  Was used in the experiment."|isoform-comment:To date, seven 14-3-3  isoforms have been identified in human cells, all of which  share a high degree of amino-acid sequence conservation|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/31	2014/10/16	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rogid:95oeXiQsI5XIjolCskx1RTkXh1M9606	intact-crc:E9422FD906FAAEEE|rigid:9+uwZUt8ThIL1r9jxjO5/IdmD4w	true	-	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14103-2	uniprotkb:P31947	intact:EBI-432533|ensembl:ENSP00000305860|intact:EBI-8518682|intact:MINT-4853525	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	psi-mi:q14103-2(display_long)|uniprotkb:p42(isoform synonym)|uniprotkb:Dx4(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:"MI:0096"(pull down)	He et al. (2006)	pubmed:16902409|mint:MINT-5218944|imex:IM-10977	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1107711	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000352301(transcript)|intact:EBI-299674(hnrpd_human)|uniprotkb:Q14103-2(isoform-parent)	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N	intact:EBI-1024695(see-also)	-	-	figure legend:3B|isoform-comment:"AUF1 exists as four different isoforms (p37, p40, p42 and p45) that are generated by alternative splicing. p45 IsoformId:FQ14103-1. p42 IsoformId:FQ14103-2. Q14103-1. p40 IsoformId:FQ14103-3. p37 IsoformId:FQ14103-4."|isoform-comment:To date, seven 14-3-3  isoforms have been identified in human cells, all of which  share a high degree of amino-acid sequence conservation|comment:The predominant isoform of AUF1 which bound to 14-3-3sigma was the p37 protein, and to a much lesser extent p40 AUF1. There was no detectable interaction between 14-3-3sigma and the two larger AUF1 isoforms, p42 and p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/31	2014/10/16	rogid:MWJNPey2z9tE35qABuwCD762qKc9606	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	intact-crc:79E2D674F522E5DB|rigid:vxG6gm9sSwI/Mn4pR18zLdjObRs	true	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31947	uniprotkb:Q14103-1	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	intact:EBI-432527|ensembl:ENSP00000313199|intact:EBI-8518774|intact:MINT-4853520	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:q14103-1(display_long)|uniprotkb:p45(isoform synonym)|uniprotkb:Dx9(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	He et al. (2006)	pubmed:16902409|mint:MINT-5218944|imex:IM-10977	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1107724	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N	ensembl:ENST00000313899(transcript)|ensembl:ENSG00000138668(gene)|intact:EBI-299674(hnrpd_human)	intact:EBI-1024695(see-also)	-	-	figure legend:3B|isoform-comment:"AUF1 exists as four different isoforms (p37, p40, p42 and p45) that are generated by alternative splicing. p45 IsoformId:FQ14103-1. p42 IsoformId:FQ14103-2. Q14103-1. p40 IsoformId:FQ14103-3. p37 IsoformId:FQ14103-4."|isoform-comment:To date, seven 14-3-3  isoforms have been identified in human cells, all of which  share a high degree of amino-acid sequence conservation|comment:The predominant isoform of AUF1 which bound to 14-3-3sigma was the p37 protein, and to a much lesser extent p40 AUF1. There was no detectable interaction between 14-3-3sigma and the two larger AUF1 isoforms, p42 and p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/31	2014/10/16	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	intact-crc:047E94999A2ED5C5|rigid:9kNXHavj2V3o1uoLSINJXKT9zBc	true	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63104	uniprotkb:Q14103-4	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-432545|intact:EBI-8518738|intact:MINT-4853535|intact:EBI-8518799	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q14103-4(display_long)|uniprotkb:p37(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	He et al. (2006)	pubmed:16902409|mint:MINT-5218944|imex:IM-10977	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1107748	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	intact:EBI-299674(hnrpd_human)	intact:EBI-1107735(see-also)	-	isoform-comment:Contains a omega-N-methylarginine at position 263. Contains a N6-acetyllysine at position 273.	figure legend:1C|isoform-comment:"AUF1 exists as four different isoforms (p37, p40, p42 and p45) that are generated by alternative splicing. p45 IsoformId:FQ14103-1. p42 IsoformId:FQ14103-2. Q14103-1. p40 IsoformId:FQ14103-3. p37 IsoformId:FQ14103-4.The p37 isoform of AUF1  Was used in the experiment."|isoform-comment:To date, seven 14-3-3  isoforms have been identified in human cells, all of which  share a high degree of amino-acid sequence conservation|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/31	2014/10/16	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:95oeXiQsI5XIjolCskx1RTkXh1M9606	intact-crc:42F88911B8CF8ED5|rigid:YdL8sm4OhRnWHPCs217hPu7wRsI	true	-	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y738	uniprotkb:Q10173	intact:EBI-1002822|ensemblfungi:"SPBC409.04c.1:pep"	intact:EBI-1002565|ensemblfungi:"SPAC27F1.04c.1:pep"	psi-mi:mis12_schpo(display_long)|uniprotkb:NMS complex subunit mis12(gene name synonym)|uniprotkb:mis12(gene name)|psi-mi:mis12(display_short)|uniprotkb:SPBC409.04c(orf name)	psi-mi:nuf2_schpo(display_long)|uniprotkb:NMS complex subunit nuf2(gene name synonym)|uniprotkb:nuf2(gene name)|psi-mi:nuf2(display_short)|uniprotkb:SPAC27F1.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Asakawa et al. (2005)	pubmed:15728720	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1002954	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008685(Mis12)|refseq:NP_595454.1|rcsb pdb:5WWL|ensemblfungi:SPBC409.04c(gene)|ensemblfungi:SPBC409.04c.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0031617"(NMS complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)	refseq:NP_594532.1|ensemblfungi:SPAC27F1.04c(gene)|ensemblfungi:SPAC27F1.04c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0031617"(NMS complex)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0140456"(initial meiotic spindle pole body separation)|go:"GO:1990571"(meiotic centromere clustering)|interpro:IPR005549(Nuf2)|interpro:IPR038275|interpro:IPR041112|dip:DIP-36501N	-	-	crc64:D716FE83223BD16E	negative:The interaction does not occur under these experimental conditions.|figure legend:4E	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/08/31	2014/10/16	rogid:yrXBkZI35gLxR1J/zwm2Q0pbJco284812	rogid:9Tdy3w3GOZ05LitTxXrMLWRq/l0284812	intact-crc:C18542B4E7799547|rigid:tZYixeW1NMpm6DAp+qNO5mccpJI	true	tag:n-n	tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-1	uniprotkb:O60506	intact:EBI-432527|ensembl:ENSP00000313199|intact:EBI-8518774|intact:MINT-4853520	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:q14103-1(display_long)|uniprotkb:p45(isoform synonym)|uniprotkb:Dx9(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107790	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000313899(transcript)|ensembl:ENSG00000138668(gene)|intact:EBI-299674(hnrpd_human)	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	intact:EBI-1024824(see-also)	-	-	figure legend:1C|comment:NSAP-1 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	intact-crc:6C43C088F095B736|rigid:r8fpShDaJ3XNMZxf8PbQ5smESfI	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-2	uniprotkb:O60506	intact:EBI-432533|ensembl:ENSP00000305860|intact:EBI-8518682|intact:MINT-4853525	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:q14103-2(display_long)|uniprotkb:p42(isoform synonym)|uniprotkb:Dx4(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107801	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000352301(transcript)|intact:EBI-299674(hnrpd_human)|uniprotkb:Q14103-2(isoform-parent)	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	intact:EBI-1024824(see-also)	-	-	figure legend:1C|comment:NSAP-1 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:MWJNPey2z9tE35qABuwCD762qKc9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	intact-crc:F100DA9C7CF066D2|rigid:5IEAwhS66m3uM7ajaZYAuSGwvEo	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-1	uniprotkb:P67809	intact:EBI-432527|ensembl:ENSP00000313199|intact:EBI-8518774|intact:MINT-4853520	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626	psi-mi:q14103-1(display_long)|uniprotkb:p45(isoform synonym)|uniprotkb:Dx9(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107812	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000313899(transcript)|ensembl:ENSG00000138668(gene)|intact:EBI-299674(hnrpd_human)	refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)	intact:EBI-1024414(see-also)	-	-	figure legend:1C|comment:NSEP-1 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	intact-crc:7B971072967BF0F6|rigid:jW0cpe2ZkNocUGxhqgOkUddcemU	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P67809	uniprotkb:Q14103-2	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626	intact:EBI-432533|ensembl:ENSP00000305860|intact:EBI-8518682|intact:MINT-4853525	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:q14103-2(display_long)|uniprotkb:p42(isoform synonym)|uniprotkb:Dx4(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107823	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000352301(transcript)|intact:EBI-299674(hnrpd_human)|uniprotkb:Q14103-2(isoform-parent)	intact:EBI-1024414(see-also)	-	-	figure legend:1C|comment:NSEP-1 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	rogid:MWJNPey2z9tE35qABuwCD762qKc9606	intact-crc:E6D40A661A1E2112|rigid:XqXdLdfnhrNvzKBSkg8OarSwWv4	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-1	uniprotkb:Q9Y6M1	intact:EBI-432527|ensembl:ENSP00000313199|intact:EBI-8518774|intact:MINT-4853520	intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634	psi-mi:q14103-1(display_long)|uniprotkb:p45(isoform synonym)|uniprotkb:Dx9(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107834	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000313899(transcript)|ensembl:ENSG00000138668(gene)|intact:EBI-299674(hnrpd_human)	refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N	intact:EBI-1024562(see-also)	-	-	figure legend:1c|comment:IMP-2 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	rogid:k45UViReMAxCv2cu7+tx+auevQc9606	intact-crc:8D4698C9A91B7508|rigid:1NTsVtMfRMF5cMlaq1i4exsn5e8	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-2	uniprotkb:Q9Y6M1	intact:EBI-432533|ensembl:ENSP00000305860|intact:EBI-8518682|intact:MINT-4853525	intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634	psi-mi:q14103-2(display_long)|uniprotkb:p42(isoform synonym)|uniprotkb:Dx4(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107845	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000352301(transcript)|intact:EBI-299674(hnrpd_human)|uniprotkb:Q14103-2(isoform-parent)	refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N	intact:EBI-1024562(see-also)	-	-	figure legend:1c|comment:IMP-2 interacted only with AUF1p37 and p40 but not with p42 or p45.|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:MWJNPey2z9tE35qABuwCD762qKc9606	rogid:k45UViReMAxCv2cu7+tx+auevQc9606	intact-crc:52E3C7C9DC3A0C70|rigid:7LG/ifpo84dQJPv1WGi5xpt4qqg	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-4	uniprotkb:Q14103-1	intact:EBI-432545|intact:EBI-8518738|intact:MINT-4853535|intact:EBI-8518799	intact:EBI-432527|ensembl:ENSP00000313199|intact:EBI-8518774|intact:MINT-4853520	psi-mi:q14103-4(display_long)|uniprotkb:p37(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:q14103-1(display_long)|uniprotkb:p45(isoform synonym)|uniprotkb:Dx9(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107857	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-299674(hnrpd_human)	ensembl:ENST00000313899(transcript)|ensembl:ENSG00000138668(gene)|intact:EBI-299674(hnrpd_human)	intact:EBI-1107129(see-also)	isoform-comment:Contains a omega-N-methylarginine at position 263. Contains a N6-acetyllysine at position 273.	-	figure legend:1B|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:95oeXiQsI5XIjolCskx1RTkXh1M9606	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	intact-crc:87836A340BFE94B3|rigid:bdGjKNAgaDK0btS2O6zU205zp1s	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14103-4	uniprotkb:Q14103-2	intact:EBI-432545|intact:EBI-8518738|intact:MINT-4853535|intact:EBI-8518799	intact:EBI-432533|ensembl:ENSP00000305860|intact:EBI-8518682|intact:MINT-4853525	psi-mi:q14103-4(display_long)|uniprotkb:p37(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:q14103-2(display_long)|uniprotkb:p42(isoform synonym)|uniprotkb:Dx4(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Moraes et al. (2003)	pubmed:12674497	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107880	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-299674(hnrpd_human)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000352301(transcript)|intact:EBI-299674(hnrpd_human)|uniprotkb:Q14103-2(isoform-parent)	intact:EBI-1107129(see-also)	isoform-comment:Contains a omega-N-methylarginine at position 263. Contains a N6-acetyllysine at position 273.	-	figure legend:1B|negative:This experiment relates to a negative interaction|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/15	2014/10/16	rogid:95oeXiQsI5XIjolCskx1RTkXh1M9606	rogid:MWJNPey2z9tE35qABuwCD762qKc9606	intact-crc:559FBA340BFE94B3|rigid:Fh8eyT3fwt3PKwOiblTXmBi0zzk	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q40687	uniprotkb:Q0DJ33	intact:EBI-1100119|uniprotkb:Q7G5X0|ensemblplants:Os03t0669200-01|uniprotkb:A0A0P0W176|uniprotkb:F6M2M6|uniprotkb:Q0DPR1|uniprotkb:Q10FF8	intact:EBI-1100098|uniprotkb:Q2HNY6|uniprotkb:Q43604|ensemblplants:Os05t0333200-01|uniprotkb:P49083|uniprotkb:Q5KQF9|uniprotkb:Q5W732	psi-mi:gbb_orysj(display_long)|uniprotkb:RGB1(gene name)|psi-mi:RGB1(display_short)|uniprotkb:WD40 repeat-containing protein 80(gene name synonym)|uniprotkb:OSJNBa0039O18.9(orf name)|uniprotkb:LOC_Os03g46650(locus name)|uniprotkb:Os03g0669200(locus name)	psi-mi:gpa1_orysj(display_long)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:D1(gene name synonym)|uniprotkb:GA1(gene name synonym)|uniprotkb:RGA1(gene name synonym)|uniprotkb:OJ1005_D04.15(orf name)|uniprotkb:OSJNBa0049D13.1(orf name)|uniprotkb:Protein Dwarf1(gene name synonym)|uniprotkb:LOC_Os05g26890(locus name)|uniprotkb:Os05g0333200(locus name)|uniprotkb:Protein Daikoku dwarf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kato et al. (2004)	pubmed:15078334|imex:IM-19888	taxid:39947(orysj)|taxid:39947("Oryza sativa subsp. japonica (Rice)")	taxid:39947(orysj)|taxid:39947("Oryza sativa subsp. japonica (Rice)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1100306	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015631079.1|ensemblplants:Os03g0669200(gene)|ensemblplants:Os03t0669200-01(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009723"(response to ethylene)|go:"GO:0009845"(seed germination)|go:"GO:0009867"(jasmonic acid mediated signaling pathway)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010118"(stomatal movement)|go:"GO:0010154"(fruit development)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0048527"(lateral root development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1905392"(plant organ morphogenesis)|go:"GO:2000280"(regulation of root development)|interpro:IPR020472|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322	ensemblplants:Os05g0333200(gene)|ensemblplants:Os05t0333200-01(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0010476"(gibberellin mediated signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0005834"(heterotrimeric G-protein complex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002976(Plant G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|refseq:XP_015639183.1	intact:EBI-1100167(see-also)	-	-	figure legend:5a|comment:Both proteins were labelled with 35S-methionine and 35S-cysteine|negative:The interaction does not occur under these experimental  conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/27	2014/10/16	rogid:7kRuwBAzfTKAhZHFCgNVp/pfS9U39947	rogid:6UBQwzB2CnNfj796YvyBzCEdKYI39947	intact-crc:D2E8E2183886C5FE|rigid:fXBTnEbG+0v2eseBYC6XNjH7TC0	true	myc tag:?-?|35s radiolabel:?-?	ha tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q40687	uniprotkb:Q0DJ33	intact:EBI-1100119|uniprotkb:Q7G5X0|ensemblplants:Os03t0669200-01|uniprotkb:A0A0P0W176|uniprotkb:F6M2M6|uniprotkb:Q0DPR1|uniprotkb:Q10FF8	intact:EBI-1100098|uniprotkb:Q2HNY6|uniprotkb:Q43604|ensemblplants:Os05t0333200-01|uniprotkb:P49083|uniprotkb:Q5KQF9|uniprotkb:Q5W732	psi-mi:gbb_orysj(display_long)|uniprotkb:RGB1(gene name)|psi-mi:RGB1(display_short)|uniprotkb:WD40 repeat-containing protein 80(gene name synonym)|uniprotkb:OSJNBa0039O18.9(orf name)|uniprotkb:LOC_Os03g46650(locus name)|uniprotkb:Os03g0669200(locus name)	psi-mi:gpa1_orysj(display_long)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:D1(gene name synonym)|uniprotkb:GA1(gene name synonym)|uniprotkb:RGA1(gene name synonym)|uniprotkb:OJ1005_D04.15(orf name)|uniprotkb:OSJNBa0049D13.1(orf name)|uniprotkb:Protein Dwarf1(gene name synonym)|uniprotkb:LOC_Os05g26890(locus name)|uniprotkb:Os05g0333200(locus name)|uniprotkb:Protein Daikoku dwarf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kato et al. (2004)	pubmed:15078334|imex:IM-19888	taxid:39947(orysj)|taxid:39947("Oryza sativa subsp. japonica (Rice)")	taxid:39947(orysj)|taxid:39947("Oryza sativa subsp. japonica (Rice)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1100357	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015631079.1|ensemblplants:Os03g0669200(gene)|ensemblplants:Os03t0669200-01(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009723"(response to ethylene)|go:"GO:0009845"(seed germination)|go:"GO:0009867"(jasmonic acid mediated signaling pathway)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010118"(stomatal movement)|go:"GO:0010154"(fruit development)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0048527"(lateral root development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1905392"(plant organ morphogenesis)|go:"GO:2000280"(regulation of root development)|interpro:IPR020472|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322	ensemblplants:Os05g0333200(gene)|ensemblplants:Os05t0333200-01(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0010476"(gibberellin mediated signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0005834"(heterotrimeric G-protein complex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002976(Plant G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|refseq:XP_015639183.1	intact:EBI-1100167(see-also)	-	-	figure legend:5a|comment:Both proteins were labelled with 35S-methionine and 35S-cysteine|negative:The interaction does not occur under these experimental  conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/27	2014/10/16	rogid:7kRuwBAzfTKAhZHFCgNVp/pfS9U39947	rogid:6UBQwzB2CnNfj796YvyBzCEdKYI39947	intact-crc:9837FC9EE259CD34|rigid:fXBTnEbG+0v2eseBYC6XNjH7TC0	true	myc tag:?-?|35s radiolabel:?-?	ha tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13671-2	uniprotkb:P01112	intact:EBI-366034	intact:EBI-350145|uniprotkb:Q9BR65|uniprotkb:Q14080|uniprotkb:Q6FHV9|uniprotkb:B5BUA0|uniprotkb:Q9UCE2|ensembl:ENSP00000309845|ensembl:ENSP00000380723|ensembl:ENSP00000407586|ensembl:ENSP00000480686|ensembl:ENSP00000482366|ensembl:ENSP00000488757	psi-mi:q13671-2(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras inhibitor JC99(gene name synonym)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)	psi-mi:rash_human(display_long)|uniprotkb:HRAS(gene name)|psi-mi:HRAS(display_short)|uniprotkb:HRAS1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:p21ras(gene name synonym)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:Ha-Ras(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (1997)	pubmed:9144171|imex:IM-19895|mint:MINT-5221473	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102972	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-366017(rin1_human)	refseq:NP_001123914.1|refseq:NP_005334.1|refseq:NP_789765.1|ensembl:ENSG00000174775(gene)|ensembl:ENSG00000276536(gene)|ensembl:ENST00000311189(transcript)|ensembl:ENST00000397596(transcript)|ensembl:ENST00000451590(transcript)|ensembl:ENST00000610977(transcript)|ensembl:ENST00000615062(transcript)|ensembl:ENST00000631404(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01112|rcsb pdb:121P|rcsb pdb:1AA9|rcsb pdb:1AGP|rcsb pdb:1BKD|rcsb pdb:1CLU|rcsb pdb:1CRP|rcsb pdb:1CRQ|rcsb pdb:1CRR|rcsb pdb:1CTQ|rcsb pdb:1GNP|rcsb pdb:1GNQ|rcsb pdb:1GNR|rcsb pdb:1HE8|rcsb pdb:1IAQ|rcsb pdb:1IOZ|rcsb pdb:1JAH|rcsb pdb:1JAI|rcsb pdb:1K8R|rcsb pdb:1LF0|rcsb pdb:1LF5|rcsb pdb:1LFD|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1P2S|rcsb pdb:1P2T|rcsb pdb:1P2U|rcsb pdb:1P2V|rcsb pdb:1PLJ|rcsb pdb:1PLK|rcsb pdb:1PLL|rcsb pdb:1Q21|rcsb pdb:1QRA|rcsb pdb:1RVD|rcsb pdb:1WQ1|rcsb pdb:1XCM|rcsb pdb:1XD2|rcsb pdb:1XJ0|rcsb pdb:1ZVQ|rcsb pdb:1ZW6|rcsb pdb:221P|rcsb pdb:2C5L|rcsb pdb:2CE2|rcsb pdb:2CL0|rcsb pdb:2CL6|rcsb pdb:2CL7|rcsb pdb:2CLC|rcsb pdb:2CLD|rcsb pdb:2EVW|rcsb pdb:2GDP|rcsb pdb:2LCF|rcsb pdb:2LWI|rcsb pdb:2N42|rcsb pdb:2N46|rcsb pdb:2Q21|rcsb pdb:2QUZ|rcsb pdb:2RGA|rcsb pdb:2RGB|rcsb pdb:2RGC|rcsb pdb:2RGD|rcsb pdb:2RGE|rcsb pdb:2RGG|rcsb pdb:2UZI|rcsb pdb:2VH5|rcsb pdb:2X1V|rcsb pdb:3DDC|rcsb pdb:3I3S|rcsb pdb:3K8Y|rcsb pdb:3K9L|rcsb pdb:3K9N|rcsb pdb:3KKM|rcsb pdb:3KKN|rcsb pdb:3KUD|rcsb pdb:3L8Y|rcsb pdb:3L8Z|rcsb pdb:3LBH|rcsb pdb:3LBI|rcsb pdb:3LBN|rcsb pdb:3LO5|rcsb pdb:3OIU|rcsb pdb:3OIV|rcsb pdb:3OIW|rcsb pdb:3RRY|rcsb pdb:3RRZ|rcsb pdb:3RS0|rcsb pdb:3RS2|rcsb pdb:3RS3|rcsb pdb:3RS4|rcsb pdb:3RS5|rcsb pdb:3RS7|rcsb pdb:3RSL|rcsb pdb:3RSO|rcsb pdb:3TGP|rcsb pdb:421P|rcsb pdb:4DLR|rcsb pdb:4DLS|rcsb pdb:4DLT|rcsb pdb:4DLU|rcsb pdb:4DLV|rcsb pdb:4DLW|rcsb pdb:4DLX|rcsb pdb:4DLY|rcsb pdb:4DLZ|rcsb pdb:4DST|rcsb pdb:4DSU|rcsb pdb:4EFL|rcsb pdb:4EFM|rcsb pdb:4EFN|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4K81|rcsb pdb:4L9S|rcsb pdb:4L9W|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4Q21|rcsb pdb:4RSG|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:4XVQ|rcsb pdb:4XVR|rcsb pdb:521P|rcsb pdb:5B2Z|rcsb pdb:5B30|rcsb pdb:5E95|rcsb pdb:5P21|rcsb pdb:5VBE|rcsb pdb:5VBZ|rcsb pdb:5WDO|rcsb pdb:5WDP|rcsb pdb:5WDQ|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-3928662|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6Q21|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:5WPL|rcsb pdb:5X9S|rcsb pdb:5ZC6|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:621P|rcsb pdb:6AMB|rcsb pdb:6AXG|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D55|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6DZH|rcsb pdb:6E6C|rcsb pdb:6E6P|rcsb pdb:6MQT|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6ZJ0|rcsb pdb:6ZL3|rcsb pdb:721P|rcsb pdb:7JHP|rcsb pdb:7L0F|rcsb pdb:7L0G|rcsb pdb:821P|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|refseq:NP_001304983.1|dip:DIP-1050N	-	isoform-comment:Shows reduced ability to bind to Ras and 14-3-3 proteins.	-	figure legend:Fig. 3|negative:The interaction does not occur under these experimental  conditions|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:6g4wEXS1EKGBUMTrLAbbjPWsmZw9606	rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw9606	intact-crc:67FF8FD5F6119038|rigid:/HM+Zc+LRMQdimRU62Fo0K5YIhw	true	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54253	uniprotkb:P51448	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	intact:EBI-1169722|uniprotkb:P70283|uniprotkb:P97741|uniprotkb:P97773|uniprotkb:Q923G1|ensembl:ENSMUSP00000034766	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:rora_mouse(display_long)|uniprotkb:Retinoid-related orphan receptor-alpha(gene name synonym)|uniprotkb:Nuclear receptor RZR-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 1(gene name synonym)|uniprotkb:Rora(gene name)|psi-mi:Rora(display_short)|uniprotkb:Nr1f1(gene name synonym)|uniprotkb:Rzra(gene name synonym)|uniprotkb:RAR-related orphan receptor A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Serra et al. (2006)	imex:IM-11999|pubmed:17110330	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1169812|imex:IM-11999-6	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU	refseq:NP_038674.1|refseq:NP_001276845.1|ensembl:ENSMUSG00000032238(gene)|ensembl:ENSMUST00000034766(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046068"(cGMP metabolic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|mint:P51448|reactome:R-MMU-383280|reactome:R-MMU-4090294|dip:DIP-35351N	omim:164400(primary-reference)|intact:EBI-1169792(see-also)|intact:EBI-1169800(see-also)|intact:EBI-1169758(see-also)	-	-	figure legend:5 B|comment:Neither GST-Atx-30Q, GST-Atx-53Q nor GST-ATx-82Q were able to pull down ROR-alpha.|negative:The interaction does not occur under these experimental  conditions.|comment:This result indicates that ATXN1 and ROR-alpha do not interact directly.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/24	2014/10/16	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	rogid:1wN5T6JsFmE3jJ3Nps7EfwUp5ho10090	intact-crc:E8723237023BE370|rigid:iv5eg6ppyCzdUfFNkBIuVNfyaCs	true	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q92466	uniprotkb:Q01094	intact:EBI-1176171|uniprotkb:Q76E54|uniprotkb:Q76E55|uniprotkb:Q76E56|uniprotkb:Q76E57|uniprotkb:B2R875|ensembl:ENSP00000256996	intact:EBI-448924|uniprotkb:Q13143|uniprotkb:Q92768|ensembl:ENSP00000345571	psi-mi:ddb2_human(display_long)|uniprotkb:Damage-specific DNA-binding protein 2(gene name synonym)|uniprotkb:DDB p48 subunit(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 2(gene name synonym)|uniprotkb:DDB2(gene name)|psi-mi:DDB2(display_short)	psi-mi:e2f1_human(display_long)|uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)|uniprotkb:PBR3(gene name synonym)|uniprotkb:E2F1(gene name)|psi-mi:E2F1(display_short)|uniprotkb:RBBP3(gene name synonym)|uniprotkb:pRB-binding protein E2F-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hayes et al. (1998)	pubmed:9418871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1213861	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000098.1|refseq:NP_001287663.1|ensembl:ENSG00000134574(gene)|ensembl:ENST00000256996(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0009411"(response to UV)|go:"GO:0030054"(cell junction)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR033312|interpro:IPR036322|rcsb pdb:3EI4|rcsb pdb:3I7L|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6796648|reactome:R-HSA-8951664|dip:DIP-36670N	refseq:NP_005216.1|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|ensembl:ENSG00000101412(gene)|ensembl:ENST00000343380(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804116|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q01094|rcsb pdb:1H24|rcsb pdb:1O9K|rcsb pdb:2AZE|rcsb pdb:5M9N|rcsb pdb:5M9O|rcsb pdb:6G0P|rcsb pdb:6ULS|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|dip:DIP-24227N	intact:EBI-12137777(see-also)	-	-	negative:The interaction does not occur under these experimental conditions.|figure legend:5|comment:p48 DDB does not coprecipitate with E2F1 when the cells are not co-transfected with p125 DDB, although E2F1 does coprecipitate with p48 DDB in the reciprocal coimmunoprecipitation.|delivery method:Q01094; Q92466 transfected.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/03/14	2014/10/16	rogid:HkT35Q/boNG3Gc5ZH4PzTwrMebU9606	rogid:vPNenpmxyXpHjMzUID54cwMFk+Y9606	intact-crc:130DD8914849FD41|rigid:iH07a2dcJotpHrad0Hy0pyE/NGs	true	t7 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P0DPB3-1	uniprotkb:P35240-1	intact:EBI-1397518|uniprotkb:Q9P0W5-1	intact:EBI-1014500|ensembl:ENSP00000344666	psi-mi:p0dpb3-1(display_long)|uniprotkb:SCHIP1(gene name)|psi-mi:SCHIP1(display_short)|uniprotkb:SCHIP-1(isoform synonym)|uniprotkb:SCHIP-1a(isoform synonym)	psi-mi:p35240-1(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Goutebroze et al. (2000)	pubmed:10669747|imex:IM-19739	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1397610	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1397509(schi1_human)	intact:EBI-1014472(merl_human)|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)	-	-	-	negative:The interaction does not occur under these experimental conditions.|comment:Interaction occurs using a NF2 fragment 1-314.|figure legend:7A and B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/09/15	2014/10/16	rogid:5SaF6+Frx9BAVDmnE0jqxntT3eM9606	rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606	intact-crc:1601DBE8D2EF4818|rigid:UErTUld3ajcS5SmvdpZWbWplXbw	true	ha tag:?-?	vsv tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q14141	uniprotkb:O14512-2	intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524	intact:EBI-1539620	psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym)	psi-mi:o14512-2(display_long)|uniprotkb:SOCS7(gene name)|psi-mi:SOCS7(display_short)|uniprotkb:NAP4(gene name synonym)|uniprotkb:SOCS6(gene name synonym)|uniprotkb:Nck, Ash and phospholipase C gamma-binding protein(gene name synonym)|uniprotkb:Nck-associated protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kremer et al. (2007)	imex:IM-11938|pubmed:17803907	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1539719|imex:IM-11938-4	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N	intact:EBI-1539606(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4B|negative:The interaction does not occur under these experimental conditions.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/28	2014/10/16	rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606	rogid:vRZltW+FvoMwFo5A9ROuFZ6lc7Q9606	intact-crc:4630A6A397714505|rigid:MV94z77TCKm6neLwwSEzetMNv/g	true	-	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32468	uniprotkb:Q12280	intact:EBI-4182|uniprotkb:D3DL57|ensemblfungi:YHR107C	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:cdc12_yeast(display_long)|uniprotkb:CDC12(gene name)|psi-mi:CDC12(display_short)|uniprotkb:CLA10(gene name synonym)|uniprotkb:PSL7(gene name synonym)|uniprotkb:YHR107C(locus name)|uniprotkb:Septin(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Osman et al. (2002)	pubmed:12446742|imex:IM-18965	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1641890	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011975.1|sgd:S000001149|dip:DIP-853N|mint:P32468|ensemblfungi:YHR107C(gene)|ensemblfungi:YHR107C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:A72DC393A6DBF924	-	figure legend:Fig. 3A|negative:This interaction does not occur under these experimental conditions.|delivery method:Q12280 transfection|delivery method:P32468 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/11/30	2014/10/16	rogid:RX1ddBeZj4BZ89IPrf0ZQdAX7AA559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	intact-crc:FA6E97C732F286C0|rigid:JdcY+wjFt6C7WXjndz54CouhvcE	true	green fluorescent protein tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UNQ0	uniprotkb:P11309-1	intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Xie et al. (2007)	pubmed:18056989|imex:IM-26546	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1578416	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	intact:EBI-1569536(see-also)	-	isoform-comment:Initiates from CTG codon.	figure legend:1 A|delivery method:Q9UNQ0; P11309-2 transfection|comment:The data suggest that this interaction requires both the N-terminal proline-rich region and the kinase domain present in Pim-1L but not Pim-1S.|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/12/18	2018/10/22	rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	intact-crc:D1F4BA0C3A6FF75F|rigid:G33OA2T/dS7E8ZVznBV8brYzjBA	true	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UNQ0	uniprotkb:P11309-1	intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0096"(pull down)	Xie et al. (2007)	pubmed:18056989|imex:IM-26546	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1578446	intact-miscore:0.52	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	intact:EBI-1569562(see-also)	-	isoform-comment:Initiates from CTG codon.	figure legend:1 B|comment:The data suggest that this interaction requires both the N-terminal proline-rich region and the kinase domain present in Pim-1L but not Pim-1S.|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/12/18	2018/10/30	rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	intact-crc:8CA58486076E0558|rigid:G33OA2T/dS7E8ZVznBV8brYzjBA	true	ha tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P84022	uniprotkb:O88898-6	intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973	intact:EBI-2338244	psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym)	psi-mi:o88898-6(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:DeltaN-gamma(isoform synonym)	psi-mi:"MI:0096"(pull down)	Adorno et al. (2009)	imex:IM-12172|pubmed:19345189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2338305|imex:IM-12172-10	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828	intact:EBI-2338025(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative splicing of isoform 2.	figure legend:Fig. 5A, Supp Fi. 7|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/18	2014/10/16	rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606	rogid:iEsa1BzRXYVPmccY2bYd0OeMqLQ10090	intact-crc:236F8042EC1EA960|rigid:mHwzQ4TJkSejXVJWBoEBpF0EsJI	true	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O01498-2	uniprotkb:Q09624	intact:EBI-3835446|ensemblmetazoa:C34G6.7b.1	intact:EBI-2529627|uniprotkb:Q09625|uniprotkb:Q969D4|ensemblmetazoa:ZK945.9.1	psi-mi:o01498-2(display_long)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym)|uniprotkb:C34G6.7(orf name)	psi-mi:pkd1_caeel(display_long)|uniprotkb:lov-1(gene name)|psi-mi:lov-1(display_short)|uniprotkb:pkd-1(gene name synonym)|uniprotkb:Polycystin-1(gene name synonym)|uniprotkb:Polycystic kidney disease 1 protein homolog(gene name synonym)|uniprotkb:ZK945.9/ZK945.10(orf name)	psi-mi:"MI:0018"(two hybrid)	Hu et al. (2007)	pubmed:17581863|imex:IM-16946	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3843554|imex:IM-16946-3	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-331248(isoform-parent)|ensemblmetazoa:WBGene00004109(gene)|ensemblmetazoa:C34G6.7b.1(transcript)	ensemblmetazoa:WBGene00003058(gene)|ensemblmetazoa:ZK945.9.1(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005929"(cilium)|go:"GO:0007617"(mating behavior)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0060179"(male mating behavior)|go:"GO:0097730"(non-motile cilium)|wormbase:ZK945.9|interpro:IPR000203(GPS)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|refseq:NP_496184.3|interpro:IPR036392|interpro:IPR042060	intact:EBI-3835065(see-also)	isoform-comment:No experimental confirmation available.	-	figure legend:Fig 1B.|caution:The number of amino acids in LOV-1has changed since this paper was published.  The numbering for the LOV-1 C-terminal 128 amino acids have been added  from the current UniProt version.|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/03/14	2014/10/16	rogid:BdMsWnueM4Ymwz2WOHrKlWhDg0Q6239	rogid:XcL3FOZDC1b/8cBoT7ZIFePtBaQ6239	intact-crc:2C69811E552A43BC|rigid:Om7EHGBDpf0/wNHYx6F8rvrAs+E	true	-	sufficient binding region:3157..3157-3284	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9-14	uniprotkb:Q9BZS1	intact:EBI-3989424|ensembl:ENSP00000462791	intact:EBI-983719|uniprotkb:O60827|uniprotkb:Q14DD8|intact:EBI-28970697|ensembl:ENSP00000365380|uniprotkb:Q4ZH51|uniprotkb:A5HJT1|uniprotkb:B7ZLG0|uniprotkb:B9UN80	psi-mi:q9ukt9-14(display_long)|uniprotkb:Aio-1-5a(isoform synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)	psi-mi:foxp3_human(display_long)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gandhi et al. (2010)	pubmed:20676092|imex:IM-16943	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3989406|imex:IM-16943-5	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747204(isoform-parent)|ensembl:ENSG00000161405(gene)|ensembl:ENST00000293068(transcript)	ensembl:ENST00000376199|ensembl:ENSP00000365372|ensembl:ENSP00000365380|ensembl:ENST00000518685|ensembl:ENSP00000428952|ensembl:ENST00000557224|ensembl:ENSP00000451208|ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QRF|rcsb pdb:4WK8|reactome:R-HSA-8877330|reactome:R-HSA-8939256|dip:DIP-36584N|refseq:NP_001107849.1|refseq:NP_054728.2	-	-	-	figure legend:Fig. 8B, 8D.|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/15	2014/10/16	rogid:N+6xy8C3/KaZEl+q1klrnogSLn89606	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	intact-crc:04F2D78EBB98D8E3|rigid:V2+p3PT/gQMre7OW1rf9ZHj3Ci4	true	flag tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P17844	uniprotkb:P04637-2	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	intact:EBI-3895853|ensembl:ENSP00000391127	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:p04637-2(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:I9RET(isoform synonym)|uniprotkb:p53beta(isoform synonym)	psi-mi:"MI:0096"(pull down)	Moore et al. (2010)	pubmed:20818423|imex:IM-15776	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1262"(I2D)	intact:EBI-3895924|imex:IM-15776-9	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	ensembl:ENSG00000141510(gene)|ensembl:ENST00000420246(transcript)|intact:EBI-366083(isoform-parent)|uniprotkb:P04637-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Expressed in quiescent lymphocytes. Seems to be non-functional. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:5a|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/28	2014/10/16	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rogid:FBRmcdqrBdNknSKl8D3E29TUjPQ9606	intact-crc:040EBF4A36558666|rigid:Fq9j7NnqbnWj6rnVJdc/JDkMQao	true	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P04637-3	uniprotkb:P17844	intact:EBI-3895857|ensembl:ENSP00000398846	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:p04637-3(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:p53gamma(isoform synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Moore et al. (2010)	pubmed:20818423|imex:IM-15776	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1262"(I2D)	intact:EBI-3895933|imex:IM-15776-8	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141510(gene)|ensembl:ENST00000455263(transcript)|intact:EBI-366083(isoform-parent)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	psi-mi:"MI:0469"(intact)	isoform-comment:Expressed in quiescent lymphocytes. Seems to be non-functional. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	figure legend:5a|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/28	2014/10/16	rogid:4SY2l/9BrflXtzgQtRKkGTQD3sk9606	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:9D1502C987504952|rigid:XmJ6Rw+REaoWBZMOuF69tMCsZvA	true	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P04637-8	uniprotkb:P17844	intact:EBI-3952497|ensembl:ENSP00000478499	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:p04637-8(display_long)|uniprotkb:Del133-p53beta(isoform synonym)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Moore et al. (2010)	pubmed:20818423|imex:IM-15776	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1262"(I2D)	intact:EBI-3954828|imex:IM-15776-6	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-366083(isoform-parent)|ensembl:ENSG00000141510(gene)|ensembl:ENST00000510385(transcript)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	psi-mi:"MI:0469"(intact)	isoform-comment:Produced by alternative promoter usage and alternative splicing.	-	figure legend:5a|negative:This experiment relates to a negative interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/28	2014/10/16	rogid:6+sFLQ5//4A0HOFWSILZEwCTq+M9606	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:40E9F7C2ECC91975|rigid:ZBtJnAFwl+9W1/yAnhVEIISgejQ	true	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P17844	uniprotkb:P04637-9	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	intact:EBI-3952501|ensembl:ENSP00000484409	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:p04637-9(display_long)|uniprotkb:Del133-p53gamma(isoform synonym)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)	psi-mi:"MI:0096"(pull down)	Moore et al. (2010)	pubmed:20818423|imex:IM-15776	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1262"(I2D)	intact:EBI-3954837|imex:IM-15776-7	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	intact:EBI-366083(isoform-parent)|ensembl:ENSG00000141510(gene)|ensembl:ENST00000504290(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative promoter usage and alternative splicing.	figure legend:5a|negative:This experiment relates to a negative interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/28	2014/10/16	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rogid:YdjrHkTnyrDmNdEKfBWEQ9S8HmA9606	intact-crc:CE4826B9AF9D26B5|rigid:AdNv6SWP/+NfxgGFBvgb22Zxl94	true	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q6Y5D8	uniprotkb:Q29502	intact:EBI-4396535|uniprotkb:Q6Y5D6|uniprotkb:Q6Y5D7|uniprotkb:Q99MT3|uniprotkb:Q99MT4|ensembl:ENSMUSP00000075658	intact:EBI-4396569|ensembl:ENSOCUP00000007111	psi-mi:rhg10_mouse(display_long)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)	psi-mi:pak2_rabit(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Koeppel et al. (2004)	pubmed:15471851|imex:IM-16837	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4406615|imex:IM-16837-10	intact-miscore:0.53	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_084389.2|refseq:XP_017168506.1|refseq:XP_006531558.1|refseq:XP_006531561.1|refseq:XP_006531563.1|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149	refseq:NP_001076225.1|refseq:XP_017202139.1|ensembl:ENSOCUG00000008224(gene)|ensembl:ENSOCUT00000008227(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)	-	-	-	figure legend:1a|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/09/02	2014/10/16	rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090	rogid:MXhqo/KRMzv+6/6Nh1lMly490J49986	intact-crc:10F9981E90F3D8C9|rigid:qVX8hV7CQ0KM6QnrPZa1ztRlM6c	true	sufficient binding region:665-786	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6Y5D8	uniprotkb:Q29502	intact:EBI-4396535|uniprotkb:Q6Y5D6|uniprotkb:Q6Y5D7|uniprotkb:Q99MT3|uniprotkb:Q99MT4|ensembl:ENSMUSP00000075658	intact:EBI-4396569|ensembl:ENSOCUP00000007111	psi-mi:rhg10_mouse(display_long)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)	psi-mi:pak2_rabit(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koeppel et al. (2004)	pubmed:15471851|imex:IM-16837	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4406589|imex:IM-16837-9	intact-miscore:0.53	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_084389.2|refseq:XP_017168506.1|refseq:XP_006531558.1|refseq:XP_006531561.1|refseq:XP_006531563.1|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149	refseq:NP_001076225.1|refseq:XP_017202139.1|ensembl:ENSOCUG00000008224(gene)|ensembl:ENSOCUT00000008227(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)	-	-	-	figure legend:1b|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/02	2014/10/16	rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090	rogid:MXhqo/KRMzv+6/6Nh1lMly490J49986	intact-crc:E4BD8FC012A6D98B|rigid:qVX8hV7CQ0KM6QnrPZa1ztRlM6c	true	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q29502	uniprotkb:Q6Y5D8-1	intact:EBI-4396569|ensembl:ENSOCUP00000007111	intact:EBI-4396677|ensembl:ENSMUSP00000075658	psi-mi:pak2_rabit(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym)	psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koeppel et al. (2004)	pubmed:15471851|imex:IM-16837	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4396700|imex:IM-16837-5	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001076225.1|refseq:XP_017202139.1|ensembl:ENSOCUG00000008224(gene)|ensembl:ENSOCUT00000008227(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)	intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)	-	-	-	figure legend:5b|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/02	2014/10/16	rogid:MXhqo/KRMzv+6/6Nh1lMly490J49986	rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090	intact-crc:2771632B6A011128|rigid:qVX8hV7CQ0KM6QnrPZa1ztRlM6c	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q29502	uniprotkb:Q6Y5D8-1	intact:EBI-4396569|ensembl:ENSOCUP00000007111	intact:EBI-4396677|ensembl:ENSMUSP00000075658	psi-mi:pak2_rabit(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym)	psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koeppel et al. (2004)	pubmed:15471851|imex:IM-16837	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4396713|imex:IM-16837-6	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001076225.1|refseq:XP_017202139.1|ensembl:ENSOCUG00000008224(gene)|ensembl:ENSOCUT00000008227(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)	intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)	-	-	-	figure legend:5c|negative:The interaction didin't happen when the full-length form of pak2 was used.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/02	2014/10/16	rogid:MXhqo/KRMzv+6/6Nh1lMly490J49986	rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090	intact-crc:E1D8E31088419CD7|rigid:qVX8hV7CQ0KM6QnrPZa1ztRlM6c	true	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6Y5D8-1	uniprotkb:Q29502	intact:EBI-4396677|ensembl:ENSMUSP00000075658	intact:EBI-4396569|ensembl:ENSOCUP00000007111	psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)	psi-mi:pak2_rabit(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koeppel et al. (2004)	pubmed:15471851|imex:IM-16837	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4396664|imex:IM-16837-4	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)	refseq:NP_001076225.1|refseq:XP_017202139.1|ensembl:ENSOCUG00000008224(gene)|ensembl:ENSOCUT00000008227(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)	-	-	-	figure legend:5a|negative:Interaction didn't happen with the full-lenght version of pak2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/02	2014/10/16	rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090	rogid:MXhqo/KRMzv+6/6Nh1lMly490J49986	intact-crc:CB8ACD9559468A38|rigid:qVX8hV7CQ0KM6QnrPZa1ztRlM6c	true	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49755	uniprotkb:P17706-2	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	intact:EBI-4480135|ensembl:ENSP00000320298	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:p17706-2(display_long)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:p45TC(isoform synonym)|uniprotkb:TC45(isoform synonym)|uniprotkb:PTPA(isoform synonym)|uniprotkb:TC-PTPa(isoform synonym)	psi-mi:"MI:0018"(two hybrid)	Gupta et al. (2006)	pubmed:16595549	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4480162	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	ensembl:ENSG00000175354(gene)|ensembl:ENST00000327283(transcript)|intact:EBI-984930(isoform-parent)	intact:EBI-4409514(see-also)	-	isoform-comment:"Major isoform. Contains a phosphoserine at position 304. Contains a nuclear location signal at positions 377-381 (Ref.8) and an autoinhibitory region acting through intramolecular interactions is found at positions 353-387."	figure legend:1B|negative:The interaction does not occur under these experimental  conditions.|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/09/22	2014/10/16	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HS97gCRD0kvbApH6CkrrBjfSM1o9606	intact-crc:91F4B1D22D3C8367|rigid:rFHS4hf2ubM1Z7TeTug/rNCpt2Y	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17706-2	uniprotkb:Q9BVK6	intact:EBI-4480135|ensembl:ENSP00000320298	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:p17706-2(display_long)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:p45TC(isoform synonym)|uniprotkb:TC45(isoform synonym)|uniprotkb:PTPA(isoform synonym)|uniprotkb:TC-PTPa(isoform synonym)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gupta et al. (2006)	pubmed:16595549	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4480160	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175354(gene)|ensembl:ENST00000327283(transcript)|intact:EBI-984930(isoform-parent)	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	intact:EBI-4409518(see-also)	isoform-comment:"Major isoform. Contains a phosphoserine at position 304. Contains a nuclear location signal at positions 377-381 (Ref.8) and an autoinhibitory region acting through intramolecular interactions is found at positions 353-387."	-	figure legend:1B|negative:The interaction does not occur under these experimental  conditions|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/09/22	2014/10/16	rogid:HS97gCRD0kvbApH6CkrrBjfSM1o9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	intact-crc:B2677602F8D71659|rigid:UEo12rEF1ZaY6FQbwCHtvPa92nY	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13546	uniprotkb:O43464	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808	intact:EBI-517086|uniprotkb:Q9HBZ4|uniprotkb:Q9P0Y3|uniprotkb:Q9P0Y4|ensembl:ENSP00000258080	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:htra2_human(display_long)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)|uniprotkb:HTRA2(gene name)|psi-mi:HTRA2(display_short)|uniprotkb:PRSS25(gene name synonym)|uniprotkb:OMI(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Vande et al. (2010)	pubmed:20125124|imex:IM-16866	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4423191|imex:IM-16866-3	intact-miscore:0.44	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process)	refseq:NP_037379.1|refseq:NP_659540.1|refseq:NP_001308656.1|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:O43464|rcsb pdb:1LCY|rcsb pdb:2PZD|rcsb pdb:5FHT|rcsb pdb:5M3N|rcsb pdb:5M3O|rcsb pdb:5TNY|ensembl:ENSG00000115317(gene)|ensembl:ENST00000258080(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048666"(neuron development)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071300"(cellular response to retinoic acid)|rcsb pdb:5TNZ|rcsb pdb:5TO0|rcsb pdb:5TO1|rcsb pdb:5WYN	go:"GO:0008233"(peptidase activity)|go:"GO:0006508"(proteolysis)	-	-	figure legend:4f|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/05	2014/10/16	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	rogid:IaLYfoH7H9K64U0KrEY7iB1vAfU9606	intact-crc:E166FC4949DDB82C|rigid:8LKKyo9S0452UkfGDyKEl1aB5cs	true	35s radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q14790	uniprotkb:Q13158	intact:EBI-78060|ensembl:ENSP00000412523|ensembl:ENSP00000501268|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Rebe et al. (2007)	pubmed:17047155|imex:IM-17275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4567600|imex:IM-17275-2	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|ensembl:ENSG00000064012(gene)|ensembl:ENST00000432109(transcript)|ensembl:ENST00000673742(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0009409"(response to cold)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0070269"(pyroptosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|reactome:R-HSA-264870|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QDU|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_005246943.1|dip:DIP-30915N	refseq:NP_003815.1|dip:DIP-286N|ensembl:ENSG00000168040(gene)|ensembl:ENST00000301838(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928	intact:EBI-4567587(see-also)	-	-	figure legend:2a|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2011/10/19	2014/10/16	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:49D37AFAAEFE2806|rigid:Pp/aS839xH6nHH2VM1FMPfgwak8	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14790	uniprotkb:Q13546	intact:EBI-78060|ensembl:ENSP00000412523|ensembl:ENSP00000501268|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Rebe et al. (2007)	pubmed:17047155|imex:IM-17275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4567600|imex:IM-17275-2	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|ensembl:ENSG00000064012(gene)|ensembl:ENST00000432109(transcript)|ensembl:ENST00000673742(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0009409"(response to cold)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0070269"(pyroptosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|reactome:R-HSA-264870|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QDU|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_005246943.1|dip:DIP-30915N	refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process)	intact:EBI-4567587(see-also)	-	-	figure legend:2a|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2011/10/19	2014/10/16	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:49D37AFAAEFE2806|rigid:Pp/aS839xH6nHH2VM1FMPfgwak8	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14790	uniprotkb:O15519-1	intact:EBI-78060|ensembl:ENSP00000412523|ensembl:ENSP00000501268|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81	intact:EBI-4567563|intact:EBI-7093779|intact:MINT-2589696|intact:EBI-7093972|intact:EBI-7093921|intact:EBI-7093724|intact:EBI-7093827|intact:EBI-8019287|intact:EBI-7158298|intact:EBI-7093876|ensembl:ENSP00000312455|ensembl:ENSP00000399420	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:o15519-1(display_long)|uniprotkb:FLIP-L(isoform synonym)|uniprotkb:CLARP1(isoform synonym)|uniprotkb:MRIT alpha-1(isoform synonym)|uniprotkb:CASH alpha(isoform synonym)|uniprotkb:I-FLICE 1(isoform synonym)|uniprotkb:FLAME-1 gamma(isoform synonym)|uniprotkb:Usurpin alpha(isoform synonym)|uniprotkb:CFLAR(gene name)|psi-mi:CFLAR(display_short)|uniprotkb:CASH(gene name synonym)|uniprotkb:CASP8AP1(gene name synonym)|uniprotkb:CLARP(gene name synonym)|uniprotkb:MRIT(gene name synonym)|uniprotkb:Caspase homolog(gene name synonym)|uniprotkb:Caspase-eight-related protein(gene name synonym)|uniprotkb:Caspase-like apoptosis regulatory protein(gene name synonym)|uniprotkb:Cellular FLICE-like inhibitory protein(gene name synonym)|uniprotkb:FADD-like antiapoptotic molecule 1(gene name synonym)|uniprotkb:Inhibitor of FLICE(gene name synonym)|uniprotkb:MACH-related inducer of toxicity(gene name synonym)|uniprotkb:Usurpin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Rebe et al. (2007)	pubmed:17047155|imex:IM-17275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4567600|imex:IM-17275-2	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|ensembl:ENSG00000064012(gene)|ensembl:ENST00000432109(transcript)|ensembl:ENST00000673742(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0009409"(response to cold)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0070269"(pyroptosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|reactome:R-HSA-264870|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QDU|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_005246943.1|dip:DIP-30915N	intact:EBI-514941(isoform-parent)|ensembl:ENSG00000003402(gene)|ensembl:ENST00000309955(transcript)|ensembl:ENST00000423241(transcript)	intact:EBI-4567587(see-also)	-	-	figure legend:2a|negative:The interaction does not occur under these experimental conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2011/10/19	2014/10/16	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rogid:kpksW8E51awRfZkhWEGFlrdgnJ89606	intact-crc:49D37AFAAEFE2806|rigid:Pp/aS839xH6nHH2VM1FMPfgwak8	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42866-1	uniprotkb:P21729	intact:EBI-6049693|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	intact:EBI-6049651|uniprotkb:Q53WV4|ensembl:ENSMUSP00000033730	psi-mi:p42866-1(display_long)|uniprotkb:MOR-1(isoform synonym)|uniprotkb:MOR-H(isoform synonym)|uniprotkb:MOR-1J(isoform synonym)|uniprotkb:MOR-1T(isoform synonym)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:grpr_mouse(display_long)|uniprotkb:Grpr(gene name)|psi-mi:Grpr(display_short)|uniprotkb:GRP-preferring bombesin receptor(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2011)	pubmed:22000021|imex:IM-17128	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049680|imex:IM-17128-2	intact-miscore:0.56	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282656(isoform-parent)|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)	refseq:NP_032203.1|ensembl:ENSMUSG00000031364(gene)|ensembl:ENSMUST00000033730(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004946"(bombesin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007611"(learning or memory)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0035176"(social behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043207"(response to external biotic stimulus)|go:"GO:0061744"(motor behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001556(Bombesin receptor)|interpro:IPR001966(Gastrin-releasing peptide receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476	-	-	-	figure legend:Fig. 3I|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord)	-	2011/10/31	2014/10/16	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rogid:OD1Wz8vbKJN/khDyJgbpC6Kxl2k10090	intact-crc:9E962E55FE992CCB|rigid:r5VmjRjPNwop537wuT3PZlz/R+Y	true	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P42866-1	uniprotkb:P21729	intact:EBI-6049693|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	intact:EBI-6049651|uniprotkb:Q53WV4|ensembl:ENSMUSP00000033730	psi-mi:p42866-1(display_long)|uniprotkb:MOR-1(isoform synonym)|uniprotkb:MOR-H(isoform synonym)|uniprotkb:MOR-1J(isoform synonym)|uniprotkb:MOR-1T(isoform synonym)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:grpr_mouse(display_long)|uniprotkb:Grpr(gene name)|psi-mi:Grpr(display_short)|uniprotkb:GRP-preferring bombesin receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:22000021|imex:IM-17128	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049760|imex:IM-17128-5	intact-miscore:0.56	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282656(isoform-parent)|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)	refseq:NP_032203.1|ensembl:ENSMUSG00000031364(gene)|ensembl:ENSMUST00000033730(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004946"(bombesin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007611"(learning or memory)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0035176"(social behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043207"(response to external biotic stimulus)|go:"GO:0061744"(motor behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001556(Bombesin receptor)|interpro:IPR001966(Gastrin-releasing peptide receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476	-	-	-	figure legend:Fig. 5B|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/10/31	2014/10/16	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rogid:OD1Wz8vbKJN/khDyJgbpC6Kxl2k10090	intact-crc:7A1B206FAD9F0F3D|rigid:r5VmjRjPNwop537wuT3PZlz/R+Y	true	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P21729	uniprotkb:P42866-1	intact:EBI-6049651|uniprotkb:Q53WV4|ensembl:ENSMUSP00000033730	intact:EBI-6049693|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:grpr_mouse(display_long)|uniprotkb:Grpr(gene name)|psi-mi:Grpr(display_short)|uniprotkb:GRP-preferring bombesin receptor(gene name synonym)	psi-mi:p42866-1(display_long)|uniprotkb:MOR-1(isoform synonym)|uniprotkb:MOR-H(isoform synonym)|uniprotkb:MOR-1J(isoform synonym)|uniprotkb:MOR-1T(isoform synonym)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:22000021|imex:IM-17128	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049769|imex:IM-17128-6	intact-miscore:0.56	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032203.1|ensembl:ENSMUSG00000031364(gene)|ensembl:ENSMUST00000033730(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004946"(bombesin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007611"(learning or memory)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0035176"(social behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043207"(response to external biotic stimulus)|go:"GO:0061744"(motor behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001556(Bombesin receptor)|interpro:IPR001966(Gastrin-releasing peptide receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476	intact:EBI-5282656(isoform-parent)|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)	-	-	-	figure legend:Fig. 5A|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/10/31	2014/10/16	rogid:OD1Wz8vbKJN/khDyJgbpC6Kxl2k10090	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	intact-crc:CEFF9A881AE18A9A|rigid:r5VmjRjPNwop537wuT3PZlz/R+Y	true	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P42866-1	uniprotkb:P21729	intact:EBI-6049693|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	intact:EBI-6049651|uniprotkb:Q53WV4|ensembl:ENSMUSP00000033730	psi-mi:p42866-1(display_long)|uniprotkb:MOR-1(isoform synonym)|uniprotkb:MOR-H(isoform synonym)|uniprotkb:MOR-1J(isoform synonym)|uniprotkb:MOR-1T(isoform synonym)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:grpr_mouse(display_long)|uniprotkb:Grpr(gene name)|psi-mi:Grpr(display_short)|uniprotkb:GRP-preferring bombesin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2011)	pubmed:22000021|imex:IM-17128	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049801|imex:IM-17128-8	intact-miscore:0.56	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282656(isoform-parent)|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)	refseq:NP_032203.1|ensembl:ENSMUSG00000031364(gene)|ensembl:ENSMUST00000033730(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004946"(bombesin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007611"(learning or memory)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0035176"(social behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043207"(response to external biotic stimulus)|go:"GO:0061744"(motor behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001556(Bombesin receptor)|interpro:IPR001966(Gastrin-releasing peptide receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476	-	-	-	figure legend:Fig. 5C|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord)	-	2011/10/31	2014/10/16	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rogid:OD1Wz8vbKJN/khDyJgbpC6Kxl2k10090	intact-crc:81E5EF113A774A2F|rigid:r5VmjRjPNwop537wuT3PZlz/R+Y	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96B01-3	uniprotkb:Q14565	intact:EBI-1178748	intact:EBI-930865|uniprotkb:Q08AI1|uniprotkb:Q99498|uniprotkb:Q9UH11|uniprotkb:A8K9A2|uniprotkb:B4DMW6|ensembl:ENSP00000216024	psi-mi:q96b01-3(display_long)|uniprotkb:RAD51AP1(gene name)|psi-mi:RAD51AP1(display_short)|uniprotkb:PIR51(gene name synonym)|uniprotkb:RAD51-interacting protein(gene name synonym)	psi-mi:dmc1_human(display_long)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:DMC1H(gene name synonym)|uniprotkb:LIM15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dunlop et al. (2011)	pubmed:21903585|imex:IM-17274|mint:MINT-8293155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5242225|imex:IM-17274-2	intact-miscore:0.44	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1178724(r51a1_human)	refseq:NP_008999.2|refseq:NP_001265137.1|refseq:XP_006724175.1|dip:DIP-24192N|ensembl:ENSG00000100206(gene)|ensembl:ENST00000216024(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0007292"(female gamete generation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0042148"(strand invasion)|go:"GO:0042802"(identical protein binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q14565|rcsb pdb:1V5W|rcsb pdb:2ZJB|rcsb pdb:4HYY|rcsb pdb:6R3P|rcsb pdb:7C98|rcsb pdb:7C99|rcsb pdb:7C9C|rcsb pdb:7CGY|reactome:R-HSA-912446	intact:EBI-5242173(see-also)	-	-	figure legend:6c|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/08	2014/10/16	rogid:AvIBgGd2iLbAPbQ9JiAA/4QGlfs9606	rogid:jEXzCV2BLjXzd5BCkQaFrrgIVdM9606	intact-crc:4A96E411E1108874|rigid:VztPPQhF92DEzZW9n3Wz7Al2bho	true	maltose binding protein tag:n-n|his tag:c-c	his tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q96HS1-1	uniprotkb:O00429	intact:EBI-5394422|ensembl:ENSP00000438465	intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5	psi-mi:q96hs1-1(display_long)|uniprotkb:PGAM5-L(isoform synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2012)	pubmed:22265414|imex:IM-16613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5394458|imex:IM-16613-2	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000247077(gene)|ensembl:ENST00000498926(transcript)|intact:EBI-713608(isoform-parent)	refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N	psi-mi:"MI:0469"(intact)	-	crc64:F9521A376B785B71	figure legend:Fig. 5F|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/01/30	2014/10/16	rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606	rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606	intact-crc:150B27BCA9438B7E|rigid:QBCl9g9EBekGl1BMbltf2oMHaS0	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21333	uniprotkb:P05556	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Loo et al. (1998)	pubmed:9722563|imex:IM-17229	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5627598|imex:IM-17229-3	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	intact:EBI-5627041(see-also)	-	-	figure legend:Fig. 2.|isoform-comment:The human filamin consists of three isoforms. The protein included in this entry is filamin A.|negative:This interaction is not supported by co-immunoprecipitation when filamin is immunoprecipitated with anti-filamin mAb and integrin beta-1 is checked for co-immunoprecipitation with integrin mAb.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2012/02/23	2014/10/16	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:F5D1EA98FAE1AADB|rigid:U1mrY8emn4Q3XnZvgtQ/3/p0R5c	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61097	uniprotkb:Q86Y07-2	intact:EBI-1536336|uniprotkb:Q61648|uniprotkb:Q78DX8|ensembl:ENSMUSP00000018478	intact:EBI-1207636|ensembl:ENSP00000497378	psi-mi:ksr1_mouse(display_long)|uniprotkb:Ksr1(gene name)|psi-mi:Ksr1(display_short)|uniprotkb:Ksr(gene name synonym)|uniprotkb:Protein Hb(gene name synonym)	psi-mi:q86y07-2(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym)|uniprotkb:VRK2B(isoform synonym)	psi-mi:"MI:0096"(pull down)	Fernandez et al. (2012)	pubmed:22752157|imex:IM-17102	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6173513	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006532398.1|refseq:NP_038599.1|refseq:NP_001335136.1|ensembl:ENSMUSG00000018334(gene)|ensembl:ENSMUST00000018478(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR025561|rcsb pdb:1KBE|rcsb pdb:1KBF|rcsb pdb:2LPE|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221	intact:EBI-1207615(vrk2_human)|ensembl:ENSG00000028116(gene)|ensembl:ENST00000648897(transcript)	intact:EBI-6173491(see-also)	-	isoform-comment:No experimental confirmation available	figure legend:2b|comment:Interactions were observed with all the fragments of KSR1 however, the interaction witht he AA402-873 remain the strongest.|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/30	2014/10/16	rogid:leYMsU3ncD6y5hMphnr/ks1rE2w10090	rogid:MnuaGzdqFBFcEN1JBa9Rqpii//I9606	intact-crc:0F36F775461BD11B|rigid:xoBVXX8h2QbXrmBYpokJZMqiIGU	true	flag tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NFJ9	uniprotkb:P48356-2	intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469	intact:EBI-6161269|ensembl:ENSMUSP00000102534	psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym)	psi-mi:p48356-2(display_long)|uniprotkb:Lepr(gene name)|psi-mi:Lepr(display_short)|uniprotkb:Db(gene name synonym)|uniprotkb:Obr(gene name synonym)|uniprotkb:B219(gene name synonym)|uniprotkb:OB receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Seo et al. (2009)	imex:IM-17356|pubmed:19150989	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6161248	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922	intact:EBI-2257257(isoform-parent)|ensembl:ENSMUSG00000057722(gene)|ensembl:ENSMUST00000106921(transcript)	intact:EBI-6143605(see-also)	-	-	figure legend:Fig 5B|negative:The interaction does not occur under these experimental conditions.‟|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/06/11	2014/10/16	rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606	rogid:jCpsw5ZFn6MACQ1ZtZy/oAS45kU10090	intact-crc:40AAF7DC1F2362CD|rigid:m1gbmv2Gld2pn7xAzuIzzdO0r/4	true	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75367-2	uniprotkb:P04626	intact:EBI-6249599|ensembl:ENSP00000310169	intact:EBI-641062|ensembl:ENSP00000269571|uniprotkb:Q14256|uniprotkb:Q6LDV1|uniprotkb:Q9UMK4|uniprotkb:B2RZG3|uniprotkb:B4DHN3|uniprotkb:X5D2V5	psi-mi:o75367-2(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym)|uniprotkb:mH2A1.1(isoform synonym)	psi-mi:erbb2_human(display_long)|uniprotkb:p185erbB2(gene name synonym)|uniprotkb:MLN19(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:ERBB2(gene name)|psi-mi:ERBB2(display_short)|uniprotkb:HER2(gene name synonym)|uniprotkb:NEU(gene name synonym)|uniprotkb:NGL(gene name synonym)|uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2012)	pubmed:22589551|imex:IM-17421	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6249591	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2868511(isoform-parent)|ensembl:ENSG00000113648(gene)|ensembl:ENST00000312469(transcript)|uniprotkb:O75367-2(isoform-parent)	rcsb pdb:4HRN|rcsb pdb:5K33|rcsb pdb:5KWG|rcsb pdb:5MY6|rcsb pdb:5O4G|rcsb pdb:5OB4|rcsb pdb:5TQS|rcsb pdb:6ATT|rcsb pdb:6BGT|rcsb pdb:6J71|rcsb pdb:6LBX|rcsb pdb:6OGE|reactome:R-HSA-1227986|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-1306955|reactome:R-HSA-1358803|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-416572|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|ensembl:ENSG00000141736(gene)|ensembl:ENST00000269571(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|mint:P04626|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1MW4|rcsb pdb:1N8Z|rcsb pdb:1OVC|rcsb pdb:1QR1|rcsb pdb:1S78|rcsb pdb:2A91|rcsb pdb:2JWA|rcsb pdb:2KS1|rcsb pdb:2L4K|rcsb pdb:2N2A|rcsb pdb:3BE1|rcsb pdb:3H3B|rcsb pdb:3MZW|rcsb pdb:3N85|rcsb pdb:3PP0|rcsb pdb:3RCD|rcsb pdb:3WLW|rcsb pdb:3WSQ|rcsb pdb:4GFU|rcsb pdb:4HRL|rcsb pdb:4HRM|go:"GO:0010008"(endosome membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|refseq:NP_004439.2|dip:DIP-8N|refseq:NP_001005862.1|refseq:NP_001276865.1|refseq:NP_001276867.1	intact:EBI-6249554(see-also)	isoform-comment:Specifically binds ADP-ribose and O-acetyl-ADP-ribose. Important residues for binding are Asp-203, Gly-224, Gly-314 and Phe-348. Preferentially expressed over isoform 2 in the absence of DDX5/DDX17.	-	figure legend:Fig 3A|negative:The interaction does not occur under these experimental conditions.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/19	2014/10/16	rogid:zfozo/4qH34Xx6CBG+YnCuM2prk9606	rogid:6o8GoqTQ64og/aKbzFZZMQ8gRHI9606	intact-crc:DD7B6339CD5631FC|rigid:YiTR+zTATw3U8c1+ESTJd3FvlCQ	true	his tag:c-c|myc tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63104	uniprotkb:Q12824	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Angrand et al. (2006)	pubmed:16959763|imex:IM-17709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6272350|imex:IM-17709-7	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N	go:"GO:0005634"(nucleus)|intact:EBI-6272323(see-also)	-	-	figure legend:Fig 2E|negative:The interaction does not occur under these experimental  conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/20	2014/10/16	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:592B15D34FB93603|rigid:h0yafPrrVzc4KAcuLqN5VV4yDfE	true	ha tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P42566	uniprotkb:P98078-3	intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798	intact:EBI-6305891	psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym)	psi-mi:p98078-3(display_long)|uniprotkb:Dab2(gene name)|psi-mi:Dab2(display_short)|uniprotkb:Doc2(gene name synonym)|uniprotkb:Mitogen-responsive phosphoprotein(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Teckchandani et al. (2012)	imex:IM-17871|pubmed:22648170	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6354102	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N	intact:EBI-1391846(isoform-parent)	intact:EBI-6307006(see-also)	-	-	figure legend:1B|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/09/26	2014/10/16	rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606	rogid:sej1jmwA/j9VzJ56ris0qAl3LG010090	intact-crc:AC5267EDB36C08AF|rigid:OYIR/g+Cvjp/820K894vMPx0Y5I	true	-	t7 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86Y07-2	uniprotkb:Q07817-1	intact:EBI-1207636|ensembl:ENSP00000497378	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	psi-mi:q86y07-2(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym)|uniprotkb:VRK2B(isoform synonym)	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:"MI:0096"(pull down)	Monsalve et al. (2013)	pubmed:23449449|imex:IM-18530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6554686	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1207615(vrk2_human)|ensembl:ENSG00000028116(gene)|ensembl:ENST00000648897(transcript)	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	-	isoform-comment:No experimental confirmation available	-	figure legend:1d|negative:The interaction does not occur under these experimental  conditions.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/01/10	2014/10/16	rogid:MnuaGzdqFBFcEN1JBa9Rqpii//I9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	intact-crc:5BC9EEC08970432F|rigid:v+w6Rryau2HPgyNZE9SPjjulMWY	true	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q90998	uniprotkb:P01137	intact:EBI-6620843|ensembl:ENSGALP00000032713	intact:EBI-779636|uniprotkb:Q9UCG4|uniprotkb:A8K792	psi-mi:q90998_chick(display_long)|uniprotkb:TGFBR3(gene name)|psi-mi:TGFBR3(display_short)	psi-mi:tgfb1_human(display_long)|uniprotkb:TGFB1(gene name)|psi-mi:TGFB1(display_short)|uniprotkb:TGFB(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Brown et al. (1999)	pubmed:10092230|imex:IM-26106	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6622428	replication-based confidence:3|intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989670.1|ensembl:ENSGALG00000006038(gene)|ensembl:ENSGALT00000033354(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001654"(eye development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007181"(transforming growth factor beta receptor complex assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016049"(cell growth)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0034699"(response to luteinizing hormone)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0016477"(cell migration)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0048185"(activin binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0030324"(lung development)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070123"(transforming growth factor beta receptor activity, type III)|interpro:IPR001507(Endoglin/CD105 antigen)|go:"GO:0031012"(extracellular matrix)|interpro:IPR017977|interpro:IPR042235|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0034673"(inhibin-betaglycan-ActRII complex)	refseq:NP_000651.3|mint:P01137|dip:DIP-5934N|go:"GO:0000165"(MAPK cascade)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003823"(antigen binding)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0014008"(positive regulation of microglia differentiation)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021915"(neural tube development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0034714"(type III transforming growth factor beta receptor binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043932"(ossification involved in bone remodeling)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045918"(negative regulation of cytolysis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048535"(lymph node development)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051098"(regulation of binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072562"(blood microparticle)|go:"GO:0085029"(extracellular matrix assembly)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|go:"GO:1905313"(transforming growth factor beta receptor signaling pathway involved in heart development)|go:"GO:1990402"(embryonic liver development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR003939(Transforming growth factor, beta 1)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR016319(Transforming growth factor-beta)|interpro:IPR017948|interpro:IPR029034|rcsb pdb:1KLA|rcsb pdb:1KLC|rcsb pdb:1KLD|rcsb pdb:3KFD|rcsb pdb:4KV5|rcsb pdb:5FFO|rcsb pdb:5VQP|rcsb pdb:6OM2|rcsb pdb:6P7J|reactome:R-HSA-114608|reactome:R-HSA-168277|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-3304356|reactome:R-HSA-3642279|reactome:R-HSA-3645790|reactome:R-HSA-3656532|reactome:R-HSA-3656535|reactome:R-HSA-381340|reactome:R-HSA-5689603|reactome:R-HSA-6785807|reactome:R-HSA-8941855|reactome:R-HSA-8941858|reactome:R-HSA-8951936	-	-	-	figure legend:1C|negative:The interaction does not occur under these conditions|comment:Binding of TBRIII and TGFB1 reduces as concentration of antiserum against extracellular domain of TBRIII increases|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_fibroblast)|taxid:9031(Chick embryonic fibroblasts)	-	2013/04/23	2014/10/16	rogid:VB1sTkd4YhvznGA4BspXxQEyXOg9031	rogid:WjHm8ysG9Ab1pFfdtG9QbJeCdCw9606	intact-crc:E0E6AFB4BFB24F5F|rigid:w+7KFn+nspfTBANqeJ+TfmVItE4	true	-	125i radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P03255-2	uniprotkb:P29590	intact:EBI-6859460|intact:EBI-7796221|intact:EBI-8665485|intact:EBI-7796198|intact:EBI-6996423|intact:EBI-7427771|intact:EBI-8679750|intact:EBI-8544261|intact:EBI-8646018|intact:EBI-8646062|intact:EBI-8646168|intact:EBI-7427730|intact:EBI-8053186|intact:EBI-8645976|intact:EBI-8646143|intact:EBI-8665537|intact:EBI-7427512|intact:EBI-8544381|intact:MINT-87562|intact:EBI-8544435|intact:EBI-8679721|intact:EBI-8665366|intact:EBI-7140610|intact:EBI-8646114|intact:EBI-8665567|intact:EBI-7140682|intact:EBI-8544418	intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7	psi-mi:p03255-2(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:243R(isoform synonym)|uniprotkb:S-E1A(isoform synonym)	psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861008	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2603114(isoform-parent)	ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N	go:"GO:0016605"(PML body)|intact:EBI-6692443(see-also)	isoform-comment:No experimental confirmation available.	-	figure legend:1 and 2|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma)	-	2013/05/28	2014/10/16	rogid:3OSlEpVJ8y6MDaS6uIIUi38tgKM28285	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	intact-crc:CF3FEA9606A0F772|rigid:KTsoKUv5Ti1XW0qiLhmdGCvA8HY	true	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P29590	uniprotkb:P03255-2	intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7	intact:EBI-6859460|intact:EBI-7796221|intact:EBI-8665485|intact:EBI-7796198|intact:EBI-6996423|intact:EBI-7427771|intact:EBI-8679750|intact:EBI-8544261|intact:EBI-8646018|intact:EBI-8646062|intact:EBI-8646168|intact:EBI-7427730|intact:EBI-8053186|intact:EBI-8645976|intact:EBI-8646143|intact:EBI-8665537|intact:EBI-7427512|intact:EBI-8544381|intact:MINT-87562|intact:EBI-8544435|intact:EBI-8679721|intact:EBI-8665366|intact:EBI-7140610|intact:EBI-8646114|intact:EBI-8665567|intact:EBI-7140682|intact:EBI-8544418	psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:p03255-2(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:243R(isoform synonym)|uniprotkb:S-E1A(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861269	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N	intact:EBI-2603114(isoform-parent)	intact:EBI-6692484(see-also)	-	isoform-comment:No experimental confirmation available.	figure legend:5C|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	rogid:3OSlEpVJ8y6MDaS6uIIUi38tgKM28285	intact-crc:A226E413A95A8017|rigid:KTsoKUv5Ti1XW0qiLhmdGCvA8HY	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03255-1	uniprotkb:P29590-5	intact:EBI-6692439|intact:EBI-8544317|intact:EBI-8665409|intact:EBI-8665441|intact:EBI-8544462|intact:EBI-8544536|intact:EBI-8665603|intact:EBI-8544558|intact:MINT-87557|intact:EBI-8544293|intact:EBI-8544365|intact:EBI-8665466	intact:EBI-304008|ensembl:ENSP00000378567	psi-mi:p03255-1(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:289R(isoform synonym)|uniprotkb:L-E1A(isoform synonym)	psi-mi:p29590-5(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-IV(isoform synonym)|uniprotkb:PML-X(isoform synonym)|uniprotkb:TRIM19zeta(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861335	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2603114(isoform-parent)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000395135(transcript)	intact:EBI-6692468(see-also)	-	-	figure legend:3D|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285	rogid:sGzdYcuKdN6Kj34uS498dlF77PY9606	intact-crc:D7BF1AAC68CE6AD2|rigid:YwEMHrjD5WqrSIYiMyaL5zCSMNM	true	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29590-9	uniprotkb:P03255-1	intact:EBI-6861318|ensembl:ENSP00000455612	intact:EBI-6692439|intact:EBI-8544317|intact:EBI-8665409|intact:EBI-8665441|intact:EBI-8544462|intact:EBI-8544536|intact:EBI-8665603|intact:EBI-8544558|intact:MINT-87557|intact:EBI-8544293|intact:EBI-8544365|intact:EBI-8665466	psi-mi:p29590-9(display_long)|uniprotkb:PML-III(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:p03255-1(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:289R(isoform synonym)|uniprotkb:L-E1A(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861314	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000569477(transcript)|intact:EBI-295890(isoform-parent)	intact:EBI-2603114(isoform-parent)	intact:EBI-6692468(see-also)	-	-	figure legend:3D|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:9aXmsurp88slsomTzxBdfrfEomw9606	rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285	intact-crc:6D77D09A2F376FA6|rigid:2sKNF4WP68wuucfF2gSJIfY0YAU	true	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29590-4	uniprotkb:P03255-1	intact:EBI-304004|ensembl:ENSP00000394642|ensembl:ENSP00000456486	intact:EBI-6692439|intact:EBI-8544317|intact:EBI-8665409|intact:EBI-8665441|intact:EBI-8544462|intact:EBI-8544536|intact:EBI-8665603|intact:EBI-8544558|intact:MINT-87557|intact:EBI-8544293|intact:EBI-8544365|intact:EBI-8665466	psi-mi:p29590-4(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-3B(isoform synonym)|uniprotkb:PML-VI(isoform synonym)|uniprotkb:TRIM19epsilon(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:p03255-1(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:289R(isoform synonym)|uniprotkb:L-E1A(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861349	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000436891(transcript)|ensembl:ENST00000569965(transcript)	intact:EBI-2603114(isoform-parent)	intact:EBI-6692468(see-also)	isoform-comment:Contains a phosphoserine at position 518. Contains a phosphoserine at position 527. Contains a phosphoserine at position 530.	-	figure legend:3D|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:7Qv+/MeEQm0nHBnZdudPQApmaQk9606	rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285	intact-crc:CDD10B28E79BAA19|rigid:dLetkuU+wI+XTlfZwTkDYKXAnQo	true	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03255-2	uniprotkb:P29590-8	intact:EBI-6859460|intact:EBI-7796221|intact:EBI-8665485|intact:EBI-7796198|intact:EBI-6996423|intact:EBI-7427771|intact:EBI-8679750|intact:EBI-8544261|intact:EBI-8646018|intact:EBI-8646062|intact:EBI-8646168|intact:EBI-7427730|intact:EBI-8053186|intact:EBI-8645976|intact:EBI-8646143|intact:EBI-8665537|intact:EBI-7427512|intact:EBI-8544381|intact:MINT-87562|intact:EBI-8544435|intact:EBI-8679721|intact:EBI-8665366|intact:EBI-7140610|intact:EBI-8646114|intact:EBI-8665567|intact:EBI-7140682|intact:EBI-8544418	intact:EBI-6692454|ensembl:ENSP00000268059	psi-mi:p03255-2(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:243R(isoform synonym)|uniprotkb:S-E1A(isoform synonym)	psi-mi:p29590-8(display_long)|uniprotkb:PML-II(isoform synonym)|uniprotkb:TRIM19kappa(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861483	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2603114(isoform-parent)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000268059(transcript)|intact:EBI-295890(isoform-parent)	intact:EBI-6692468(see-also)	isoform-comment:No experimental confirmation available.	-	figure legend:3B|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:3OSlEpVJ8y6MDaS6uIIUi38tgKM28285	rogid:9wX6YVhiy58Q92O5eYXFEJQRwQ89606	intact-crc:038E283A322B8B59|rigid:YHqBpKqWDc28P2FiBrZo/04965I	true	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29590-1	uniprotkb:P03255-1	intact:EBI-303992|ensembl:ENSP00000268058	intact:EBI-6692439|intact:EBI-8544317|intact:EBI-8665409|intact:EBI-8665441|intact:EBI-8544462|intact:EBI-8544536|intact:EBI-8665603|intact:EBI-8544558|intact:MINT-87557|intact:EBI-8544293|intact:EBI-8544365|intact:EBI-8665466	psi-mi:p29590-1(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-I(isoform synonym)|uniprotkb:TRIM19alpha(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:p03255-1(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:289R(isoform synonym)|uniprotkb:L-E1A(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861300	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000268058(transcript)	intact:EBI-2603114(isoform-parent)	intact:EBI-6692468(see-also)	-	-	figure legend:3D|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285	intact-crc:3C2BD3708501041F|rigid:S1an64TsOkfVvxeaWPOKp/Ty9Ss	true	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29590-2	uniprotkb:P03255-1	intact:EBI-303996|ensembl:ENSP00000395576	intact:EBI-6692439|intact:EBI-8544317|intact:EBI-8665409|intact:EBI-8665441|intact:EBI-8544462|intact:EBI-8544536|intact:EBI-8665603|intact:EBI-8544558|intact:MINT-87557|intact:EBI-8544293|intact:EBI-8544365|intact:EBI-8665466	psi-mi:p29590-2(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-2(isoform synonym)|uniprotkb:PML-V(isoform synonym)|uniprotkb:TRIM19beta(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:p03255-1(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:289R(isoform synonym)|uniprotkb:L-E1A(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Berscheminski et al. (2013)	imex:IM-20843|pubmed:23135708	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6861342	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000435786(transcript)|uniprotkb:P29590-2(isoform-parent)	intact:EBI-2603114(isoform-parent)	intact:EBI-6692468(see-also)	isoform-comment:"Ref.5 (AAG50181) sequence is in conflict in position: 578:P->A. Contains a phosphoserine at position 565."	-	figure legend:3D|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/05/28	2014/10/16	rogid:+fRuye0ANEW1KaFIUBFhHCMymZ09606	rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285	intact-crc:90B56E33C46728A3|rigid:8G/jo2lx68eUTs8n/gF5CsHAy9g	true	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12815	uniprotkb:Q8N114	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-2115556|uniprotkb:Q69YY9|uniprotkb:Q7Z433|uniprotkb:Q8NHL9|uniprotkb:Q96MW8|uniprotkb:Q9BV58|uniprotkb:B3KW99|uniprotkb:F8W9N8|intact:EBI-28987597|ensembl:ENSP00000296444	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:shsa5_human(display_long)|uniprotkb:SHISA5(gene name)|psi-mi:SHISA5(display_short)|uniprotkb:SCOTIN(gene name synonym)|uniprotkb:Scotin(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 120(gene name synonym)|uniprotkb:PSEC0133(orf name)	psi-mi:"MI:0096"(pull down)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6693634	intact-miscore:0.54	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:XP_011532098.1|refseq:NP_057563.3|refseq:XP_006713251.1|ensembl:ENSP00000296444|ensembl:ENST00000426002|ensembl:ENSP00000390388|ensembl:ENST00000442747|ensembl:ENSP00000408223|ensembl:ENST00000443308|ensembl:ENSP00000395373|ensembl:ENST00000444115|ensembl:ENSP00000407957|ensembl:ENST00000619810|ensembl:ENSP00000484992|refseq:NP_001258995.1|refseq:NP_001258996.1|refseq:NP_001258997.1|refseq:NP_001259011.1|refseq:NP_001259012.1|refseq:NP_001258994.1|refseq:XP_005265262.1|ensembl:ENSG00000164054(gene)|ensembl:ENST00000296444(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050699"(WW domain binding)|interpro:IPR026910|reactome:R-HSA-381426|reactome:R-HSA-8957275	intact:EBI-6693554(see-also)	-	-	figure legend:Fig. 2a|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:MLYJ9JCjKJoqnxTae9YhMWaWOM49606	intact-crc:1EA197E426371506|rigid:E9m6bi20KzPvRmuH91C4Z3FjJig	true	glutathione s tranferase tag:n-n	his tag:c-c|sufficient binding region:68-240	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P12815	uniprotkb:Q8N114	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-2115556|uniprotkb:Q69YY9|uniprotkb:Q7Z433|uniprotkb:Q8NHL9|uniprotkb:Q96MW8|uniprotkb:Q9BV58|uniprotkb:B3KW99|uniprotkb:F8W9N8|intact:EBI-28987597|ensembl:ENSP00000296444	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:shsa5_human(display_long)|uniprotkb:SHISA5(gene name)|psi-mi:SHISA5(display_short)|uniprotkb:SCOTIN(gene name synonym)|uniprotkb:Scotin(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 120(gene name synonym)|uniprotkb:PSEC0133(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6857432	intact-miscore:0.54	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:XP_011532098.1|refseq:NP_057563.3|refseq:XP_006713251.1|ensembl:ENSP00000296444|ensembl:ENST00000426002|ensembl:ENSP00000390388|ensembl:ENST00000442747|ensembl:ENSP00000408223|ensembl:ENST00000443308|ensembl:ENSP00000395373|ensembl:ENST00000444115|ensembl:ENSP00000407957|ensembl:ENST00000619810|ensembl:ENSP00000484992|refseq:NP_001258995.1|refseq:NP_001258996.1|refseq:NP_001258997.1|refseq:NP_001259011.1|refseq:NP_001259012.1|refseq:NP_001258994.1|refseq:XP_005265262.1|ensembl:ENSG00000164054(gene)|ensembl:ENST00000296444(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050699"(WW domain binding)|interpro:IPR026910|reactome:R-HSA-381426|reactome:R-HSA-8957275	intact:EBI-6857409(see-also)	-	-	figure legend:Fig. 3b|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:MLYJ9JCjKJoqnxTae9YhMWaWOM49606	intact-crc:71DB53761C55B009|rigid:E9m6bi20KzPvRmuH91C4Z3FjJig	true	enhanced green fluorescent protein tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P12815	uniprotkb:Q8N114	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-2115556|uniprotkb:Q69YY9|uniprotkb:Q7Z433|uniprotkb:Q8NHL9|uniprotkb:Q96MW8|uniprotkb:Q9BV58|uniprotkb:B3KW99|uniprotkb:F8W9N8|intact:EBI-28987597|ensembl:ENSP00000296444	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:shsa5_human(display_long)|uniprotkb:SHISA5(gene name)|psi-mi:SHISA5(display_short)|uniprotkb:SCOTIN(gene name synonym)|uniprotkb:Scotin(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 120(gene name synonym)|uniprotkb:PSEC0133(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6857486	intact-miscore:0.54	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:XP_011532098.1|refseq:NP_057563.3|refseq:XP_006713251.1|ensembl:ENSP00000296444|ensembl:ENST00000426002|ensembl:ENSP00000390388|ensembl:ENST00000442747|ensembl:ENSP00000408223|ensembl:ENST00000443308|ensembl:ENSP00000395373|ensembl:ENST00000444115|ensembl:ENSP00000407957|ensembl:ENST00000619810|ensembl:ENSP00000484992|refseq:NP_001258995.1|refseq:NP_001258996.1|refseq:NP_001258997.1|refseq:NP_001259011.1|refseq:NP_001259012.1|refseq:NP_001258994.1|refseq:XP_005265262.1|ensembl:ENSG00000164054(gene)|ensembl:ENST00000296444(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050699"(WW domain binding)|interpro:IPR026910|reactome:R-HSA-381426|reactome:R-HSA-8957275	intact:EBI-6857465(see-also)	-	-	figure legend:Fig. 3c|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:MLYJ9JCjKJoqnxTae9YhMWaWOM49606	intact-crc:632364A24F6ACBDD|rigid:E9m6bi20KzPvRmuH91C4Z3FjJig	true	enhanced green fluorescent protein tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P12815	uniprotkb:Q9D7I0	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-6857565|uniprotkb:Q8BJ86|uniprotkb:Q8BJ87|uniprotkb:Q8BLE9|uniprotkb:Q8K4W3|uniprotkb:Q91Z37|uniprotkb:Q9CQP5|ensembl:ENSMUSP00000026737	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:shsa5_mouse(display_long)|uniprotkb:Shisa5(gene name)|psi-mi:Shisa5(display_short)|uniprotkb:Scotin(gene name synonym)|uniprotkb:Scotin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6857612	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:NP_001271261.1|refseq:NP_080134.1|refseq:NP_080657.1|ensembl:ENSMUSG00000025647(gene)|ensembl:ENSMUST00000026737(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0050699"(WW domain binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR026910|reactome:R-MMU-381426|reactome:R-MMU-8957275	intact:EBI-6857545(see-also)	-	-	figure legend:Fig. 4|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:ZjVdG/yCMNXHIZvqC4Dd3D5LmZE10090	intact-crc:D01E28526D3A7CBE|rigid:zXJUi2ojxlkAGyg1zxtFkdkrQSA	true	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12815	uniprotkb:Q9WU78	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-641897|uniprotkb:Q3TED2|uniprotkb:O88695|uniprotkb:O89014|uniprotkb:Q8BSL8|uniprotkb:Q8R0H5|uniprotkb:Q99LR3|uniprotkb:Q9QZN8|ensembl:ENSMUSP00000035086	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:pdc6i_mouse(display_long)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)	psi-mi:"MI:0096"(pull down)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6857612	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:NP_001158149.1|refseq:NP_001158150.1|refseq:NP_035182.2|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:0043209"(myelin sheath)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q9WU78|reactome:R-MMU-5213460|reactome:R-MMU-5675482|dip:DIP-41418N	intact:EBI-6857545(see-also)	-	-	figure legend:Fig. 4|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090	intact-crc:D01E28526D3A7CBE|rigid:zXJUi2ojxlkAGyg1zxtFkdkrQSA	true	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12815	uniprotkb:Q61187	intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040	intact:EBI-1202711|ensembl:ENSMUSP00000014546	psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym)	psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0096"(pull down)	Draeby et al. (2007)	imex:IM-20894|pubmed:17889823	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6857612	intact-miscore:0.35	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG	refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center)	intact:EBI-6857545(see-also)	-	-	figure legend:Fig. 4|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/29	2014/10/16	rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090	rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090	intact-crc:D01E28526D3A7CBE|rigid:zXJUi2ojxlkAGyg1zxtFkdkrQSA	true	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12815-2	uniprotkb:Q9WU78	intact:EBI-9117858|ensembl:ENSMUSP00000152458	intact:EBI-641897|uniprotkb:Q3TED2|uniprotkb:O88695|uniprotkb:O89014|uniprotkb:Q8BSL8|uniprotkb:Q8R0H5|uniprotkb:Q99LR3|uniprotkb:Q9QZN8|ensembl:ENSMUSP00000035086	psi-mi:p12815-2(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,1(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym)	psi-mi:pdc6i_mouse(display_long)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tarabykina et al. (2000)	pubmed:10744743|imex:IM-20986	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6900302	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000222759(transcript)	refseq:NP_001158149.1|refseq:NP_001158150.1|refseq:NP_035182.2|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:0043209"(myelin sheath)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q9WU78|reactome:R-MMU-5213460|reactome:R-MMU-5675482|dip:DIP-41418N	intact:EBI-6900207(see-also)	-	-	figure legend:Fig. 5|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/07/23	2014/10/16	rogid:6eA7l1QjdIieCz6pOUr9w0bwmN410090	rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090	intact-crc:1E6B12D38D050C81|rigid:s0WAI3+eTvmPPzf0Np5O/a9cvhU	true	-	sufficient binding region:467-869	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0K8	uniprotkb:Q02487-2	intact:EBI-918926|ensembl:ENSRNOP00000043950|ensembl:ENSRNOP00000070840	intact:EBI-6900918|ensembl:ENSP00000251081	psi-mi:plak_rat(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)	psi-mi:q02487-2(display_long)|uniprotkb:DGIII(isoform synonym)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:CDHF2(gene name synonym)|uniprotkb:DSC3(gene name synonym)|uniprotkb:Cadherin family member 2(gene name synonym)|uniprotkb:Desmocollin-3(gene name synonym)|uniprotkb:Desmosomal glycoprotein II(gene name synonym)|uniprotkb:Desmosomal glycoprotein III(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gehmlich et al. (2011)	imex:IM-20978|pubmed:21220045	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6901829	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620412|refseq:NP_112309.2|refseq:XP_006247491.1|refseq:XP_006247492.1|refseq:XP_017453037.1|ensembl:ENSRNOG00000015380(gene)|ensembl:ENSRNOT00000040845(transcript)|ensembl:ENSRNOT00000089933(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|reactome:R-RNO-418990|reactome:R-RNO-5218920|reactome:R-RNO-6798695|reactome:R-RNO-6805567|reactome:R-RNO-6809371|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9013407	ensembl:ENSG00000134755(gene)|ensembl:ENST00000251081(transcript)|intact:EBI-3048545(isoform-parent)	intact:EBI-6900859(see-also)	-	-	figure legend:5B-2b|comment:"DSC2b (and the mutant)  bound only to PKP2 (Figure 5B)."|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/24	2014/10/16	rogid:yWbzwtNtLlRBegMUJ6YQyJzQpXE10116	rogid:cD7qy9ZJ5k6qj0jf5E9zzKdQ7ME9606	intact-crc:D6C226FE097566A8|rigid:MlxYShEbDlD4zJmLDzyONU76Uhg	true	-	sufficient binding region:716-847|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17302	uniprotkb:Q02487-2	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	intact:EBI-6900918|ensembl:ENSP00000251081	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:q02487-2(display_long)|uniprotkb:DGIII(isoform synonym)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:CDHF2(gene name synonym)|uniprotkb:DSC3(gene name synonym)|uniprotkb:Cadherin family member 2(gene name synonym)|uniprotkb:Desmocollin-3(gene name synonym)|uniprotkb:Desmosomal glycoprotein II(gene name synonym)|uniprotkb:Desmosomal glycoprotein III(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gehmlich et al. (2011)	imex:IM-20978|pubmed:21220045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6901218	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	ensembl:ENSG00000134755(gene)|ensembl:ENST00000251081(transcript)|intact:EBI-3048545(isoform-parent)	intact:EBI-6901142(see-also)	-	-	figure legend:6A -wt|negative:The interaction does not occur under these experimental  conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2013/07/24	2014/10/16	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	rogid:cD7qy9ZJ5k6qj0jf5E9zzKdQ7ME9606	intact-crc:D6E78196E379AE72|rigid:4uAbgGpx4n6Kp+4ASO/jnqlPtnU	true	yellow fluorescent protein tag:n-n	glutathione s tranferase tag:n-n|sufficient binding region:716-847	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P17302	uniprotkb:Q02487-2	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	intact:EBI-6900918|ensembl:ENSP00000251081	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:q02487-2(display_long)|uniprotkb:DGIII(isoform synonym)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:CDHF2(gene name synonym)|uniprotkb:DSC3(gene name synonym)|uniprotkb:Cadherin family member 2(gene name synonym)|uniprotkb:Desmocollin-3(gene name synonym)|uniprotkb:Desmosomal glycoprotein II(gene name synonym)|uniprotkb:Desmosomal glycoprotein III(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gehmlich et al. (2011)	imex:IM-20978|pubmed:21220045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6901881	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	ensembl:ENSG00000134755(gene)|ensembl:ENST00000251081(transcript)|intact:EBI-3048545(isoform-parent)	intact:EBI-6901776(see-also)	-	-	figure legend:6C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/24	2014/10/16	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	rogid:cD7qy9ZJ5k6qj0jf5E9zzKdQ7ME9606	intact-crc:832BBA26F341F65A|rigid:4uAbgGpx4n6Kp+4ASO/jnqlPtnU	true	enhanced green fluorescent protein tag:n-n|sufficient binding region:228-382	sufficient binding region:716-847|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P14270-3	uniprotkb:Q9QX74	intact:EBI-8790593	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:p14270-3(display_long)|uniprotkb:PDE3.2(isoform synonym)|uniprotkb:Pde4d(gene name)|psi-mi:Pde4d(display_short)|uniprotkb:DPDE3(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2007)	pubmed:17244609|imex:IM-21824	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8790600	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8333209(isoform-parent)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	intact:EBI-8790574(see-also)|intact:EBI-8790625(see-also)|intact:EBI-8790629(see-also)|intact:EBI-8790654(see-also)|intact:EBI-9032523(see-also)|intact:EBI-8790671(see-also)|intact:EBI-9032559(see-also)	-	-	figure legend:Fig. 4d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/09/09	2014/10/16	rogid:mW1R4L67Tt4ZcTuCkcyIp/ThU4c10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:1726C31465805894|rigid:mcEzyp4RxAAkzEUdGJqHEZ1CVFw	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14270-7	uniprotkb:Q9QX74	intact:EBI-8790607|ensembl:ENSRNOP00000062384	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:p14270-7(display_long)|uniprotkb:PDE4D6(isoform synonym)|uniprotkb:Pde4d(gene name)|psi-mi:Pde4d(display_short)|uniprotkb:DPDE3(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2007)	pubmed:17244609|imex:IM-21824	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8790605	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8333209(isoform-parent)|ensembl:ENSRNOG00000042536(gene)|ensembl:ENSRNOT00000067546(transcript)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	intact:EBI-9032559(see-also)|intact:EBI-8790654(see-also)|intact:EBI-8790574(see-also)|intact:EBI-9032523(see-also)|intact:EBI-8790671(see-also)|intact:EBI-8790629(see-also)|intact:EBI-8790625(see-also)	-	-	figure legend:Fig. 4d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/09/09	2014/10/16	rogid:4McrnjPx/1hPBZ8TjPx1+sLNkcI10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:BC53054A1CF922F0|rigid:3jpksGOmA76ky83bV2SisZNE/8g	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29590-8	uniprotkb:O14746	intact:EBI-6692454|ensembl:ENSP00000268059	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-8(display_long)|uniprotkb:PML-II(isoform synonym)|uniprotkb:TRIM19kappa(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761614	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000268059(transcript)|intact:EBI-295890(isoform-parent)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8763377(see-also)	-	-	figure legend:Figure 2 C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/09/13	2014/10/16	rogid:9wX6YVhiy58Q92O5eYXFEJQRwQ89606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:AD5AA5DBFB3FD577|rigid:5nGwyxbcq4OAGeDGO3RY0su0P7o	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P29590-9	uniprotkb:O14746	intact:EBI-6861318|ensembl:ENSP00000455612	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-9(display_long)|uniprotkb:PML-III(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761626	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000569477(transcript)|intact:EBI-295890(isoform-parent)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8763377(see-also)	-	-	figure legend:Figure 2 C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/09/13	2014/10/16	rogid:9aXmsurp88slsomTzxBdfrfEomw9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:E02BA5DBFB3F8988|rigid:uwjeQpS1O343paI9C5OYDn5jyzw	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P29590-1	uniprotkb:O14746	intact:EBI-303992|ensembl:ENSP00000268058	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-1(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-I(isoform synonym)|uniprotkb:TRIM19alpha(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761618	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000268058(transcript)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8763377(see-also)	-	-	figure legend:Figure 2 C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/09/13	2014/10/16	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:5BA3A5DBFB3D6E73|rigid:0lNnIRL8KZ78Qw1gKkcmapT5mOE	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P29590-2	uniprotkb:O14746	intact:EBI-303996|ensembl:ENSP00000395576	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-2(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-2(isoform synonym)|uniprotkb:PML-V(isoform synonym)|uniprotkb:TRIM19beta(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761622	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000435786(transcript)|uniprotkb:P29590-2(isoform-parent)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8763377(see-also)	isoform-comment:"Ref.5 (AAG50181) sequence is in conflict in position: 578:P->A. Contains a phosphoserine at position 565."	-	figure legend:Figure 2 C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/09/13	2014/10/16	rogid:+fRuye0ANEW1KaFIUBFhHCMymZ09606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:8C30A5DBFB3D8B72|rigid:5CY+zOgcrxHmGoavB1DhPQ8Zmis	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P29590-4	uniprotkb:O14746	intact:EBI-304004|ensembl:ENSP00000394642|ensembl:ENSP00000456486	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-4(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-3B(isoform synonym)|uniprotkb:PML-VI(isoform synonym)|uniprotkb:TRIM19epsilon(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761630	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000436891(transcript)|ensembl:ENST00000569965(transcript)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8763377(see-also)	isoform-comment:Contains a phosphoserine at position 518. Contains a phosphoserine at position 527. Contains a phosphoserine at position 530.	-	figure legend:Figure 2 C|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2013/09/13	2014/10/16	rogid:7Qv+/MeEQm0nHBnZdudPQApmaQk9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:9316A5DBFB3C4171|rigid:QeV7Dm2yZEHtHG4CYMyvoddI8mU	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P29590-1	uniprotkb:O14746	intact:EBI-303992|ensembl:ENSP00000268058	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-1(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-I(isoform synonym)|uniprotkb:TRIM19alpha(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761261	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000268058(transcript)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8761199(see-also)	-	-	figure legend:Figure 2 B|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/09/13	2014/10/16	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:1DB8780C2F000482|rigid:0lNnIRL8KZ78Qw1gKkcmapT5mOE	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29590-8	uniprotkb:O14746	intact:EBI-6692454|ensembl:ENSP00000268059	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-8(display_long)|uniprotkb:PML-II(isoform synonym)|uniprotkb:TRIM19kappa(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761574	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000268059(transcript)|intact:EBI-295890(isoform-parent)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8761199(see-also)	-	-	figure legend:Figure 2 B|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/09/13	2014/10/16	rogid:9wX6YVhiy58Q92O5eYXFEJQRwQ89606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:124787F3D0FC893F|rigid:5nGwyxbcq4OAGeDGO3RY0su0P7o	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O14746	uniprotkb:P29590-2	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	intact:EBI-303996|ensembl:ENSP00000395576	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:p29590-2(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-2(isoform synonym)|uniprotkb:PML-V(isoform synonym)|uniprotkb:TRIM19beta(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761476	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000435786(transcript)|uniprotkb:P29590-2(isoform-parent)	intact:EBI-8761199(see-also)	-	isoform-comment:"Ref.5 (AAG50181) sequence is in conflict in position: 578:P->A. Contains a phosphoserine at position 565."	figure legend:Figure 2 B|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/09/13	2014/10/16	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	rogid:+fRuye0ANEW1KaFIUBFhHCMymZ09606	intact-crc:EFF15C9E662430D0|rigid:5CY+zOgcrxHmGoavB1DhPQ8Zmis	true	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29590-9	uniprotkb:O14746	intact:EBI-6861318|ensembl:ENSP00000455612	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-9(display_long)|uniprotkb:PML-III(isoform synonym)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761436	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140464(gene)|ensembl:ENST00000569477(transcript)|intact:EBI-295890(isoform-parent)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8761199(see-also)	-	-	figure legend:Figure 2 B|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/09/13	2014/10/16	rogid:9aXmsurp88slsomTzxBdfrfEomw9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:43809B8217E09AF1|rigid:uwjeQpS1O343paI9C5OYDn5jyzw	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29590-4	uniprotkb:O14746	intact:EBI-304004|ensembl:ENSP00000394642|ensembl:ENSP00000456486	intact:EBI-1772203|uniprotkb:O14783|uniprotkb:Q2XS35|uniprotkb:Q8N6C3|uniprotkb:Q8NG46|uniprotkb:Q8NG38|ensembl:ENSP00000309572	psi-mi:p29590-4(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:PML-3B(isoform synonym)|uniprotkb:PML-VI(isoform synonym)|uniprotkb:TRIM19epsilon(isoform synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:tert_human(display_long)|uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:HEST2(gene name synonym)|uniprotkb:Telomerase-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oh et al. (2009)	pubmed:19567472|imex:IM-22113	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8761456	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295890(pml_human)|ensembl:ENSG00000140464(gene)|ensembl:ENST00000436891(transcript)|ensembl:ENST00000569965(transcript)	refseq:NP_001180305.1|refseq:NP_937983.2|dip:DIP-40646N|ensembl:ENSG00000164362(gene)|ensembl:ENST00000310581(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0022616"(DNA strand elongation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042635"(positive regulation of hair cycle)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0062103"(double-stranded RNA biosynthetic process)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090399"(replicative senescence)|go:"GO:0098680"(template-free RNA nucleotidyltransferase)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903620"(positive regulation of transdifferentiation)|go:"GO:1903704"(negative regulation of production of siRNA involved in RNA interference)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990572"(TERT-RMRP complex)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|interpro:IPR043502|mint:O14746|rcsb pdb:2BCK|rcsb pdb:4B18|rcsb pdb:4MNQ|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MER|rcsb pdb:5UGW|rcsb pdb:7BG9|reactome:R-HSA-171319|reactome:R-HSA-201722|rcsb pdb:5MEQ	intact:EBI-8761199(see-also)	isoform-comment:Contains a phosphoserine at position 518. Contains a phosphoserine at position 527. Contains a phosphoserine at position 530.	-	figure legend:Figure 2 B|negative:The interaction does not occur under these experimental conditions.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/09/13	2014/10/16	rogid:7Qv+/MeEQm0nHBnZdudPQApmaQk9606	rogid:jHm8Li7IWhFinYJ5gmXQJypHdUc9606	intact-crc:BB6315BAF46C5875|rigid:QeV7Dm2yZEHtHG4CYMyvoddI8mU	true	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NRW1	uniprotkb:Q02410-1	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	intact:EBI-9247467|ensembl:ENSP00000265381	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840307	intact-miscore:0.58	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	intact:EBI-8840227(see-also)	-	-	figure legend:TABLE 2 and 4|negative:The interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	intact-crc:006037DC37F8772E|rigid:r6QFdf8tRP+1cVUgjGcoAkMT21o	true	mutation:72-72|mutation:27-27	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02410-1	uniprotkb:P20340-1	intact:EBI-9247467|ensembl:ENSP00000265381	intact:EBI-8851226|ensembl:ENSP00000336850	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840304	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-8840230(see-also)	-	-	figure legend:TABLE 2 and 4|negative:The interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	intact-crc:A169B4D7617BF380|rigid:tsCS14thgI9u+0o7DOiF3/DJZfk	true	-	mutation:72-72|mutation:27-27	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NRW1	uniprotkb:Q02410-1	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	intact:EBI-9247467|ensembl:ENSP00000265381	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840419	intact-miscore:0.58	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	intact:EBI-8840370(see-also)	-	-	figure legend:Fig 2A|negative:This interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	intact-crc:4B315EF9DCDC1530|rigid:r6QFdf8tRP+1cVUgjGcoAkMT21o	true	mutation disrupting interaction:27-27|mutation:72-72|green fluorescent protein tag:?-?	glutathione s tranferase tag:n-n|binding-associated region:438-625(IPR006020)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P20340	uniprotkb:Q02410-1	intact:EBI-1052826|uniprotkb:Q5U0A8|uniprotkb:Q9UBE4|uniprotkb:A8K133|uniprotkb:Q1W5D8|uniprotkb:B7Z772|uniprotkb:F5H668|ensembl:ENSP00000336850	intact:EBI-9247467|ensembl:ENSP00000265381	psi-mi:rab6a_human(display_long)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840423	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002860.2|refseq:NP_942599.1|refseq:NP_001230648.1|refseq:NP_001230647.1|ensembl:ENSG00000175582(gene)|ensembl:ENST00000336083(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20340|rcsb pdb:1YZQ|rcsb pdb:2GIL|rcsb pdb:3BBP|rcsb pdb:3CWZ|rcsb pdb:4DKX|rcsb pdb:5LEF|reactome:R-HSA-1912420|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-39668N	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	intact:EBI-8840382(see-also)	-	-	figure legend:Fig 2A|negative:This interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	intact-crc:46D70F06857FB60E|rigid:tsCS14thgI9u+0o7DOiF3/DJZfk	true	cyan fluorescent protein tag:?-?|mutation disrupting interaction:27-27|mutation:72-72	glutathione s tranferase tag:n-n|binding-associated region:438-625(IPR006020)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02410-1	uniprotkb:P20340-1	intact:EBI-9247467|ensembl:ENSP00000265381	intact:EBI-8851226|ensembl:ENSP00000336850	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840574	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-8840525(see-also)	-	-	figure legend:Fig 3|negative:The interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/31	2014/10/16	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	intact-crc:8531DB2DD5362DD9|rigid:tsCS14thgI9u+0o7DOiF3/DJZfk	true	sufficient binding region:438-625(IPR006020)|enhanced yellow fluorescent protein tag:n-n	cyan fluorescent protein tag:c-c|mutation:72-72	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q02410-1	uniprotkb:Q9NRW1	intact:EBI-9247467|ensembl:ENSP00000265381	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	psi-mi:q02410-1(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840571	intact-miscore:0.58	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)|ensembl:ENSG00000107282(gene)|ensembl:ENST00000265381(transcript)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-8840541(see-also)	-	-	figure legend:Fig 3|negative:The interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/31	2014/10/16	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	intact-crc:F43E6813A0392304|rigid:r6QFdf8tRP+1cVUgjGcoAkMT21o	true	enhanced yellow fluorescent protein tag:n-n|sufficient binding region:438-625(IPR006020)	cyan fluorescent protein tag:c-c|mutation:72-72	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O60260	uniprotkb:Q9Y3I1-2	intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865	intact:EBI-9103020|ensembl:ENSP00000388547	psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym)	psi-mi:q9y3i1-2(display_long)|uniprotkb:FBXO7(gene name)|psi-mi:FBXO7(display_short)|uniprotkb:FBX7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Burchell et al. (2013)	pubmed:23933751|imex:IM-22049	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9102985	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N	ensembl:ENSG00000100225(gene)|ensembl:ENST00000452138(transcript)|intact:EBI-1161222(isoform-parent)	intact:EBI-9102955(see-also)	-	-	figure legend:Supp  1B|negative:The interaction does not occur under these experimental conditions.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2013/12/24	2014/10/16	rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606	rogid:McInYbvzYFKfgk+bkdGY0aAIEac9606	intact-crc:14C7273D6C3C70F0|rigid:C5xIvEAvVkmTk/rZtqlIQMSjB4E	true	flag tag:?-?	t7 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Z254	uniprotkb:Q66T02-2	intact:EBI-991162|uniprotkb:Q6GR70|uniprotkb:Q9QUQ4|ensembl:ENSRNOP00000005374	intact:EBI-9080016|ensembl:ENSMUSP00000081132	psi-mi:gipc1_rat(display_long)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:GLUT1 C-terminal-binding protein(gene name synonym)|uniprotkb:Gipc1(gene name)|psi-mi:Gipc1(display_short)|uniprotkb:Gipc(gene name synonym)|uniprotkb:Rgs19ip1(gene name synonym)|uniprotkb:Synectin(gene name synonym)	psi-mi:q66t02-2(display_long)|uniprotkb:SYX2(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2006)	imex:IM-22031|pubmed:16467373	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080014	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:68338|refseq:NP_445793.1|ensembl:ENSRNOG00000003864(gene)|ensembl:ENSRNOT00000005374(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|go:"GO:0005903"(brush border)|refseq:XP_017456861.1	intact:EBI-9079953(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000084115(transcript)	intact:EBI-9079994(see-also)	-	isoform-comment:No experimental confirmation available.	figure legend:Fig. 1d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rfpec)|taxid:10116(Rattus norvegicus epididymal fat pad endothelial cells)	-	2014/01/09	2014/10/16	rogid:uqwJJv2JErOO2NJR8CVIxCflozU10116	rogid:v0QB4Xym3Uh361M3Q13OGHMZLpE10090	intact-crc:161E5CBDCEC3B577|rigid:YjljbJrOeXM2Eau8tz5nmwcc9Ss	true	-	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q66T02-2	uniprotkb:P02563	intact:EBI-9080016|ensembl:ENSMUSP00000081132	intact:EBI-6122328|uniprotkb:Q63351	psi-mi:q66t02-2(display_long)|uniprotkb:SYX2(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym)	psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2006)	imex:IM-22031|pubmed:16467373	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080049	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9079953(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000084115(transcript)	rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961	intact:EBI-9080038(see-also)	isoform-comment:No experimental confirmation available.	-	figure legend:Fig. 1d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rfpec)|taxid:10116(Rattus norvegicus epididymal fat pad endothelial cells)	-	2014/01/09	2014/10/16	rogid:v0QB4Xym3Uh361M3Q13OGHMZLpE10090	rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116	intact-crc:7A8213AB782B486D|rigid:mkXneghlSGf7JaZlSQadjP4EQXU	true	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03372	uniprotkb:Q16881-5	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-9080418|ensembl:ENSP00000421934|ensembl:ENSP00000433425	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:q16881-5(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:TXNRD1_v1(isoform synonym)|uniprotkb:TrxR1a(isoform synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Damdimopoulos et al. (2004)	pubmed:15199063|imex:IM-22101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080432	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	ensembl:ENSG00000198431(gene)|ensembl:ENST00000503506(transcript)|ensembl:ENST00000524698(transcript)|intact:EBI-716617(isoform-parent)	intact:EBI-9080348(see-also)	-	isoform-comment:Major isoform. The N-terminus of the sequence is processed into a mature form that lacks residues Met-151 and Asn-152 at the N-terminus. Contains a N-acetylmethionine at position 1.	figure legend:Fig. 3b, Fig. 4b|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/10	2014/10/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:MDv3I5yE3FxwY8Wrfn0AjanVcpc9606	intact-crc:20BD693635451AFA|rigid:D9RMR2x2MpkpBBRCCYNEP8geffo	true	35s radiolabel:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q92731	uniprotkb:Q16881-5	intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925	intact:EBI-9080418|ensembl:ENSP00000421934|ensembl:ENSP00000433425	psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym)	psi-mi:q16881-5(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:TXNRD1_v1(isoform synonym)|uniprotkb:TrxR1a(isoform synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Damdimopoulos et al. (2004)	pubmed:15199063|imex:IM-22101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080448	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76	ensembl:ENSG00000198431(gene)|ensembl:ENST00000503506(transcript)|ensembl:ENST00000524698(transcript)|intact:EBI-716617(isoform-parent)	intact:EBI-9080386(see-also)	-	isoform-comment:Major isoform. The N-terminus of the sequence is processed into a mature form that lacks residues Met-151 and Asn-152 at the N-terminus. Contains a N-acetylmethionine at position 1.	figure legend:Fig. 3b|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/10	2014/10/16	rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606	rogid:MDv3I5yE3FxwY8Wrfn0AjanVcpc9606	intact-crc:B8C1F9770F2DAAA1|rigid:vmFVBJb2V0dZ5kX9MrSd3tex2VY	true	35s radiolabel:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q16881-5	uniprotkb:P10827	intact:EBI-9080418|ensembl:ENSP00000421934|ensembl:ENSP00000433425	intact:EBI-286285|uniprotkb:P21205|uniprotkb:Q8N6A1|uniprotkb:Q96H73|uniprotkb:A8K3B5|ensembl:ENSP00000264637|ensembl:ENSP00000377679	psi-mi:q16881-5(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:TXNRD1_v1(isoform synonym)|uniprotkb:TrxR1a(isoform synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)	psi-mi:tha_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:EAR7(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:ERBA1(gene name synonym)|uniprotkb:NR1A1(gene name synonym)|uniprotkb:THRA1(gene name synonym)|uniprotkb:THRA2(gene name synonym)|uniprotkb:V-erbA-related protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Damdimopoulos et al. (2004)	pubmed:15199063|imex:IM-22101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080560	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198431(gene)|ensembl:ENST00000503506(transcript)|ensembl:ENST00000524698(transcript)|intact:EBI-716617(isoform-parent)	refseq:NP_001177847.1|refseq:NP_001177848.1|refseq:NP_003241.2|refseq:NP_955366.1|dip:DIP-31452N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1NAV|rcsb pdb:2H77|rcsb pdb:2H79|rcsb pdb:3HZF|rcsb pdb:3ILZ|rcsb pdb:3JZB|rcsb pdb:4LNW|rcsb pdb:4LNX|reactome:R-HSA-383280|reactome:R-HSA-4090294|ensembl:ENSG00000126351(gene)|ensembl:ENST00000264637(transcript)|ensembl:ENST00000394121(transcript)	intact:EBI-9080549(see-also)	isoform-comment:Major isoform. The N-terminus of the sequence is processed into a mature form that lacks residues Met-151 and Asn-152 at the N-terminus. Contains a N-acetylmethionine at position 1.	-	figure legend:Fig. 4b|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/10	2014/10/16	rogid:MDv3I5yE3FxwY8Wrfn0AjanVcpc9606	rogid:u1B3u6XbEyC3OKOWr25s9qZYe4o9606	intact-crc:538E23AB80CD214B|rigid:ANF8U7z/93rN+hnElnTWGxJrDUI	true	glutathione s tranferase tag:c-c	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P03372	uniprotkb:Q16881-5	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-9080418|ensembl:ENSP00000421934|ensembl:ENSP00000433425	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:q16881-5(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:TXNRD1_v1(isoform synonym)|uniprotkb:TrxR1a(isoform synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Damdimopoulos et al. (2004)	pubmed:15199063|imex:IM-22101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9080610	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	ensembl:ENSG00000198431(gene)|ensembl:ENST00000503506(transcript)|ensembl:ENST00000524698(transcript)|intact:EBI-716617(isoform-parent)	intact:EBI-9080579(see-also)	-	isoform-comment:Major isoform. The N-terminus of the sequence is processed into a mature form that lacks residues Met-151 and Asn-152 at the N-terminus. Contains a N-acetylmethionine at position 1.	figure legend:Fig. 5c|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/10	2014/10/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:MDv3I5yE3FxwY8Wrfn0AjanVcpc9606	intact-crc:8D856C154A8E7266|rigid:D9RMR2x2MpkpBBRCCYNEP8geffo	true	green fluorescent protein tag:?-?	red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O95292-1	uniprotkb:O95292-2	intact:EBI-9350848|ensembl:ENSP00000417175	intact:EBI-9350855|ensembl:ENSP00000379147	psi-mi:o95292-1(display_long)|uniprotkb:VAP-B(isoform synonym)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:o95292-2(display_long)|uniprotkb:VAP-C(isoform synonym)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kukihara et al. (2009)	pubmed:19515777|imex:IM-25931	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9350862	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1188298(isoform-parent)|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)	intact:EBI-1188298(isoform-parent)|ensembl:ENSG00000124164(gene)|ensembl:ENST00000395802(transcript)	intact:EBI-9250869(see-also)	-	-	figure legend:Fig 1|negative:The interaction does not occur under   these experimental conditions.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/03/03	2014/10/16	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	rogid:x/qDU3YAfG6ixWJ9tcpDyZwWBqE9606	intact-crc:C0358C80E7AB68E4|rigid:/uyZRX6z4nxSoW74Whj7ZdfY/5I	true	sufficient binding region:71-242|glu tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9P0L0	uniprotkb:O95292-2	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	intact:EBI-9350855|ensembl:ENSP00000379147	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:o95292-2(display_long)|uniprotkb:VAP-C(isoform synonym)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kukihara et al. (2009)	pubmed:19515777|imex:IM-25931	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9350887	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	intact:EBI-1188298(isoform-parent)|ensembl:ENSG00000124164(gene)|ensembl:ENST00000395802(transcript)	intact:EBI-9250881(see-also)	-	-	figure legend:Fig 1|negative:The interaction does not occur under these experimental conditions.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/03/03	2014/10/16	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rogid:x/qDU3YAfG6ixWJ9tcpDyZwWBqE9606	intact-crc:79373BC61AC5A92E|rigid:Pos+PyKIVyAFC8btUpK3mFNMc14	true	glu tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29994	uniprotkb:P54256-1	intact:EBI-8614640|intact:MINT-5026585|uniprotkb:Q62869	intact:EBI-994549	psi-mi:itpr1_rat(display_long)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)	psi-mi:p54256-1(display_long)|uniprotkb:Long(isoform synonym)|uniprotkb:Hap1(gene name)|psi-mi:Hap1(display_short)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (2003)	pubmed:12873381|imex:IM-23002	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9674298	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001666"(response to hypoxia)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0016358"(dendrite development)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:0044325"(transmembrane transporter binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|rcsb pdb:3JAV|rcsb pdb:3T8S|rcsb pdb:3UJ0|rcsb pdb:3UJ4|rcsb pdb:6MU1|rcsb pdb:6MU2|rcsb pdb:7LHE|rcsb pdb:7LHF|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-381676|reactome:R-RNO-418457|reactome:R-RNO-5578775|reactome:R-RNO-983695|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|refseq:NP_001257526.1|rgd:2933|mint:P29994|dip:DIP-29715N	intact:EBI-994539(hap1_rat)	intact:EBI-9674273(see-also)	comment:mint|function:Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate	-	figure legend:1B|negative:The interaction does not occur under these experimental conditions.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/07/18	2014/10/16	rogid:L1I4Symxn2ABLg8esgd/caebF5810116	rogid:CHICvXtJfygpsqLcMZhgWS7+iqc10116	intact-crc:4CBC6E8B8A1A37DB|rigid:GukE9NFhrAq8eAZFsN84nm1PcV8	true	sufficient binding region:2591-2750	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75952-1	uniprotkb:P49841	intact:EBI-10898504|ensembl:ENSP00000431142|ensembl:ENSP00000432870|ensembl:ENSP00000483621	intact:EBI-373586|uniprotkb:Q9BWH3|uniprotkb:Q9UL47|uniprotkb:D3DN89|ensembl:ENSP00000264235	psi-mi:o75952-1(display_long)|uniprotkb:CABYR(gene name)|psi-mi:CABYR(display_short)|uniprotkb:CBP86(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Calcium-binding protein 86(gene name synonym)|uniprotkb:Cancer/testis antigen 88(gene name synonym)|uniprotkb:Fibrousheathin II(gene name synonym)|uniprotkb:Fibrousheathin-2(gene name synonym)|uniprotkb:Testis-specific calcium-binding protein CBP86(gene name synonym)	psi-mi:gsk3b_human(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hsu et al. (2005)	imex:IM-25005|pubmed:15752768	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900933	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154040(gene)|ensembl:ENST00000463087(transcript)|ensembl:ENST00000486759(transcript)|ensembl:ENST00000621648(transcript)|intact:EBI-10898454(isoform-parent)	refseq:NP_001139628.1|refseq:NP_002084.2|ensembl:ENSG00000082701(gene)|ensembl:ENST00000264235(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006983"(ER overload response)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|rcsb pdb:2JDO|rcsb pdb:2JDR|rcsb pdb:2JLD|rcsb pdb:2O5K|rcsb pdb:2OW3|rcsb pdb:2UW9|rcsb pdb:2X39|rcsb pdb:2XH5|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3DU8|rcsb pdb:3E87|rcsb pdb:3E88|rcsb pdb:3E8D|rcsb pdb:3F7Z|rcsb pdb:3F88|rcsb pdb:3GB2|rcsb pdb:3I4B|rcsb pdb:3L1S|rcsb pdb:3M1S|rcsb pdb:3MV5|rcsb pdb:3OW4|rcsb pdb:3PUP|rcsb pdb:3Q3B|rcsb pdb:3QKK|rcsb pdb:3SAY|rcsb pdb:3SD0|rcsb pdb:3ZDI|rcsb pdb:3ZRK|rcsb pdb:3ZRL|rcsb pdb:3ZRM|rcsb pdb:4ACC|rcsb pdb:4ACD|rcsb pdb:4ACG|rcsb pdb:4ACH|rcsb pdb:4AFJ|rcsb pdb:4B7T|rcsb pdb:4DIT|rcsb pdb:4EKK|rcsb pdb:4IQ6|rcsb pdb:4J1R|rcsb pdb:4PTE|rcsb pdb:4PTG|rcsb pdb:5F94|rcsb pdb:5F95|rcsb pdb:5HLN|rcsb pdb:5HLP|rcsb pdb:5K5N|rcsb pdb:5KPK|rcsb pdb:5KPL|rcsb pdb:5KPM|rcsb pdb:5OY4|rcsb pdb:5T31|rcsb pdb:6B8J|rcsb pdb:6BUU|rcsb pdb:6GJO|rcsb pdb:6GN1|rcsb pdb:6H0U|rcsb pdb:6HK3|rcsb pdb:6HK4|rcsb pdb:6HK7|rcsb pdb:6NPZ|rcsb pdb:6TCU|rcsb pdb:6V6L|rcsb pdb:6Y9R|rcsb pdb:6Y9S|rcsb pdb:7B6F|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198323|reactome:R-HSA-3371453|reactome:R-HSA-399956|reactome:R-HSA-4641262|reactome:R-HSA-5250924|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5674400|reactome:R-HSA-75815|reactome:R-HSA-8939902|rcsb pdb:4J71|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4PTC|reactome:R-HSA-9682706|reactome:R-HSA-9683610|reactome:R-HSA-9694631|reactome:R-HSA-9694686|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019082"(viral protein processing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034452"(dynactin binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048156"(tau protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106027"(neuron projection organization)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:P49841|rcsb pdb:1GNG|rcsb pdb:1H8F|rcsb pdb:1I09|rcsb pdb:1J1B|rcsb pdb:1J1C|rcsb pdb:1O6K|rcsb pdb:1O6L|rcsb pdb:1O9U|rcsb pdb:1PYX|rcsb pdb:1Q3D|rcsb pdb:1Q3W|rcsb pdb:1Q41|rcsb pdb:1Q4L|rcsb pdb:1Q5K|rcsb pdb:1R0E|rcsb pdb:1UV5|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-878N	intact:EBI-10898666(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	figure legend:Fig. 3A|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/07	2015/07/13	rogid:64WTKl4YcRJZDlxroCpoHRKmXDo9606	rogid:dhXyRv7fPByw6we1Rbmh8pYS05o9606	rigid:UYzuKlYtqe/zW3LrcR5Sj629zZc	true	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75952-1	uniprotkb:P49841	intact:EBI-10898504|ensembl:ENSP00000431142|ensembl:ENSP00000432870|ensembl:ENSP00000483621	intact:EBI-373586|uniprotkb:Q9BWH3|uniprotkb:Q9UL47|uniprotkb:D3DN89|ensembl:ENSP00000264235	psi-mi:o75952-1(display_long)|uniprotkb:CABYR(gene name)|psi-mi:CABYR(display_short)|uniprotkb:CBP86(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Calcium-binding protein 86(gene name synonym)|uniprotkb:Cancer/testis antigen 88(gene name synonym)|uniprotkb:Fibrousheathin II(gene name synonym)|uniprotkb:Fibrousheathin-2(gene name synonym)|uniprotkb:Testis-specific calcium-binding protein CBP86(gene name synonym)	psi-mi:gsk3b_human(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hsu et al. (2005)	imex:IM-25005|pubmed:15752768	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10901155	intact-miscore:0.51	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154040(gene)|ensembl:ENST00000463087(transcript)|ensembl:ENST00000486759(transcript)|ensembl:ENST00000621648(transcript)|intact:EBI-10898454(isoform-parent)	refseq:NP_001139628.1|refseq:NP_002084.2|ensembl:ENSG00000082701(gene)|ensembl:ENST00000264235(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006983"(ER overload response)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|rcsb pdb:2JDO|rcsb pdb:2JDR|rcsb pdb:2JLD|rcsb pdb:2O5K|rcsb pdb:2OW3|rcsb pdb:2UW9|rcsb pdb:2X39|rcsb pdb:2XH5|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3DU8|rcsb pdb:3E87|rcsb pdb:3E88|rcsb pdb:3E8D|rcsb pdb:3F7Z|rcsb pdb:3F88|rcsb pdb:3GB2|rcsb pdb:3I4B|rcsb pdb:3L1S|rcsb pdb:3M1S|rcsb pdb:3MV5|rcsb pdb:3OW4|rcsb pdb:3PUP|rcsb pdb:3Q3B|rcsb pdb:3QKK|rcsb pdb:3SAY|rcsb pdb:3SD0|rcsb pdb:3ZDI|rcsb pdb:3ZRK|rcsb pdb:3ZRL|rcsb pdb:3ZRM|rcsb pdb:4ACC|rcsb pdb:4ACD|rcsb pdb:4ACG|rcsb pdb:4ACH|rcsb pdb:4AFJ|rcsb pdb:4B7T|rcsb pdb:4DIT|rcsb pdb:4EKK|rcsb pdb:4IQ6|rcsb pdb:4J1R|rcsb pdb:4PTE|rcsb pdb:4PTG|rcsb pdb:5F94|rcsb pdb:5F95|rcsb pdb:5HLN|rcsb pdb:5HLP|rcsb pdb:5K5N|rcsb pdb:5KPK|rcsb pdb:5KPL|rcsb pdb:5KPM|rcsb pdb:5OY4|rcsb pdb:5T31|rcsb pdb:6B8J|rcsb pdb:6BUU|rcsb pdb:6GJO|rcsb pdb:6GN1|rcsb pdb:6H0U|rcsb pdb:6HK3|rcsb pdb:6HK4|rcsb pdb:6HK7|rcsb pdb:6NPZ|rcsb pdb:6TCU|rcsb pdb:6V6L|rcsb pdb:6Y9R|rcsb pdb:6Y9S|rcsb pdb:7B6F|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198323|reactome:R-HSA-3371453|reactome:R-HSA-399956|reactome:R-HSA-4641262|reactome:R-HSA-5250924|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5674400|reactome:R-HSA-75815|reactome:R-HSA-8939902|rcsb pdb:4J71|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4PTC|reactome:R-HSA-9682706|reactome:R-HSA-9683610|reactome:R-HSA-9694631|reactome:R-HSA-9694686|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019082"(viral protein processing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034452"(dynactin binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048156"(tau protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106027"(neuron projection organization)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:P49841|rcsb pdb:1GNG|rcsb pdb:1H8F|rcsb pdb:1I09|rcsb pdb:1J1B|rcsb pdb:1J1C|rcsb pdb:1O6K|rcsb pdb:1O6L|rcsb pdb:1O9U|rcsb pdb:1PYX|rcsb pdb:1Q3D|rcsb pdb:1Q3W|rcsb pdb:1Q41|rcsb pdb:1Q4L|rcsb pdb:1Q5K|rcsb pdb:1R0E|rcsb pdb:1UV5|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-878N	intact:EBI-10898666(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	negative:The interaction does not occur under these experimental conditions.|figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/07	2016/02/11	rogid:64WTKl4YcRJZDlxroCpoHRKmXDo9606	rogid:dhXyRv7fPByw6we1Rbmh8pYS05o9606	rigid:UYzuKlYtqe/zW3LrcR5Sj629zZc	true	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVV9	uniprotkb:Q9NUQ8	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463877	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16432406(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:z3DCG+LS3ZkLK7CT5jMtr1cjZUE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z645	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16432404	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z645_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463861	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0005524"(ATP binding)|interpro:IPR003439(ABC transporter-like)|interpro:IPR027417|entrezgene/locuslink:55324(identity)	intact:EBI-16429865(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:LUXhV0mfHbsf8mpOg/NiZs9wjgY9606	rigid:fBvZehgUFGbuAJOfeOCPumeHL2k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:Q9NUQ8	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463909	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16434200(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:UAIzPgFd55gU0U/qzKLjthwbCrc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q9NUQ8	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463925	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16435052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:H84lLCCKKriRrGaEaXl3Rgy5Y8A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q8NC06-3	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463941	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:a1jKG0mAeoqOuB6wRWdfZfGkWyY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:A0A0S2Z5W7	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16439276	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463957	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:kuBqfD3GDDtoLp2m6E9muMgj7qQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q8NC06	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463976	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:pMWfy772sh+KNDjkDk/vu8Uopmw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:Q8NC06-3	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463992	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:fHyscIUKPzE5Pmb9q0Ks4YU66Y4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:A0A0S2Z5W7	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-16439276	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464008	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:p3F+p9dQoeO/9dhRV/qA/E+G66w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:Q8NC06	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464024	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:wa1KZ4o42ubKnhyIhbRnHOzwcu0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:Q8NC06-3	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464040	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:Y2WnEM4IXKqL0lIun0e+UYGIVcM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z5W7	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16439276	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464056	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:34E8NEbJzAcYHMoD4f8LjJWco/Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:Q8NC06	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464072	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:4lVHE43HkhHsQPGeBgIXg2Ag/bM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:Q8NC06-3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464088	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:8u90uFjZeSf3NTigJAs3LmQzpko	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5W7	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16439276	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464104	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:WupXLsT/fqjlN0zVQVSY86SYrTM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:Q8NC06	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464120	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:4tUNKovV1oeDpJfUCGYPxQWIl8Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8NC06-3	intact:EBI-16439278	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464136	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16439289(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:okrjLyPD+lP7YCJ3ndkHWHncgxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8NC06	intact:EBI-16439278	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464152	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16439289(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:fovy9MT8NydHLCiJx3MlDPu1i6o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q9NUQ8	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463893	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16433714(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:z6SDo5ZJlomDoVXTHLU51VWV2SQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50542-3	uniprotkb:Q9ULJ7-2	intact:EBI-12181987|ensembl:ENSP00000266564|ensembl:ENSP00000500230	intact:EBI-12239063|ensembl:ENSP00000425355	psi-mi:p50542-3(display_long)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:PXR1(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:Peroxisome receptor 1(gene name synonym)	psi-mi:q9ulj7-2(display_long)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)|uniprotkb:KIAA1223(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464332	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-597835(isoform-parent)|uniprotkb:P50542-3(isoform-parent)|ensembl:ENSG00000139197(gene)|ensembl:ENSG00000288217(gene)|ensembl:ENST00000266564(transcript)|ensembl:ENST00000672776(transcript)|entrezgene/locuslink:5830(identity)	intact:EBI-5653671(isoform-parent)|uniprotkb:Q9ULJ7-2(isoform-parent)|ensembl:ENSG00000151458(gene)|ensembl:ENST00000515641(transcript)|entrezgene/locuslink:57182(identity)	intact:EBI-16433395(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:HHmRC1+icpDic4lf7z1DLsXG/gY9606	rogid:vF7ybJTcu6xrDedqEvvMz+15f3Y9606	rigid:jzZZwZ6yey6fym6J4qhv8p0XJrk	true	-	sufficient binding region:508-1250	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y4X0	uniprotkb:Q6FHY5	intact:EBI-8583355|ensembl:ENSP00000262844|uniprotkb:Q8WX22|intact:MINT-3086664|uniprotkb:Q5JYV9|uniprotkb:Q6P9D8|uniprotkb:Q9UIQ8	intact:EBI-16439278	psi-mi:ammr1_human(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464316	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101935(gene)|ensembl:ENST00000262844(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|interpro:IPR002733(AMMECR1)|interpro:IPR023473|interpro:IPR027485|interpro:IPR036071|mint:Q9Y4X0|refseq:NP_001020751.1|refseq:NP_056180.1|refseq:NP_001165160.1|entrezgene/locuslink:9949(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	intact:EBI-16439299(see-also)	comment:mint|comment:homomint|function:"Defects in AMMECR1 may be a cause of AMME complex [MIM:300194]; also known as Alport syndrome with mental retardation, midface hypoplasia and elliptocytosis. The AMME complex is a contiguous gene deletion syndrome"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:epeJrGQt5CbnPII1/FSttS0KzwE9606	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rigid:JRTxJMggk5NoA0L3DkjM6f4vA6c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95967	uniprotkb:Q9Y4X0-3	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	intact:EBI-12823597|ensembl:ENSP00000361129	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:q9y4x0-3(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464300	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	uniprotkb:Q9Y4X0-3(isoform-parent)|ensembl:ENSG00000101935(gene)|ensembl:ENST00000372059(transcript)|intact:EBI-8583355(isoform-parent)|entrezgene/locuslink:9949(identity)	intact:EBI-16433227(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:lLHOM38DC5g4w13Mv5lvL9Ci6Ec9606	rigid:p+gCaNkGJbBQAk96n6i3aYaUncI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9Y4X0-3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-12823597|ensembl:ENSP00000361129	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:q9y4x0-3(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464284	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	uniprotkb:Q9Y4X0-3(isoform-parent)|ensembl:ENSG00000101935(gene)|ensembl:ENST00000372059(transcript)|intact:EBI-8583355(isoform-parent)|entrezgene/locuslink:9949(identity)	intact:EBI-16432098(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:lLHOM38DC5g4w13Mv5lvL9Ci6Ec9606	rigid:ckur0mjrtKfJI7kWjGEHJY+zBrc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P31749	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464268	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|entrezgene/locuslink:207(identity)	intact:EBI-16440828(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	rigid:ruA0QdGBkyEQDYPkkYEF4UTqqP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:P31749	-	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464252	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|entrezgene/locuslink:207(identity)	intact:EBI-16430472(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	rigid:inJCrqJY5vATY8nElu6HXfZwBCY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P31323	uniprotkb:A0A0S2Z5A1	intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9	intact:EBI-16464200	psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short)	psi-mi:a0a0s2z5a1_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464235	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N|entrezgene/locuslink:5577(identity)	go:"GO:0016301"(kinase activity)|entrezgene/locuslink:11216(identity)	intact:EBI-16431706(see-also)|intact:EBI-16431721(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606	rogid:xFdTRYl8qw6Ue2e94+e/kOyic3A9606	rigid:5KO+2BTLTOEa6bqNXOG+9D/snAI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z551	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16431716	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z551_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464219	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR037719|entrezgene/locuslink:11216(identity)	intact:EBI-16428928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:O6Li2aTpDpFy7i6Ia/aZ/+E95iE9606	rigid:rUft2z4F9+7j93SKFlsHZk8UPNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z5A1	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16464200	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z5a1_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464203	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0016301"(kinase activity)|entrezgene/locuslink:11216(identity)	intact:EBI-16428928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:xFdTRYl8qw6Ue2e94+e/kOyic3A9606	rigid:VghsukR1voK/uKzmq639Jx44fks	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NPC6	uniprotkb:A0A0S2Z3G1	intact:EBI-746712|uniprotkb:O43415|uniprotkb:Q9HB92|ensembl:ENSP00000306997	intact:EBI-16430749	psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym)	psi-mi:a0a0s2z3g1_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464184	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057683.1|ensembl:ENSG00000172399(gene)|ensembl:ENST00000307128(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003779"(actin binding)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031433"(telethonin binding)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051373"(FATZ binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|entrezgene/locuslink:51778(identity)	entrezgene/locuslink:81(identity)	intact:EBI-16439028(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606	rogid:cBkc6vvPxaFNKnw/GZkKFkGYW5I9606	rigid:1Rmf3VjG47s27Au2CKav4P+m0fc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:O43707	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464168	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N|entrezgene/locuslink:81(identity)	intact:EBI-16430751(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rigid:D/3niI5MABckYB1EwQvY8KlKoWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z4X7	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16464351	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z4x7_human(display_long)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464354	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR026739|entrezgene/locuslink:8546(identity)	intact:EBI-16438960(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:kjlUsukeYVoZcSb+7MoA5pV5ilg9606	rigid:zJXW/f799yyXUhbV4GUccfGVtbw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14613	intact:EBI-16464370	intact:EBI-3438291|uniprotkb:Q9UNS0|uniprotkb:B2RD85|ensembl:ENSP00000279249|ensembl:ENSP00000431660	-	psi-mi:borg1_human(display_long)|uniprotkb:CDC42EP2(gene name)|psi-mi:CDC42EP2(display_short)|uniprotkb:BORG1(gene name synonym)|uniprotkb:CEP2(gene name synonym)|uniprotkb:Binder of Rho GTPases 1(gene name synonym)	psi-mi:"ccsb isoform id: arhgap26_2"(display_short)|psi-mi:EBI-16464370(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464373	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006770.1|ensembl:ENSG00000149798(gene)|ensembl:ENST00000279249(transcript)|ensembl:ENST00000533419(transcript)|go:"GO:0001515"(opioid peptide activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR017363(Cdc42 effector protein 2)|interpro:IPR029273|reactome:R-HSA-5687128|reactome:R-HSA-9013148|reactome:R-HSA-9013406|refseq:XP_016872583.1|entrezgene/locuslink:10435(identity)	entrezgene/locuslink:23092(identity)	intact:EBI-16430972(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9oBDq+/9RNfIIl3yJWKUaxKelcs9606	rogid:RizkcONMrxJVxr6OeCJ46Hx8tKU9606	rigid:ATcgQ0tOMWLdWgg+VgHH9OHdT7o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:A0A0S2Z543	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-16464389	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:a0a0s2z543_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464398	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR035899|entrezgene/locuslink:22899(identity)	intact:EBI-16434808(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:g+l8vXDSIS++OznFBOdMJnkI30Q9606	rigid:xMFhNM1fWEHcAnUpz3DL9m6rQrk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P41212	uniprotkb:O15169	intact:EBI-1372759|uniprotkb:A3QVP6|uniprotkb:Q9UMF6|uniprotkb:Q9UMF7|uniprotkb:Q9UMG0|uniprotkb:A8K076|ensembl:ENSP00000379658	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:etv6_human(display_long)|uniprotkb:ETS translocation variant 6(gene name synonym)|uniprotkb:ETS-related protein Tel1(gene name synonym)|uniprotkb:ETV6(gene name)|psi-mi:ETV6(display_short)|uniprotkb:TEL(gene name synonym)|uniprotkb:TEL1(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464414	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001978.1|dip:DIP-17028N|ensembl:ENSG00000139083(gene)|ensembl:ENST00000396373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007296"(vitellogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0097152"(mesenchymal cell apoptotic process)|interpro:IPR000418(Ets)|rcsb pdb:5L0P|rcsb pdb:7JU2|rcsb pdb:7N1O|rcsb pdb:7N2B|reactome:R-HSA-9673768|reactome:R-HSA-9703465|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P41212|rcsb pdb:1JI7|rcsb pdb:1LKY|rcsb pdb:2DAO|rcsb pdb:2QAR|rcsb pdb:2QB0|rcsb pdb:2QB1|entrezgene/locuslink:2120(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16430351(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ekItHLbEk2Expb+mR7jHa6dPBo89606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:Up2GwGxvAWYZ3lN0ev9SV/BX8vA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:A0A0S2Z4M1	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-16429430	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464430	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16435952(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:p5u4NP8iUvjq1AqyH2ZFVedYWZc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14596-2	uniprotkb:O15169	intact:EBI-11081753|ensembl:ENSP00000467816	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q14596-2(display_long)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464446	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742698(isoform-parent)|ensembl:ENSG00000188554(gene)|ensembl:ENST00000589872(transcript)|uniprotkb:Q14596-2(isoform-parent)|entrezgene/locuslink:4077(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16437295(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KrZKoabpN1yOvD3Bt6+CCN9Wv5g9606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:kRH7pDWAN2cnIuUQGo5+hm9S0kU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96C92-2	uniprotkb:O15169	intact:EBI-10178036|ensembl:ENSP00000298537	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q96c92-2(display_long)|uniprotkb:ENTR1(gene name)|psi-mi:ENTR1(display_short)|uniprotkb:Antigen NY-CO-3(gene name synonym)|uniprotkb:SDCCAG3(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 3(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464462	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165689(gene)|ensembl:ENST00000298537(transcript)|intact:EBI-717093(isoform-parent)|uniprotkb:Q96C92-2(isoform-parent)|entrezgene/locuslink:10807(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16437475(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U/LI/NOqf74lz75tLcsSMQJAAnE9606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:HVECZLCPSZg03L8BOjsYWr56/IY	true	sufficient binding region:59-412	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96K21-3	uniprotkb:A0A0S2Z4M1	intact:EBI-10187928|ensembl:ENSP00000299173	intact:EBI-16429430	psi-mi:q96k21-3(display_long)|uniprotkb:ZFYVE19(gene name)|psi-mi:ZFYVE19(display_short)|uniprotkb:ANCHR(gene name synonym)|uniprotkb:MLL partner containing FYVE domain(gene name synonym)|uniprotkb:MPFYVE(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 19(gene name synonym)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464481	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166140(gene)|ensembl:ENST00000299173(transcript)|intact:EBI-6448240(isoform-parent)|entrezgene/locuslink:84936(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16439174(see-also)	isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 286.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9uSIHmzDgn4qCPE8iSmYVruIUgY9606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:F/6xO2n3U5i58emI0+yzmjvOSY0	true	sufficient binding region:76-403	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:A0A0S2Z4M1	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-16429430	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464500	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16440624(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:EWPqB4NXOGu6G8E/SIvjn/vUBRk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z3F5	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16464516	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z3f5_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:hCG_30265(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464519	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0051087"(chaperone binding)|interpro:IPR029071|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR039773|entrezgene/locuslink:573(identity)	intact:EBI-16429885(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:gGnYMRMOEGnL3NKQfvuAHRMvIS49606	rigid:T833yVID2/ZZX1lu8rLm1fK2fpI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P11142	uniprotkb:A0A0S2Z3F5	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	intact:EBI-16464516	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:a0a0s2z3f5_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:hCG_30265(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464535	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|entrezgene/locuslink:3312(identity)	go:"GO:0051087"(chaperone binding)|interpro:IPR029071|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR039773|entrezgene/locuslink:573(identity)	intact:EBI-16435304(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:gGnYMRMOEGnL3NKQfvuAHRMvIS49606	rigid:oe9lFbF+bMDhuR65mxgXnhpm/8A	true	sufficient binding region:61-646	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	uniprotkb:E9PJI6	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464554	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:Riu0x0QOlmHVjtKcbfq0kNfFqfs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	intact:EBI-16431359	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	-	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464571	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:0AsA1HYSt8wxzPgsWXtUDNKLQ5k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	uniprotkb:A0A0S2Z5G4	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	intact:EBI-16429704	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464588	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:54sfxAW+hFPcqDNjvDPKm3ecPak	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:E9PJI6	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464605	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:p30fRFIYCMlacTWa9gRsmYqWS6k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16431359	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464621	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:FEqP6w0nijw+nAuN7FKTxG6NQHA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:Q8N9N5-7	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16429296|ensembl:ENSP00000444352	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:q8n9n5-7(display_long)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEND1(gene name synonym)|uniprotkb:SMAR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464637	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000538234(transcript)|intact:EBI-744695(isoform-parent)|entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	isoform-comment:No experimental confirmation available.	comment:"Evidence for isoform CCSB isoform ID: BANP_4 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:t2jbYP8LrjN6XFcera/qV+cHUNg9606	rigid:lo+yzkwx10cVCUSMrRozAnN7R4Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3K3	uniprotkb:E9PJI6	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464653	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|entrezgene/locuslink:23126(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429761(see-also)|intact:EBI-16429771(see-also)|intact:EBI-16429781(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:bFzMxsTxvIvA0ZIpzqnUmIe6GSc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96QF0-7	uniprotkb:E9PJI6	intact:EBI-11984839|ensembl:ENSP00000368092	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q96qf0-7(display_long)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464689	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96QF0-7(isoform-parent)|intact:EBI-747844(isoform-parent)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000378815(transcript)|entrezgene/locuslink:117177(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429803(see-also)|intact:EBI-16429813(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AbUJj24KJUXc9MOj/FSx+ogmdfI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:qVwxbL/qtc1gHwsI0/sInluUTQY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3K3	intact:EBI-16431359	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715	-	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464671	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|entrezgene/locuslink:23126(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429761(see-also)|intact:EBI-16429771(see-also)|intact:EBI-16429781(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ii6NNBDdNySCT3D570TmdMrBs0w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	uniprotkb:E9PJI6	intact:EBI-5237510|ensembl:ENSP00000354492	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465007	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ClJeMYYas/DLNOW6abFOHNGUUl8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	intact:EBI-16431359	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	-	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464988	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16433516(see-also)|intact:EBI-16433526(see-also)|intact:EBI-16433536(see-also)|intact:EBI-16433546(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:1iZBVaBf2RHTlnMFCcxEhlhqYko	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:E9PJI6	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464969	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16433516(see-also)|intact:EBI-16433526(see-also)|intact:EBI-16433536(see-also)|intact:EBI-16433546(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:8CCbSDS1Vxm+048AznupzQXW3ds	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	intact:EBI-16431359	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	-	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464950	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16433313(see-also)|intact:EBI-16433323(see-also)|intact:EBI-16433333(see-also)|intact:EBI-16433343(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:C11XXi5gd+6AQlZieuOxrg4LAWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:E9PJI6	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464931	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16433313(see-also)|intact:EBI-16433323(see-also)|intact:EBI-16433333(see-also)|intact:EBI-16433343(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:tyxCVy+vKP0nDSYB+PgosCXTvtI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:A0A0S2Z5G4	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16429704	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464915	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:f1EpXrYmhkBVEXbnKjXen6vO60g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:B4DE54	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16429313	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464899	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:QBD3Rqe4ftOZNMVpav4O3bmxrMk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	intact:EBI-16431359	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	-	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464883	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:XLlpUR0/1u2hL1cfaiKN/5Hit8c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:E9PJI6	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464867	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:NqMj4Xt9CQGHwNDdHWPPY5E2sLI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:E9PJI6	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464847	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16431349(see-also)|intact:EBI-16431361(see-also)|intact:EBI-16431371(see-also)|intact:EBI-16431381(see-also)|intact:EBI-16431391(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:w3JmXLU7ivVJwtXtIg0LThX7p7s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:A0A0S2Z5G4	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-16429704	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464831	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:qKyzV4pxzBmU3GbxYqtRnVRMXy0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	intact:EBI-16431359	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	-	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464815	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:rkLtDvBC2R7FVyBI2um7pITV6mo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:E9PJI6	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464799	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:g16T9KXTyDoEEMofKcOSVtZYRzU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	intact:EBI-16431359	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	-	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464781	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16430502(see-also)|intact:EBI-16430512(see-also)|intact:EBI-16430522(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:5e1vuQqfY8tSCso7BRxHnZ3FlfE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96QF0-7	intact:EBI-16431359	intact:EBI-11984839|ensembl:ENSP00000368092	-	psi-mi:q96qf0-7(display_long)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464746	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96QF0-7(isoform-parent)|intact:EBI-747844(isoform-parent)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000378815(transcript)|entrezgene/locuslink:117177(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429803(see-also)|intact:EBI-16429813(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AbUJj24KJUXc9MOj/FSx+ogmdfI9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:SEfKTmI2u6xaTU/4ViZu6iZ4zkE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:E9PJI6	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464763	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16430502(see-also)|intact:EBI-16430512(see-also)|intact:EBI-16430522(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EmSSswSXRWuu4+7OZJZA2pHyy5o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16440472	intact:EBI-16431359	-	-	psi-mi:"ccsb orf id: 9576"(display_short)|psi-mi:EBI-16440472(display_long)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465540	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57573(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440474(see-also)|intact:EBI-16440484(see-also)|intact:EBI-16440494(see-also)|intact:EBI-16440534(see-also)|intact:EBI-16440544(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:x1KdEVhuKo5sZGVPBGE9eyTup9w9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:Kjl4ERNshVBdkbDxPPjV/XO6JZw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P1W5	intact:EBI-16431359	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	-	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465519	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440388(see-also)|intact:EBI-16440400(see-also)|intact:EBI-16440412(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:EpQQ8lh9BWVISt2FiFU1y/Y7Q0E	true	sufficient binding region:191-598	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:E9PJI6	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465498	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16440388(see-also)|intact:EBI-16440400(see-also)|intact:EBI-16440412(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:CwGh8gLo942BIljrssdHbGHV+Os	true	sufficient binding region:191-598	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:E9PJI6	intact:EBI-16439278	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465478	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16439329(see-also)|intact:EBI-16439339(see-also)|intact:EBI-16439349(see-also)|intact:EBI-16439359(see-also)|intact:EBI-16439369(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ZJTXeJaR2kS/7ERGf1hIvT2q9A4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF64	intact:EBI-16431359	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	-	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465456	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16439186(see-also)|intact:EBI-16439198(see-also)|intact:EBI-16439210(see-also)|intact:EBI-16439222(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:SywWL6wJwqVVQ7SwwBjdZ5K+3pU	true	sufficient binding region:479-920	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF64	uniprotkb:E9PJI6	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465434	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16439186(see-also)|intact:EBI-16439198(see-also)|intact:EBI-16439210(see-also)|intact:EBI-16439222(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:TG6CNLvch64nTfTJklVSe4Eibyw	true	sufficient binding region:479-920	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAN9	intact:EBI-16431359	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	-	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465416	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16438880(see-also)|intact:EBI-16438890(see-also)|intact:EBI-16438900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:/Ll38steqYxamkTP1HwueCufmMs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:E9PJI6	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465398	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16438880(see-also)|intact:EBI-16438890(see-also)|intact:EBI-16438900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:2/Mk2hotNFGkedZ8W815tUibD9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60479	intact:EBI-16431359	intact:EBI-3908248|uniprotkb:B3KQL6|ensembl:ENSP00000389870	-	psi-mi:dlx3_human(display_long)|uniprotkb:DLX3(gene name)|psi-mi:DLX3(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465380	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005211.1|ensembl:ENSG00000064195(gene)|ensembl:ENST00000434704(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|rcsb pdb:4XRS|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:1747(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16438402(see-also)|intact:EBI-16438412(see-also)|intact:EBI-16438422(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kU9aTRVuPjo/1OrEyWfyX4PMK9w9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:l+hOzs2ZxPgJo09uitNV34vNDRo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60479	uniprotkb:E9PJI6	intact:EBI-3908248|uniprotkb:B3KQL6|ensembl:ENSP00000389870	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:dlx3_human(display_long)|uniprotkb:DLX3(gene name)|psi-mi:DLX3(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465362	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005211.1|ensembl:ENSG00000064195(gene)|ensembl:ENST00000434704(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|rcsb pdb:4XRS|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:1747(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16438402(see-also)|intact:EBI-16438412(see-also)|intact:EBI-16438422(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kU9aTRVuPjo/1OrEyWfyX4PMK9w9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:vW37ddjzdRaaUlfle279LowFihQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:A0A0S2Z5G4	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16429704	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465345	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:d0wWL85AFpJXEeXCyz4drdP3pVk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:B4DE54	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16429313	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465328	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:6k3W8FLqpAWGYWUM4YQyc8Rt96o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	intact:EBI-16431359	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	-	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465311	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:x+oS2iSCrlYC7unbRSx9XPqvai0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:E9PJI6	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465294	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:fxjclG4s540yKAPBau19zsQUuQs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94842	intact:EBI-16431359	intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0	-	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465275	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1|entrezgene/locuslink:9878(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437830(see-also)|intact:EBI-16437840(see-also)|intact:EBI-16437850(see-also)|intact:EBI-16437860(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:bC3VjCDwZN0DROCXFITAFmHsHT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94842	uniprotkb:E9PJI6	intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465256	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1|entrezgene/locuslink:9878(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437830(see-also)|intact:EBI-16437840(see-also)|intact:EBI-16437850(see-also)|intact:EBI-16437860(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EiDWkcZNRU9NrZCdRoXvrag0oQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14192	intact:EBI-16431359	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	-	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465237	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|entrezgene/locuslink:2274(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437435(see-also)|intact:EBI-16437445(see-also)|intact:EBI-16437455(see-also)|intact:EBI-16437465(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ArVONf/tPqxkF5FnpVL0oIF91CQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14192	uniprotkb:E9PJI6	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465218	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|entrezgene/locuslink:2274(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437435(see-also)|intact:EBI-16437445(see-also)|intact:EBI-16437455(see-also)|intact:EBI-16437465(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:z+XvVjtUKkSeByz5ElLk9kPZ0+s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	uniprotkb:B4DE54	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	intact:EBI-16429313	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465201	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:Fl8GdB3MsrIP3VDT6c8M093Yi1w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	intact:EBI-16431359	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	-	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465184	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ynnEBv5/cqBJh9ZTjBhXgiqcdgU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	uniprotkb:E9PJI6	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465167	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EOu8xuF/rc7WEpcjTwn869dUJUo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	uniprotkb:B4DE54	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	intact:EBI-16429313	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465151	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:wBqtU0sX2M51v2L91qJeOjKyA+4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	intact:EBI-16431359	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	-	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465135	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:sypmBy2E5FBONvXS3MKybukBaGI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	uniprotkb:E9PJI6	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465119	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:zuMpXlWCHKcb4unxVXA++V9+CTU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:E9PJI6	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465099	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16435668(see-also)|intact:EBI-16435678(see-also)|intact:EBI-16435688(see-also)|intact:EBI-16435698(see-also)|intact:EBI-16435708(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ifGScY2hev4/H5TLPtC+jPHfVWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q02446	intact:EBI-16431359	intact:EBI-10198587|uniprotkb:Q32M52|uniprotkb:O60402|ensembl:ENSP00000222584	-	psi-mi:sp4_human(display_long)|uniprotkb:SP4(gene name)|psi-mi:SP4(display_short)|uniprotkb:SPR-1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465080	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003103.2|refseq:NP_001313472.1|ensembl:ENSP00000222584|ensembl:ENSG00000105866(gene)|ensembl:ENST00000222584(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030453|interpro:IPR036236|entrezgene/locuslink:6671(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16435380(see-also)|intact:EBI-16435390(see-also)|intact:EBI-16435400(see-also)|intact:EBI-16435410(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:DK4Of4EpByHdtSsZb3eAiOlGFNY9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:xHXnes3iVcxaHxP4otHDvAA+LIA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q02446	uniprotkb:E9PJI6	intact:EBI-10198587|uniprotkb:Q32M52|uniprotkb:O60402|ensembl:ENSP00000222584	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:sp4_human(display_long)|uniprotkb:SP4(gene name)|psi-mi:SP4(display_short)|uniprotkb:SPR-1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465061	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003103.2|refseq:NP_001313472.1|ensembl:ENSP00000222584|ensembl:ENSG00000105866(gene)|ensembl:ENST00000222584(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030453|interpro:IPR036236|entrezgene/locuslink:6671(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16435380(see-also)|intact:EBI-16435390(see-also)|intact:EBI-16435400(see-also)|intact:EBI-16435410(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:DK4Of4EpByHdtSsZb3eAiOlGFNY9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:Pd+yVoJd2HfoKZYFYSQ3L2gwAbg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	uniprotkb:A0A0S2Z5G4	intact:EBI-5237510|ensembl:ENSP00000354492	intact:EBI-16429704	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465043	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:nqkpWWaVhlIHhQqKQU6GvZxS/BM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	intact:EBI-16431359	intact:EBI-5237510|ensembl:ENSP00000354492	-	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465025	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:A//m5nsV5BKmHEWq5Cbky7XfVUQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:E9PJI6	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465560	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16440634(see-also)|intact:EBI-16440644(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:BBFTgcm3BI4aGb8Mk+DeygVLNXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LC9	uniprotkb:Q07817-2	intact:EBI-3919268|ensembl:ENSP00000346697|ensembl:ENSP00000380703|ensembl:ENSP00000453522|ensembl:ENSP00000453892|uniprotkb:Q7Z7D5|uniprotkb:Q9H7K7|uniprotkb:Q6NT30|uniprotkb:Q6P9F6|uniprotkb:Q6NT56|uniprotkb:Q7Z7D4|uniprotkb:Q2M396	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bmf_human(display_long)|uniprotkb:BMF(gene name)|psi-mi:BMF(display_short)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465594	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104081(gene)|ensembl:ENST00000354670(transcript)|ensembl:ENST00000397573(transcript)|ensembl:ENST00000561282(transcript)|ensembl:ENST00000561360(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR028192|reactome:R-HSA-111453|reactome:R-HSA-139910|refseq:NP_001003940.1|refseq:NP_001003942.1|refseq:NP_001003943.1|refseq:NP_277038.1|entrezgene/locuslink:90427(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16431439(see-also)|intact:EBI-16431451(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2i6Tua07jZ3glxnc0ruMueU/JZw9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:A1EKQaHkB59ikhPsYdlO4bbrFZk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	intact:EBI-16431359	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	-	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465577	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440634(see-also)|intact:EBI-16440644(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:zXWMX7GYzE+rYGqMrK8rI0iYhDw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92934	uniprotkb:A0A0S2Z3D2	intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040	intact:EBI-16431449	psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:a0a0s2z3d2_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Bcl-2-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465627	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400|entrezgene/locuslink:572(identity)	go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR026298|interpro:IPR020731|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020728|interpro:IPR036834|entrezgene/locuslink:598(identity)	intact:EBI-16433819(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_3 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606	rogid:3qwkOrNcTdGiBthNQHV3qpVD13s9606	rigid:WOzWuD/uK7QBBg8FJwVGoYz8Z1A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92934	uniprotkb:Q07817-2	intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465611	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400|entrezgene/locuslink:572(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16433819(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:2NTFzffv7sWgyu+aMlbuPQeksys	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WWW0-2	uniprotkb:A0A0S2Z4Q5	intact:EBI-960502|ensembl:ENSP00000462576	intact:EBI-16465731	psi-mi:q8www0-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:RAPL(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465752	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-367390(q8www0_human)|ensembl:ENSG00000266094(gene)|ensembl:ENST00000577571(transcript)|uniprotkb:Q8WWW0-2(isoform-parent)|entrezgene/locuslink:83593(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16430021(see-also)|intact:EBI-16430031(see-also)	isoform-comment:Initiator Met-1 is removed. Contains a N-acetylthreonine at position 2.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zcc13rWLmCPQVfU4D6bvIiAnIbc9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:OYpdezIR2SdeuLfywqlB4Y8InAk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C026	uniprotkb:A0A0S2Z4Q5	intact:EBI-720828|ensembl:ENSP00000298355|uniprotkb:Q92557|uniprotkb:Q96D24|uniprotkb:Q96NI4|uniprotkb:Q9C025|uniprotkb:Q9C027|uniprotkb:D3DSB7|uniprotkb:D3DSB8	intact:EBI-16465731	psi-mi:trim9_human(display_long)|uniprotkb:RING finger protein 91(gene name synonym)|uniprotkb:TRIM9(gene name)|psi-mi:TRIM9(display_short)|uniprotkb:KIAA0282(gene name synonym)|uniprotkb:RNF91(gene name synonym)|uniprotkb:Tripartite motif-containing protein 9(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM9(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465786	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100505(gene)|ensembl:ENST00000298355(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR036116|interpro:IPR043136|rcsb pdb:2DB8|rcsb pdb:7B2S|reactome:R-HSA-983168|refseq:XP_011534691.1|refseq:NP_055978.4|refseq:NP_443210.1|refseq:XP_016876434.1|entrezgene/locuslink:114088(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16431493(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cWf6NobHVvKBKNqclJsLeoJKfMw9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:umZzOXc+BSoh3FXyg6cx6pfeIZ8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:A0A0S2Z4Q5	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16465731	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465802	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:OwfhuvELWC1WlvvffUkpRIc4WXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:A0A0S2Z507	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16429247	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:a0a0s2z507_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465818	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	go:"GO:0046983"(protein dimerization activity)|interpro:IPR021977|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036047|interpro:IPR036322|entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_3 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:MFv+nq3XA7DR61lk2x4jN8sKfCw9606	rigid:HT4+0clf0EvS6FwXkeFXn0WudT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:B7Z3H4	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16429269|ensembl:ENSP00000377088	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:b7z3h4_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:hCG_1811016(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465834	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	ensembl:ENSG00000166167(gene)|ensembl:ENST00000393441(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001243785.1|entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_4 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:IbM+YU1ikaWXnOc33Set3iX0O+Q9606	rigid:augjcqPlx9PF/mNB8QjLoBzzObY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P18848	uniprotkb:A0A0S2Z4Q5	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	intact:EBI-16465731	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465850	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16434975(see-also)|intact:EBI-16434985(see-also)	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:WVl3z4HbM4ROl58XwRA3gRAw7m4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C026-5	uniprotkb:A0A0S2Z4Q5	intact:EBI-16437499|ensembl:ENSP00000353561	intact:EBI-16465731	psi-mi:q9c026-5(display_long)|uniprotkb:RING finger protein 91(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM9(gene name synonym)|uniprotkb:Tripartite motif-containing protein 9(gene name synonym)|uniprotkb:TRIM9(gene name)|psi-mi:TRIM9(display_short)|uniprotkb:KIAA0282(gene name synonym)|uniprotkb:RNF91(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465867	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100505(gene)|ensembl:ENST00000360392(transcript)|intact:EBI-720828(isoform-parent)|uniprotkb:Q9C026-5(isoform-parent)|entrezgene/locuslink:114088(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16437506(see-also)|intact:EBI-16437516(see-also)|intact:EBI-16437526(see-also)	isoform-comment:May be due to intron retention.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6t1br4sRAyAn+kB91xNFnS/ZhVc9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:ie0AUaZRWYs/blB5M4VLgTC3rU0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P18848	uniprotkb:A0A0S2Z4Q5	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	intact:EBI-16465731	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465885	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16437999(see-also)|intact:EBI-16438009(see-also)|intact:EBI-16438019(see-also)	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:WVl3z4HbM4ROl58XwRA3gRAw7m4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5Z3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16435510	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5z3_human(display_long)|uniprotkb:C6orf142(gene name)|psi-mi:C6orf142(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465903	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	interpro:IPR029331|entrezgene/locuslink:90523(identity)	intact:EBI-16435748(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: C6orf142_6 expression is provided in figureS2A."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:PfQUKaz+GBfRD1ufYrtnB7serb89606	rigid:AqbexUScQYtjqBs/sb4BSv3omcY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O76003	uniprotkb:A0A0S2Z341	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	intact:EBI-16465919	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:a0a0s2z341_human(display_long)|uniprotkb:CA9(gene name)|psi-mi:CA9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465922	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR018429|interpro:IPR023561|interpro:IPR036398|entrezgene/locuslink:768(identity)	intact:EBI-16436308(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	rogid:EghTBTX6++a4s0rZn43UQmLE2hY9606	rigid:nGdFzILF2SgFRTtJ1UCju3LACAs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P20807-4	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-11532021|ensembl:ENSP00000380384	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:p20807-4(display_long)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465938	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	intact:EBI-5655000(isoform-parent)|uniprotkb:P20807-4(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000397200(transcript)|entrezgene/locuslink:825(identity)	intact:EBI-16430534(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:6TrGg2jigHr0xYLsxBNCLjAl3J89606	rigid:zbx/WzOE/aQ1Pn576idO9YXdrRI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75410-7	uniprotkb:A0A0S2Z4Q5	intact:EBI-12007872|ensembl:ENSP00000428706	intact:EBI-16465731	psi-mi:o75410-7(display_long)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Taxin-1(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465734	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-624237(isoform-parent)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000518415(transcript)|uniprotkb:O75410-7(isoform-parent)|entrezgene/locuslink:6867(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16429237(see-also)|intact:EBI-16429259(see-also)|intact:EBI-16429286(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:l8Qbl9ca/hqZkBKqQ2v6GjaAEgk9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:Y1E2GXW8zC78AjPtjK2jUX20nuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z3I5	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16465708	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z3i5_human(display_long)|uniprotkb:BTC(gene name)|psi-mi:BTC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465715	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	go:"GO:0005154"(epidermal growth factor receptor binding)|interpro:IPR015497(Epidermal growth factor receptor ligand)|refseq:NP_001303892.1|entrezgene/locuslink:685(identity)	intact:EBI-16434559(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:e2V7UBBKhvGhrrNRn8H+4nwIV+o9606	rigid:eXcFmDhYsdGjbCuVNz60c7s5HcE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q07817-2	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465692	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16436941(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:uX21Cd9Z84JOwEn7Tevp8AddFM0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q07817	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465676	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|entrezgene/locuslink:598(identity)	intact:EBI-16436941(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_1 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rigid:349mrjMS6yPo8eQPu2qSoZiPagM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13323	uniprotkb:Q07817-2	intact:EBI-700794|uniprotkb:Q16582|uniprotkb:Q6FH93|ensembl:ENSP00000216115	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bik_human(display_long)|uniprotkb:Apoptosis inducer NBK(gene name synonym)|uniprotkb:BP4(gene name synonym)|uniprotkb:BIP1(gene name synonym)|uniprotkb:BIK(gene name)|psi-mi:BIK(display_short)|uniprotkb:NBK(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465659	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188.1|dip:DIP-928N|ensembl:ENSG00000100290(gene)|ensembl:ENST00000216115(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR020728|interpro:IPR024579|rcsb pdb:2IPE|entrezgene/locuslink:638(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16433829(see-also)|intact:EBI-16433839(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M34Yl66KzkhNSq7e3WKQMb6WDqU9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:9pFUlsrK0+X5qdQyZNT821PTDmM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WWW0-2	uniprotkb:B7Z3H4	intact:EBI-960502|ensembl:ENSP00000462576	intact:EBI-16429269|ensembl:ENSP00000377088	psi-mi:q8www0-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:RAPL(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym)	psi-mi:b7z3h4_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:hCG_1811016(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465769	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-367390(q8www0_human)|ensembl:ENSG00000266094(gene)|ensembl:ENST00000577571(transcript)|uniprotkb:Q8WWW0-2(isoform-parent)|entrezgene/locuslink:83593(identity)	ensembl:ENSG00000166167(gene)|ensembl:ENST00000393441(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001243785.1|entrezgene/locuslink:8945(identity)	intact:EBI-16430021(see-also)|intact:EBI-16430031(see-also)	isoform-comment:Initiator Met-1 is removed. Contains a N-acetylthreonine at position 2.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_4 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zcc13rWLmCPQVfU4D6bvIiAnIbc9606	rogid:IbM+YU1ikaWXnOc33Set3iX0O+Q9606	rigid:Ldmv65EjGabKFtCADqD1QeRZWZA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:A0A0S2Z535	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466123	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:a0a0s2z535_human(display_long)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466134	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:bNr8fCnUh6JVd1nweyJnl1vRq1U9606	rigid:RAHCkB0+YYLFoW7ICeJTbEGiVtk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q8IZL9-5	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466096|ensembl:ENSP00000365043	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:q8izl9-5(display_long)|uniprotkb:CDK-activating kinase p42(gene name synonym)|uniprotkb:Cell cycle-related kinase(gene name synonym)|uniprotkb:Cell division protein kinase 20(gene name synonym)|uniprotkb:Cyclin-dependent protein kinase H(gene name synonym)|uniprotkb:Cyclin-kinase-activating kinase p42(gene name synonym)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)|uniprotkb:CCRK(gene name synonym)|uniprotkb:CDCH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466104	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	intact:EBI-6128565(isoform-parent)|ensembl:ENSG00000156345(gene)|ensembl:ENST00000375883(transcript)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:8/Rfk69ifNEUfBSw6ZmO3XtVpR49606	rigid:ln15B++HH1aVtBp2Icj2CUXlMPA	true	-	sufficient binding region:1-284	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q8IZL9-3	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466072|ensembl:ENSP00000474485	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:q8izl9-3(display_long)|uniprotkb:CDK-activating kinase p42(gene name synonym)|uniprotkb:Cell cycle-related kinase(gene name synonym)|uniprotkb:Cell division protein kinase 20(gene name synonym)|uniprotkb:Cyclin-dependent protein kinase H(gene name synonym)|uniprotkb:Cyclin-kinase-activating kinase p42(gene name synonym)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)|uniprotkb:CCRK(gene name synonym)|uniprotkb:CDCH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466080	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	intact:EBI-6128565(isoform-parent)|ensembl:ENSG00000156345(gene)|ensembl:ENST00000605159(transcript)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:mzVgLqbO3Gx5NNkSScj/30Q6PkI9606	rigid:jHbYac9KDRaDIeBQjd6t/DiRLl0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q8TCZ2	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2824782|uniprotkb:B3KWG2|uniprotkb:E7EMK5|uniprotkb:A8K2D5|uniprotkb:Q9BQG9|uniprotkb:Q8TCZ0|uniprotkb:Q8TCZ1|uniprotkb:Q8TAW2|uniprotkb:A8K5R0|ensembl:ENSP00000359403|uniprotkb:B4DDL7|uniprotkb:E9PD27	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:c99l2_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)|uniprotkb:MIC2L1(gene name synonym)|uniprotkb:MIC2-like protein 1(gene name synonym)|uniprotkb:UNQ1964/PRO4486(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466056	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:XP_011529504.1|ensembl:ENSG00000102181(gene)|ensembl:ENST00000370377(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|reactome:R-HSA-202733|refseq:NP_001171737.1|refseq:NP_001229543.1|refseq:NP_113650.2|refseq:NP_604394.1|refseq:NP_604395.1|entrezgene/locuslink:83692(identity)	intact:EBI-16438188(see-also)	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:cOdUpR8H6oxHn9UfccggMMm1Z2Q9606	rigid:LBAu+8JribIhl/WWeNW/Nntefpw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:Q8TCZ2	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-2824782|uniprotkb:B3KWG2|uniprotkb:E7EMK5|uniprotkb:A8K2D5|uniprotkb:Q9BQG9|uniprotkb:Q8TCZ0|uniprotkb:Q8TCZ1|uniprotkb:Q8TAW2|uniprotkb:A8K5R0|ensembl:ENSP00000359403|uniprotkb:B4DDL7|uniprotkb:E9PD27	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:c99l2_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)|uniprotkb:MIC2L1(gene name synonym)|uniprotkb:MIC2-like protein 1(gene name synonym)|uniprotkb:UNQ1964/PRO4486(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466040	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	refseq:XP_011529504.1|ensembl:ENSG00000102181(gene)|ensembl:ENST00000370377(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|reactome:R-HSA-202733|refseq:NP_001171737.1|refseq:NP_001229543.1|refseq:NP_113650.2|refseq:NP_604394.1|refseq:NP_604395.1|entrezgene/locuslink:83692(identity)	intact:EBI-16434931(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:cOdUpR8H6oxHn9UfccggMMm1Z2Q9606	rigid:tf6rjO6yp1ZvueG+S880wOt+Y/0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:A0A0S2Z5R8	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-16434925	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466024	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16434057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:brRCihx/XTqw59QsNiqCMTTKe+E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:A0A0S2Z5R8	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-16434925	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466008	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16432790(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:P98P5AiwDt/mdctHeYlXN1mHfz8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z5R8	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16434925	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465992	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16431106(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:Frs+yUg7yJ0yHSxIQOC/JWh9uZ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P42575	uniprotkb:A0A0S2Z3I0	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	intact:EBI-16465973	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:a0a0s2z3i0_human(display_long)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465976	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207|entrezgene/locuslink:835(identity)	go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|entrezgene/locuslink:835(identity)	intact:EBI-16433486(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	rogid:ckpVZUI1KmwvIG8BejUQJBKJ5Zk9606	rigid:wo+/Z9AOwRB5k6/5zbJn1XZZ0rc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P20807-2	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-16433991|ensembl:ENSP00000183936	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:p20807-2(display_long)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:NCL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465954	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	intact:EBI-5655000(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000349748(transcript)|entrezgene/locuslink:825(identity)	intact:EBI-16430534(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:Gp5IWqWrBXlXLtZ/K/fkkGHncHc9606	rigid:NzbxgrxZr704cltpDah83mavur8	true	-	sufficient binding region:465-729	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P30279	uniprotkb:Q00535-2	intact:EBI-748789|uniprotkb:Q13955|uniprotkb:Q5U035|uniprotkb:A8K531|ensembl:ENSP00000261254|ensembl:ENSP00000502597|ensembl:ENSP00000502654	intact:EBI-16466150|ensembl:ENSP00000297518	psi-mi:ccnd2_human(display_long)|uniprotkb:CCND2(gene name)|psi-mi:CCND2(display_short)	psi-mi:q00535-2(display_long)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)|uniprotkb:CDK5-SV(isoform synonym)|uniprotkb:CDK5(gene name)|psi-mi:CDK5(display_short)|uniprotkb:CDKN5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466158	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001750.1|ensembl:ENSG00000118971(gene)|ensembl:ENST00000261254(transcript)|ensembl:ENST00000676279(transcript)|ensembl:ENST00000676411(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P30279|rcsb pdb:6EI2|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9661069|go:"GO:0005829"(cytosol)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|dip:DIP-178N|entrezgene/locuslink:894(identity)	ensembl:ENSG00000164885(gene)|ensembl:ENST00000297518(transcript)|intact:EBI-1041567(isoform-parent)|entrezgene/locuslink:1020(identity)	intact:EBI-16437667(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7DtKJiw07/E5uNvUagbYbcAo7kM9606	rogid:pxKjln6Un7Mq+4T2JOI8igx0S2E9606	rigid:4Vi5IuVIlpqvnkHKxznyiW+w2MA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:P27918	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-9038570|uniprotkb:O15134|uniprotkb:O15135|uniprotkb:O15136|uniprotkb:O75826|ensembl:ENSP00000247153|ensembl:ENSP00000380189	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:prop_human(display_long)|uniprotkb:CFP(gene name)|psi-mi:CFP(display_short)|uniprotkb:PFC(gene name synonym)|uniprotkb:Complement factor P(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466174	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	refseq:NP_001138724.1|refseq:NP_002612.1|ensembl:ENSG00000126759(gene)|ensembl:ENST00000247153(transcript)|ensembl:ENST00000396992(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006955"(immune response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR036383|rcsb pdb:1W0R|rcsb pdb:1W0S|rcsb pdb:6RUR|rcsb pdb:6RUS|rcsb pdb:6RUV|rcsb pdb:6RV6|rcsb pdb:6S08|rcsb pdb:6S0A|rcsb pdb:6S0B|rcsb pdb:6SEJ|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-6798695|reactome:R-HSA-977606|entrezgene/locuslink:5199(identity)	intact:EBI-16434712(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:XBExMxbnkfjvnV9zHMRZgxZWKaw9606	rigid:nwEQIo78bTwdV/Ok1tvCtDrSwDY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z3J3	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466190	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z3j3_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466199	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:jAqpY5lOQfTB1nAYqNwXBCHTVCk9606	rigid:zMOFtUSqyjld1BSIGh+lhsHWygU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z3G7	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466215	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z3g7_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466224	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:JvPbgQ8n9O7hA1kBCmeExmxyX149606	rigid:r5RWj0HuoNITJjrckpCBMzeQ14s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z368	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466240	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z368_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466243	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:QqkkEDwGhMlbxJz7AWZzkw7EAeo9606	rigid:SuX5f8lWsI8EFWII9A9VBF+mHv4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z3J3	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466190	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z3j3_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466259	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:jAqpY5lOQfTB1nAYqNwXBCHTVCk9606	rigid:aNozi6GlDkVv3kZ8Bvj+78oweoQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z3G7	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466215	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z3g7_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466275	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:JvPbgQ8n9O7hA1kBCmeExmxyX149606	rigid:sJP/1W3h+/JRFhkCLG4pZgpixxY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z368	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466240	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z368_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466291	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:QqkkEDwGhMlbxJz7AWZzkw7EAeo9606	rigid:eb0f9JZuRlj3xh0JdqES8YczcH0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q86VP1	uniprotkb:A0A0S2Z604	intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612	intact:EBI-16430119	psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name)	psi-mi:a0a0s2z604_human(display_long)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466307	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|dip:DIP-33010N|ensembl:ENSG00000106052(gene)|ensembl:ENST00000396319(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0019900"(kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|reactome:R-HSA-5357905|reactome:R-HSA-936440|entrezgene/locuslink:8887(identity)	go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017119"(Golgi transport complex)|interpro:IPR019335|entrezgene/locuslink:91949(identity)	intact:EBI-16430385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606	rogid:tyBD/wDJzjaIBQVhEFlQTm1Ptec9606	rigid:rHtfEUJEohyewBXuvAuQZJgKwT8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UP83-3	uniprotkb:P83436	intact:EBI-16431689	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:q9up83-3(display_long)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466323	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-389502(isoform-parent)|entrezgene/locuslink:10466(identity)	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|entrezgene/locuslink:91949(identity)	intact:EBI-16431696(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: COG7_1 expression is provided in figureS2C."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8d6Z5Ozyy5EOhcfo2J/n6PKdF409606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:ZefIs3myeOmkHS4UlcNP1U6MkUI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6C2-2	uniprotkb:P83436	intact:EBI-11748557	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:q9y6c2-2(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466339	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-744586(isoform-parent)|uniprotkb:Q9Y6C2-2(isoform-parent)|entrezgene/locuslink:11117(identity)	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|entrezgene/locuslink:91949(identity)	intact:EBI-16440082(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: COG7_1 expression is provided in figureS2C."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NGDxonJvrK0A9caBPSPej/CS+q89606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:2FiFGR7SstOSLM4pmLXFQXubNco	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6PIL6	uniprotkb:A0A0S2Z3K0	intact:EBI-1051469|uniprotkb:Q4W5G8|uniprotkb:Q8NEU0|uniprotkb:Q9BWT2|uniprotkb:Q9H294|uniprotkb:Q9H2A4|uniprotkb:Q3YAB9|uniprotkb:Q3YAC0|uniprotkb:Q3YAB8|uniprotkb:Q3YAC1|uniprotkb:Q3YAC2|ensembl:ENSP00000371587	intact:EBI-16431143	psi-mi:kcip4_human(display_long)|uniprotkb:A-type potassium channel modulatory protein 4(gene name synonym)|uniprotkb:Potassium channel-interacting protein 4(gene name synonym)|uniprotkb:Calsenilin-like protein(gene name synonym)|uniprotkb:KCNIP4(gene name)|psi-mi:KCNIP4(display_short)|uniprotkb:CALP(gene name synonym)|uniprotkb:KCHIP4(gene name synonym)	psi-mi:a0a0s2z3k0_human(display_long)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466355	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001030176.1|refseq:NP_079497.2|refseq:NP_671710.1|refseq:NP_671711.1|refseq:NP_671712.1|refseq:NP_001030175.1|refseq:XP_016864142.1|ensembl:ENSG00000185774(gene)|ensembl:ENST00000382152(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|reactome:R-HSA-5576894|entrezgene/locuslink:80333(identity)	go:"GO:0005581"(collagen trimer)|interpro:IPR008160(Collagen triple helix repeat)|entrezgene/locuslink:1278(identity)	intact:EBI-16429045(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ihBpvroA94ZQzV1E9Y79lF8xmqc9606	rogid:UpD+NxJv+KzbpC6BW3iMpACMxCk9606	rigid:buponVSb5wkL6KU7M6q8lrgSyrg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:Q9BT78	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466371	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N|entrezgene/locuslink:51138(identity)	intact:EBI-16432802(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_1 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606	rigid:gp4ZN8AgYJUbI9P1dU8sCsbJIyk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P08727	intact:EBI-16432800	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	-	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"ccsb isoform id: cops4_2"(display_short)|psi-mi:EBI-16432800(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466387	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	entrezgene/locuslink:51138(identity)	intact:EBI-16435370(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_2 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:vPY3rKRE6kWXbUK0bKK5SHSR+409606	rigid:jtm1QzO9sbkRG7UJfsr+SFXT/V4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	intact:EBI-16432800	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	-	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"ccsb isoform id: cops4_2"(display_short)|psi-mi:EBI-16432800(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466403	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	entrezgene/locuslink:51138(identity)	intact:EBI-16439799(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_2 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:vPY3rKRE6kWXbUK0bKK5SHSR+409606	rigid:3fBg86Cj6SDpnsGSMo74R8yL5W8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND30	uniprotkb:P46108	intact:EBI-744056|uniprotkb:O75337|uniprotkb:Q8WW26|intact:EBI-28975311|uniprotkb:B7Z433|uniprotkb:E9PK77|ensembl:ENSP00000299492	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:lipb2_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2(gene name synonym)|uniprotkb:PPFIBP2(gene name)|psi-mi:PPFIBP2(display_short)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466419	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003612.2|ensembl:ENSP00000299492|ensembl:ENST00000528883|ensembl:ENSP00000435469|ensembl:ENST00000530181|ensembl:ENSP00000437321|refseq:NP_001243497.1|refseq:XP_016873932.1|dip:DIP-42373N|ensembl:ENSG00000166387(gene)|ensembl:ENST00000299492(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030435|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q8ND30|rcsb pdb:3QH9|reactome:R-HSA-388844|entrezgene/locuslink:8495(identity)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422|entrezgene/locuslink:1398(identity)	intact:EBI-16431778(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:36bMLWHJuGN5eItyc1HvhoLonZA9606	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	rigid:TVu3IYjzNPduuCgZ4M09VNAei9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P41970	uniprotkb:P46108	intact:EBI-1758534|uniprotkb:Q6FG57|uniprotkb:Q6GU29|uniprotkb:Q9UD17|uniprotkb:B2R6S6|ensembl:ENSP00000228741	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:elk3_human(display_long)|uniprotkb:ELK3(gene name)|psi-mi:ELK3(display_short)|uniprotkb:NET(gene name synonym)|uniprotkb:SAP2(gene name synonym)|uniprotkb:ETS-related protein NET(gene name synonym)|uniprotkb:ETS-related protein ERP(gene name synonym)|uniprotkb:Serum response factor accessory protein 2(gene name synonym)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466435	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005221.2|refseq:XP_006719338.1|ensembl:ENSG00000111145(gene)|ensembl:ENST00000228741(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0042060"(wound healing)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:2004(identity)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422|entrezgene/locuslink:1398(identity)	intact:EBI-16437677(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:iPkf41e5YQWRa3P5QiEz/npvNgM9606	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	rigid:5RSOtc25JPI6hFuIsiWZKbOMW5M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N205-2	intact:EBI-16466451	intact:EBI-12099160|ensembl:ENSP00000343152	-	psi-mi:q8n205-2(display_long)|uniprotkb:SYNE4(gene name)|psi-mi:SYNE4(display_short)|uniprotkb:C19orf46(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 4(gene name synonym)|uniprotkb:KASH domain-containing protein 4(gene name synonym)	psi-mi:"ccsb isoform id: csgalnact2_3"(display_short)|psi-mi:EBI-16466451(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466454	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181392(gene)|ensembl:ENST00000340477(transcript)|intact:EBI-7131783(isoform-parent)|uniprotkb:Q8N205-2(isoform-parent)|entrezgene/locuslink:163183(identity)	entrezgene/locuslink:55454(identity)	intact:EBI-16434758(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:wZZnrCoICL0cSTPDAK5tBR6uoAk9606	rogid:mpixmCTfLzsS2yiPVxjCibJKsm49606	rigid:nO/VzYfiAqvnynKwjVEV4mqF5H8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P49682	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466470	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N|entrezgene/locuslink:2833(identity)	intact:EBI-16432546(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:I7HJgWKXtRx54VBh8CdtdsrF+3U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NP66	uniprotkb:Q9UJW0	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	intact:EBI-2134033|uniprotkb:Q8TAN8|uniprotkb:D3DQH0|intact:EBI-2559420|uniprotkb:B3KWW0|uniprotkb:E5RGT5|ensembl:ENSP00000416968	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:dctn4_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)|uniprotkb:Dynactin subunit p62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466486	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	refseq:XP_011535946.1|refseq:XP_011535947.1|refseq:NP_001129116.1|refseq:NP_057305.1|refseq:NP_001129115.1|ensembl:ENSG00000132912(gene)|ensembl:ENST00000447998(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005869"(dynactin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0030017"(sarcomere)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008603(Dynactin p62)|mint:Q9UJW0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|entrezgene/locuslink:51164(identity)	intact:EBI-16432592(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:JradQZl06O4u9N3HH+cpvdP05RA9606	rigid:7x1gb+ZU+yl4EAh4l2qfaD0WCGY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NP66	uniprotkb:A0A0S2Z5B8	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	intact:EBI-16466502	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z5b8_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466509	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	go:"GO:0005869"(dynactin complex)|interpro:IPR008603(Dynactin p62)|entrezgene/locuslink:51164(identity)	intact:EBI-16432592(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:YbENGRFyl7aDyzeVH/us/i2mScQ9606	rigid:FuE4sN6NCBNquN9rycqCGPkrRxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5D5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16432590	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5d5_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466544	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:51164(identity)	intact:EBI-16438444(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:c2CExeSJVtEGU1+sUEgWSSI9ZVc9606	rigid:8u1xxfKbuhbcco/xawYSDjLxrLY	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5B8	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16466502	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5b8_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466525	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0005869"(dynactin complex)|interpro:IPR008603(Dynactin p62)|entrezgene/locuslink:51164(identity)	intact:EBI-16438444(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:YbENGRFyl7aDyzeVH/us/i2mScQ9606	rigid:lw5Jf/tco3aHGm5BOEvdaasSHvQ	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00471	uniprotkb:Q8WXU2-2	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466713	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1|entrezgene/locuslink:10640(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16430219(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:/L3X/1o/laqq0ILl5IqndU7Dpx0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UPQ8	uniprotkb:Q9UMX0-2	intact:EBI-8645574|ensembl:ENSP00000361667|uniprotkb:Q5SRE6|intact:MINT-4724096|intact:MINT-8163513	intact:EBI-10173939|ensembl:ENSP00000257468	psi-mi:dolk_human(display_long)|uniprotkb:KIAA1094(gene name synonym)|uniprotkb:UNQ2422/PRO4980(orf name)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)|uniprotkb:TMEM15(gene name synonym)|uniprotkb:Transmembrane protein 15(gene name synonym)	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466662	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175283(gene)|ensembl:ENST00000372586(transcript)|go:"GO:0004168"(dolichol kinase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043048"(dolichyl monophosphate biosynthetic process)|interpro:IPR026566|interpro:IPR032974|reactome:R-HSA-446199|reactome:R-HSA-4755583|refseq:NP_055723.1|entrezgene/locuslink:22845(identity)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	intact:EBI-16431167(see-also)	function:"Defects in TMEM15 are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy"	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:oVMRd2DWTKCgO7cySF3k2IbBfn09606	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rigid:Q4a0WtyOeUoewKJV4Poln8Y6ELo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P22001	uniprotkb:A0A0S2Z5Y1	intact:EBI-8627664|ensembl:ENSP00000358784|intact:MINT-1528422|uniprotkb:Q5VWN2	intact:EBI-16431159	psi-mi:kcna3_human(display_long)|uniprotkb:KCNA3(gene name)|psi-mi:KCNA3(display_short)|uniprotkb:HGK5(gene name synonym)|uniprotkb:HPCN3(gene name synonym)|uniprotkb:HLK3(gene name synonym)|uniprotkb:"Voltage-gated K(+) channel HuKIII"(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv1.3(gene name synonym)	psi-mi:a0a0s2z5y1_human(display_long)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466694	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004050(Potassium channel, voltage dependent, Kv1.3)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:4BGC|rcsb pdb:7EJ1|rcsb pdb:7EJ2|reactome:R-HSA-1296072|go:"GO:0099056"(integral component of presynaptic membrane)|ensembl:ENST00000369769(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|ensembl:ENSG00000177272(gene)|refseq:NP_002223.3|dip:DIP-44822N|entrezgene/locuslink:3738(identity)	go:"GO:0016301"(kinase activity)|interpro:IPR032974|entrezgene/locuslink:22845(identity)	intact:EBI-16432872(see-also)	comment:mint|function:Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QH0tUFo3Db+XWLTawQfDhma+3jg9606	rogid:/tQYfLrD7OKrWUFrog22eoJZWhA9606	rigid:bEFS9bMvKsyzh27AZCo0Odr8o70	true	sufficient binding region:53-575	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q16854	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-3908194|uniprotkb:P78532|uniprotkb:Q16759|uniprotkb:Q4ZG09|uniprotkb:Q96BC1|uniprotkb:Q7L1W9|intact:EBI-16466603|ensembl:ENSP00000264093	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:dguok_human(display_long)|uniprotkb:DGUOK(gene name)|psi-mi:DGUOK(display_short)|uniprotkb:DGK(gene name synonym)|uniprotkb:Deoxyadenosine kinase, mitochondrial(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466606	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_550438.1|refseq:NP_550440.1|refseq:NP_001305788.1|refseq:NP_001305789.1|refseq:NP_001305790.1|refseq:NP_001305791.1|refseq:NP_001305792.1|ensembl:ENSG00000114956(gene)|ensembl:ENST00000264093(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008617"(guanosine metabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046070"(dGTP metabolic process)|go:"GO:0046122"(purine deoxyribonucleoside metabolic process)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|rcsb pdb:2OCP|reactome:R-HSA-74217|entrezgene/locuslink:1716(identity)	intact:EBI-16436769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:WTctzYSxFE3aQ1L7s9fNMkw8nII9606	rigid:k3zOQaqmy0R6gUTqoer73JMX4mY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q9NR28-3	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16466622|ensembl:ENSP00000320343	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:q9nr28-3(display_long)|uniprotkb:Direct IAP-binding protein with low pI(gene name synonym)|uniprotkb:Second mitochondria-derived activator of caspase(gene name synonym)|uniprotkb:SMAC3(isoform synonym)|uniprotkb:DIABLO(gene name)|psi-mi:DIABLO(display_short)|uniprotkb:SMAC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466646	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	intact:EBI-517508(isoform-parent)|ensembl:ENST00000353548(transcript)|ensembl:ENSG00000184047(gene)|entrezgene/locuslink:56616(identity)	intact:EBI-16439070(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:MofZ1Z5vpCxl/pplvbGJlHn9oqQ9606	rigid:QdU3tL6Iyt/N7bEgCfKgh7Jardk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:Q9NR28-3	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-16466622|ensembl:ENSP00000320343	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:q9nr28-3(display_long)|uniprotkb:Direct IAP-binding protein with low pI(gene name synonym)|uniprotkb:Second mitochondria-derived activator of caspase(gene name synonym)|uniprotkb:SMAC3(isoform synonym)|uniprotkb:DIABLO(gene name)|psi-mi:DIABLO(display_short)|uniprotkb:SMAC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466630	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	intact:EBI-517508(isoform-parent)|ensembl:ENST00000353548(transcript)|ensembl:ENSG00000184047(gene)|entrezgene/locuslink:56616(identity)	intact:EBI-16432884(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:MofZ1Z5vpCxl/pplvbGJlHn9oqQ9606	rigid:dANcD71avPgXLRaiAk7eR7+oomQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q16854	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-3908194|uniprotkb:P78532|uniprotkb:Q16759|uniprotkb:Q4ZG09|uniprotkb:Q96BC1|uniprotkb:Q7L1W9|intact:EBI-16466603|ensembl:ENSP00000264093	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:dguok_human(display_long)|uniprotkb:DGUOK(gene name)|psi-mi:DGUOK(display_short)|uniprotkb:DGK(gene name synonym)|uniprotkb:Deoxyadenosine kinase, mitochondrial(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466587	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_550438.1|refseq:NP_550440.1|refseq:NP_001305788.1|refseq:NP_001305789.1|refseq:NP_001305790.1|refseq:NP_001305791.1|refseq:NP_001305792.1|ensembl:ENSG00000114956(gene)|ensembl:ENST00000264093(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008617"(guanosine metabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046070"(dGTP metabolic process)|go:"GO:0046122"(purine deoxyribonucleoside metabolic process)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|rcsb pdb:2OCP|reactome:R-HSA-74217|entrezgene/locuslink:1716(identity)	intact:EBI-16436769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:WTctzYSxFE3aQ1L7s9fNMkw8nII9606	rigid:k3zOQaqmy0R6gUTqoer73JMX4mY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UPQ8	uniprotkb:Q9UMX0	intact:EBI-8645574|ensembl:ENSP00000361667|uniprotkb:Q5SRE6|intact:MINT-4724096|intact:MINT-8163513	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:dolk_human(display_long)|uniprotkb:KIAA1094(gene name synonym)|uniprotkb:UNQ2422/PRO4980(orf name)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)|uniprotkb:TMEM15(gene name synonym)|uniprotkb:Transmembrane protein 15(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466678	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175283(gene)|ensembl:ENST00000372586(transcript)|go:"GO:0004168"(dolichol kinase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043048"(dolichyl monophosphate biosynthetic process)|interpro:IPR026566|interpro:IPR032974|reactome:R-HSA-446199|reactome:R-HSA-4755583|refseq:NP_055723.1|entrezgene/locuslink:22845(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	intact:EBI-16432812(see-also)	function:"Defects in TMEM15 are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:oVMRd2DWTKCgO7cySF3k2IbBfn09606	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rigid:sKr41ALojKLKhYejm2Sgr3FdRKo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF50	uniprotkb:Q9BSJ6	intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467251	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1|entrezgene/locuslink:81704(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439048(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:i9naM6SDUcWAcsgH2HRhBa8mlTI	true	sufficient binding region:1587-2099	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:Q9BSJ6	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467235	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16437235(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:pyMAWN8gcMG8BvHX07CAvpnaajg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:Q9BSJ6	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467219	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16437215(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:wfUpZAUpq7k1LmdHp7BlpVVb3Nc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:Q9BSJ6	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467203	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16436002(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:9PAr5YI/fFfX/lsYbrfx9Ac3lSI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:Q9BSJ6	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467187	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16435214(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:o1uK/PjbIh/Aj0MNS94tr4m6VF0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:Q9BSJ6	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467171	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16434150(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:hqeECR9+Yf/hoSnqtfk93gTEkdQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q9BSJ6	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467155	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16432218(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:/fegmfVLdC/MrbExQTRzffBtGYs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9BSJ6	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467139	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16432128(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:sFiTwQCqGFywSi62MN6Su2krW9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q9BSJ6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467120	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16431852(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:H2JbglrA/LBRiTLx1TPAPMZGtak	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:Q9BSJ6	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467104	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16431615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:OWLuKZexqiy3AxvQ+gndUjTF23I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:Q9BSJ6	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467088	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16430867(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:VEYrkRwqIMqNyQ4Gvp4/GHDFjns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9BSJ6	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467072	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16429917(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:sFiTwQCqGFywSi62MN6Su2krW9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:Q9BSJ6	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467056	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16428890(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:oVdy0z/sL8nQY4wVN7pC7eagTxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43365	intact:EBI-16467021	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	-	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"ccsb isoform id: fam54b_2"(display_short)|psi-mi:EBI-16467021(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467040	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	entrezgene/locuslink:56181(identity)	intact:EBI-16440312(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:s6tB/T5PNwpafrH/RLNC5RLnCn89606	rigid:Mg/HXliSSKCiVCZFso95L3Evuv0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVT9	intact:EBI-16467021	intact:EBI-3506974|uniprotkb:Q9H018|uniprotkb:Q9H820|uniprotkb:B4E2W7|ensembl:ENSP00000276569	-	psi-mi:armc1_human(display_long)|uniprotkb:ARMC1(gene name)|psi-mi:ARMC1(display_short)|uniprotkb:ARCP(gene name synonym)	psi-mi:"ccsb isoform id: fam54b_2"(display_short)|psi-mi:EBI-16467021(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467024	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060590.1|ensembl:ENSG00000104442(gene)|ensembl:ENST00000276569(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016617(Uncharacterised conserved protein UCP013899, metal binding)|interpro:IPR036163|mint:Q9NVT9|refseq:NP_001273631.1|refseq:XP_016869094.1|entrezgene/locuslink:55156(identity)	entrezgene/locuslink:56181(identity)	intact:EBI-16437325(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WP/jzUyBwj/g9TLQ38jY56DYpRI9606	rogid:s6tB/T5PNwpafrH/RLNC5RLnCn89606	rigid:v0q1K18Q39HeDBm3fFkWnuTYI6Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z6M9	intact:EBI-16439278	intact:EBI-16428876	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z6m9_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467005	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR018619|refseq:XP_005249952.1|entrezgene/locuslink:84668(identity)	intact:EBI-16439442(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:BB9OGAPlTXTKfaNW+w3TSxbbHow9606	rigid:jhHPDW+Yjb8M1tzdjfPBmKP9TZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9BYI3	intact:EBI-16439278	intact:EBI-11065686|uniprotkb:A0A024RA06|uniprotkb:A4D145|uniprotkb:B8ZZJ1|uniprotkb:Q6N010|uniprotkb:Q75MR4|uniprotkb:Q7LDZ4|uniprotkb:Q96MX1|uniprotkb:Q96NQ6|ensembl:ENSP00000403396|intact:EBI-16428864	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:hycci_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)|uniprotkb:DRCTNNB1A(gene name synonym)|uniprotkb:Down-regulated by CTNNB1 protein A(gene name synonym)|uniprotkb:Protein FAM126A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466989	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_115970.2|refseq:XP_011513891.1|refseq:XP_005249951.1|ensembl:ENSG00000122591(gene)|ensembl:ENST00000432176(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0042552"(myelination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619|rcsb pdb:5DSE|rcsb pdb:6BQ1|entrezgene/locuslink:84668(identity)	intact:EBI-16439442(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:dQX246o/4bB9UkgG+9Be4mIOfxU9606	rigid:0G52UlOtjbg0zUgTgLNO45HrLg0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z6M9	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16428876	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z6m9_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466973	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR018619|refseq:XP_005249952.1|entrezgene/locuslink:84668(identity)	intact:EBI-16435564(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:BB9OGAPlTXTKfaNW+w3TSxbbHow9606	rigid:7c68waStcr0Oe7MWzEiDNd0slwg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13557-8	uniprotkb:Q13216-2	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	intact:EBI-16466949|ensembl:ENSP00000494466|ensembl:ENSP00000502154	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:q13216-2(display_long)|uniprotkb:ERCC8(gene name)|psi-mi:ERCC8(display_short)|uniprotkb:CKN1(gene name synonym)|uniprotkb:CSA(gene name synonym)|uniprotkb:Cockayne syndrome WD repeat protein CSA(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466957	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	intact:EBI-295260(isoform-parent)|uniprotkb:Q13216-2(isoform-parent)|ensembl:ENSG00000049167(gene)|ensembl:ENST00000647486(transcript)|ensembl:ENST00000675229(transcript)|entrezgene/locuslink:1161(identity)	intact:EBI-16440912(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	rogid:Lf4ue+p6QP9+CoKq1z0j6IbDzk89606	rigid:pNv+PvviwHCd/+Zooh0/L5ioDTc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:Q8IYU8	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-3197790|ensembl:ENSP00000371811|uniprotkb:Q8N0T6|uniprotkb:Q8NAX8	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:micu2_human(display_long)|uniprotkb:MICU2(gene name)|psi-mi:MICU2(display_short)|uniprotkb:EF-hand domain-containing family member A1(gene name synonym)|uniprotkb:EFHA1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466933	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	ensembl:ENSG00000165487(gene)|ensembl:ENST00000382374(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:1990246"(uniplex complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR039800|rcsb pdb:6AGH|rcsb pdb:6IIH|rcsb pdb:6K7Y|rcsb pdb:6LB7|rcsb pdb:6LB8|rcsb pdb:6LE5|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|rcsb pdb:6XQN|rcsb pdb:6XQO|reactome:R-HSA-8949215|reactome:R-HSA-8949664|refseq:NP_689939.1|entrezgene/locuslink:221154(identity)	intact:EBI-16439974(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:qj7nAE+DvoW/RWlr4VWGSbhS6Mc9606	rigid:ksLVZyn2bja1KF48zbJW1U9k2o8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14188-5	uniprotkb:Q2Z196	intact:EBI-12181237|ensembl:ENSP00000418590|ensembl:ENSP00000420599	intact:EBI-16466898|ensembl:ENSP00000389113	psi-mi:q14188-5(display_long)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym)|uniprotkb:E2F dimerization partner 2(gene name synonym)	psi-mi:q2z196_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466917	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-752268(isoform-parent)|uniprotkb:Q14188-5(isoform-parent)|ensembl:ENSG00000114126(gene)|ensembl:ENST00000467072(transcript)|ensembl:ENST00000486111(transcript)|entrezgene/locuslink:7029(identity)	ensembl:ENSG00000169016(gene)|ensembl:ENST00000421117(transcript)|entrezgene/locuslink:1876(identity)	intact:EBI-16439164(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:rdh6QA6IAPo+ksMkB9o5Kn+kKfw9606	rogid:MuHBDwxpZFl1AqkQHVebZ9XMNyc9606	rigid:ktoe5y+VJmI5vUZQvMtOqEOF09s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14186	uniprotkb:Q2Z196	intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519	intact:EBI-16466898|ensembl:ENSP00000389113	psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym)	psi-mi:q2z196_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466901	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|entrezgene/locuslink:7027(identity)	ensembl:ENSG00000169016(gene)|ensembl:ENST00000421117(transcript)|entrezgene/locuslink:1876(identity)	intact:EBI-16438111(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606	rogid:MuHBDwxpZFl1AqkQHVebZ9XMNyc9606	rigid:ZxA4JyRAfkrq/m/0W99OHp1kMYU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EA4	uniprotkb:A0A0S2Z5X9	intact:EBI-715381|uniprotkb:Q8TEC8|uniprotkb:Q9HD44|uniprotkb:Q9NX97|uniprotkb:C9JS47|ensembl:ENSP00000265295|uniprotkb:B4E393	intact:EBI-16466729	psi-mi:spdly_human(display_long)|uniprotkb:SPDL1(gene name)|psi-mi:SPDL1(display_short)|uniprotkb:Arsenite-related gene 1 protein(gene name synonym)|uniprotkb:CCDC99(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 99(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.4A(gene name synonym)|uniprotkb:Spindle apparatus coiled-coil domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466881	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060255.3|ensembl:ENSG00000040275(gene)|ensembl:ENST00000265295(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|interpro:IPR028593|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001316570.1|dip:DIP-47296N|entrezgene/locuslink:54908(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16437624(see-also)|intact:EBI-16437634(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CzXKB2VOL2ZBmQjyc4vGxQ0cTnY9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:X13wQgydSj0ihGCODPcFtZvBg9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:A0A0S2Z5X9	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-16466729	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466865	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16435900(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:mkbsRmqVDmpfjG7UGiH6tEOrU8Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:Q8WXU2-2	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466849	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16435900(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:MOOBusOlEKu1qfDAyOxYX83rDhU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UNE7	intact:EBI-16430217	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	-	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"ccsb isoform id: dyx1c1_3"(display_short)|psi-mi:EBI-16430217(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466833	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	entrezgene/locuslink:161582(identity)	intact:EBI-16435264(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:m0aEcT+ILE0RLI1nuExTVcJ+UO09606	rigid:Y7vI6BZYDvPL+DCb4s/cPbycINc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UNE7	uniprotkb:A0A0S2Z5X9	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	intact:EBI-16466729	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466817	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16435264(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:nxm4dB1aWljQHkH4QLAda5itvXk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N4Y2-3	uniprotkb:A0A0S2Z5X9	intact:EBI-11982645|ensembl:ENSP00000409256|ensembl:ENSP00000432334	intact:EBI-16466729	psi-mi:q8n4y2-3(display_long)|uniprotkb:CRACR2B(gene name)|psi-mi:CRACR2B(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2B(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2B(gene name synonym)|uniprotkb:EFCAB4A(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466801	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8N4Y2-3(isoform-parent)|intact:EBI-10267893(isoform-parent)|ensembl:ENSG00000177685(gene)|ensembl:ENST00000528542(transcript)|ensembl:ENST00000450448(transcript)|entrezgene/locuslink:283229(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16431201(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:76w0B5349e/QlU4aMfv4UAGek8I9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:YM5cviATKyPQ/l7HmKlYfbic9FM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N4Y2-3	uniprotkb:Q8WXU2-2	intact:EBI-11982645|ensembl:ENSP00000409256|ensembl:ENSP00000432334	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:q8n4y2-3(display_long)|uniprotkb:CRACR2B(gene name)|psi-mi:CRACR2B(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2B(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2B(gene name synonym)|uniprotkb:EFCAB4A(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466785	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8N4Y2-3(isoform-parent)|intact:EBI-10267893(isoform-parent)|ensembl:ENSG00000177685(gene)|ensembl:ENST00000528542(transcript)|ensembl:ENST00000450448(transcript)|entrezgene/locuslink:283229(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16431201(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:76w0B5349e/QlU4aMfv4UAGek8I9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:3xkwFesfv7Klef+eJKTwerSQ4hI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:A0A0S2Z5X9	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-16466729	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466769	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16430761(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:s15I2OfpNaW9fEoq6Gy5yhLnXvg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q8WXU2-2	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466753	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16430761(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:gpAgk7W+1I1/WKapQoyOgrTBmlU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00471	uniprotkb:A0A0S2Z5X9	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	intact:EBI-16466729	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466737	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1|entrezgene/locuslink:10640(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16430219(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:L3uoaWobFnPAhT8VaRjD9rj+60Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q9BSJ6	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467286	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439994(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:AmJaI7kgWRgy9LQxEivk42xb6D8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q9BSJ6	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467270	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439080(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:HaL/t9TltJZzvmbvScc+5r7n8qo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:A0A0S2Z3S1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-16439494	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467321	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16433881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:d2VOJY77uH0qNeQW1wmIHZwKqgA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:A0A0S2Z3W0	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-16467337	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467340	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16433881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:GVDtFl6K+6dXXDgaa3MvUwGU8Q8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z3S1	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16439494	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467356	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16438051(see-also)|intact:EBI-16438061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:sxDBZCrF3FDKBOm77xgOYhVvAJM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z3W0	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16467337	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467373	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16438051(see-also)|intact:EBI-16438061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:ASs+B/85HSdSkw7dgRt5I8l2tI4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z3S1	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16439494	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467390	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16439809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:udqlk9foab/G3FXs98eGQSjfoJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z3W0	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16467337	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467406	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16439809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:Lriz4YAhPWNVlJipgQsP8YDPb2k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:Q9NRD0	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-11615366|uniprotkb:B2RB40|uniprotkb:D3DP41|uniprotkb:G5E9Z0|uniprotkb:Q6UWN4|uniprotkb:Q8IWE1|uniprotkb:Q9NRP5|uniprotkb:Q9UKC4|ensembl:ENSP00000377280	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:fbx8_human(display_long)|uniprotkb:FBXO8(gene name)|psi-mi:FBXO8(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBX8(gene name synonym)|uniprotkb:DC10(orf name)|uniprotkb:UNQ1877/PRO4320(orf name)|uniprotkb:F-box/SEC7 protein FBS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467422	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	refseq:NP_036312.2|ensembl:ENSG00000164117(gene)|ensembl:ENST00000393674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR023394|interpro:IPR035999|interpro:IPR036047|entrezgene/locuslink:26269(identity)	intact:EBI-16434724(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:iw1wQu/WnQC2vnge/KH840EAPr89606	rigid:lbiO5UVLUdwL3MTUOM8DxO5IYCw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:Q9BSJ6	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467302	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16440764(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:veDnZvJLUXdys9unRCLGl4QZc2A	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:O14964	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467834	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	intact:EBI-16431864(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rigid:9rOFVAZ6zJQVQJ3FnYuf7dHFnuQ	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q8WW76	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16467458	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:q8ww76_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467470	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0051258"(protein polymerization)|go:"GO:0030168"(platelet activation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439092(see-also)|intact:EBI-16439104(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:KyNpb3Z1gdvzVwZ5muhihBKkF249606	rigid:tRSNnZlta/WnIl+7vG2U6Rcnb5Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:A0A0S2Z3E8	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16439506	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:a0a0s2z3e8_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467487	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0030168"(platelet activation)|go:"GO:0051258"(protein polymerization)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439092(see-also)|intact:EBI-16439104(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:SYq0A8PukG7MmEnVdnJftwnVatk9606	rigid:7amqe5BJlpz21IIHbBcf84MkwbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8WW76	intact:EBI-16439278	intact:EBI-16467458	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:q8ww76_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467504	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0051258"(protein polymerization)|go:"GO:0030168"(platelet activation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439517(see-also)|intact:EBI-16439527(see-also)|intact:EBI-16439537(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:KyNpb3Z1gdvzVwZ5muhihBKkF249606	rigid:iHPGYBhNr/M8cpcqGe5kGV1RIKA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P07954	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467522	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N|entrezgene/locuslink:2271(identity)	intact:EBI-16428911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	rigid:bbpYItEBprS5Gc3uLow0s9CPNXg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:A0A0S2Z4H0	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-16467538	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:a0a0s2z4h0_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467552	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR024083|interpro:IPR018951|interpro:IPR022761|interpro:IPR008948(L-Aspartase-like)|entrezgene/locuslink:2271(identity)	intact:EBI-16428911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:ILOCbSyaw1/FI9WqVHCYNaKIB6o9606	rigid:d5Xy2RDBdtkkdwxkRf61SOX8d9A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q99259	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467568	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16430773(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:6yqsQ8P7ioS1J5/wXfT8brutlfo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	intact:EBI-16467584	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	-	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467587	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16430773(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:cyNJsKXk1cCm2d7/hPh83QHFXrU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:Q99259	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467603	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16434433(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:99wCOpsohF+jq4jLhPfVr08LoqI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	intact:EBI-16467584	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	-	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467619	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16434433(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:hVidg71t0Q6qfqDEBP7oNt3r2jc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	intact:EBI-16467584	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	-	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467635	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16436031(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:Rf3FBuXC3qc6TlA7io6rQ9ycVqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:Q99259	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467651	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16436605(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:IBLUcybnTRx7sP3L7MDdB5238as	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	intact:EBI-16467584	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	-	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467667	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16436605(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:2Oao7SqotMIMaVpKfs0gAU7+oSc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	intact:EBI-16467584	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	-	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467683	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16437245(see-also)|intact:EBI-16437255(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:W+D2Ix09eBLMHyidvMSomz9DasM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	intact:EBI-16467584	intact:EBI-11522760|ensembl:ENSP00000365816	-	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467700	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16439114(see-also)|intact:EBI-16439124(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:bx7WKUrui4ezD7LUl33iICFldWU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	intact:EBI-16467584	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	-	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467717	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16440004(see-also)|intact:EBI-16440014(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:mmJgBRmD8pdsbpHSBLpzc/+oA9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR7	uniprotkb:Q99259	intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467734	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|entrezgene/locuslink:83897(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16440206(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:Aa7DC819tqvKCHa/IP8v5fp2gL0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR7	intact:EBI-16467584	intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215	-	psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467750	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|entrezgene/locuslink:83897(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16440206(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:O2V/Q2pdzf2/oioWEp78lcnPGWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9BRX5	intact:EBI-16439278	intact:EBI-2857315|uniprotkb:B2RDP3|uniprotkb:Q9H870|uniprotkb:E9PB21|ensembl:ENSP00000318196	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:psf3_human(display_long)|uniprotkb:GINS3(gene name)|psi-mi:GINS3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:GINS complex subunit 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467766	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001119601.1|refseq:NP_001119602.1|refseq:NP_073607.2|dip:DIP-29333N|ensembl:ENSG00000181938(gene)|ensembl:ENST00000318129(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|mint:Q9BRX5|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974|entrezgene/locuslink:64785(identity)	intact:EBI-16439547(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:3anXwRLIwu/t1G1v+P1yzhh7QqA9606	rigid:2gdXs5udza36qzmAJeEm2Eys5Xk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P49407	uniprotkb:A0A0S2Z5F2	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581	intact:EBI-16440982	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	psi-mi:a0a0s2z5f2_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467782	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N|entrezgene/locuslink:408(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:NP_001305794.1|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16434180(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_3 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	rogid:fJAMGRDcSZgsh1BDT1O6WFgX1mc9606	rigid:2sSYsEZmwNO2BNdo9alDQe6W8K8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P49407	uniprotkb:A0A0S2Z594	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581	intact:EBI-16467798	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	psi-mi:a0a0s2z594_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467801	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N|entrezgene/locuslink:408(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16434180(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_4 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	rogid:ZSlpNMZa5lzAcw3yv60jmgcjt3Y9606	rigid:2WNPXbVX5T+HAHqOJux1Jv3PGkc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14749	uniprotkb:A0A0S2Z594	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	intact:EBI-16467798	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:a0a0s2z594_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467817	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16440972(see-also)|intact:EBI-16440990(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_4 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	rogid:ZSlpNMZa5lzAcw3yv60jmgcjt3Y9606	rigid:JYTJqL24YSNOjE9kRFD3CkdMOxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z4Q4	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16429135	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467853	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433353(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:8k3uD5Pywqm2uWZisXqdSyH3Uss	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:O14964	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467869	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N|entrezgene/locuslink:10616(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	intact:EBI-16433452(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rigid:Z0mzCZAg9K8CUJJB74SEBYnhugY	true	sufficient binding region:11-510	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:Q8WVV9	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468261	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430618(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:kGjltN2MVv03cF1uqLykBg3V5Aw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05519-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11975029|ensembl:ENSP00000359989	intact:EBI-16468000	psi-mi:q05519-2(display_long)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468181	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q05519-2(isoform-parent)|intact:EBI-1051785(isoform-parent)|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370951(transcript)|entrezgene/locuslink:9295(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430291(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:jNkAVUlnfT59fvbzTBQJUfR7lxY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:4AiLxzgWVls10+YcOD1fg0n9uFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468245	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430482(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:taV4yOTGqu/l3SW3S1dG/UyjoJg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468229	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430482(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:Y5FiPLiIWcjo4UtXHLf/Fscbcqk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:A0A0S2Z5U3	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-16468000	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468213	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430321(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:AMMpyTpv9rdO35EP/DHt2T5v50A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:Q8WVV9	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468197	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430321(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:9JNd1rehkJDXrrhJ17mDDGcKbMM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468309	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430630(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:jAmvjM4nVl1VmNGE/PwQxF+MT3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468293	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430630(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:puQ79Hiivev1ih6wdghxHul/fNE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478-2	uniprotkb:A0A0S2Z4Q4	intact:EBI-16433586|ensembl:ENSP00000487973	intact:EBI-16429135	psi-mi:o75478-2(display_long)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467888	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000277104(gene)|ensembl:ENST00000633584(transcript)|intact:EBI-742268(isoform-parent)|uniprotkb:O75478-2(isoform-parent)|entrezgene/locuslink:6871(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433593(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JHWBurvcalqBr39eeJPqONrU9GM9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:uFKRuFxYi01Y3VOA7YXm8lp+n3g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:A0A0S2Z4Q4	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16429135	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467904	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433603(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:WHrWwh7FiczVvwI6zrwt2IPvSUA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14525	uniprotkb:A0A0S2Z4Q4	intact:EBI-1049638|uniprotkb:O76010|ensembl:ENSP00000251646|ensembl:ENSP00000459509	intact:EBI-16429135	psi-mi:kt33b_human(display_long)|uniprotkb:KRTHA3B(gene name synonym)|uniprotkb:Hair keratin, type I Ha3-II(gene name synonym)|uniprotkb:Keratin-33B(gene name synonym)|uniprotkb:KRT33B(gene name)|psi-mi:KRT33B(display_short)|uniprotkb:HHA3-II(gene name synonym)|uniprotkb:HKA3B(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467920	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002270.1|ensembl:ENSG00000131738(gene)|ensembl:ENSG00000263012(gene)|ensembl:ENST00000251646(transcript)|ensembl:ENST00000570596(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0042633"(hair cycle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q14525|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3884(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16437963(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:TDqltAJBdpwMGaQsl0Lznc8Y7Ns9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:iTmUFxCpN+QYKWQHSszaOTC29QM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HW7-2	uniprotkb:A0A0S2Z4Q4	intact:EBI-16438029|ensembl:ENSP00000433644	intact:EBI-16429135	psi-mi:q96hw7-2(display_long)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short)|uniprotkb:MSTP093(orf name)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467936	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5663129(isoform-parent)|ensembl:ENSG00000149262(gene)|ensembl:ENST00000529807(transcript)|entrezgene/locuslink:92105(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16438035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NDpAzVmN+obi0a3tSH56T4uc2UM9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:wQcqYNc2k+/uf/q4XzMBRgqh8r0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96MT8-3	uniprotkb:A0A0S2Z4Q4	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-16429135	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467952	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16438121(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:3vrh/6mkb2kr3zGZnXJUEFa8+ug	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z4Q4	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16429135	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467968	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16439819(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:iRxgkJfqsteoQL1YZwOGUSBtMXs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y577	uniprotkb:A0A0S2Z4Q4	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	intact:EBI-16429135	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467984	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:51127(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16440922(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:FN6B2ICEvGKQvUflEsOsIx+PV3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z5U3	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16468000	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468015	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16428940(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:C3+DAP61qWkmsKW7qdEia5E3PP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:Q8WVV9	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468031	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429161(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:yQrmAXR0+cabf1LbAvJ9XPbEuEA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z5U3	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16468000	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468047	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429161(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:mgHL3AZ8JlVKhDrFW4hFKutdwFU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:Q8WVV9	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468063	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429456(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:MBygL8ZauycaqUMbtiMqNNatzGg	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z5U3	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16468000	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468082	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429456(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:yZy0KIvqvkVjOwiijlWFnVPgnYM	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:Q8WVV9	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468101	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429642(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:r6fHbN0gYd+dtTJnxocgCeAez9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:A0A0S2Z5U3	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-16468000	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468117	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429642(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:o0PM1nakqNixz9cifbKHx9Tj/Zg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q8WVV9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468133	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429927(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:IF2wLf8qhyWMxYoj7vQplA0BgTI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z5U3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16468000	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468149	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429927(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:neNI/e6ct3YS3jVzT6XWIQyDcdA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05519-2	uniprotkb:Q8WVV9	intact:EBI-11975029|ensembl:ENSP00000359989	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q05519-2(display_long)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468165	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q05519-2(isoform-parent)|intact:EBI-1051785(isoform-parent)|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370951(transcript)|entrezgene/locuslink:9295(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430291(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:jNkAVUlnfT59fvbzTBQJUfR7lxY9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:BjXLWChezvd/7cAA1Pixi4rMixA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-16468000	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468277	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430618(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:dY/uU8Z314KZ5VUZ1icJ+TKFvyY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-16468000	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468905	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16437783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:/Bv7AVHjU5B2AaXT8/yW148GWZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q8WVV9	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468889	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16437783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:5ySNBJRGIAb8rGX7jYnr6qDFFvA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468873	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16437039(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:PQ+QADIonnpKZ0gCIaZndEbUpEk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468857	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16437039(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:vgNMG+uKo1MZ8xR04No929MiU5w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5U3	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16468000	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468841	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436987(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:KEjQcBgeCQrp2HhZ7aNl785Noy8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q8WVV9	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468825	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436987(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:4lmEAxuhH+R1cx+BJ4y3YRzHN90	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:A0A0S2Z5U3	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-16468000	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468809	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:09w7q405In8KRnkaYV68il1z010	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q8WVV9	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468793	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:1AlS2kOi8iFHCW/E2SJML65Vnl4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:A0A0S2Z5U3	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-16468000	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468777	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:HGdGLl/dTfIGqF+O82zHZx2o7hQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:Q8WVV9	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468761	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:VxPytE6UZRhjO0DKz44TlKx37og	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z5U3	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16468000	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468745	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Zz9b0BZXfncU87N4Z4kLLYiPNYI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:Q8WVV9	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468729	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:7/a/HrIlQeAI38isVUxefihNbVc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5U3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16468000	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468713	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435758(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Du5HIzuPqEj05euUqs/tA1pZIxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08117-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11741437|ensembl:ENSP00000221561	intact:EBI-16468000	psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468697	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435628(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:IJ6UpnDNCdRzcy9Yh1cP9h0BkpY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08117-2	uniprotkb:Q8WVV9	intact:EBI-11741437|ensembl:ENSP00000221561	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468681	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16435628(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:v24Xsp7Z75x5+AYMm7AMmWzc+GU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z5U3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16468000	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468665	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435122(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:DAMlqINnTPTpv6NKqJxS98MnPS8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q8WVV9	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468649	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16435122(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:FyI9KSjpY7b+U+M4xOLwYRbJ2xA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:A0A0S2Z5U3	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-16468000	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468632	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16434768(see-also)|intact:EBI-16434778(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:rzNpHAo4KZdPN17UNQJT9LJaXRs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13838	uniprotkb:A0A0S2Z5U3	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269	intact:EBI-16468000	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468616	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|entrezgene/locuslink:7919(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Eh7uekCpI3ddTEjTraIG2XjUq70	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13838	uniprotkb:Q8WVV9	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468600	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|entrezgene/locuslink:7919(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:CwITTwo/IdQaJ4Es/pPKgp0TPR4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P98175-4	uniprotkb:A0A0S2Z5U3	intact:EBI-10968858|ensembl:ENSP00000486115	intact:EBI-16468000	psi-mi:p98175-4(display_long)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468584	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-721525(isoform-parent)|ensembl:ENSG00000182872(gene)|ensembl:ENST00000628161(transcript)|entrezgene/locuslink:8241(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433799(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iKoFJ4bQhvGZ0Kq82Fhif11nCSA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:4s+ryo4+MB7DAB5XOj8PUuYq/S4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:A0A0S2Z5U3	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16468000	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468568	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433739(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:D1ta9nzNlWZpiXef7F3K4tx/sPI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q8WVV9	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468552	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433739(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:5wz5ShuFyIlTYmqnLli1FTU620E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00148	uniprotkb:A0A0S2Z5U3	intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1	intact:EBI-16468000	psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468536	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1|entrezgene/locuslink:10212(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433476(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:2+L52NBnsNKHr2x13xXMQG7FxTc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00148	uniprotkb:Q8WVV9	intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468520	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1|entrezgene/locuslink:10212(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433476(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:/Tnt2ZSOxCm3YzJ0zXDMNo3fwDg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z5U3	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16468000	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468504	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433047(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:G/gRHs9KISrMjyqBqzMt7Lgck9Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q8WVV9	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468488	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433047(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:WSVxO54hEznojoFpOz/bZpqWROg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:A0A0S2Z5U3	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-16468000	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468472	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:APmJJU6MaltQc/yFXLl1jpZXxqo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:A0A0S2Z5U3	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-16468000	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468456	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432416(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:S/hUnw+Q3wG1z3rA+Y+LJXvt/4M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q8WVV9	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468440	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432416(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:a4F4s0coAqm1d19Kgl2R8/l+Zgo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z5U3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16468000	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468424	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432148(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:neNI/e6ct3YS3jVzT6XWIQyDcdA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q8WVV9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468408	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432148(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:IF2wLf8qhyWMxYoj7vQplA0BgTI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14503	uniprotkb:A0A0S2Z5U3	intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495	intact:EBI-16468000	psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468392	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432088(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:OqvUyfmkBZOInwv6PQlz7miJtjc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14503	uniprotkb:Q8WVV9	intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468376	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432088(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:ntBrV/xXX1Bc4+KirPCiXFhoFv8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:A0A0S2Z5U3	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-16468000	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468360	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:lFaed2VIrUq3XZEeOXscngJ9kc4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q8WVV9	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468344	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:++rZAaxmSSyoR4mTJpF4UAhalF0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99836	uniprotkb:F8VVZ1	intact:EBI-447677|uniprotkb:P78397|uniprotkb:Q53XS7|uniprotkb:B4DKH8|uniprotkb:B4DKU4|uniprotkb:J3KPU4|uniprotkb:J3KQ87|uniprotkb:J3KQJ6|uniprotkb:B4DQ60|uniprotkb:B4DQ72|ensembl:ENSP00000379625|ensembl:ENSP00000498360	intact:EBI-16469141|ensembl:ENSP00000448197|ensembl:ENSP00000449553|ensembl:ENSP00000449693|ensembl:ENSP00000449859	psi-mi:myd88_human(display_long)|uniprotkb:MYD88(gene name)|psi-mi:MYD88(display_short)	psi-mi:f8vvz1_human(display_long)|uniprotkb:IRAK4(gene name)|psi-mi:IRAK4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469144	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166037.1|refseq:NP_001166039.1|refseq:NP_001166040.1|refseq:NP_002459.2|dip:DIP-31349N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034158"(toll-like receptor 8 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:2000338"("regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR034249|interpro:IPR035897|mint:Q99836|rcsb pdb:2JS7|rcsb pdb:2Z5V|rcsb pdb:3MOP|rcsb pdb:4DOM|rcsb pdb:4EO7|rcsb pdb:6I3N|rcsb pdb:7BEQ|rcsb pdb:7BER|rcsb pdb:7L6W|reactome:R-HSA-1236974|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-1810476|reactome:R-HSA-209543|reactome:R-HSA-3134963|reactome:R-HSA-5602498|reactome:R-HSA-5602680|reactome:R-HSA-5603037|reactome:R-HSA-5603041|reactome:R-HSA-6811558|reactome:R-HSA-9020702|reactome:R-HSA-975110|reactome:R-HSA-975155|reactome:R-HSA-975871|reactome:R-HSA-975138|ensembl:ENSG00000172936(gene)|ensembl:ENST00000396334(transcript)|ensembl:ENST00000650905(transcript)|go:"GO:0002238"(response to molecule of fungal origin)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005121"(Toll binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009682"(induced systemic resistance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0070976"(TIR domain binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:0050830"(defense response to Gram-positive bacterium)|entrezgene/locuslink:4615(identity)	ensembl:ENSG00000198001(gene)|ensembl:ENST00000547521(transcript)|ensembl:ENST00000550361(transcript)|ensembl:ENST00000550615(transcript)|ensembl:ENST00000552309(transcript)|go:"GO:0016301"(kinase activity)|interpro:IPR011029(DEATH-like)|entrezgene/locuslink:51135(identity)	intact:EBI-16431429(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B920s5F0eUql/jtwlByyhI7ojGI9606	rogid:tyQt66S4ehIfxE18YIVr6Ylmlak9606	rigid:QVILkOlqjXtQIStSYBQ+ZabZyKI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P49441	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-725432|ensembl:ENSP00000325423|ensembl:ENSP00000376142	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:inpp_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469125	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_001122400.1|refseq:NP_002185.1|refseq:XP_005246589.1|ensembl:ENSG00000151689(gene)|ensembl:ENST00000322522(transcript)|ensembl:ENST00000392329(transcript)|go:"GO:0004441"(inositol-1,4-bisphosphate 1-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|reactome:R-HSA-1855183|entrezgene/locuslink:3628(identity)	intact:EBI-16433613(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:nPr4mBqj4mWyNAWpbA+BY1Z8ZU49606	rigid:PK/xydskR5ISgDMbQ79JdY7CkF4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P20393	uniprotkb:P49441	intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672	intact:EBI-725432|ensembl:ENSP00000325423|ensembl:ENSP00000376142	psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym)	psi-mi:inpp_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469109	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068370.1|ensembl:ENSG00000126368(gene)|ensembl:ENST00000246672(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043197"(dendritic spine)|go:"GO:0044321"(response to leptin)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070859"(positive regulation of bile acid biosynthetic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1A6Y|rcsb pdb:1EF6|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N|entrezgene/locuslink:9572(identity)	refseq:NP_001122400.1|refseq:NP_002185.1|refseq:XP_005246589.1|ensembl:ENSG00000151689(gene)|ensembl:ENST00000322522(transcript)|ensembl:ENST00000392329(transcript)|go:"GO:0004441"(inositol-1,4-bisphosphate 1-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|reactome:R-HSA-1855183|entrezgene/locuslink:3628(identity)	intact:EBI-16430608(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606	rogid:nPr4mBqj4mWyNAWpbA+BY1Z8ZU49606	rigid:PwAXSbfGyz/hAEX1ymmifS0Eoi4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469090	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: hspd1_4"(display_short)|psi-mi:EBI-16469090(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469093	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:3329(identity)	intact:EBI-16432228(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:hhB7/gWvIqi2AaZO0SBi2IWXwio9606	rigid:yVscnBLaZq/kivevgQZnGrCS7cA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469071	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: hspd1_2"(display_short)|psi-mi:EBI-16469071(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469074	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:3329(identity)	intact:EBI-16432228(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:h9GgE/V//AvJcuqOedYq2wr49Pc9606	rigid:PDmrtgoijYIWQUUgKcL81vsKSkI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:A0A0S2Z5U3	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-16468000	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469055	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16440594(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:9bGQVleeOW5VRiK3ossnN2APJOA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:Q8WVV9	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469039	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16440594(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:ZaCwLYCOfLnWFpeH5K7YtKGVOUk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UY14-3	uniprotkb:A0A0S2Z5U3	intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295	intact:EBI-16468000	psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469020	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16440344(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:VoSVGaG0uHvirP/euLfEGmKDnEw	true	sufficient binding region:674-1097	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UY14-3	uniprotkb:Q8WVV9	intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469001	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16440344(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:mgjhHNmKKZzqo5oFO3dErjNy2Qo	true	sufficient binding region:674-1097	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:A0A0S2Z5U3	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-16468000	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468985	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438980(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:98Rdl7v1gaeTCJVn87bSctg+iPY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:Q8WVV9	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468969	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16438980(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:yU67t0qGg1IRr2FK8STnjK7hywo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:A0A0S2Z5U3	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-16468000	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468953	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438850(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:JvtnlIBDfrD6srCGlwddnIzucVg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z5U3	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16468000	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468937	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438071(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:AwTNFyfZ8etJs2GyihwDcISIKvo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:Q8WVV9	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468921	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16438071(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:L7p3ap1/F9hRe1kTAvUqEto5vF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P26440-2	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16469190|ensembl:ENSP00000498731	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:p26440-2(display_long)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469196	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	intact:EBI-2866408(isoform-parent)|ensembl:ENSG00000128928(gene)|ensembl:ENST00000650656(transcript)|entrezgene/locuslink:3712(identity)	intact:EBI-16429173(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2018/09/18	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:QjW2mNCenQf/Ih5vqq4aG6P1xUU9606	rigid:xupT8yO5GweGyqhVckdBNSqbcJ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P26440	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469174	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_002216.2|refseq:NP_001152980.1|ensembl:ENSG00000128928(gene)|ensembl:ENST00000651168(transcript)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0008470"(isovaleryl-CoA dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1IVH|reactome:R-HSA-70895|entrezgene/locuslink:3712(identity)	intact:EBI-16429173(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2018/09/18	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:GewB1Yyc2EEVepN5e1H068xpjI09606	rigid:V01dUY2LBYA0pDOhCiibH8UgbGg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z5P4	intact:EBI-16439278	intact:EBI-16469235	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z5p4_human(display_long)|uniprotkb:JMJD5(gene name)|psi-mi:JMJD5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469241	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR041667|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:79831(identity)	intact:EBI-16439577(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:7/IA0JDDT45tTJ9vbsjpiFn5GSk9606	rigid:y04mg9Om7j70bktrA8ZPaoBSIek	true	-	sufficient binding region:1-300	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-6	uniprotkb:A0A0S2Z5A4	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-16469260	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469263	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16433440(see-also)	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:cTkVOaaYUWoS6dUgmNxlyeEDSbo	true	sufficient binding region:15-513	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14498-3	uniprotkb:A0A0S2Z5A4	intact:EBI-6654703|ensembl:ENSP00000436747	intact:EBI-16469260	psi-mi:q14498-3(display_long)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469282	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131051(gene)|ensembl:ENST00000528062(transcript)|intact:EBI-395290(isoform-parent)|entrezgene/locuslink:9584(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16435466(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gEOR16XItpn4AN2H+cvwNQW+IUU9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:E2rejSS7nrL/+ovvfT8hwE5zmFY	true	sufficient binding region:136-508	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-2	uniprotkb:A0A0S2Z5A4	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-16469260	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469301	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16435982(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:Hw+S3XiHqNDuxVzCFZ5lL9SGZ/8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:A0A0S2Z5A4	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-16469260	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469317	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16437536(see-also)	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:9B5t8xjS+JgND1CChJZSmm6eLD0	true	sufficient binding region:15-530	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:A0A0S2Z5A4	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-16469260	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469336	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16440322(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:sWd4ZZwUdD0Cc53eKgU0JtB/aXU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	intact:EBI-16431876	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	-	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"ccsb isoform id: krt6a_2"(display_short)|psi-mi:EBI-16431876(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469352	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	entrezgene/locuslink:3853(identity)	intact:EBI-16433891(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:yW9Icx0fchBmUxpcpz1lpDgBoy09606	rigid:VnT0TSCNeiYE5oreHYVbSzkXmj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P02538	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469368	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3853(identity)	intact:EBI-16440858(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:feIxUFTSMnjattUda5vdGhiL9H89606	rigid:fBRLkKK7sK9U7JyNb2HH6XM9jms	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q13751	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-2529833|uniprotkb:O14947|uniprotkb:Q14733|uniprotkb:Q9UJK4|uniprotkb:Q9UJL1|uniprotkb:D3DT88|ensembl:ENSP00000348384|ensembl:ENSP00000355997|ensembl:ENSP00000375778	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:lamb3_human(display_long)|uniprotkb:Epiligrin subunit bata(gene name synonym)|uniprotkb:Kalinin subunit beta(gene name synonym)|uniprotkb:Nicein subunit beta(gene name synonym)|uniprotkb:LAMB3(gene name)|psi-mi:LAMB3(display_short)|uniprotkb:LAMNB1(gene name synonym)|uniprotkb:Laminin-5 subunit beta(gene name synonym)|uniprotkb:Laminin B1k chain(gene name synonym)|uniprotkb:Kalinin B1 chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469384	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	ensembl:ENSG00000196878(gene)|ensembl:ENST00000356082(transcript)|ensembl:ENST00000367030(transcript)|ensembl:ENST00000391911(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043256"(laminin complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:Q13751|reactome:R-HSA-1474228|reactome:R-HSA-2022090|reactome:R-HSA-2214320|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-446107|reactome:R-HSA-8874081|refseq:NP_000219.2|refseq:NP_001017402.1|refseq:NP_001121113.1|refseq:XP_005273181.1|entrezgene/locuslink:3914(identity)	intact:EBI-16435134(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:sZg1IU7enqhMRqryIrBkYRSP8/k9606	rigid:zxam11yPBqnBQzywp8c8fPR4qCE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L996	uniprotkb:A0A0S2Z3Y4	intact:EBI-10181089	intact:EBI-16469400	psi-mi:i6l996_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)	psi-mi:a0a0s2z3y4_human(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469416	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036137|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007172"(signal complex assembly)|entrezgene/locuslink:5747(identity)	go:"GO:0005886"(plasma membrane)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_001317397.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR035850|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:3932(identity)	intact:EBI-16432436(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aHSFMTSzdwboAzFgymTQXp0AiP49606	rogid://TSM44HoapvCeNP+Vtuoiu+PlM9606	rigid:oV/7ntFsyUZVpM9MmJUPQn3SWNY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23771	uniprotkb:P06239-3	intact:EBI-6664760|ensembl:ENSP00000341619|uniprotkb:Q5VWG7|uniprotkb:Q5VWG8|uniprotkb:Q96J16	intact:EBI-13287659|ensembl:ENSP00000328213	psi-mi:gata3_human(display_long)|uniprotkb:GATA3(gene name)|psi-mi:GATA3(display_short)|uniprotkb:GATA-binding factor 3(gene name synonym)	psi-mi:p06239-3(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469432	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107485(gene)|ensembl:ENST00000346208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001764"(neuron migration)|go:"GO:0001806"(type IV hypersensitivity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002520"(immune system development)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009615"(response to virus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035799"(ureter maturation)|go:"GO:0035898"(parathyroid hormone secretion)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0090102"(cochlea development)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000607"(negative regulation of cell proliferation involved in mesonephros development)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:2000703"(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation)|go:"GO:2000734"(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029521|interpro:IPR039355|rcsb pdb:4HC7|rcsb pdb:4HC9|rcsb pdb:4HCA|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-983231|go:"GO:2000683"(regulation of cellular response to X-ray)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0060676"(ureteric bud formation)|go:"GO:0061085"(regulation of histone H3-K27 methylation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0070888"(E-box binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0048589"(developmental growth)|refseq:XP_005252499.1|refseq:XP_005252500.1|refseq:NP_001002295.1|refseq:NP_002042.1|dip:DIP-61302N|entrezgene/locuslink:2625(identity)	uniprotkb:P06239-3(isoform-parent)|intact:EBI-1348(isoform-parent)|ensembl:ENSG00000182866(gene)|ensembl:ENST00000333070(transcript)|entrezgene/locuslink:3932(identity)	intact:EBI-16433643(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CHTPVKH4qSR/pDIf/vMr+kChpzc9606	rogid:AhIzJ3C93NIaoYcShniBSfH0sAI9606	rigid:8dMore1eiVDxzMNBHygQh/w34dQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23771	uniprotkb:A0A0S2Z3Y4	intact:EBI-6664760|ensembl:ENSP00000341619|uniprotkb:Q5VWG7|uniprotkb:Q5VWG8|uniprotkb:Q96J16	intact:EBI-16469400	psi-mi:gata3_human(display_long)|uniprotkb:GATA3(gene name)|psi-mi:GATA3(display_short)|uniprotkb:GATA-binding factor 3(gene name synonym)	psi-mi:a0a0s2z3y4_human(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469448	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107485(gene)|ensembl:ENST00000346208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001764"(neuron migration)|go:"GO:0001806"(type IV hypersensitivity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002520"(immune system development)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009615"(response to virus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035799"(ureter maturation)|go:"GO:0035898"(parathyroid hormone secretion)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0090102"(cochlea development)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000607"(negative regulation of cell proliferation involved in mesonephros development)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:2000703"(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation)|go:"GO:2000734"(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029521|interpro:IPR039355|rcsb pdb:4HC7|rcsb pdb:4HC9|rcsb pdb:4HCA|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-983231|go:"GO:2000683"(regulation of cellular response to X-ray)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0060676"(ureteric bud formation)|go:"GO:0061085"(regulation of histone H3-K27 methylation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0070888"(E-box binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0048589"(developmental growth)|refseq:XP_005252499.1|refseq:XP_005252500.1|refseq:NP_001002295.1|refseq:NP_002042.1|dip:DIP-61302N|entrezgene/locuslink:2625(identity)	go:"GO:0005886"(plasma membrane)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_001317397.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR035850|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:3932(identity)	intact:EBI-16433643(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CHTPVKH4qSR/pDIf/vMr+kChpzc9606	rogid://TSM44HoapvCeNP+Vtuoiu+PlM9606	rigid:mdFYt9kBXJiP1j9KmFxt0RSnGuU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:O75112-5	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16469464|ensembl:ENSP00000485389	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:o75112-5(display_long)|uniprotkb:Protein cypher(gene name synonym)|uniprotkb:Z-band alternatively spliced PDZ-motif protein(gene name synonym)|uniprotkb:LDB3(gene name)|psi-mi:LDB3(display_short)|uniprotkb:KIAA0613(gene name synonym)|uniprotkb:ZASP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469472	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	intact:EBI-1222667(isoform-parent)|ensembl:ENSG00000122367(gene)|ensembl:ENST00000623007(transcript)|entrezgene/locuslink:11155(identity)	intact:EBI-16434013(see-also)	-	isoform-comment:"Variant in position: 315:R->C (in MFM-ZASP)."	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:27Yip0E8r+OuTAennn+6T2meYQE9606	rigid:vPaTJzDvRdvTrV/QkUu24/aBfaM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UX01	uniprotkb:P43364	intact:EBI-8640839|ensembl:ENSP00000267102|uniprotkb:Q9NT09|intact:MINT-8163155|uniprotkb:Q969J4|uniprotkb:Q9NVE1|uniprotkb:Q9ULP6|uniprotkb:Q9NVU9|uniprotkb:Q96HN8|uniprotkb:Q96BY8	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	psi-mi:lmbrl_human(display_long)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)|uniprotkb:KIAA1174(gene name synonym)|uniprotkb:LIMR(gene name synonym)|uniprotkb:Limb region 1 protein homolog-like(gene name synonym)|uniprotkb:Lipocalin-1-interacting membrane receptor(gene name synonym)|uniprotkb:UNQ458/PRO783(orf name)	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469488	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139636(gene)|ensembl:ENST00000267102(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR008075(Lipocalin-1 receptor)|refseq:NP_001287679.1|refseq:NP_001287680.1|refseq:NP_060583.2|entrezgene/locuslink:55716(identity)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	intact:EBI-16434479(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hPTmAiiZhDiXNLvPvM9io+B6Kqs9606	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rigid:3PCjy4HhhiMVBtQMJFlGP8nC94E	true	-	sufficient binding region:111-429	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	uniprotkb:A0A0S2Z5M5	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	intact:EBI-16469507	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:a0a0s2z5m5_human(display_long)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469510	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR008075(Lipocalin-1 receptor)|entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:VN/wMhanEGUoiY78scdDRr5a2Ys9606	rigid:36lT4Sak9mM0vbjcqzC+KRMoeYM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	uniprotkb:Q6UX01-3	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	intact:EBI-16469529|ensembl:ENSP00000447329	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:q6ux01-3(display_long)|uniprotkb:Limb region 1 protein homolog-like(gene name synonym)|uniprotkb:Lipocalin-1-interacting membrane receptor(gene name synonym)|uniprotkb:UNQ458/PRO783(orf name)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)|uniprotkb:KIAA1174(gene name synonym)|uniprotkb:LIMR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469538	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	ensembl:ENSG00000139636(gene)|ensembl:ENST00000547382(transcript)|intact:EBI-8640839(isoform-parent)|entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:j+AtYdU3X6My8X28WV4PPrTgIXw9606	rigid:TxbwyjO2qdNc46eiRUBGaNqWL60	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	intact:EBI-16469557	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	-	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"ccsb isoform id: lmbr1l_5"(display_short)|psi-mi:EBI-16469557(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469560	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:zpgJSFTm9M5ifWUxZG6m5y5PJSc9606	rigid:MqUNjQLoc3UCaM8ajRag+KkciFM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:O15116	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469579	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body)|entrezgene/locuslink:27257(identity)	intact:EBI-16434025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606	rigid:ylmuTENcglrvN8kvbbsELy/J0tc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z5P8	intact:EBI-16439278	intact:EBI-16469212	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z5p8_human(display_long)|uniprotkb:JMJD5(gene name)|psi-mi:JMJD5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469219	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR041667|refseq:XP_016879165.1|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|entrezgene/locuslink:79831(identity)	intact:EBI-16439577(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:wBYujY+67BXE12wI+WLXxpSjeFU9606	rigid:prrEDH9RNJuC1bV1rgsFvceYnA0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NRG1	intact:EBI-16469675	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	-	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"ccsb isoform id: mcmbp_3"(display_short)|psi-mi:EBI-16469675(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469694	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	entrezgene/locuslink:79892(identity)	intact:EBI-16433217(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	rogid:jlwzNIgLbSOvwlOEzQbiAfIAaM89606	rigid:47oIqZDLyHmWxpqlk0PzyxDGFKQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04424	intact:EBI-16469675	intact:EBI-750131|uniprotkb:Q6LDS5|uniprotkb:Q96HS2|uniprotkb:E7EMI0|uniprotkb:E9PE48|ensembl:ENSP00000307188|ensembl:ENSP00000378741	-	psi-mi:arly_human(display_long)|uniprotkb:Arginosuccinase(gene name synonym)|uniprotkb:ASL(gene name)|psi-mi:ASL(display_short)	psi-mi:"ccsb isoform id: mcmbp_3"(display_short)|psi-mi:EBI-16469675(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469678	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000039.2|refseq:NP_001020114.1|refseq:NP_001020115.1|ensembl:ENSG00000126522(gene)|ensembl:ENST00000304874(transcript)|ensembl:ENST00000395332(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004056"(argininosuccinate lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000362(Fumarate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|interpro:IPR029419|rcsb pdb:1AOS|rcsb pdb:1K62|reactome:R-HSA-70635|entrezgene/locuslink:435(identity)	entrezgene/locuslink:79892(identity)	intact:EBI-16433007(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/jjoPEHb9KDFHkiMHccy73q2dGc9606	rogid:jlwzNIgLbSOvwlOEzQbiAfIAaM89606	rigid:o22mfKaQ3PC/gBanelJQGN7quF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P33993	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469659	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16438686(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:UKrOJI8cGWl4ds7kKhcu/4qAO38	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BTE3-2	intact:EBI-16431221	intact:EBI-9384556|ensembl:ENSP00000358073	-	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"ccsb isoform id: mcm7_2"(display_short)|psi-mi:EBI-16431221(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469643	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	entrezgene/locuslink:4176(identity)	intact:EBI-16435274(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_2 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	rogid:SqFBX8NXgEirtGEAtrDOEdPxPU89606	rigid:dIXZQfAFmfMP0OZbwm7bvY/ZzL0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NQM4	uniprotkb:P33993	intact:EBI-10239299|uniprotkb:Q86WE1|uniprotkb:D3DUX5|ensembl:ENSP00000337757|ensembl:ENSP00000361531|ensembl:ENSP00000441930	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:daaf6_human(display_long)|uniprotkb:DNAAF6(gene name)|psi-mi:DNAAF6(display_short)|uniprotkb:CXorf41(gene name synonym)|uniprotkb:PIH1 domain-containing protein 3(gene name synonym)|uniprotkb:PIH1D3(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-97(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469627	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001162625.1|refseq:NP_775765.1|refseq:XP_011529157.1|ensembl:ENSG00000080572(gene)|ensembl:ENST00000336387(transcript)|ensembl:ENST00000372453(transcript)|ensembl:ENST00000535523(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070286"(axonemal dynein complex assembly)|interpro:IPR026697|interpro:IPR041442|entrezgene/locuslink:139212(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16434369(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9mwmzVB9qiOuJQxcSddINet79iE9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:ai4LQIpw9uje25/3lxDN6Y4qQ1U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43360	uniprotkb:P33993	intact:EBI-1045155|uniprotkb:A8IF93|uniprotkb:Q6NW44|ensembl:ENSP00000329199|ensembl:ENSP00000480637	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:maga6_human(display_long)|uniprotkb:MAGE-6 antigen(gene name synonym)|uniprotkb:MAGE3B antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.6(gene name synonym)|uniprotkb:MAGEA6(gene name)|psi-mi:MAGEA6(display_short)|uniprotkb:MAGE6(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469611	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005354.1|refseq:NP_787064.1|ensembl:ENSG00000197172(gene)|ensembl:ENST00000329342(transcript)|ensembl:ENST00000616035(transcript)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030097|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4105(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16431223(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ag4IF8+k8aF+zuiB7NwjRrGGH6E9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:MXP+YjwUgwSzlYx7BcLr7pVYGAA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P62310	intact:EBI-16434023	intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0	-	psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)	psi-mi:"ccsb isoform id: lsm1_3"(display_short)|psi-mi:EBI-16434023(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469595	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N|entrezgene/locuslink:27258(identity)	entrezgene/locuslink:27257(identity)	intact:EBI-16436871(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606	rogid:0XwAa+GObi6yt/UTcyBxxvUrqW09606	rigid:+08TQ0rQJoHqBsOS+S63ewpE1u4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q02078-6	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16437973|ensembl:ENSP00000337202|ensembl:ENSP00000453441	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:q02078-6(display_long)|uniprotkb:Serum response factor-like protein 1(gene name synonym)|uniprotkb:MEF2A(gene name)|psi-mi:MEF2A(display_short)|uniprotkb:MEF2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469710	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000068305(gene)|ensembl:ENST00000338042(transcript)|ensembl:ENST00000557785(transcript)|intact:EBI-2656305(isoform-parent)|entrezgene/locuslink:4205(identity)	intact:EBI-16431407(see-also)	-	isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 98.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:amqLoUTbFoxuByvSeiZrS7zXJRc9606	rigid:I/4qsh5j5GiGjRPFEPIVkcP/OzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13164	intact:EBI-16469726	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	-	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"ccsb isoform id: mef2a_5"(display_short)|psi-mi:EBI-16469726(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469729	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	entrezgene/locuslink:4205(identity)	intact:EBI-16437979(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:Zyb8qTETXCdDyqhP6DLA9B0ZWyU9606	rigid:q8nRbJJ6IilcNnrH6E4vFcgWhKM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	intact:EBI-16469745	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	-	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469748	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16429183(see-also)|intact:EBI-16429193(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:c+4pheGSd14rM4+J6fXYk3Kem9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	intact:EBI-16469745	intact:EBI-10172526|ensembl:ENSP00000413976	-	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469765	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16429468(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:oCPVLDzjCDnJhJohx2tDLNvaj4w	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	intact:EBI-16469745	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	-	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469784	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16430823(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:+pV9nU6WznCfgBsxc2xb08a0HdE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469745	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469800	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16432238(see-also)|intact:EBI-16432248(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:/Fl+Uydtdbu/uiwOEptFbxB178k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	intact:EBI-16469745	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	-	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469817	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16432374(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:2pQI36dP6mTQO95RlD+F8DWxi9s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:Q9H7H0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469833	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0|entrezgene/locuslink:64745(identity)	intact:EBI-16432374(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606	rigid:5sB+y8Q6ab17+OOk+oAn/zIJcww	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	intact:EBI-16469745	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	-	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469849	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16433057(see-also)|intact:EBI-16433067(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:APpXW2U8lKd9qXsNeDYVnZbcjLA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	intact:EBI-16469745	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	-	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469866	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16435144(see-also)|intact:EBI-16435154(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:BGoFHOIeIMEYX0Hpv1Ro1DzAAgE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	intact:EBI-16469745	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	-	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469883	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16436091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:dQ4U+TGlgqigz4PY5SEwdD3l05I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16469745	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469899	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16439599(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:yQrUCLhR275/2NMgWMcRth7S6/s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9H7H0	intact:EBI-16439278	intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469915	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0|entrezgene/locuslink:64745(identity)	intact:EBI-16439599(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606	rigid:20mDHO3cOxGtL6l+081R7o7eaT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H892-2	uniprotkb:A0A0S2Z5W4	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	intact:EBI-16469931	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:a0a0s2z5w4_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469937	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	interpro:IPR026175|entrezgene/locuslink:145282(identity)	intact:EBI-16440740(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	rogid:3ejDpH+ibC5NXUABPjgilPVDuOA9606	rigid:01j3he4KV8yuWO6WFv9Jckhm0Ns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H892-2	uniprotkb:A0A0S2Z674	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	intact:EBI-16469953	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:a0a0s2z674_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469959	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	interpro:IPR026175|entrezgene/locuslink:145282(identity)	intact:EBI-16440740(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	rogid:W+FeO28V8BN0eE1ebJT62PET4eQ9606	rigid:svcsSDHSgwkryM2lgzWuJbqTeEQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	intact:EBI-16439609	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	-	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"ccsb isoform id: mlf1_5"(display_short)|psi-mi:EBI-16439609(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469975	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	entrezgene/locuslink:4291(identity)	intact:EBI-16434491(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:ZMtj2W+VOGl/FinhPqOSkd7clFg9606	rigid:RuwsOkEq4H9Sz3fz+9GZhyWyRYM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:P58340	intact:EBI-16439278	intact:EBI-721328|intact:EBI-767466|uniprotkb:E9PEU9|uniprotkb:Q2TLE5|uniprotkb:Q8N8F8|uniprotkb:Q96MH1|uniprotkb:Q2TLE3|ensembl:ENSP00000348157	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:mlf1_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 1(gene name synonym)|uniprotkb:MLF1(gene name)|psi-mi:MLF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469994	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_071888.1|refseq:NP_001182361.1|refseq:NP_001182362.1|refseq:NP_001182363.1|refseq:XP_011511154.1|refseq:NP_001123628.1|refseq:NP_001123629.1|ensembl:ENSP00000348157|ensembl:ENST00000359117|ensembl:ENSP00000352025|ensembl:ENST00000392822|ensembl:ENSP00000376568|ensembl:ENST00000469452|ensembl:ENSP00000418595|ensembl:ENST00000471745|ensembl:ENSP00000420134|ensembl:ENST00000477042|ensembl:ENSP00000419637|ensembl:ENST00000478894|ensembl:ENSP00000417777|ensembl:ENST00000482628|ensembl:ENSP00000417141|ensembl:ENST00000484955|ensembl:ENSP00000417835|ensembl:ENST00000618075|ensembl:ENSP00000484169|ensembl:ENST00000651874|ensembl:ENSP00000498363|refseq:XP_011511155.1|refseq:XP_005247537.1|ensembl:ENSG00000178053(gene)|ensembl:ENST00000355893(transcript)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR019376|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6Y8E|entrezgene/locuslink:4291(identity)	intact:EBI-16439611(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:czY64xaocTjgRFAtZU19jvH4MIo9606	rigid:sFu5Ult2L5Eh5EF0jhwiWPkqwFs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z414	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16470010	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z414_human(display_long)|uniprotkb:MNAT1(gene name)|psi-mi:MNAT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470013	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0005694"(chromosome)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|entrezgene/locuslink:4331(identity)	intact:EBI-16438504(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:A3QD1f7tkTcEwQiMnqHb9RjcmYQ9606	rigid:KtcEI8qUAWlXyqSkM6pgDWn5kmI	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16434391	uniprotkb:Q13875-3	-	intact:EBI-12013470|ensembl:ENSP00000373261|ensembl:ENSP00000388148|ensembl:ENSP00000401312|ensembl:ENSP00000405549|ensembl:ENSP00000409730	psi-mi:"ccsb orf id: 4214"(display_short)|psi-mi:EBI-16434391(display_long)	psi-mi:q13875-3(display_long)|uniprotkb:MOBP(gene name)|psi-mi:MOBP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470032	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:51322(identity)	intact:EBI-10230628(isoform-parent)|ensembl:ENSG00000168314(gene)|ensembl:ENST00000383754(transcript)|ensembl:ENST00000415443(transcript)|ensembl:ENST00000428261(transcript)|ensembl:ENST00000447324(transcript)|ensembl:ENST00000452959(transcript)|uniprotkb:Q13875-3(isoform-parent)|uniprotkb:Q13875(isoform-parent)|entrezgene/locuslink:4336(identity)	intact:EBI-16434393(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606	rogid:5ggi9FWhAQgAnqMbLGQbSC+v4049606	rigid:sMEq5sDRgc1BIo/pVMobTPUDwwY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:A0A0S2Z469	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-16470048	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:a0a0s2z469_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470055	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR007248(Mpv17/PMP22)|entrezgene/locuslink:4358(identity)	intact:EBI-16440288(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:JSwozIrhGB4JPZnxPDsiRGVjL+89606	rigid:8lLiIwAHlHeqFUi3K8+gmslds10	true	sufficient binding region:37-351	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q03426	uniprotkb:F5H8H2	intact:EBI-740630|ensembl:ENSP00000228510|ensembl:ENSP00000443551	intact:EBI-16470096|ensembl:ENSP00000376487|ensembl:ENSP00000486846	psi-mi:kime_human(display_long)|uniprotkb:MVK(gene name)|psi-mi:MVK(display_short)	psi-mi:f5h8h2_human(display_long)|uniprotkb:MVK(gene name)|psi-mi:MVK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470118	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288111.1|ensembl:ENSG00000110921(gene)|ensembl:ENST00000228510(transcript)|ensembl:ENST00000539575(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004496"(mevalonate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006205(Mevalonate kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|rcsb pdb:2R3V|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_000422.1|refseq:NP_001107657.1|refseq:XP_016874803.1|entrezgene/locuslink:4598(identity)	ensembl:ENSG00000110921(gene)|ensembl:ENST00000392727(transcript)|ensembl:ENST00000625889(transcript)|go:"GO:0004496"(mevalonate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR006204(GHMP kinase)|interpro:IPR006205(Mevalonate kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_001288111.1|refseq:XP_016874802.1|entrezgene/locuslink:4598(identity)	intact:EBI-16433177(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aNoNx1GxznUy5Sha8pg9q6SK5lw9606	rogid:QARRM7Sfrh7jiH0zmK2l+jxt+QI9606	rigid:uqdqbhKldFKUClmHgdG1q0l8Ass	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:A0A0S2Z466	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-16470074	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:a0a0s2z466_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470077	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	entrezgene/locuslink:4358(identity)	intact:EBI-16440288(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:wN9MhGWk8flcmGtr/0RWiUlpcEM9606	rigid:oqCM61cj5e7y3d1o4ARPwMmX9UU	true	sufficient binding region:37-351	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z442	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16435864	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470699	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:jSjRfyqDbFwiXsH6TXLS2TQQyA4	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z3Y6	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16435852	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470680	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:WuDbM+/C6DnUkGotxqXQll9zlvA	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z3Z2	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16470607	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470664	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:Xb9uUHPqxlN/6C8piYbCyb381t4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z442	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16435864	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470648	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:N4j7TlsIbAF5/Cy9XQP72ATsh9Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z3Y6	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16435852	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470632	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:GoqpYqO+OMp0FHa5qk9j488CwkA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z3Z2	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16470607	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470616	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:YTLpq1Knw/S8c88BWpHrRytf5lk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z442	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16435864	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470591	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:4kuxEZ0wVittNCmgL7YpvAJonME	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z3Y6	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16435852	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470575	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:OIo+ShkxGvm5lfSMs4eBirlq7P0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:E7ERP6	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470559	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16438716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:UTKF+NwN5khzlfjxhnrXC8lSsAw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	uniprotkb:E7ERP6	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470543	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16432612(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:SMSIHxvJ8eIs+x5jb3fFHgrL2As	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A6PVS8	uniprotkb:E7ERP6	intact:EBI-10184751|uniprotkb:Q6P5P7|uniprotkb:A6PVS9|uniprotkb:Q8WUE0|uniprotkb:Q6ZMV4|ensembl:ENSP00000346414|ensembl:ENSP00000378524	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lriq3_human(display_long)|uniprotkb:LRRIQ3(gene name)|psi-mi:LRRIQ3(display_short)|uniprotkb:LRRC44(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 44(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470524	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001099129.1|ensembl:ENSG00000162620(gene)|ensembl:ENST00000354431(transcript)|ensembl:ENST00000395089(transcript)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|entrezgene/locuslink:127255(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16431818(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tKMDvvd6Ewj8c0zCALo+pv6+el89606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:Z1GXHWl+OzewT4eDVnDB6NPzmlk	true	sufficient binding region:404-624	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:E7ERP6	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470508	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16430556(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:Vlh3x4+vOEhpTDE3+X3NiJW8j8E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13094	uniprotkb:E7ERP6	intact:EBI-346946|uniprotkb:Q53XV4|uniprotkb:A8KA25|ensembl:ENSP00000046794	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lcp2_human(display_long)|uniprotkb:LCP2(gene name)|psi-mi:LCP2(display_short)|uniprotkb:SH2 domain-containing leukocyte protein of 76 kDa(gene name synonym)|uniprotkb:SLP-76 tyrosine phosphoprotein(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470492	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005556.1|dip:DIP-31812N|ensembl:ENSG00000043462(gene)|ensembl:ENST00000046794(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036398"(TCR signalosome)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036860|mint:Q13094|rcsb pdb:1H3H|rcsb pdb:1YWO|rcsb pdb:2EAP|rcsb pdb:2ROR|rcsb pdb:6ZCJ|reactome:R-HSA-114604|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|entrezgene/locuslink:3937(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16430051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:lZa+nAuqvGDrNe3Jhxn/JQaU5ug9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:mFHT8DhRg5rm3Ofb3ypiuwbjCcE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P48023	uniprotkb:A0A0S2Z4E4	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-16432934	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470476	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|entrezgene/locuslink:356(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16438840(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:uAFKSL/tdogltHdlU75kSFmdTh8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P48023	uniprotkb:P16333	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470460	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|entrezgene/locuslink:356(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16438840(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:4wlsxTeTgH4bxnTfUv4IhlAUSdU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P16333	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470443	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16438696(see-also)|intact:EBI-16438706(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:x9YY/TRt5pxM+zUMiwe6vlUM2OY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60504	uniprotkb:A0A0S2Z4E4	intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4	intact:EBI-16432934	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470427	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|entrezgene/locuslink:10174(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436478(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:Wf1uzrybzAXR1LzrSPjLOkeI7vQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60504	uniprotkb:P16333	intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470411	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|entrezgene/locuslink:10174(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436478(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:I4uCeo4E/G8vGrD0IMgM7xlXbDc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:P16333	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470395	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436448(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:eDeiXjBy+He+BuOAMKbvG6mviMU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:A0A0S2Z4E4	-	intact:EBI-16432934	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470379	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436266(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:jE/cw+SX7GCVty4cbfcqtDzUYdo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:P16333	-	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470363	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436266(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:GJPGM470jq0/0dfrDmntV0/qtY4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:B7ZLH0	uniprotkb:A0A0S2Z4E4	intact:EBI-10220102|intact:EBI-11975495|intact:EBI-12742387	intact:EBI-16432934	psi-mi:b7zlh0_human(display_long)|uniprotkb:FAM22F(gene name)|psi-mi:FAM22F(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470347	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024309|interpro:IPR024310|entrezgene/locuslink:54754(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0MIH/bAcmcr+6BUiuF4G+9qCEEE9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:aGXhP/KV6A4wlPTFn+r36fpgAZw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:B7ZLH0	uniprotkb:P16333	intact:EBI-10220102|intact:EBI-11975495|intact:EBI-12742387	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:b7zlh0_human(display_long)|uniprotkb:FAM22F(gene name)|psi-mi:FAM22F(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470331	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024309|interpro:IPR024310|entrezgene/locuslink:54754(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0MIH/bAcmcr+6BUiuF4G+9qCEEE9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:DeMqfVFzzvr3oPz65o2pJ0gpslo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z4E4	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16432934	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470315	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16434569(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:CenXYIo74famgMzD41k/PsIs35o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:P16333	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470299	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16434569(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:BOXpuyxBW2RxwkpFnIt9wPZj5xA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43281-2	uniprotkb:P16333	intact:EBI-11525448|ensembl:ENSP00000340607	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470282	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)|entrezgene/locuslink:10278(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16432924(see-also)|intact:EBI-16432941(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:Ue22dEliW3KgLlZrqlU1CDNleUc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:A0A0S2Z4E4	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-16432934	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470266	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16429342(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:j4wkcZae4jxzlwhg2a0wp2/w6tQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:P16333	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470250	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16429342(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:lqCI+ofXwzz8oM7+qVUNjwqgiuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92845	intact:EBI-16470212	intact:EBI-954040|ensembl:ENSP00000354560|uniprotkb:Q8NHU7|uniprotkb:Q9H416|uniprotkb:B2RDL1|uniprotkb:B1AKU4|uniprotkb:B7Z8A3|uniprotkb:F5H591|uniprotkb:B1AKU5	-	psi-mi:kifa3_human(display_long)|uniprotkb:Smg GDS-associated protein(gene name synonym)|uniprotkb:KIFAP3(gene name)|psi-mi:KIFAP3(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:KIF3AP(gene name synonym)	psi-mi:"ccsb isoform id: ncf2_3"(display_short)|psi-mi:EBI-16470212(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470234	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000075945(gene)|ensembl:ENST00000361580(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR008658(Kinesin-associated)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-1445148|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|reactome:R-HSA-2132295|reactome:R-HSA-5620924|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|refseq:NP_001191443.1|refseq:NP_001191445.1|refseq:NP_001191446.1|refseq:NP_055785.2|entrezgene/locuslink:22920(identity)	entrezgene/locuslink:4688(identity)	intact:EBI-16432208(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pEcMuA/HlGJKpLQzlt1/R00TZ3Q9606	rogid:XHifaKiQX9T73M8hI3zbprOvASg9606	rigid:gRX/2d+g9jgtNS4XYuuN0OtCSok	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	intact:EBI-16470212	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"ccsb isoform id: ncf2_3"(display_short)|psi-mi:EBI-16470212(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470215	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:4688(identity)	intact:EBI-16431890(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:XHifaKiQX9T73M8hI3zbprOvASg9606	rigid:mzuItcr2fPE1sjLqbGj9Mu5ukUs	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12814	uniprotkb:Q9UBF9	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470196	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|entrezgene/locuslink:87(identity)	go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179|entrezgene/locuslink:9499(identity)	intact:EBI-16433911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606	rigid:bPkL3/qVP9rAJ+56DZMs54ZxeYs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z429	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16470161|ensembl:ENSP00000498474	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z429_human(display_long)|uniprotkb:MXI1(gene name)|psi-mi:MXI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470180	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	ensembl:ENSG00000119950(gene)|ensembl:ENST00000651557(transcript)|entrezgene/locuslink:4601(identity)	intact:EBI-16439829(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:GxWoSYidUugRrliIv8jOCRLaqec9606	rigid:We5nCqyAcseJwfFSxlKThfrGeRs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z429	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16470161|ensembl:ENSP00000498474	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z429_human(display_long)|uniprotkb:MXI1(gene name)|psi-mi:MXI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470164	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	ensembl:ENSG00000119950(gene)|ensembl:ENST00000651557(transcript)|entrezgene/locuslink:4601(identity)	intact:EBI-16436117(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:GxWoSYidUugRrliIv8jOCRLaqec9606	rigid:+byfwSBoGfuWEiylGHDnE40/CV0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z3Y6	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16435852	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470753	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:xIi4jLqGVri0ZDYas3uvhZkiyAE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:Q99608	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470737	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606	rigid:F0O+chgUWIVbxDe6PC02n/pi9kM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z3Z2	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16470607	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470718	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:5woGWhpP0CAQzSXoPaX+o/YYnsU	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z3Z2	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16470607	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470992	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:9ecBaKx8wUYyC8iQA4YqcWCZXsY	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z442	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16435864	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470973	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:tcH28S8R7Ptj9D9vKthA5Fmxs1s	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z3Y6	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16435852	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470954	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:uZ7mhNZJ7A83Wa2NH/CFzgrmP9I	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16470607	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470935	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:WQ6UrZX4pCLZ6NDfN6Wy0gdFkZw	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z442	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16435864	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470916	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:/+yoHs1uVYi535kxEHc07BQnGAg	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16435852	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470897	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:RuBM0BsVo6w8+UpQ5FFd+yDPXoo	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z3Z2	-	intact:EBI-16470607	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470881	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:qPyYNf3AW/o45LnJgoaqQtGMh/c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z442	-	intact:EBI-16435864	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470865	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7KfI/IuxpOVxNsQnM+rFT+OqMFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z3Y6	-	intact:EBI-16435852	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470849	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:0cd2qAiRvZB5gz4DYRNYLlVpPdQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z3Z2	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16470607	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470833	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:iuDRKMAIvngxSYEmJd9FucPNML4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z442	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16435864	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470817	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:2R8mLyLilSQ8PzxNivVTUxy1Jcs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z3Y6	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16435852	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470801	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:N8UsnHnLD2V5Yvg3pKpJxC/YKqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z3Z2	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16470607	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470785	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:ShScts8C1x7m12Qnrh19n2ggep4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z442	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16435864	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470769	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:vbODVokgUFMGiO+NXwcesmVGLoE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16470607	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471440	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:e+8ppS7I8y+QjONDJF0qi6zD+yI	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z442	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16435864	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471048	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:06FbNpECo08K4ooOSd9T7gkz45s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z3Z2	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16470607	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471064	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:aEw8vlMRdLtPsdTUtL2KCsyBCzY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z3Y6	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16435852	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471080	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:Liqj0Ux345wGV+oUgnf+BiIWHnk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z442	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16435864	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471096	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7tKVcq/DsQho2jq5cVGNSsRdNmQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z3Z2	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16470607	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471112	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:RHTJT2pyAVS5RjL1jkpF5wDkHzo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z3Y6	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16435852	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471128	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:peJopJ5DCJxPIP9eoi34XYmyL/w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z442	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16435864	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471144	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:Xc7a+I1GsQMmOQz2E6An9nKuDDM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z3Z2	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16470607	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471160	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:u2NqjNKAFDrBTFN17/yCl0lw8zI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z3Y6	-	intact:EBI-16435852	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471176	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:B5fg2g+1/hWoGsxKwS5gB6HuaZ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z442	-	intact:EBI-16435864	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471192	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:hZ83uoTR5BFLbqnXFrvLuEdU8+Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z3Z2	-	intact:EBI-16470607	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471208	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:eCMl4DnwjTG3V1AhgAmfP8CXyAE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z4N8	intact:EBI-16429055	intact:EBI-10181968|uniprotkb:Q5JPA9|uniprotkb:Q5EBL3|uniprotkb:A0AV13|uniprotkb:B4DUD3|ensembl:ENSP00000332170	-	psi-mi:p4ha3_human(display_long)|uniprotkb:P4HA3(gene name)|psi-mi:P4HA3(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3(gene name synonym)|uniprotkb:UNQ711/PRO1374(orf name)	psi-mi:"ccsb isoform id: ndn_2"(display_short)|psi-mi:EBI-16429055(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471224	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275677.1|refseq:NP_878907.1|ensembl:ENSG00000149380(gene)|ensembl:ENST00000331597(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|reactome:R-HSA-1650814|entrezgene/locuslink:283208(identity)	entrezgene/locuslink:4692(identity)	intact:EBI-16435854(see-also)|intact:EBI-16435866(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:d1yT0nxg2GYPUs3YnYr4MkodoAU9606	rogid:3/K9NpgPU43gRAJpUk7hAthiupg9606	rigid:xH+hDsYeO4A66g5TJ7EKs7XBREw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z4N8	uniprotkb:A0A0S2Z3Z2	intact:EBI-10181968|uniprotkb:Q5JPA9|uniprotkb:Q5EBL3|uniprotkb:A0AV13|uniprotkb:B4DUD3|ensembl:ENSP00000332170	intact:EBI-16470607	psi-mi:p4ha3_human(display_long)|uniprotkb:P4HA3(gene name)|psi-mi:P4HA3(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3(gene name synonym)|uniprotkb:UNQ711/PRO1374(orf name)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471241	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275677.1|refseq:NP_878907.1|ensembl:ENSG00000149380(gene)|ensembl:ENST00000331597(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|reactome:R-HSA-1650814|entrezgene/locuslink:283208(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435854(see-also)|intact:EBI-16435866(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:d1yT0nxg2GYPUs3YnYr4MkodoAU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:vJmNkxCaD9AB4v1X17w+jg+SX/g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z3Y6	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16435852	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471258	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:AgCCJLUnduhIDoGJIbH8wVF646w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z442	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16435864	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471274	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:FTrbG0AueCyEW+GgOfjieFqqRoc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z3Z2	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16470607	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471290	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:vH7e01MRnuWDuiMOuZXGkHKI6XM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z3Y6	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16435852	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471306	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:V9mXo3hkQfeZjGJNjrnB38cMbCc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z442	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16435864	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471322	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:m6XiPoCb8/HojF7eoWUgaDD92XM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z3Z2	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16470607	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471338	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:PFF6wCF50EPVQZxAGojaafO+lAs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z3Y6	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16435852	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471516	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:Hr1GjDtiDD55g1ntJJTXFLKboDY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z3Z2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16470607	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471497	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:qe5/7IhbXMNx7a7SBBoJcYMjIgk	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z442	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16435864	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471478	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:Q1CiV2ABAf0ewp332ott921uKmw	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z3Y6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16435852	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471459	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:6FVyLEzkeikI8kbrexzbhQcam74	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z3Y6	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16435852	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471032	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:37DBiLChfJ+UBRTYncymw4krzRw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z442	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16435864	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471421	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:pOaR2PPXAgKBIE16pFKKltITeZg	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16435852	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471402	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:bHrUnHclUs5jhzhQ69Vtxpb1qtM	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:A0A0S2Z442	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-16435864	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471386	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:VxSXjE4wMZN5XOh9B8/nNncbFAA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:A0A0S2Z3Y6	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-16435852	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471370	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:RJ3Z27h+TApsYKOxHcrcRDijYX8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:Q99608	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471354	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606	rigid:e8Y5pNDzRW8thoBokvAfadbTYIs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z442	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16435864	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471532	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7Yicyok3J9X9AqzSVhv7EWfSVtE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BQQ3	uniprotkb:I6L9F6	intact:EBI-2561458|uniprotkb:Q3SYG7|uniprotkb:Q96H42|uniprotkb:Q8N272|uniprotkb:B3KWC8|ensembl:ENSP00000313869	intact:EBI-10178578|intact:EBI-21999896	psi-mi:gors1_human(display_long)|uniprotkb:GORASP1(gene name)|psi-mi:GORASP1(display_short)|uniprotkb:GOLPH5(gene name synonym)|uniprotkb:GRASP65(gene name synonym)|uniprotkb:Golgi reassembly-stacking protein of 65 kDa(gene name synonym)|uniprotkb:Golgi peripheral membrane protein p65(gene name synonym)|uniprotkb:Golgi phosphoprotein 5(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471845	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114105.1|refseq:NP_001265718.1|refseq:NP_001265719.1|ensembl:ENSG00000114745(gene)|ensembl:ENST00000319283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:4REY|rcsb pdb:6G8T|rcsb pdb:6G8W|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|entrezgene/locuslink:64689(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431564(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gCTXn0H+UPamtVxyvChrMrcQvCA9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:DhJtcihLIRS5IOBuY2fwRZB7o/I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z3Y6	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16435852	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471564	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:L63AWUaZ3D8IxO+R2hYNjYxLQUA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z442	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16435864	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471580	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:ps/0XkdLC04mDDNvhYbsHi/3ZjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z3Z2	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16470607	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471596	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:7+rowNxaDGFRYy/hGzu2lIbCb+g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z3Y6	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16435852	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471612	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:7z+v8/JSsMFCR4gWeQxZQJbVD6I	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z442	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16435864	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471631	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:cXAj0FINYnsqmRG96OYLX6wuXKo	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z3Z2	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16470607	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471650	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:xfXGKJ58Y01Q83U9AwsLKHeShv4	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z3Y6	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16435852	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471669	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:k+VUn7DWy+h7HoOB2ikhqBSsq4Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z442	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16435864	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471685	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:hxoe3gEUnTjYpC3OZX/0lg6JhoY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z3Z2	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16470607	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471701	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:sC7wJQRTHctX69GRJRcDOYPPOTs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16435852	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471717	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:qdJM4ej6WvLabEGLiLf5aKPQyWk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z442	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16435864	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471733	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:+HCzlLeEAOP8NlDPcUGkpjhnz7s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16470607	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471749	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:gbyyLawO06xWFds+nmZeHgI552g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HR9-2	uniprotkb:Q9ULP0	intact:EBI-14065960|ensembl:ENSP00000233596	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:q96hr9-2(display_long)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471765	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96HR9-2(isoform-parent)|intact:EBI-750345(isoform-parent)|ensembl:ENSG00000115255(gene)|ensembl:ENST00000233596(transcript)|entrezgene/locuslink:92840(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16433207(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YbC7anRtL9P0N9fSlSCGcFjb6yk9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:3Srcpa/KoPZf1X73TBB7G128U9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:Q9ULP0	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471781	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16434190(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:PQvYRWtCv7LBKSjuANpFJemZWaQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q9ULP0	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471797	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16440024(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:Whl1LFBMHS1e0hKwYCPAPHFExlo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:I6L9F6	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-10178578|intact:EBI-21999896	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471813	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16429652(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:60YrFHcyh/IuhDlXROG86Rww+ZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P17661	uniprotkb:I6L9F6	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-10178578|intact:EBI-21999896	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471829	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|entrezgene/locuslink:1674(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16430919(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:U3N9F/Nm/jKEf3xoRz7ivTa+OA4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z3Z2	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16470607	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471548	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:FM0lsi06TLZ9lpAj6yZ0mnKyB14	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P63098	uniprotkb:Q08209	intact:EBI-915984|uniprotkb:B5MDU4|uniprotkb:P06705|uniprotkb:P15117|uniprotkb:Q08044|uniprotkb:Q53SL0|uniprotkb:B2RC10|ensembl:ENSP00000234310	intact:EBI-352922|uniprotkb:Q8TAW9|uniprotkb:A8K3B7|uniprotkb:B5BUA2|uniprotkb:A1A441|uniprotkb:A8W6Z7|ensembl:ENSP00000378323|uniprotkb:A8W6Z8	psi-mi:canb1_human(display_long)|uniprotkb:PPP3R1(gene name)|psi-mi:PPP3R1(display_short)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit 1(gene name synonym)|uniprotkb:Protein phosphatase 3 regulatory subunit B alpha isoform 1(gene name synonym)	psi-mi:pp2ba_human(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472290	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000936.1|dip:DIP-6096N|ensembl:ENSG00000221823(gene)|ensembl:ENST00000234310(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007507"(heart development)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0042383"(sarcolemma)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|mint:P63098|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2P6B|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4OR9|rcsb pdb:4ORA|rcsb pdb:4ORC|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|reactome:R-HSA-111447|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|entrezgene/locuslink:5534(identity)	go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:Q08209|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2JOG|rcsb pdb:2JZI|rcsb pdb:2P6B|rcsb pdb:2R28|rcsb pdb:2W73|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4Q5U|rcsb pdb:5C1V|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6UUQ|reactome:R-HSA-180024|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|reactome:R-HSA-2025928|refseq:NP_000935.1|refseq:NP_001124163.1|refseq:NP_001124164.1|go:"GO:0043197"(dendritic spine)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000138814(gene)|ensembl:ENST00000394854(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042383"(sarcolemma)|dip:DIP-6095N|entrezgene/locuslink:5530(identity)	intact:EBI-16439789(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RqM4Q9x8EiLx7CyoF2Rvjl5RddM9606	rogid:kYtl+Yk39rbcDp5vIjH8WLsZysU9606	rigid:TBMBRaQOIBs3sHBRkxKucLjJI8U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P597-2	uniprotkb:I6L9F6	intact:EBI-11033402|ensembl:ENSP00000466067	intact:EBI-10178578|intact:EBI-21999896	psi-mi:q6p597-2(display_long)|uniprotkb:KLC3(gene name)|psi-mi:KLC3(display_short)|uniprotkb:KLC2(gene name synonym)|uniprotkb:KLC2-like(gene name synonym)|uniprotkb:KLC2L(gene name synonym)|uniprotkb:kinesin light chain 2(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471874	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1643885(isoform-parent)|uniprotkb:Q6P597-2(isoform-parent)|ensembl:ENSG00000104892(gene)|ensembl:ENST00000585434(transcript)|entrezgene/locuslink:147700(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431586(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zVaRhvX9+4Aehqcmowox73QTJIM9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:A6QyR1rBN8hJrbSre9es50TL0H8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HD9	intact:EBI-16472255	intact:EBI-3916242|ensembl:ENSP00000255082	-	psi-mi:acy3_human(display_long)|uniprotkb:ACY3(gene name)|psi-mi:ACY3(display_short)|uniprotkb:Aspartoacylase-2(gene name synonym)|uniprotkb:ASPA2(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)	psi-mi:"ccsb isoform id: pmm2_2"(display_short)|psi-mi:EBI-16472255(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472258	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542389.1|ensembl:ENSG00000132744(gene)|ensembl:ENST00000255082(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q96HD9|reactome:R-HSA-5423646|go:"GO:0005829"(cytosol)|entrezgene/locuslink:91703(identity)	entrezgene/locuslink:5373(identity)	intact:EBI-16433187(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Zjs7m7GTDeoVuV1/ggtGOu1LRhM9606	rogid:0YDh3c3stuQYjWrXuET8c1cw22E9606	rigid:u/mZ+BNuVWxcL4y4dvFNAZolHFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P60201	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8653150|uniprotkb:P06905|uniprotkb:P04400|intact:MINT-8164000|uniprotkb:Q502Y1|uniprotkb:Q6FHZ6|ensembl:ENSP00000481006|ensembl:ENSP00000484450	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:mypr_human(display_long)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)|uniprotkb:Lipophilin(gene name synonym)|uniprotkb:PLP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472239	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_001291933.1|refseq:NP_955772.1|refseq:NP_000524.3|refseq:NP_001122306.1|ensembl:ENSG00000123560(gene)|ensembl:ENST00000612423(transcript)|ensembl:ENST00000621218(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60201|rcsb pdb:2XPG|entrezgene/locuslink:5354(identity)	intact:EBI-16438810(see-also)	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	comment:mint	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k9606	rigid:iwOcglLOmsndgtDROLLCVL52mmo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60201	uniprotkb:Q16849-3	intact:EBI-8653150|uniprotkb:P06905|uniprotkb:P04400|intact:MINT-8164000|uniprotkb:Q502Y1|uniprotkb:Q6FHZ6|ensembl:ENSP00000481006|ensembl:ENSP00000484450	intact:EBI-10200782|ensembl:ENSP00000392598	psi-mi:mypr_human(display_long)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)|uniprotkb:Lipophilin(gene name synonym)|uniprotkb:PLP(gene name synonym)	psi-mi:q16849-3(display_long)|uniprotkb:ICA3(gene name synonym)|uniprotkb:ICA512(gene name synonym)|uniprotkb:Islet cell antigen 512(gene name synonym)|uniprotkb:Islet cell autoantigen 3(gene name synonym)|uniprotkb:PTP IA-2(gene name synonym)|uniprotkb:PTPRN(gene name)|psi-mi:PTPRN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472220	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291933.1|refseq:NP_955772.1|refseq:NP_000524.3|refseq:NP_001122306.1|ensembl:ENSG00000123560(gene)|ensembl:ENST00000612423(transcript)|ensembl:ENST00000621218(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60201|rcsb pdb:2XPG|entrezgene/locuslink:5354(identity)	intact:EBI-728153(isoform-parent)|ensembl:ENSG00000054356(gene)|ensembl:ENST00000423636(transcript)|uniprotkb:Q16849-3(isoform-parent)|entrezgene/locuslink:5798(identity)	intact:EBI-16434953(see-also)	comment:mint	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k9606	rogid:i147CXtVMOlCBDl3Wto2zw6GSPU9606	rigid:5se/Z0tdMjX2p6qCjvM39i7JpqI	true	-	sufficient binding region:299-889	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P2K3-2	uniprotkb:Q96EK2	intact:EBI-1504830|ensembl:ENSP00000355973	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:q9p2k3-2(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472203	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117625(gene)|ensembl:ENST00000367006(transcript)|intact:EBI-743428(isoform-parent)|uniprotkb:Q9P2K3-2(isoform-parent)|entrezgene/locuslink:55758(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16440174(see-also)|intact:EBI-16440184(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RU9KkQB+JnxYVfG5IlAeNKnVFjw9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:tmtF2t8tQ5EsOCjtO44Y/bx6pJY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q96EK2	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472186	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16437800(see-also)|intact:EBI-16437810(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:DOVGuKuwNdi0gREbZoVxrSYJppo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:Q96EK2-3	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16437793|ensembl:ENSP00000487086	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:q96ek2-3(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)|uniprotkb:3(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472170	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	ensembl:ENST00000629843(transcript)|ensembl:ENSG00000056487(gene)|intact:EBI-16472119(isoform-parent)|uniprotkb:Q96EK2-3(isoform-parent)|entrezgene/locuslink:112885(identity)	intact:EBI-16434037(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:9SKSd1jo6PtvaF/ASqHgPFhu8aA9606	rigid:j1oPjYc7jmKeaQKidkQQlq/2GZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:Q96EK2	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472154	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16434037(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:Uos2STIXhb3b4aMIQYQls3Uv5ns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NWT1	uniprotkb:Q04864-2	intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8	intact:EBI-10829018|ensembl:ENSP00000377989	psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym)	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472103	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2|entrezgene/locuslink:55003(identity)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	intact:EBI-16435768(see-also)	comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rigid:+iNGwo1wK5QcKqQ4zUPD6I63vj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NWT1	uniprotkb:P31323	intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8	intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9	psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym)	psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472087	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2|entrezgene/locuslink:55003(identity)	ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N|entrezgene/locuslink:5577(identity)	intact:EBI-16431733(see-also)	comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606	rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606	rigid:h4XXAW4XX4GP4DPWk7kg7yghHRA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q86SE8-2	uniprotkb:P06748	intact:EBI-12193061|ensembl:ENSP00000370941|ensembl:ENSP00000481018	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755	psi-mi:q86se8-2(display_long)|uniprotkb:NPM2(gene name)|psi-mi:NPM2(display_short)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472071	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6658150(isoform-parent)|ensembl:ENSG00000158806(gene)|ensembl:ENST00000381530(transcript)|ensembl:ENST00000615914(transcript)|uniprotkb:Q86SE8-2(isoform-parent)|entrezgene/locuslink:10361(identity)	refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|entrezgene/locuslink:4869(identity)	intact:EBI-16431830(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/shy9sQPj5fdrbQSf7adFExPv509606	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	rigid:Eu7F8xODXGCQodPaIdotgvqU9aU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15942	uniprotkb:P56597	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	intact:EBI-740667|ensembl:ENSP00000265191|uniprotkb:B2R5G7	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:ndk5_human(display_long)|uniprotkb:nm23-H5(gene name synonym)|uniprotkb:Testis-specific nm23 homolog(gene name synonym)|uniprotkb:Inhibitor of p53-induced apoptosis-beta(gene name synonym)|uniprotkb:NME5(gene name)|psi-mi:NME5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472055	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1|entrezgene/locuslink:7791(identity)	refseq:NP_003542.1|ensembl:ENSG00000112981(gene)|ensembl:ENST00000265191(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR007858(Dpy-30)|interpro:IPR012410(Nucleoside-diphosphate kinase-like NDK-H5)|interpro:IPR034907|interpro:IPR036850|entrezgene/locuslink:8382(identity)	intact:EBI-16434589(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rogid:flqa+tg4JH0cBA5svsCSdmuGYys9606	rigid:lSGJdFmVd3xO/S/6vPO3jtF/Jvo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P56597	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-740667|ensembl:ENSP00000265191|uniprotkb:B2R5G7	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ndk5_human(display_long)|uniprotkb:nm23-H5(gene name synonym)|uniprotkb:Testis-specific nm23 homolog(gene name synonym)|uniprotkb:Inhibitor of p53-induced apoptosis-beta(gene name synonym)|uniprotkb:NME5(gene name)|psi-mi:NME5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472039	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_003542.1|ensembl:ENSG00000112981(gene)|ensembl:ENST00000265191(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR007858(Dpy-30)|interpro:IPR012410(Nucleoside-diphosphate kinase-like NDK-H5)|interpro:IPR034907|interpro:IPR036850|entrezgene/locuslink:8382(identity)	intact:EBI-16430546(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:flqa+tg4JH0cBA5svsCSdmuGYys9606	rigid:GE1IIt+yVfHQh11pD8DxPa0imMc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:Q9NZ94-2	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16423037	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472023	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent)|entrezgene/locuslink:54413(identity)	intact:EBI-16431179(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:zJAbB1paiNIkvVmQQT638+rczN49606	rigid:v/e5UXz62BGKyIqA+6CxC44kTjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P07196	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472004	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16440868(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:/jMaClIPjc+ha5XXS/pnkXE3rKg	true	-	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:I6L9F6	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-10178578|intact:EBI-21999896	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471988	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16440694(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:bqt5fey0jbY+6v3HCfGp1oRV1NM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16439879	uniprotkb:I6L9F6	-	intact:EBI-10178578|intact:EBI-21999896	psi-mi:"ccsb orf id: 8359"(display_short)|psi-mi:EBI-16439879(display_long)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471972	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:80125(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16439881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:poddy6+Qr+z8s1U2xyFnXJ05O6Y9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:8QaA/MJgLnCNAFv2+GUWm1wL1rQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P07196	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471953	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16439839(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:40LNdlMQMqMBRSwO1sTKaSPtIJQ	true	-	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P07196	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471931	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16438528(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:gVbM/IrSNp1AIb2n/qpYN8tIadc	true	sufficient binding region:383-1002	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P07196	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471909	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16432766(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:FVfBArJib5IuVn0U1Lt/RjVHkA8	true	sufficient binding region:9-925	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:I6L9F6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-10178578|intact:EBI-21999896	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471890	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431902(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:v8+T373idqYQsdVrdh3nra4+znk	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P62140	uniprotkb:O60237-2	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769	intact:EBI-10700351|ensembl:ENSP00000349206	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:o60237-2(display_long)|uniprotkb:PPP1R12B(gene name)|psi-mi:PPP1R12B(display_short)|uniprotkb:MYPT2(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472274	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N|entrezgene/locuslink:5500(identity)	ensembl:ENSG00000077157(gene)|ensembl:ENST00000356764(transcript)|intact:EBI-2558026(isoform-parent)|uniprotkb:O60237-2(isoform-parent)|entrezgene/locuslink:4660(identity)	intact:EBI-16434212(see-also)	-	isoform-comment:Produced by alternative splicing of isoform 1. No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	rogid:vroZRva3UhIrZLt/UaNvIhLoZWI9606	rigid:uJwnf7n0u3j9E9KKWB24k9OT1Jk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:Q96PK6	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472535	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16438860(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:fa6T4f9JDRgzDWRZ/khZMqSSRMo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:Q96PK6	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472519	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16434788(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:3KhOScmBqaMU84aGSRt2Vsb7oNQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:Q96PK6	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472503	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16434788(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:3KhOScmBqaMU84aGSRt2Vsb7oNQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUI8	uniprotkb:Q96PK6	intact:EBI-2872414|ensembl:ENSP00000318804|uniprotkb:Q2MLY7|uniprotkb:A6NJF3|uniprotkb:B2R8C3|uniprotkb:Q9Y6M8|uniprotkb:Q9UNI3	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:crlf3_human(display_long)|uniprotkb:CRLF3(gene name)|psi-mi:CRLF3(display_short)|uniprotkb:CRLM9(gene name synonym)|uniprotkb:CREME9(gene name synonym)|uniprotkb:CYTOR4(gene name synonym)|uniprotkb:P48(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 9(gene name synonym)|uniprotkb:Cytokine receptor-related protein 4(gene name synonym)|uniprotkb:Type I cytokine receptor-like factor p48(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472487	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176390(gene)|ensembl:ENST00000324238(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q8IUI8|refseq:NP_057070.3|entrezgene/locuslink:51379(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16430857(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:iUxgX/ff546WqMhszXxotEhEZ3c9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:H5kn/JCSrCdjmf1C41W93OtKoyw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUI8	uniprotkb:Q96PK6	intact:EBI-2872414|ensembl:ENSP00000318804|uniprotkb:Q2MLY7|uniprotkb:A6NJF3|uniprotkb:B2R8C3|uniprotkb:Q9Y6M8|uniprotkb:Q9UNI3	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:crlf3_human(display_long)|uniprotkb:CRLF3(gene name)|psi-mi:CRLF3(display_short)|uniprotkb:CRLM9(gene name synonym)|uniprotkb:CREME9(gene name synonym)|uniprotkb:CYTOR4(gene name synonym)|uniprotkb:P48(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 9(gene name synonym)|uniprotkb:Cytokine receptor-related protein 4(gene name synonym)|uniprotkb:Type I cytokine receptor-like factor p48(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472468	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176390(gene)|ensembl:ENST00000324238(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q8IUI8|refseq:NP_057070.3|entrezgene/locuslink:51379(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16430857(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iUxgX/ff546WqMhszXxotEhEZ3c9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:H5kn/JCSrCdjmf1C41W93OtKoyw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P05783	uniprotkb:Q9H939-2	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	intact:EBI-16472446|ensembl:ENSP00000468622	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:q9h939-2(display_long)|uniprotkb:PSTPIP2(gene name)|psi-mi:PSTPIP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472452	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N|entrezgene/locuslink:3875(identity)	ensembl:ENSG00000152229(gene)|ensembl:ENST00000589328(transcript)|intact:EBI-2609610(isoform-parent)|entrezgene/locuslink:9050(identity)	intact:EBI-16437711(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:RH1ReONZZRaeyckEt4RrJM7+Y6o9606	rigid:Z6T8ysweiEL3Fm5Rve8vetolld0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NTZ6	uniprotkb:P55345-4	intact:EBI-310707|uniprotkb:E1P5R6|uniprotkb:B3KRU2|uniprotkb:O94865|uniprotkb:Q8N3B1|uniprotkb:Q9H196|ensembl:ENSP00000352668|ensembl:ENSP00000363217|ensembl:ENSP00000363228	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:rbm12_human(display_long)|uniprotkb:HRIHFB2091(orf name)|uniprotkb:RBM12(gene name)|psi-mi:RBM12(display_short)|uniprotkb:KIAA0765(gene name synonym)|uniprotkb:RNA-binding motif protein 12(gene name synonym)|uniprotkb:SH3/WW domain anchor protein in the nucleus(gene name synonym)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472426	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185767.1|refseq:NP_001185769.1|refseq:NP_006038.2|refseq:NP_690051.1|ensembl:ENSG00000244462(gene)|ensembl:ENST00000359646(transcript)|ensembl:ENST00000374104(transcript)|ensembl:ENST00000374114(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034591|interpro:IPR034594|interpro:IPR034854|interpro:IPR034855|interpro:IPR034856|interpro:IPR035979|mint:Q9NTZ6|rcsb pdb:1WEL|rcsb pdb:2CPY|rcsb pdb:2DNN|rcsb pdb:2EK1|rcsb pdb:2EK6|entrezgene/locuslink:10137(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16437870(see-also)|intact:EBI-16437880(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Hcz7OUumWYuRnRNMjwFYUZBquVo9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:XgfZ/RRHPs7PoKp4qJMnC8ihfRY	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYN7	uniprotkb:P55345-4	intact:EBI-9089622|uniprotkb:Q5JXM8|uniprotkb:B7ZM09|uniprotkb:B2RXE5|uniprotkb:Q96ST5|uniprotkb:A2RUF4|ensembl:ENSP00000364346	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:zn341_human(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472407	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269862.1|refseq:NP_001269864.1|refseq:NP_116208.3|ensembl:ENSG00000131061(gene)|ensembl:ENST00000375200(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:84905(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16436358(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dEc17LamYWGrumF7ngc3Ayq4Q5E9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:oI6V8T9YE+aB+BUPjd/6KuACB4o	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYN7-2	uniprotkb:P55345-4	intact:EBI-16435478|ensembl:ENSP00000344308	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:q9byn7-2(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472388	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9089622(isoform-parent)|uniprotkb:Q9BYN7-2(isoform-parent)|ensembl:ENSG00000131061(gene)|ensembl:ENST00000342427(transcript)|entrezgene/locuslink:84905(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16435483(see-also)	isoform-comment:Gene prediction based on EST data.	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7vGJ+B6pyJ7Sog6LMmkaucXK7wI9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:YWgJMZcF6cB9o7e4GjZbzfphqgk	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	intact:EBI-16429374	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	-	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:"ccsb isoform id: prmt2_3"(display_short)|psi-mi:EBI-16429374(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472372	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	entrezgene/locuslink:3275(identity)	intact:EBI-16432622(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:OAAEKxGVtSlipjL4kONluFkiFFg9606	rigid:EtjRioy0w8WnVMUnPX01HgGZl5w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	uniprotkb:P55345-4	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472353	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16432622(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:O/0EvqF3PUmC9iQkzv6Bal0w+KM	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:P55345-4	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472334	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16429376(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:7b1WLlb2BvwvxA2JxNzrUQ9dI5I	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NSC5	intact:EBI-16472306	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	-	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"ccsb isoform id: prcc_2"(display_short)|psi-mi:EBI-16472306(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472309	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	entrezgene/locuslink:5546(identity)	intact:EBI-16438346(see-also)|intact:EBI-16438362(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:j9XRhH4ZEG79gSUCXnZokfMSv6E9606	rigid:0a5vrJ7qgMSW3cO+ihYPmNYiChY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:Q9Y252	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472771	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16437375(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:z4HqwWorXLwNu5gG2mw/NVyf/nU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P15884-3	uniprotkb:Q9Y252	intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472755	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436891(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:sG1I2ULJ6yENOLVLKQQpgkE9jic	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:Q9Y252	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472736	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436693(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:3uSAK59lF8WFNAzRmUQ/fBz4584	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43865	uniprotkb:Q9Y252	intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472720	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|entrezgene/locuslink:10768(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436468(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:PgrpiW1OCByu9NHS6FKoylD/I04	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q9Y252	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472704	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16432268(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:vxetvP2lyRMxdj6+r1ZcYeYMfSQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:Q9Y252	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472688	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16431645(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:1q8DgnV/tWtOKqV3mV+Dt8o+ZlE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:Q9Y252	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472672	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16431267(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:uSCHHG1cINwFT94V5/XhfGR9HXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:Q9Y252	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472653	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16430073(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:ovtR6kTbGzC+XWCuMyhRoRmPbzs	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16472634	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: rnf40_2"(display_short)|psi-mi:EBI-16472634(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472637	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:9810(identity)	intact:EBI-16439693(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:c3Cz6BGjD9iUCGN9Dqytq3QCQZQ9606	rigid:fXEnWosXfBN6dNWtN7/WekbqMiA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435576	uniprotkb:Q13671-2	-	intact:EBI-366034	psi-mi:"ccsb orf id: 53744"(display_short)|psi-mi:EBI-16435576(display_long)	psi-mi:q13671-2(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras inhibitor JC99(gene name synonym)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472618	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:140258(identity)	intact:EBI-366017(rin1_human)|entrezgene/locuslink:9610(identity)	intact:EBI-16435578(see-also)	-	isoform-comment:Shows reduced ability to bind to Ras and 14-3-3 proteins.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z0z+FcvFPqhBOHUsErdmi55IjpY9606	rogid:6g4wEXS1EKGBUMTrLAbbjPWsmZw9606	rigid:SU2IKHXFIaFeGS7yExue9rQWOxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435576	uniprotkb:Q13671	-	intact:EBI-366017|uniprotkb:O15010|uniprotkb:Q00427|uniprotkb:Q96CC8|ensembl:ENSP00000310406	psi-mi:"ccsb orf id: 53744"(display_short)|psi-mi:EBI-16435576(display_long)	psi-mi:rin1_human(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)|uniprotkb:Ras inhibitor JC99(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472602	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:140258(identity)	ensembl:ENSG00000174791(gene)|ensembl:ENST00000311320(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR036860|interpro:IPR037191|reactome:R-HSA-8876198|refseq:NP_004283.2|dip:DIP-117N|entrezgene/locuslink:9610(identity)	intact:EBI-16435578(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z0z+FcvFPqhBOHUsErdmi55IjpY9606	rogid:oj/ZbyM0Oqe0wDMlFbJHCtGzMwA9606	rigid:5MT0e4/X6I+9DYJieCkkvGjPJLU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	intact:EBI-16435574	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	-	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"ccsb isoform id: rin1_3"(display_short)|psi-mi:EBI-16435574(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472586	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	entrezgene/locuslink:9610(identity)	intact:EBI-16430576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:RW4Tn3lN56PIlLIZX5QTF7MoqSI9606	rigid:F0WfAz0iEC65wWmO6Z5NFCMkoRo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:Q13671-2	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-366034	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:q13671-2(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras inhibitor JC99(gene name synonym)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472570	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	intact:EBI-366017(rin1_human)|entrezgene/locuslink:9610(identity)	intact:EBI-16430576(see-also)	-	isoform-comment:Shows reduced ability to bind to Ras and 14-3-3 proteins.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:6g4wEXS1EKGBUMTrLAbbjPWsmZw9606	rigid:G7+Vl1dIbtY5woNwEVB3hDbghUY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:P52756	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472551	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N|entrezgene/locuslink:10181(identity)	intact:EBI-16431419(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606	rigid:Z4fe4FjpH6sV3b5q4MwUIAn8ibM	true	-	sufficient binding region:1-546	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:Q9Y252	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472834	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16438081(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:+1ryNgVk4q6063M6hCWnP0D29iU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:P23297	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473636	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247|entrezgene/locuslink:6271(identity)	intact:EBI-16435790(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rigid:uoTkRbs7ghXmE55qKOGNhCpzmuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z4M5	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16436147	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473617	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16440776(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:jh27oDnUQKxs0Vy9E9v4HAMHGaI	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P28702	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473598	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16440776(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:pvjQ5rxty4G2+HiWcuNGK4zwLJM	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:A0A0S2Z4M5	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-16436147	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473582	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16440246(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:FPIzT2OQ0XZynyzI+Z6sVnMz41I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:P28702	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473566	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16440246(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:TDnp1Dh/4VhZE0wtAoxbgXMSrb0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28702	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473545	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16438564(see-also)|intact:EBI-16438576(see-also)|intact:EBI-16438588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:Spwo90i0Ld+LLwwP0aq/5kexDUg	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	intact:EBI-16429002	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	-	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473526	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:SWzNpDZAfZVLb+X0gEtmIZJuNiQ	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	uniprotkb:A0A0S2Z4M5	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	intact:EBI-16436147	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473507	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:E3+0nhwqTZfRp7+KTbyTGkYkGs0	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	uniprotkb:P28702	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473488	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:nLqJGLGUZLBB7TIqEA4y84A5WBc	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	intact:EBI-16429002	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	-	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473472	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ZDB/qV1GOGb9d+JzT3ELg3BneZg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z4M5	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16436147	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473456	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:ut+BYEf5zg2MUBg+9+6JiZE6zsE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:P28702	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473440	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:D8Nto/SRm+viLYuc46jpPDZmq1A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05BL1	uniprotkb:P28702	intact:EBI-11952721|intact:EBI-12700013	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q05bl1_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473423	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|entrezgene/locuslink:7159(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16436408(see-also)|intact:EBI-16436418(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LA1UvPUs8vUyy7hDTxjj8DevaY89606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:nRoiusv6Em8hw9MlOBP0Z8uhb0E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96RI1-1	intact:EBI-16429002	intact:EBI-12417284|ensembl:ENSP00000376712|ensembl:ENSP00000496908	-	psi-mi:q96ri1-1(display_long)|uniprotkb:NR1H4(gene name)|psi-mi:NR1H4(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:FXR(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:HRR1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:RIP14(gene name synonym)|uniprotkb:FXRalpha1(isoform synonym)|uniprotkb:"FXRalpha1(+)"(isoform synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473406	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1250177(isoform-parent)|uniprotkb:Q96RI1-1(isoform-parent)|ensembl:ENSG00000012504(gene)|ensembl:ENST00000392986(transcript)|ensembl:ENST00000648861(transcript)|entrezgene/locuslink:9971(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16436328(see-also)|intact:EBI-16436338(see-also)	isoform-comment:Produced by alternative promoter usage.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xpym/8iahj3FgUKjQK3nt2XJZVI9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ecEh8cm1qV5iC9MPFjh2twRJz3s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96RI1-1	uniprotkb:A0A0S2Z4M5	intact:EBI-12417284|ensembl:ENSP00000376712|ensembl:ENSP00000496908	intact:EBI-16436147	psi-mi:q96ri1-1(display_long)|uniprotkb:NR1H4(gene name)|psi-mi:NR1H4(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:FXR(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:HRR1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:RIP14(gene name synonym)|uniprotkb:FXRalpha1(isoform synonym)|uniprotkb:"FXRalpha1(+)"(isoform synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473389	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1250177(isoform-parent)|uniprotkb:Q96RI1-1(isoform-parent)|ensembl:ENSG00000012504(gene)|ensembl:ENST00000392986(transcript)|ensembl:ENST00000648861(transcript)|entrezgene/locuslink:9971(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16436328(see-also)|intact:EBI-16436338(see-also)	isoform-comment:Produced by alternative promoter usage.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xpym/8iahj3FgUKjQK3nt2XJZVI9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:Ak/Z1is5XBeKdEbgm2u+MxnL9T4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:P28702	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473371	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16436137(see-also)|intact:EBI-16436162(see-also)|intact:EBI-16436172(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:4wWlT9MpE6l6Alp+lV9d8wZ0VTw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	intact:EBI-16429002	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	-	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473355	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ps4+jCqwt8yRLmrACxwQ/gL9BTA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:A0A0S2Z4M5	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-16436147	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473339	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:s68nk+FBO2Y8ApqAtE08fYGBfNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:P28702	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473323	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:DsdsCLGE5OF2EhbnASThoaDjZB8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10276	intact:EBI-16429002	intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649	-	psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473306	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|entrezgene/locuslink:5914(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16434599(see-also)|intact:EBI-16434609(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:4kDCKtuLkf0wlVGM7fEYPAz7XSo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	intact:EBI-16429002	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	-	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473290	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:W2N8aPS3ik2EnT7ofcHvXTjVB7w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:A0A0S2Z4M5	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16436147	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473274	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:dkX0qokVhXCSmRLytr7irJxVpbY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P28702	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473258	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:/8DA4bc0MGrP1CpV9e/rTTBNITQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:A0A0S2Z4M5	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-16436147	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473242	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16433157(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:kI0whDKhu286XxONvjj+s6UKf6Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:P28702	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473226	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16433157(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:uBeZTkrOBp4shfWG8lV/0Ae7ZIs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z4M5	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16436147	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473209	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16433077(see-also)|intact:EBI-16433127(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:uAIlDYWyMrVKSYPWod9ATFWEIoQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P28702	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473192	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16433077(see-also)|intact:EBI-16433127(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:1tjfvuf55zFLgyCA1QSmVJ5YATI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	intact:EBI-16429002	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	-	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473176	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:Mv9GtBXuxejzdxuHcQp/C1q+U5k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:A0A0S2Z4M5	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-16436147	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473160	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:6kN7yvvmOiOtfe/Pa78YVhghKy4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P28702	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473144	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:iIJP/lkfE26iqBS8D0xGMnSZTNc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P28702	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473127	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16432168(see-also)|intact:EBI-16432178(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:plQD6GfJY3DxjVu8Coe02DnYpGg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	intact:EBI-16429002	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473108	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:iFK2kTzkm8fWn4N9OtvK9Pn2vG4	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4M5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16436147	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473089	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:OuNrcSL5T8+ryouUcMai+OWWHiE	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28702	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473070	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:Spwo90i0Ld+LLwwP0aq/5kexDUg	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10276-2	intact:EBI-16429002	intact:EBI-10197061|ensembl:ENSP00000377643	-	psi-mi:p10276-2(display_long)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473054	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-413374(isoform-parent)|ensembl:ENSG00000131759(gene)|ensembl:ENST00000394081(transcript)|uniprotkb:P10276-2(isoform-parent)|entrezgene/locuslink:5914(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N94HvF3F7xteoDkwcGx1TS7x+Qw9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:j4DuGIoAMgKiX61Eo9ke8ZAoWDQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	intact:EBI-16429002	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	-	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473038	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:gNqubSiOBgV1QPdW910/QhgiGF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	uniprotkb:A0A0S2Z4M5	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-16436147	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473022	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:l9rbsZs0kLHD1/BwsWRmNlmQAiI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	uniprotkb:P28702	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473006	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:PEjzYiZ3QgzCdr39ib9C57V7OsU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13133-3	intact:EBI-16429002	intact:EBI-11952806|ensembl:ENSP00000378793	-	psi-mi:q13133-3(display_long)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472989	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-781356(isoform-parent)|uniprotkb:Q13133-3(isoform-parent)|ensembl:ENSG00000025434(gene)|ensembl:ENST00000395397(transcript)|entrezgene/locuslink:10062(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16430261(see-also)|intact:EBI-16430271(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:goIAjD2Xf+TWijq46YePOb3130s9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:jXEenehpAij/qbGbo4xfZXbKnjM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10826-2	intact:EBI-16429002	intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912	-	psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472972	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|entrezgene/locuslink:5915(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16429684(see-also)|intact:EBI-16429694(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ZPEwmvIE0yArGfssE3AU5UCQH74	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10826-2	uniprotkb:A0A0S2Z4M5	intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912	intact:EBI-16436147	psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472955	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|entrezgene/locuslink:5915(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429684(see-also)|intact:EBI-16429694(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:pIqpOpn9mMe94H9jcCbFdkD0F/w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	intact:EBI-16429002	intact:EBI-10172526|ensembl:ENSP00000413976	-	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472936	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:l90SdhBXVORV0RX+oyPrIx0vICM	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z4M5	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16436147	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472917	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:U/bGqc8FqDTsJzm6AGe9yy5Bxqc	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P28702	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472898	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:uk8sqgJ7JAIRxXYfMYMiXx2IhUQ	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:A0A0S2Z4M5	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-16436147	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472882	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429004(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:Mkn2AgMP1/SKgiO2ffOJmB56j40	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:P28702	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472866	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16429004(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:8mbSyibJVly/ouHGbeptZwsiyVU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9Y252	intact:EBI-16439278	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472850	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16439703(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:zLRXOfUDZX9OmdtNFfhnoRB8c18	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B96	uniprotkb:P04271	intact:EBI-7055862|ensembl:ENSP00000233047|ensembl:ENSP00000261388|ensembl:ENSP00000460687|ensembl:ENSP00000492164|ensembl:ENSP00000492501|ensembl:ENSP00000491056|intact:MINT-8163962|intact:MINT-8201794|uniprotkb:A6NMA9|uniprotkb:O00323|uniprotkb:B4DEC1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:ldaf1_human(display_long)|uniprotkb:LDAF1(gene name)|psi-mi:LDAF1(display_short)|uniprotkb:Promethin(gene name synonym)|uniprotkb:TMEM159(gene name synonym)|uniprotkb:Transmembrane protein 159(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473668	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288698.1|refseq:NP_001288700.1|refseq:NP_001288702.1|refseq:NP_001288703.1|refseq:NP_001288704.1|ensembl:ENSG00000011638(gene)|ensembl:ENSG00000283997(gene)|ensembl:ENST00000233047(transcript)|ensembl:ENST00000261388(transcript)|ensembl:ENST00000572599(transcript)|ensembl:ENST00000638934(transcript)|ensembl:ENST00000640188(transcript)|ensembl:ENST00000640514(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR029709|mint:Q96B96|refseq:NP_065155.3|refseq:XP_005255496.1|refseq:XP_006721129.1|entrezgene/locuslink:57146(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16433197(see-also)	comment:mint	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qDMjn8OVxY8eRUFJTc8hxD3Tk0c9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:0BTil7T0QqJyCIlGs0FUbTjzOgg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WW34-2	uniprotkb:P04271	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473652	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16432656(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:vo0sxxLMrrw40b4ACaH0jA5OcP0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:A0A0S2Z4E5	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-16432288	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474588	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:HJRl3l20mQQ31+TuorpRv/6xzDs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P29034	uniprotkb:A8MRB1	intact:EBI-752230|uniprotkb:O00266|uniprotkb:Q3KRB9|uniprotkb:Q5RHS8|uniprotkb:Q9BU83|ensembl:ENSP00000357697|ensembl:ENSP00000357698|ensembl:ENSP00000357699|ensembl:ENSP00000473260	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s10a2_human(display_long)|uniprotkb:S100 calcium-binding protein A2(gene name synonym)|uniprotkb:CAN19(gene name synonym)|uniprotkb:S100A2(gene name)|psi-mi:S100A2(display_short)|uniprotkb:S100L(gene name synonym)|uniprotkb:Protein S-100L(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473714	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005969.1|ensembl:ENSG00000196754(gene)|ensembl:ENST00000368708(transcript)|ensembl:ENST00000368709(transcript)|ensembl:ENST00000368710(transcript)|ensembl:ENST00000487430(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:P29034|rcsb pdb:2RGI|rcsb pdb:4DUQ|entrezgene/locuslink:6273(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16434379(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QcJWxtqLrbXj++33nNw9nHxj5oE9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:CqF/wkpANeHcXuhJVWYTy+nPryM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4E5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16432288	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474553	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16438600(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:6tEx4D9xL4/iiA5+4O3Ca+I1epM	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4F2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16429215	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474534	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16438600(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:1sbTnPwVeX2VeHR7zNDxytGnjMI	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:Q15561	-	intact:EBI-747736|ensembl:ENSP00000352926|uniprotkb:Q92883|uniprotkb:Q96BK2|uniprotkb:Q6MZR9|uniprotkb:H0Y308|uniprotkb:Q8NEV5	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:tead4_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)|uniprotkb:RTEF1(gene name synonym)|uniprotkb:TCF13L1(gene name synonym)|uniprotkb:TEF3(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:Transcription factor RTEF-1(gene name synonym)|uniprotkb:Transcription factor 13-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474514	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_003204.2|refseq:NP_958849.1|refseq:NP_958851.1|ensembl:ENSG00000197905(gene)|ensembl:ENST00000359864(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0035329"(hippo signaling)|go:"GO:0048568"(embryonic organ development)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:5GZB|rcsb pdb:5NO6|rcsb pdb:5OAQ|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6Q2X|rcsb pdb:6Q36|rcsb pdb:6SEN|reactome:R-HSA-2032785|rcsb pdb:6SEO|reactome:R-HSA-8951671|dip:DIP-61626N|entrezgene/locuslink:7004(identity)	intact:EBI-16437079(see-also)|intact:EBI-16437089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:DSb1zdydvEWM1RQ8uRwOJ7dX6AE9606	rigid:dyzmVQ3eU6SSsv0eMArtihg57FQ	true	-	sufficient binding region:74-434	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q15561	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-747736|ensembl:ENSP00000352926|uniprotkb:Q92883|uniprotkb:Q96BK2|uniprotkb:Q6MZR9|uniprotkb:H0Y308|uniprotkb:Q8NEV5	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:tead4_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)|uniprotkb:RTEF1(gene name synonym)|uniprotkb:TCF13L1(gene name synonym)|uniprotkb:TEF3(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:Transcription factor RTEF-1(gene name synonym)|uniprotkb:Transcription factor 13-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474494	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_003204.2|refseq:NP_958849.1|refseq:NP_958851.1|ensembl:ENSG00000197905(gene)|ensembl:ENST00000359864(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0035329"(hippo signaling)|go:"GO:0048568"(embryonic organ development)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:5GZB|rcsb pdb:5NO6|rcsb pdb:5OAQ|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6Q2X|rcsb pdb:6Q36|rcsb pdb:6SEN|reactome:R-HSA-2032785|rcsb pdb:6SEO|reactome:R-HSA-8951671|dip:DIP-61626N|entrezgene/locuslink:7004(identity)	intact:EBI-16435184(see-also)|intact:EBI-16435194(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:DSb1zdydvEWM1RQ8uRwOJ7dX6AE9606	rigid:arzo3ovF4ZwlmJBGKatYntV/TPs	true	-	sufficient binding region:74-434	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q59EK9-3	uniprotkb:A0A0S2Z4E5	intact:EBI-11957366|ensembl:ENSP00000225441	intact:EBI-16432288	psi-mi:q59ek9-3(display_long)|uniprotkb:RUNDC3A(gene name)|psi-mi:RUNDC3A(display_short)|uniprotkb:RAP2IP(gene name synonym)|uniprotkb:RPIP8(gene name synonym)|uniprotkb:Rap2-interacting protein 8(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474477	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108309(gene)|ensembl:ENST00000225441(transcript)|intact:EBI-747225(isoform-parent)|uniprotkb:Q59EK9-3(isoform-parent)|entrezgene/locuslink:10900(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16434527(see-also)|intact:EBI-16434539(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KM1XwGq52oeYft6Ywt8DsEdrsE49606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:4/giA48KAix4up6LAK6oX0dtUgk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IX15-3	uniprotkb:A0A0S2Z4E5	intact:EBI-10172004|ensembl:ENSP00000453979	intact:EBI-16432288	psi-mi:q8ix15-3(display_long)|uniprotkb:HOMEZ(gene name)|psi-mi:HOMEZ(display_short)|uniprotkb:Homeodomain leucine zipper-containing factor(gene name synonym)|uniprotkb:KIAA1443(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474458	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10742083(isoform-parent)|ensembl:ENSG00000215271(gene)|ensembl:ENST00000561013(transcript)|entrezgene/locuslink:57594(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16431540(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M8cGyd/inWQJqBNkUtEfmFNDDoA9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:eKQykkdjSsLLfWGtNxicRaV5lGo	true	sufficient binding region:27-552	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IX15-3	uniprotkb:A0A0S2Z4F2	intact:EBI-10172004|ensembl:ENSP00000453979	intact:EBI-16429215	psi-mi:q8ix15-3(display_long)|uniprotkb:HOMEZ(gene name)|psi-mi:HOMEZ(display_short)|uniprotkb:Homeodomain leucine zipper-containing factor(gene name synonym)|uniprotkb:KIAA1443(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474439	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10742083(isoform-parent)|ensembl:ENSG00000215271(gene)|ensembl:ENST00000561013(transcript)|entrezgene/locuslink:57594(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16431540(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M8cGyd/inWQJqBNkUtEfmFNDDoA9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:pGudwovWrjP0v1qaFgPYK8Kb1Ow	true	sufficient binding region:27-552	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:A0A0S2Z4E5	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-16432288	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474423	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430897(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:gYZF+lJvCRZjD1jk6qSSa7jZohY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:A0A0S2Z4F2	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-16429215	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474407	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430897(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:QVeTek1yNAzu2uahVTzex68k6Z4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:A0A0S2Z4E5	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-16432288	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474391	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430833(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:7Z/E9Nq+ZayfyPhe5vxk1vAg6W0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:A0A0S2Z4F2	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-16429215	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474375	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430833(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:TbloL6KVdY/cHhkYjicUjHSenuA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z4E5	-	intact:EBI-16432288	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474359	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430660(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:9m0vty/XdtQQKCxHj6gXzJKDVo4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z4F2	-	intact:EBI-16429215	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474343	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430660(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:jIdyl8cDQiZUY/G8ce12XqoScYk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z4E5	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16432288	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474327	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429947(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:qZQcuFygKbrzwDrWf6Dr1ZjvNFg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z4F2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16429215	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474311	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429947(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:b+SLibk/KTH66WNZnAyrfMmG/FA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z4E5	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16432288	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474294	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429203(see-also)|intact:EBI-16429217(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:d9rkrGrlqzsnkxCFhth2gGO0ZjE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:A0A0S2Z511	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-16474234	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474278	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16440044(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:ZoDhhl3GA5scdWNTnqp2m4dMHh0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:A0A0S2Z511	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16474234	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474262	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16439154(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:VKpBZfOOkbuSd8E6N4VBzyDxkbo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:A0A0S2Z511	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-16474234	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474246	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16432904(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:+EPk1Rz5UUzWkWGu6DZ4pqJ1A3w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:O00506-2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474172|ensembl:ENSP00000384444|ensembl:ENSP00000385541	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:o00506-2(display_long)|uniprotkb:Ste20-like kinase(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474215	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensembl:ENSG00000115694(gene)|ensembl:ENST00000405585(transcript)|ensembl:ENST00000405883(transcript)|intact:EBI-618295(isoform-parent)|entrezgene/locuslink:10494(identity)	intact:EBI-16431986(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:pwb8CAj6GQUnAHoo11bcPTR91IM9606	rigid:ada10D0vs6KmRZXt48GiUbcuSgM	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z503	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474153	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z503_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474196	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|entrezgene/locuslink:10494(identity)	intact:EBI-16431986(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tvI0cMppiIA52VqBLfnbNVmtGDk9606	rigid:s9BgdiT+YbugS65tUAcUxG9k1SM	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z503	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16474153	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z503_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474156	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|entrezgene/locuslink:10494(identity)	intact:EBI-16429937(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:tvI0cMppiIA52VqBLfnbNVmtGDk9606	rigid:ZB5ecBUUkZlld1C59/9+pEsgfxo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:O00506-2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16474172|ensembl:ENSP00000384444|ensembl:ENSP00000385541	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:o00506-2(display_long)|uniprotkb:Ste20-like kinase(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474180	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	ensembl:ENSG00000115694(gene)|ensembl:ENST00000405585(transcript)|ensembl:ENST00000405883(transcript)|intact:EBI-618295(isoform-parent)|entrezgene/locuslink:10494(identity)	intact:EBI-16429937(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:pwb8CAj6GQUnAHoo11bcPTR91IM9606	rigid:ynmpe821OEJySWD5QvOQH0f+bRw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q00013	uniprotkb:O75494	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474137	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361|entrezgene/locuslink:4354(identity)	refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1|entrezgene/locuslink:10772(identity)	intact:EBI-16433466(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606	rigid:rhiG6mhrXwlZbpF+HggFdX+Op2w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:Q53HV7-2	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-12275818|ensembl:ENSP00000243112|ensembl:ENSP00000421139|ensembl:ENSP00000421206|ensembl:ENSP00000423629	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:q53hv7-2(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474121	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	uniprotkb:Q53HV7-2(isoform-parent)|intact:EBI-749970(isoform-parent)|ensembl:ENSG00000123415(gene)|ensembl:ENST00000243112(transcript)|ensembl:ENST00000506595(transcript)|ensembl:ENST00000513838(transcript)|ensembl:ENST00000514685(transcript)|uniprotkb:Q53HV7(isoform-parent)|entrezgene/locuslink:23583(identity)	intact:EBI-16429664(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:m1cNtgPOvISKrGW4fehXpyQZRrw9606	rigid:SamHd3CHkfhSOqvtd8AZg9OYfaI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJX2	uniprotkb:Q53HV7-2	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	intact:EBI-12275818|ensembl:ENSP00000243112|ensembl:ENSP00000421139|ensembl:ENSP00000421206|ensembl:ENSP00000423629	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:q53hv7-2(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474102	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	uniprotkb:Q53HV7-2(isoform-parent)|intact:EBI-749970(isoform-parent)|ensembl:ENSG00000123415(gene)|ensembl:ENST00000243112(transcript)|ensembl:ENST00000506595(transcript)|ensembl:ENST00000513838(transcript)|ensembl:ENST00000514685(transcript)|uniprotkb:Q53HV7(isoform-parent)|entrezgene/locuslink:23583(identity)	intact:EBI-16429123(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:m1cNtgPOvISKrGW4fehXpyQZRrw9606	rigid:M2FVQbV3Ne8s8FbTB0r5hIJMwA4	true	sufficient binding region:7-597	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z3I3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16474045	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z3i3_human(display_long)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474086	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395|entrezgene/locuslink:1468(identity)	intact:EBI-16435174(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:FisbtsXIhWmngIvwcYU9gLLuTwM9606	rigid:n0I1bK9llI+wGGq40vTV9PRROQY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q9UBX3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474070	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|entrezgene/locuslink:1468(identity)	intact:EBI-16435174(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	rigid:Ld3t/lXV+Iil7z3Vet3JzPctoiM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:A0A0S2Z3I3	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-16474045	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:a0a0s2z3i3_human(display_long)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474054	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395|entrezgene/locuslink:1468(identity)	intact:EBI-16431297(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:FisbtsXIhWmngIvwcYU9gLLuTwM9606	rigid:3B170fxEebUlWjYENXFBKQCd3Dc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:Q9UBX3	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474029	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|entrezgene/locuslink:1468(identity)	intact:EBI-16431297(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	rigid:6ys05+5fCYjheBxSzCOSNXp612U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	intact:EBI-16473978	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	-	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474013	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16440034(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:9/k/y6HP4Vf4qZWs+v9PrgSSDkc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	intact:EBI-16473978	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	-	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473997	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16437285(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:t022CSVW7dkPY0AY5mixkNGVF6k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	intact:EBI-16473978	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	-	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473981	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16432894(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:97WVEXwq2wi+PFFoa+IQ9csMnP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:A0A0S2Z333	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-16473949	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:a0a0s2z333_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473962	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0045916"(negative regulation of complement activation)|interpro:IPR015553(Protease inhibitor I4, serpin C1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR036186|entrezgene/locuslink:710(identity)	intact:EBI-16434943(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:1jC9AiVsX+YrqhHm6Iui/gFSeMQ9606	rigid:CTrhJ+M02FMnL7B3BmJVoMUFp/o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:P05155	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407|ensembl:ENSP00000504807	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473933	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	refseq:NP_000053.2|refseq:NP_001027466.1|dip:DIP-45635N|ensembl:ENSG00000149131(gene)|ensembl:ENST00000278407(transcript)|ensembl:ENST00000676670(transcript)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008015"(blood circulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015553(Protease inhibitor I4, serpin C1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:1M6Q|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606|entrezgene/locuslink:710(identity)	intact:EBI-16434943(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606	rigid:cUaBrTAao5GFuvhyMqx42LdOvHc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:A0A0S2Z4S8	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-16473914	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:a0a0s2z4s8_human(display_long)|uniprotkb:SEC22C(gene name)|psi-mi:SEC22C(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473917	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0005737"(cytoplasm)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|interpro:IPR011012(Longin-like)|interpro:IPR043546|entrezgene/locuslink:9117(identity)	intact:EBI-16432558(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:qtheyub4kGDZY6MAK9tpWjCdiHI9606	rigid:7l4spnIGyrZKKf4i9pFc89XAA+A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:A0A0S2Z4S0	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-16473895	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:a0a0s2z4s0_human(display_long)|uniprotkb:SEC22C(gene name)|psi-mi:SEC22C(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473898	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR043546|entrezgene/locuslink:9117(identity)	intact:EBI-16432558(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:8Jep7RaAGYriguPiEBULdHp3FkI9606	rigid:l2tQuoo8uhCb+kZsjX9ufHBMuAo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:D3DPN2	-	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473879	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16437069(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:ZkDxy8rz4lLud216K9KZJHn86SQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:D3DPN2	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473863	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16436585(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid://5f+bH76hol0GiGyo5Pjun0TLs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR9	uniprotkb:D3DPN2	intact:EBI-14065470|ensembl:ENSP00000377583|ensembl:ENSP00000458927|uniprotkb:Q495J2	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra24_human(display_long)|uniprotkb:KRTAP2-4(gene name)|psi-mi:KRTAP2-4(display_short)|uniprotkb:High sulfur keratin-associated protein 2.4(gene name synonym)|uniprotkb:KAP2.4(gene name synonym)|uniprotkb:KRTAP2.4(gene name synonym)|uniprotkb:Keratin-associated protein 2.4(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473847	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000213417(gene)|ensembl:ENSG00000263091(gene)|ensembl:ENST00000394015(transcript)|ensembl:ENST00000572903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_001158724.1|refseq:NP_149440.1|entrezgene/locuslink:85294(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16436488(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QSitkYej4+CJRhx3YsYNjKB15FY9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:9qfsPxReeUG1q3JdK3qDxRgyO10	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:D3DPN2	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473831	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16431287(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:aoxfE18ZyWzdELK/CelrH783Itw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WZ60	intact:EBI-16473794	intact:EBI-6426464|ensembl:ENSP00000341342|uniprotkb:D3DNS8|uniprotkb:Q8N5I1|uniprotkb:B2RB31|uniprotkb:Q8N892	-	psi-mi:klhl6_human(display_long)|uniprotkb:KLHL6(gene name)|psi-mi:KLHL6(display_short)	psi-mi:"ccsb isoform id: sbds_3"(display_short)|psi-mi:EBI-16473794(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473797	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172578(gene)|ensembl:ENST00000341319(transcript)|go:"GO:0002467"(germinal center formation)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR029851|refseq:NP_569713.2|entrezgene/locuslink:89857(identity)	entrezgene/locuslink:51119(identity)	intact:EBI-16440728(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3HSrMq8OrULpGu1i53jA+tFs+xA9606	rogid:KXnpJUs1hkhqKmAUGHAutje9X2A9606	rigid:v0m4QtLF9Vq7zpk993tm+08F0h8	true	sufficient binding region:12-621	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P04271	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473778	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16439144(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:wUErtfCHTW8i4XaTH+TuzLyXNL8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23297	uniprotkb:A8MRB1	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473762	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247|entrezgene/locuslink:6271(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16437425(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:2lNJRKvHaeoQVkyr61lU9xqBm1k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:P04271	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473746	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16437275(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:gqly5ZxlKoVphTaFsHZQerGoj/A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P04271	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473730	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16434838(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:bEKr9JIJIFO+ykQKqUdThHicWK8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04271	uniprotkb:A8MRB1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473698	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16433849(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:kvj3OmJXQiVuC0X4nkYTb0DenjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:A0A0S2Z4F2	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-16429215	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474572	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:A7n5cU4PnLzy30cEMoC9cuvtOvc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HA47-2	uniprotkb:Q9HA47-2	intact:EBI-16434682|ensembl:ENSP00000361282	intact:EBI-16434682|ensembl:ENSP00000361282	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474809	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	intact:EBI-16434688(see-also)	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rigid:tiBFlDEcc4567EuaagBAdO4XKf4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	intact:EBI-16474742	-	-	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474793	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16430672(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:+T8K3qdBKP8Eg18p9TvxlXtWn+s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16474742	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474777	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16429720(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:6DpVutyXiUillZFxkuEI22mCI/c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	intact:EBI-16474742	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	-	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474761	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16429067(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:5wdlBkDr2x3nWF6FFonvXYzFYv4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	intact:EBI-16474742	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	-	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474745	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16428962(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:b8HvF5MMUT1Iup9uvxri9+PASH0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z611	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16474723	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z611_human(display_long)|uniprotkb:TMEM67(gene name)|psi-mi:TMEM67(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474726	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0060271"(cilium assembly)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019170|entrezgene/locuslink:91147(identity)	intact:EBI-16431191(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:T+MPKb/Ekjn5/2LbWj6xoHUd8+I9606	rigid:WnNq68CO5tOnH7UP9KhrsNq/uzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:Q5HYA8	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-11334880|uniprotkb:B3KRU5|uniprotkb:Q8IZ06|uniprotkb:Q7Z5T8|uniprotkb:G5E9H2|uniprotkb:Q3ZCX3|uniprotkb:B3KT47|ensembl:ENSP00000314488|ensembl:ENSP00000389998	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:mks3_human(display_long)|uniprotkb:TMEM67(gene name)|psi-mi:TMEM67(display_short)|uniprotkb:MKS3(gene name synonym)|uniprotkb:Meckel syndrome type 3 protein(gene name synonym)|uniprotkb:Transmembrane protein 67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474704	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005813"(centrosome)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031005"(filamin binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019170|reactome:R-HSA-5620912|ensembl:ENSG00000164953(gene)|ensembl:ENST00000323130(transcript)|ensembl:ENST00000453321(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|entrezgene/locuslink:91147(identity)	intact:EBI-16431191(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:4YrnhWM1UaytyidG1L/ikUBHZlY9606	rigid:Ev8k2ZpADf6AEO2kT6jy2JGU+/E	true	-	sufficient binding region:11-995	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HH9	intact:EBI-16474685	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	-	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"ccsb isoform id: tmem43_2"(display_short)|psi-mi:EBI-16474685(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474688	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	entrezgene/locuslink:79188(identity)	intact:EBI-16433789(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:uxAcxqfUYh0DNraC4u9Jyz52/wg9606	rigid:lS0vtbmEF6jvcmGkCl8c76LN3Ec	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z6S1	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474646	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z6s1_human(display_long)|uniprotkb:TEX9(gene name)|psi-mi:TEX9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474665	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:374618(identity)	intact:EBI-16438614(see-also)|intact:EBI-16438626(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:6fh/qjSn0/Yy9eZsqEm3hGVB8gY9606	rigid:q+FO9YM9b7P/jvVHKERhC+bXkVs	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:A0A0S2Z6S1	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-16474646	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:a0a0s2z6s1_human(display_long)|uniprotkb:TEX9(gene name)|psi-mi:TEX9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474649	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	entrezgene/locuslink:374618(identity)	intact:EBI-16431659(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:6fh/qjSn0/Yy9eZsqEm3hGVB8gY9606	rigid:0hXrLxWRcA4cTPV332DiYyhDGFw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:A0A0S2Z4E5	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-16432288	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474629	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440888(see-also)|intact:EBI-16440900(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:Z45z5aT8PwryAC9bG0bFDtR/WJY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:P54577	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-1048893|uniprotkb:O43276|uniprotkb:Q53EN1|uniprotkb:B3KWK4|uniprotkb:D3DPQ4|ensembl:ENSP00000362576	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:syyc_human(display_long)|uniprotkb:YARS1(gene name)|psi-mi:YARS1(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YARS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475111	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_003671.1|ensembl:ENSG00000134684(gene)|ensembl:ENST00000373477(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005153"(interleukin-8 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006437"(tyrosyl-tRNA aminoacylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:1N3L|rcsb pdb:1NTG|rcsb pdb:1Q11|rcsb pdb:4Q93|rcsb pdb:4QBT|rcsb pdb:5THH|rcsb pdb:5THL|reactome:R-HSA-379716|dip:DIP-50415N|entrezgene/locuslink:8565(identity)	intact:EBI-16435802(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:y/0Qs8iOgW5w5LVLWnCvowVpEu89606	rigid:pXubpguM35D63KpLdhNImXjQDbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:A0A0S2Z555	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-16475060	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:a0a0s2z555_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475095	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	interpro:IPR036045|interpro:IPR043154|entrezgene/locuslink:26276(identity)	intact:EBI-16438372(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:ihNrx9Ir+4ZSDi9Uolbp1fXCV8E9606	rigid:mUBSeXoE3g/zv8CpWHTZXpIo7q4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:A0A0S2Z589	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-16475041	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:a0a0s2z589_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475079	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	entrezgene/locuslink:26276(identity)	intact:EBI-16438372(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:YB3/q1I8N7Ggx8pqaUE76hdAbPg9606	rigid:MThsbLDIv7OQwe22IZnHqe5Zgi4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H9C1	uniprotkb:A0A0S2Z555	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	intact:EBI-16475060	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:a0a0s2z555_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475063	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1|entrezgene/locuslink:63894(identity)	interpro:IPR036045|interpro:IPR043154|entrezgene/locuslink:26276(identity)	intact:EBI-16433017(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rogid:ihNrx9Ir+4ZSDi9Uolbp1fXCV8E9606	rigid:KCIooJumEuwOCsZDypZEOZ+Of6E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H9C1	uniprotkb:A0A0S2Z589	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	intact:EBI-16475041	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:a0a0s2z589_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475044	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1|entrezgene/locuslink:63894(identity)	entrezgene/locuslink:26276(identity)	intact:EBI-16433017(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rogid:YB3/q1I8N7Ggx8pqaUE76hdAbPg9606	rigid:GAYzdWonLhs0Zj6OwhbTSDFQhH4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5H5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16475012	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5h5_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475022	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0000813"(ESCRT I complex)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|interpro:IPR038358|refseq:XP_005272381.1|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017899|interpro:IPR017898|interpro:IPR037202|interpro:IPR037206|entrezgene/locuslink:51160(identity)	intact:EBI-16438638(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:I1oHVgmyOif0+MUSGRncDDdOMDI9606	rigid:qmVhq0+Kp2TVlvSCADIOYt1ixzA	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z698	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16474860	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474991	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16440788(see-also)|intact:EBI-16440802(see-also)|intact:EBI-16440816(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:vN1ipA4gQFDraWrnX06T1nviL8Q	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z639	intact:EBI-16439278	intact:EBI-16440814	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474975	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:DHHYoNcOb37ulcBGTeAl8G53sfE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z698	intact:EBI-16439278	intact:EBI-16474860	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474959	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:5smZGw0i6+TQaD6i/7SDUpGfajI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z6U5	intact:EBI-16439278	intact:EBI-16432858	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z6u5_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474943	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0044206"(UMP salvage)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|refseq:XP_005246416.1|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:VyzKKO5ec+Y8bdAeaJtLyApjOak9606	rigid:gqQDw5h56p3GTIZV2Ba9yJ5QYBQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95045-2	uniprotkb:A0A0S2Z639	intact:EBI-11528386|ensembl:ENSP00000474090	intact:EBI-16440814	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474923	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16432844(see-also)|intact:EBI-16432860(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:pp8sXtmY1T4sW/eDS2wew/+BpBQ	true	sufficient binding region:58-374	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95045-2	uniprotkb:A0A0S2Z698	intact:EBI-11528386|ensembl:ENSP00000474090	intact:EBI-16474860	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474903	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16432844(see-also)|intact:EBI-16432860(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:Lh/fLgss+AWGNNNNfvnAj2LugJg	true	sufficient binding region:58-374	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z639	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16440814	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474887	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:TIivXsRUj8ALRNOIb/WB0GYTb84	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z698	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16474860	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474871	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:vN1ipA4gQFDraWrnX06T1nviL8Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z6U5	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16432858	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z6u5_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474844	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0044206"(UMP salvage)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|refseq:XP_005246416.1|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:VyzKKO5ec+Y8bdAeaJtLyApjOak9606	rigid:oC4nKqUXADb9RQFLJQzVRVVcvrA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HA47-2	uniprotkb:Q9HA47	intact:EBI-16434682|ensembl:ENSP00000361282	intact:EBI-717582|uniprotkb:Q5JT12|uniprotkb:Q6IA74|uniprotkb:Q5JT09|uniprotkb:Q5JT13|uniprotkb:Q96BJ0|uniprotkb:Q5JT10|ensembl:ENSP00000361289	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:uck1_human(display_long)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474825	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	refseq:NP_001129426.1|refseq:NP_113620.1|refseq:NP_001305448.1|refseq:NP_001248379.1|refseq:NP_001248380.1|ensembl:ENSG00000130717(gene)|ensembl:ENST00000372215(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029920|rcsb pdb:2JEO|rcsb pdb:2UVQ|reactome:R-HSA-73614|entrezgene/locuslink:83549(identity)	intact:EBI-16434688(see-also)	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rogid:SPTYxIH9wm04Tx4T1A+EV7HZ4Yk9606	rigid:mU8ztoEQaxor3Y/WJQBUe1bVML4	true	-	sufficient binding region:1-232	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P0C7X2	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475501	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:13DNDdpoLi9/tB8ON/n2pUOPSyw	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BQY4	uniprotkb:A0A0S2Z564	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-16475127	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:a0a0s2z564_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475134	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:27033(identity)	intact:EBI-16432666(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:dXjoGOAoXzVBI3tXnuT+/JmnJIM9606	rigid:aS1+FX83Ip8ZX9aWsk02EQem6/I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P0C7X2	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475469	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429227(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:E4vr9aj5p7CCi/53FLdmZPadu4g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z6P0	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16429989	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475453	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:iCF5+8S6UpoHwjr/vLJ9+G2sEJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P0C7X2	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475437	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:d2EC12ai7pLHxgPaxeCvObrf+IQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:A0A0S2Z6P0	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-16429989	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475421	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:efCBE+x1hLNa4AQxrv3yLIz/l4s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:P0C7X2	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475405	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:0LyYoJdbIGqZ6fgrBwqqpyElgfI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:A0A0S2Z6P0	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-16429989	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475389	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jRHI67I5lOmWoOXVBatytEwalGs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:P0C7X2	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475373	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:eCuRq+1r0BQmzAhW61hLbDO29CM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P17040-4	uniprotkb:Q969J2	intact:EBI-16440054|ensembl:ENSP00000362512	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:p17040-4(display_long)|uniprotkb:Zinc finger protein 31(gene name synonym)|uniprotkb:Zinc finger protein 360(gene name synonym)|uniprotkb:Zinc finger protein KOX29(gene name synonym)|uniprotkb:ZSCAN20(gene name)|psi-mi:ZSCAN20(display_short)|uniprotkb:KOX29(gene name synonym)|uniprotkb:ZNF31(gene name synonym)|uniprotkb:ZNF360(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475357	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000121903(gene)|ensembl:ENST00000373413(transcript)|intact:EBI-745838(isoform-parent)|entrezgene/locuslink:7579(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16440062(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qHCR8fgETOY4paUgFW7PPM/aGT89606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:yktMyOELVtXF00ECaS9/pFP2Tj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15151	uniprotkb:Q969J2	intact:EBI-398437|uniprotkb:Q32SL2|uniprotkb:Q6GS18|uniprotkb:Q8IV83|intact:EBI-3932059|uniprotkb:Q2M2Y2|intact:EBI-28988565|ensembl:ENSP00000356150	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:mdm4_human(display_long)|uniprotkb:MDM4(gene name)|psi-mi:MDM4(display_short)|uniprotkb:MDMX(gene name synonym)|uniprotkb:p53-binding protein Mdm4(gene name synonym)|uniprotkb:Mdm2-like p53-binding protein(gene name synonym)|uniprotkb:Protein Mdmx(gene name synonym)|uniprotkb:Double minute 4 protein(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475341	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002384.2|refseq:NP_001191101.1|refseq:NP_001191100.1|ensembl:ENSP00000356150|ensembl:ENST00000367183|ensembl:ENSP00000356151|ensembl:ENST00000454264|ensembl:ENSP00000396840|refseq:NP_001265445.1|refseq:NP_001265446.1|refseq:NP_001265447.1|refseq:NP_001265448.1|dip:DIP-24199N|reactome:R-HSA-69541|reactome:R-HSA-6804760|ensembl:ENSG00000198625(gene)|ensembl:ENST00000367182(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003170"(heart valve development)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015458(MDM4/MDMX protein)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR036443|interpro:IPR036885|mint:O15151|rcsb pdb:2CR8|rcsb pdb:2MWY|rcsb pdb:2N06|rcsb pdb:2N0U|rcsb pdb:2N0W|rcsb pdb:2N14|rcsb pdb:2VJE|rcsb pdb:2VJF|rcsb pdb:2VYR|rcsb pdb:3DAB|rcsb pdb:3EQY|rcsb pdb:3FDO|rcsb pdb:3FE7|rcsb pdb:3FEA|rcsb pdb:3JZO|rcsb pdb:3JZP|rcsb pdb:3JZQ|rcsb pdb:3LBJ|rcsb pdb:3MQR|rcsb pdb:3U15|rcsb pdb:4RXZ|rcsb pdb:5MNJ|rcsb pdb:5UML|rcsb pdb:5VK1|rcsb pdb:6Q9Q|rcsb pdb:6Q9S|rcsb pdb:6Q9U|rcsb pdb:6Q9W|rcsb pdb:6Q9Y|rcsb pdb:7C3Q|rcsb pdb:7C3Y|rcsb pdb:7C44|rcsb pdb:7EL4|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-5689880|reactome:R-HSA-6804756|reactome:R-HSA-6804757|entrezgene/locuslink:4194(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16431554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zAL03wG+qlPT5folNjx1ZUJhx/A9606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:1D5tAwqqnvalY143E54lkEONOCE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P088	uniprotkb:Q969J2	intact:EBI-10196963|ensembl:ENSP00000438048	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:q6p088_human(display_long)|uniprotkb:ZNF483(gene name)|psi-mi:ZNF483(display_short)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475325	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016869828.1|ensembl:ENSG00000173258(gene)|ensembl:ENST00000355824(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR036051|interpro:IPR038269|entrezgene/locuslink:158399(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16431096(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SXAiqzd6g4YN0PLaLlPAbSnBTMU9606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:CjDEwT5mY3l5+Tln8Xtmx0gBdmA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z6H0	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16428984	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z6h0_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475309	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	interpro:IPR041367|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR043560|entrezgene/locuslink:84619(identity)	intact:EBI-16436214(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ezg+DgS3ra4uCIomSOVb3WD4oxU9606	rigid:5Z0yNONIUHLT6bUuHxBeQPDQRz4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:Q8N5A5-2	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-10183064|ensembl:ENSP00000348242|ensembl:ENSP00000358984|ensembl:ENSP00000391176	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:q8n5a5-2(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475293	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	intact:EBI-3439227(isoform-parent)|ensembl:ENSG00000197114(gene)|ensembl:ENST00000355969(transcript)|ensembl:ENST00000369967(transcript)|ensembl:ENST00000448100(transcript)|uniprotkb:Q8N5A5-2(isoform-parent)|entrezgene/locuslink:84619(identity)	intact:EBI-16435224(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:DoBoYNv5QTlYVrPNdQvRKrcyeqA9606	rigid:2q8uLKQ1+8gLn/nJa6JM6jdeycc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16475183	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475275	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16439747(see-also)|intact:EBI-16439759(see-also)|intact:EBI-16439769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:6eFBKinLIBak/o2vAtYUyuKrDNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	intact:EBI-16475183	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	-	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475259	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:oIgQrd9USLLOff06/8w/7mXXRVw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5E1	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16439757	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5e1_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475243	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:kd2aWGkvURF0tE0/nLpaz7LijXc9606	rigid:vhpu/2MbKHxQh4pQzVQ0H7e2NW0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5J5	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16475219	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5j5_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475227	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:p//ETQJAR8nI0LAzxAcx/GOpaJA9606	rigid:zweV7vJSqTb6rapt8bHCXadtp2U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q9H0M4-4	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16429732|ensembl:ENSP00000419187	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:q9h0m4-4(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475203	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	ensembl:ENST00000490721(transcript)|ensembl:ENSG00000078487(gene)|intact:EBI-8659823(isoform-parent)|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:pfDCuBoXLZLhuU/JiaUzpFUAmbU9606	rigid:r8+ua2OWvjHqCjqpkcjmBnzU5WU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16475183	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475186	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16429737(see-also)|intact:EBI-16429749(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:tjq25KMBU4bcScfnO2ItbNfnIZs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:A0A0S2Z5E1	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16439757	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:a0a0s2z5e1_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475166	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16429737(see-also)|intact:EBI-16429749(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:kd2aWGkvURF0tE0/nLpaz7LijXc9606	rigid:IbsqEGGpNVP7kelfNACKtxgAS+M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:A0A0S2Z564	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16475127	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:a0a0s2z564_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475150	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:27033(identity)	intact:EBI-16433779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:dXjoGOAoXzVBI3tXnuT+/JmnJIM9606	rigid:TCjVm5G4ehiG2PWbM1wIXS89oFc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z6P0	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16429989	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475485	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429227(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:N/C6x8xI+eqpBTTZ0Rq/d14UIhQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-16429989	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476070	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432394(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:rgDgdU4CKWdBP7IZcD3lve7pp0Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z6P0	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16429989	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475541	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ke0tNxslAf5HvHAmhu86mWKedok	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:A0A0S2Z6P0	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-16429989	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476038	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432324(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:flMUDK2T89keoZpeHqsABAH6ECA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P0C7X2	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476022	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432324(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:VGjafZth0tz0qhwBEq3uyhHTUec	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P0C7X2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476005	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432188(see-also)|intact:EBI-16432198(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:zt+Cd+Sd/TKTSyCodArGTl6Zato	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NT76	uniprotkb:A0A0S2Z6P0	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-16429989	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475989	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1|entrezgene/locuslink:79618(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432078(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:fl+dfcxwO4iyM+RwRA197GEvfW0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NT76	uniprotkb:P0C7X2	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475973	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1|entrezgene/locuslink:79618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432078(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:o8mReh9jULlmd8ynRSpt5OF4fEw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P0C7X2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475953	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432034(see-also)|intact:EBI-16432046(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Q6vQ35jSx5hOsBoj1ho5wRdaZqk	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-3	uniprotkb:A0A0S2Z6P0	intact:EBI-16431743|ensembl:ENSP00000451368	intact:EBI-16429989	psi-mi:q9h257-3(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475937	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000489932(transcript)|uniprotkb:Q9H257-3(isoform-parent)|entrezgene/locuslink:64170(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431768(see-also)	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8ZrBhVHfPbIFpll5feiFDiUdyYs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:i3vd8GNtaQve3GdAnon6OMv1ICw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-3	uniprotkb:P0C7X2	intact:EBI-16431743|ensembl:ENSP00000451368	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9h257-3(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475921	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000489932(transcript)|uniprotkb:Q9H257-3(isoform-parent)|entrezgene/locuslink:64170(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431768(see-also)	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8ZrBhVHfPbIFpll5feiFDiUdyYs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:KchmooM8U5tY8LsmQlNnKxtKLd8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:P0C7X2	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475904	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431669(see-also)|intact:EBI-16431679(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:4/SghshfxNAL4xsGLS03RMul0iU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:A0A0S2Z6P0	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-16429989	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475888	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431277(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:zLYaqQvfwYpaWaekWC/G3CIPeC4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:P0C7X2	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475872	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431277(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:2nqrQQJspQh0TL/GPftu1VW6xz0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:P0C7X2	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475856	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064|entrezgene/locuslink:7681(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431211(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:8E9WSXM0Q/gy1GONMK86aT6bsP0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P25788	uniprotkb:A0A0S2Z6P0	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	intact:EBI-16429989	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475840	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:hzjmqAWpB+oZzYFunTdyg/Cr8ck	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P25788	uniprotkb:P0C7X2	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475824	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:wGdY4FpDC58/zsuuw2uQ5u+NOic	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:P0C7X2	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475808	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431032(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:uDGhrqK40w/fBOobCh1W8yjbGXQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:P0C7X2	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475775	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430803(see-also)|intact:EBI-16430813(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:l+HZW6vSyq/CXOgwcXjw+4B1BQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:P0C7X2	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475792	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430845(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:T0BvUp+TsPvdfaIv3PAgDcArVV4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475759	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:4wbmY9haTpGLGiF65PdGFILWjhE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475743	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:cITdTpjhYrWVbcYmNy3ApoXa1jc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475727	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430492(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:CGSWlgBvvWrDD/MkcjPa5hdEKCY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475711	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430492(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:k9xBdvcTuWhfoCM/f+IqfCtwVSI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99081-3	uniprotkb:A0A0S2Z5X4	intact:EBI-11952764|ensembl:ENSP00000331057|ensembl:ENSP00000388940	intact:EBI-16429014	psi-mi:q99081-3(display_long)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:c(isoform synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475695	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-722877(isoform-parent)|uniprotkb:Q99081-3(isoform-parent)|ensembl:ENSG00000140262(gene)|ensembl:ENST00000333725(transcript)|ensembl:ENST00000438423(transcript)|entrezgene/locuslink:6938(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16430405(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Sz84TChPfDPpa01k4znWJvWbQWU9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:Ah2u0nterhlZNw+r4ahYcydVd1g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99081-3	uniprotkb:P0C7X2	intact:EBI-11952764|ensembl:ENSP00000331057|ensembl:ENSP00000388940	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q99081-3(display_long)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:c(isoform synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475679	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-722877(isoform-parent)|uniprotkb:Q99081-3(isoform-parent)|ensembl:ENSG00000140262(gene)|ensembl:ENST00000333725(transcript)|ensembl:ENST00000438423(transcript)|entrezgene/locuslink:6938(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430405(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Sz84TChPfDPpa01k4znWJvWbQWU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:I0iaNPLLKKRTgC5rBx2xBiX/3wA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:A0A0S2Z6P0	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-16429989	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475663	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430341(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:hEtwBrRwBgMRdH4hHxnZ03CUt7Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P0C7X2	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475647	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430341(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:HOx8CJU2bEk4EvY4N4ZuA2BB5jg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BVG8-5	uniprotkb:A0A0S2Z6P0	intact:EBI-14069005|ensembl:ENSP00000396399|ensembl:ENSP00000454659|ensembl:ENSP00000456239	intact:EBI-16429989	psi-mi:q9bvg8-5(display_long)|uniprotkb:KIFC3(gene name)|psi-mi:KIFC3(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475631	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2125614(isoform-parent)|uniprotkb:Q9BVG8-5(isoform-parent)|ensembl:ENSG00000140859(gene)|ensembl:ENST00000421376(transcript)|ensembl:ENST00000465878(transcript)|ensembl:ENST00000562903(transcript)|entrezgene/locuslink:3801(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430207(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0+/OISIWq43SLdciB0TI/JqsEUo9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:EugJlqVDotRHFcg2W7wEUSpjr5s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BVG8-5	uniprotkb:P0C7X2	intact:EBI-14069005|ensembl:ENSP00000396399|ensembl:ENSP00000454659|ensembl:ENSP00000456239	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9bvg8-5(display_long)|uniprotkb:KIFC3(gene name)|psi-mi:KIFC3(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475615	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2125614(isoform-parent)|uniprotkb:Q9BVG8-5(isoform-parent)|ensembl:ENSG00000140859(gene)|ensembl:ENST00000421376(transcript)|ensembl:ENST00000465878(transcript)|ensembl:ENST00000562903(transcript)|entrezgene/locuslink:3801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430207(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0+/OISIWq43SLdciB0TI/JqsEUo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:R00a+plrL+SLBzXjTjNF/pLhTJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:A0A0S2Z6P0	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-16429989	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475596	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430097(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XVnx74tl2VYyKZ4yPL1knPdITfU	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:P0C7X2	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475577	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430097(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Xb4tmt4nlMWTvdG8dalXJU7xY3o	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P0C7X2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475560	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429991(see-also)|intact:EBI-16430001(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:zt+Cd+Sd/TKTSyCodArGTl6Zato	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P0C7X2	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476054	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432394(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:LkFVSjeY6uLv/OYA04FCAWk0Zr8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:P0C7X2	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476118	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432476(see-also)|intact:EBI-16432486(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:ZTNcIGu+3T43kPeJASd6dLO18Lw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:A0A0S2Z6P0	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-16429989	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476102	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432446(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:YWssy0Jqv+6UHsgD7n4hELdDUBg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P0C7X2	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476086	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432446(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:KTK4s8ioGirDukR27WnKAkc5urs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:P0C7X2	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476355	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:b3tDKzmIWmhnNFRD+K5pnYIOFmw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:A0A0S2Z6P0	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-16429989	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476339	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433496(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jRoX2n7Mbh2ndU1Pa9Reeg1h34k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:P0C7X2	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476323	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433496(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:5CCISQbZQ//OlFza0wPMKo39X8A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z5X4	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16429014	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476307	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16433373(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:QPWtG8mtDAMb8UTb+KXt33b2zis	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P0C7X2	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476291	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433373(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:A1ZgkSRFNjr4bIgAqc9yX3nYKHU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:P0C7X2	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476275	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433167(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:hK/IxWTd2IWCIiNHCyJWHHTSOE8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z6P0	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16429989	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476259	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433137(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ow8Wv+fHTFOxrjD/XHDj66D+v6g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P0C7X2	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476243	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433137(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:MAw+gpA0lm9atJBEEimpyKG5qy0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KQ7	uniprotkb:A0A0S2Z6P0	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-16429989	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476224	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|entrezgene/locuslink:10919(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432973(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:InmNGe5ecE4/MzcxWZdtX8Kk5BQ	true	sufficient binding region:210-1210	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KQ7	uniprotkb:P0C7X2	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476205	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|entrezgene/locuslink:10919(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432973(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3jPCjDToxPCKN6oju6XA5RLLuxw	true	sufficient binding region:210-1210	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:A0A0S2Z6P0	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-16429989	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476186	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432832(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:YKrZRPvBQPtzKXBx/HaiFIknZ2U	true	sufficient binding region:11-594	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P0C7X2	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476167	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432832(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:q/LHZYbjm8Nk2ZKixm3WNRbW13c	true	sufficient binding region:11-594	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8HWS3	uniprotkb:A0A0S2Z6P0	intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208	intact:EBI-16429989	psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476151	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432756(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:zucX9mNZ1DLFnMMhTONa4D4z424	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8HWS3	uniprotkb:P0C7X2	intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476135	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432756(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:nuxUn8iRe6JuWcR6omqlz7J4U5M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P0C7X2	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476784	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435972(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:qW1oJ40QhcW5KgpcASLmqoB7ZNY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P0C7X2	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476400	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433633(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:cIJG+vN56IGKvufmyqZB9RmhJQU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:A0A0S2Z6P0	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16429989	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476416	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433633(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XH3NHdAwFxuQPZudHw1lJZ2Jd/M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P0C7X2	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476432	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433971(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:vyxSQmZH8l1nomX53OAlZ8vo7Oo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A2RRN7	uniprotkb:P0C7X2	intact:EBI-10179719|intact:EBI-12002280|intact:EBI-12753183	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:a2rrn7_human(display_long)|uniprotkb:CADPS(gene name)|psi-mi:CADPS(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477112	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR033227|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|go:"GO:0015031"(protein transport)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0098793"(presynapse)|go:"GO:1990504"(dense core granule exocytosis)|entrezgene/locuslink:8618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16437185(see-also)|intact:EBI-16437195(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N5Akbv6I+Z6ng6fGGng679DVg9U9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3L6u/BQOBN01TD0uSXsVXD4To1I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477096	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16437099(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:tC1rxWIvqfufMI2CCOW3asbBtfA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477080	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16437099(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Rj51Sm51x1jb4F/OwhBCPjO7tf0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P15884-3	uniprotkb:P0C7X2	intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477063	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436901(see-also)|intact:EBI-16436911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:TuXBhajKajlEwZ0fAKz48OuXZF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60411	uniprotkb:A0A0S2Z6P0	intact:EBI-10172052|uniprotkb:A2RRG1|uniprotkb:Q70LJ1|uniprotkb:A6NIR9|ensembl:ENSP00000381009	intact:EBI-16429989	psi-mi:kr109_human(display_long)|uniprotkb:KRTAP10-9(gene name)|psi-mi:KRTAP10-9(display_short)|uniprotkb:High sulfur keratin-associated protein 10.9(gene name synonym)|uniprotkb:KAP10.9(gene name synonym)|uniprotkb:KAP18-9(gene name synonym)|uniprotkb:KRTAP10.9(gene name synonym)|uniprotkb:KRTAP18-9(gene name synonym)|uniprotkb:KRTAP18.9(gene name synonym)|uniprotkb:Keratin-associated protein 10.9(gene name synonym)|uniprotkb:Keratin-associated protein 18-9(gene name synonym)|uniprotkb:Keratin-associated protein 18.9(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477047	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_941963.2|ensembl:ENSG00000221837(gene)|ensembl:ENST00000397911(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_941965.2|entrezgene/locuslink:386676(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436841(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nh6MH4M6TUhmqNrV+Oj14IwKk389606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:txRtkDQ8Sh0q3cx5p85pywUnXc8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60411	uniprotkb:P0C7X2	intact:EBI-10172052|uniprotkb:A2RRG1|uniprotkb:Q70LJ1|uniprotkb:A6NIR9|ensembl:ENSP00000381009	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kr109_human(display_long)|uniprotkb:KRTAP10-9(gene name)|psi-mi:KRTAP10-9(display_short)|uniprotkb:High sulfur keratin-associated protein 10.9(gene name synonym)|uniprotkb:KAP10.9(gene name synonym)|uniprotkb:KAP18-9(gene name synonym)|uniprotkb:KRTAP10.9(gene name synonym)|uniprotkb:KRTAP18-9(gene name synonym)|uniprotkb:KRTAP18.9(gene name synonym)|uniprotkb:Keratin-associated protein 10.9(gene name synonym)|uniprotkb:Keratin-associated protein 18-9(gene name synonym)|uniprotkb:Keratin-associated protein 18.9(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477031	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_941963.2|ensembl:ENSG00000221837(gene)|ensembl:ENST00000397911(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_941965.2|entrezgene/locuslink:386676(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436841(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nh6MH4M6TUhmqNrV+Oj14IwKk389606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:eeu43XxUpcpxMrVS7hCrcf007uM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P59991	uniprotkb:A0A0S2Z6P0	intact:EBI-10176379|uniprotkb:Q0VAS4|uniprotkb:A6NIS1|uniprotkb:A6NMS9|ensembl:ENSP00000354001	intact:EBI-16429989	psi-mi:kr122_human(display_long)|uniprotkb:KRTAP12-2(gene name)|psi-mi:KRTAP12-2(display_short)|uniprotkb:High sulfur keratin-associated protein 12.2(gene name synonym)|uniprotkb:KAP12.2(gene name synonym)|uniprotkb:KRTAP12.2(gene name synonym)|uniprotkb:Keratin-associated protein 12.2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477015	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_859012.1|ensembl:ENSG00000221864(gene)|ensembl:ENST00000360770(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|entrezgene/locuslink:353323(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436757(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:No3kGE8TWTn4MyHaXXBiGmc5LIk9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:y84+U58Mka0QoBejo9AkkeuTB+c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P59991	uniprotkb:P0C7X2	intact:EBI-10176379|uniprotkb:Q0VAS4|uniprotkb:A6NIS1|uniprotkb:A6NMS9|ensembl:ENSP00000354001	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kr122_human(display_long)|uniprotkb:KRTAP12-2(gene name)|psi-mi:KRTAP12-2(display_short)|uniprotkb:High sulfur keratin-associated protein 12.2(gene name synonym)|uniprotkb:KAP12.2(gene name synonym)|uniprotkb:KRTAP12.2(gene name synonym)|uniprotkb:Keratin-associated protein 12.2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476999	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_859012.1|ensembl:ENSG00000221864(gene)|ensembl:ENST00000360770(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|entrezgene/locuslink:353323(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436757(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:No3kGE8TWTn4MyHaXXBiGmc5LIk9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:7aBfaFtYmsN3f4d+Vuf3Lbwi+NY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:A0A0S2Z6P0	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-16429989	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476980	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436705(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jXQO23obzinqUYhUBOAwC/gtENk	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:P0C7X2	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476961	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436705(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:9qsWCUZQggcDE5GSjc6Jr42XbmM	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:P0C7X2	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476944	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436625(see-also)|intact:EBI-16436635(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:wN8CXYYsHSn5nNZJiYKdUbfd5Hw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:A0A0S2Z6P0	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-16429989	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476928	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436595(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:ePjNApUmS5w/hVmBBaokNkT3mMs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:P0C7X2	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476912	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436595(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3ZlUWoa3t9ay5DCVia0zxqhcmWk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:A0A0S2Z6P0	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-16429989	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476896	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436458(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:FfE0QV0usCjiDfoltzZdBvHfs6I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:P0C7X2	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476880	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436458(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Kt7CK+ltILCt5uiP2wV9EUEd6Eg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3S9	uniprotkb:A0A0S2Z6P0	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	intact:EBI-16429989	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476864	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436368(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:IdzTEBf5+nD10VTZVl4gAXXQy/Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3S9	uniprotkb:P0C7X2	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476848	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436368(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:NrGsIS6oMvf2aYZLC7jt2dfq+3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476832	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436298(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:mh/NGgpgao9T98FXX6UkVbfhel0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:P0C7X2	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476816	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436224(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:SOBH7IjCC5Y3wO3BbsNut37uQ9s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-16429989	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476800	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435972(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XAFfqfxiU0tIgTccebE4AYcg2m8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:A0A0S2Z6P0	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-16429989	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476384	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:VsaqY3aJ9KVOei9PsSePvhAQD7M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:P0C7X2	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476768	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435942(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:nwBAtGil8HP8t+0mN+IGpRTyBB4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476752	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435360(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:s1z0l/6danZtuf0i7ju31YfUexI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476736	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435360(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:rrvFm9J4EO0cnnTkV/Hcd6j94eo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:P0C7X2	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476720	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:+PX85qwwZmmTrA2a+gl6dlMUOqo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z6P0	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16429989	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476704	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435204(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:h5z7rIqXNdf+bribtgzjbSQliqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P0C7X2	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476688	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435204(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:rmcgY77p9F5FpfsQ5m61pbbhtQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61457	uniprotkb:A0A0S2Z6P0	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	intact:EBI-16429989	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476672	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434965(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:GhdzrvjxQ8rgdat+QclPPnhwTZg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61457	uniprotkb:P0C7X2	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476656	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434965(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:K2alx7GmGgdoSQW3QINW5teW+bw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:P0C7X2	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476640	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434798(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:1IoMiuFRC9b7n4FJYsPSlBWI4Os	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z5X4	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16429014	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476624	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16434579(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:6EqiMiHgeiTW2hjizeeOqornido	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:P0C7X2	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476608	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434579(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:FcKoOUU3Hb8rKBvBGhuM85J4bK0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NQZ6	uniprotkb:P0C7X2	intact:EBI-747993|uniprotkb:Q5JTF9|uniprotkb:Q9H9C3|uniprotkb:Q9H9H7|uniprotkb:Q9ULQ4|uniprotkb:B2RDC2|uniprotkb:B4DED0|uniprotkb:E7EM74|uniprotkb:B3KVZ5|uniprotkb:G3V1L3|uniprotkb:Q53H73|ensembl:ENSP00000363972	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:zc4h2_human(display_long)|uniprotkb:ZC4H2(gene name)|psi-mi:ZC4H2(display_short)|uniprotkb:KIAA1166(gene name synonym)|uniprotkb:HCA127(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 127(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476592	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171503.1|refseq:NP_061154.1|refseq:NP_001230733.1|refseq:NP_001171504.1|ensembl:ENSG00000126970(gene)|ensembl:ENST00000374839(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR018482|interpro:IPR044069|entrezgene/locuslink:55906(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434453(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:lQr6Z1Cs3RuhckvFry86sAyycBE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:2qN6drLUEjFlAgq2Fpq3APaZqHw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:A0A0S2Z6P0	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-16429989	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476576	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434443(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:eLDSTWw0N2lP8Yu14kKBGu8cles	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P0C7X2	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476560	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434443(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:vyxSQmZH8l1nomX53OAlZ8vo7Oo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:A0A0S2Z6P0	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-16429989	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476544	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434327(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:2K/3rD3Eplvwqs+g+pTYt+RF4hM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P0C7X2	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476528	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434327(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:oOX8OE9qQ8E7HaXkJrl/zimTAvI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P209	uniprotkb:A0A0S2Z6P0	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	intact:EBI-16429989	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476512	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434170(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:16uA93uouFfVYDws8Qr4YPXbfKs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P209	uniprotkb:P0C7X2	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476496	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434170(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:1QtWoRNWUzLGcuL2k/sILgRyaUM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:A0A0S2Z6P0	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-16429989	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476480	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434160(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ydkc93ODUO3H1cXfizUyKtDyQDc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:P0C7X2	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476464	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434160(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:6WFNPDQhXctyR5/nAricutmgofc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:A0A0S2Z6P0	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-16429989	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476448	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433971(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:eLDSTWw0N2lP8Yu14kKBGu8cles	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:P0C7X2	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477129	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:NeA5Bhr8f7g12DW1wO7ZFWRhqoo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z6P0	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16429989	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477145	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:7l6zAgauzuru4ydPeS/6aR2ibTo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P0C7X2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477161	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438674(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Q6vQ35jSx5hOsBoj1ho5wRdaZqk	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P0C7X2	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477180	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:pTKXz4eljW6tWkORjUMcjh45XbE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:P0C7X2	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477225	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438870(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:dYkYWT4q876ZLYSXiTx6UWw/y0U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:A0A0S2Z6P0	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-16429989	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477241	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438870(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:fYS0vFFT6sY7eIA0xtMJWiVhTbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P0C7X2	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477257	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439859(see-also)|intact:EBI-16439869(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:368jHYgp+2WnbT2Vgm8V0kRse58	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16439879	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 8359"(display_short)|psi-mi:EBI-16439879(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477274	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:80125(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439913(see-also)|intact:EBI-16439923(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:poddy6+Qr+z8s1U2xyFnXJ05O6Y9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:SjA8oAebTiqkQOA72Zv4uE/G3Qw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-16429989	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477209	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:8PYvyU0aZ//Lc9FgVXGORn9LI0w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:P0C7X2	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477323	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440256(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:jRgMz45OsmRxhwuw0jwjsnCKgJk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:P0C7X2	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477291	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439984(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:WcECaDS6pZZZ8+Vb9HneFem3VFI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P0C7X2	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477339	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440378(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:R0V6KxExeohKy5kGOmnD7rgvHMo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:A0A0S2Z6P0	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-16429989	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477355	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16440378(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:P+kfyheVI4t6gP5Z0sGMikFjAzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:P0C7X2	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477371	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440614(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:i0IxYizsKcOrZmpc581iL27GK2c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:A0A0S2Z6P0	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-16429989	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477387	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16440614(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:xi6Kz7sJEQBF9vRcrmhn9aU4QHQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:P0C7X2	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477403	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:4QAt3KNBBXWuCCqRIrlbUHcsOCU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:A0A0S2Z6P0	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-16429989	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477307	intact-miscore:0.37	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16439984(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:my4AO1HKqtFHUmVaqCVNPLBoBIQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND76-3	uniprotkb:Q00536	intact:EBI-11615551|ensembl:ENSP00000265375|ensembl:ENSP00000363838	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	psi-mi:q8nd76-3(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym)	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mikolcevic et al. (2012)	imex:IM-25032|pubmed:22184064	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615543	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000265375(transcript)|ensembl:ENST00000374706(transcript)	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	intact:EBI-11615500(see-also)	-	-	figure legend:Fig. 1B|negative:The interaction does not occur under these experimental conditions.|comment:There was some evidence of a weak interaction but the authors appear to have regarded this as background|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293a)|taxid:9606(Homo sapiens)	-	2016/02/26	2016/02/26	rogid:ewRRPhM7GmaqFd/2ULUuzFHPAPw9606	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	rigid:ELM9C6YfCXPK2o+aTtd7+pQFN5Y	true	yellow fluorescent protein tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8ND76-3	uniprotkb:Q00536	intact:EBI-11615551|ensembl:ENSP00000265375|ensembl:ENSP00000363838	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	psi-mi:q8nd76-3(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym)	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mikolcevic et al. (2012)	imex:IM-25032|pubmed:22184064	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11620018	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000265375(transcript)|ensembl:ENST00000374706(transcript)	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	intact:EBI-11615466(see-also)	-	-	figure legend:Fig. 1B|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293a)|taxid:9606(Homo sapiens)	-	2016/02/26	2016/03/08	rogid:ewRRPhM7GmaqFd/2ULUuzFHPAPw9606	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	rigid:ELM9C6YfCXPK2o+aTtd7+pQFN5Y	true	yellow fluorescent protein tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00175-2	uniprotkb:O35739	intact:EBI-13642820|ensembl:ENSMUSP00000096584	intact:EBI-12591632	psi-mi:q00175-2(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 3(gene name synonym)|uniprotkb:Pgr(gene name)|psi-mi:Pgr(display_short)|uniprotkb:Nr3c3(gene name synonym)|uniprotkb:Pr(gene name synonym)|uniprotkb:PRA(isoform synonym)|uniprotkb:PR-A(isoform synonym)	psi-mi:klf9_mouse(display_long)|uniprotkb:Klf9(gene name)|psi-mi:Klf9(display_short)|uniprotkb:Bteb(gene name synonym)|uniprotkb:Bteb-1(gene name synonym)|uniprotkb:Bteb1(gene name synonym)|uniprotkb:Basic transcription element-binding protein 1(gene name synonym)|uniprotkb:GC-box-binding protein 1(gene name synonym)|uniprotkb:Transcription factor BTEB1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2003)	pubmed:12672823|imex:IM-25653	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13642814	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-346821(isoform-parent)|ensembl:ENSMUSG00000031870(gene)|ensembl:ENSMUST00000098986(transcript)	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007566"(embryo implantation)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071387"(cellular response to cortisol stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	go:"GO:0005634"(nucleus)|intact:EBI-12591658(see-also)	-	-	figure legend:7B|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-uterus)|taxid:10090(mouse uterus)	-	2016/11/01	2017/02/07	rogid:VWXpbjrIKqg9xJhIxSW3GSRQADA10090	rogid:Djegi76L43gige+6CTDtxQ/aTa410090	rigid:9DsS4o9ozmDHa/mYBCOIekrqtQc	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06401-2	uniprotkb:Q13886	intact:EBI-12590494	intact:EBI-12591669|ensembl:ENSP00000366330|uniprotkb:B2R943|uniprotkb:Q16196	psi-mi:p06401-2(display_long)|uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 3(gene name synonym)|uniprotkb:PR-A(isoform synonym)|uniprotkb:PRA(isoform synonym)	psi-mi:klf9_human(display_long)|uniprotkb:KLF9(gene name)|psi-mi:KLF9(display_short)|uniprotkb:BTEB(gene name synonym)|uniprotkb:BTEB1(gene name synonym)|uniprotkb:Basic transcription element-binding protein 1(gene name synonym)|uniprotkb:GC-box-binding protein 1(gene name synonym)|uniprotkb:Transcription factor BTEB1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2003)	pubmed:12672823|imex:IM-25653	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13642861	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78539(isoform-parent)	ensembl:ENSG00000119138(gene)|ensembl:ENST00000377126(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071387"(cellular response to cortisol stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001197.1	go:"GO:0005634"(nucleus)|intact:EBI-12591697(see-also)	isoform-comment:Produced by alternative promoter usage.	-	figure legend:7B|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d)|taxid:9606(human breast cancer tumour cell line-epithelial cells)	-	2016/11/01	2017/02/07	rogid:kP8B/pWHRF5MNGhAZmAtDReDiWw9606	rogid:zj1YiIXlwMQISuySS0i42wwnn0w9606	rigid:cYsu5COwz3Eu80J0WCJdJeQCahI	true	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17693-3	uniprotkb:P17693-3	intact:EBI-16586491|ensembl:ENSP00000366011|ensembl:ENSP00000373117|ensembl:ENSP00000389969|ensembl:ENSP00000410247|ensembl:ENSP00000413926|ensembl:ENSP00000416408|ensembl:ENSP00000479399|ensembl:ENSP00000401326	intact:EBI-16586491|ensembl:ENSP00000366011|ensembl:ENSP00000373117|ensembl:ENSP00000389969|ensembl:ENSP00000410247|ensembl:ENSP00000413926|ensembl:ENSP00000416408|ensembl:ENSP00000479399|ensembl:ENSP00000401326	psi-mi:p17693-3(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G3(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)	psi-mi:p17693-3(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G3(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)	psi-mi:"MI:0982"(electrophoretic mobility-based method)	HoWangYin et al. (2012)	pubmed:22802125|imex:IM-26243	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16586477	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204632(gene)|ensembl:ENSG00000206506(gene)|ensembl:ENSG00000230413(gene)|ensembl:ENSG00000233095(gene)|ensembl:ENSG00000235346(gene)|ensembl:ENSG00000235680(gene)|ensembl:ENSG00000237216(gene)|ensembl:ENSG00000276051(gene)|ensembl:ENST00000376815(transcript)|ensembl:ENST00000383622(transcript)|ensembl:ENST00000415687(transcript)|ensembl:ENST00000429890(transcript)|ensembl:ENST00000445373(transcript)|ensembl:ENST00000448306(transcript)|ensembl:ENST00000457132(transcript)|ensembl:ENST00000622601(transcript)|intact:EBI-1043063(isoform-parent)	ensembl:ENSG00000204632(gene)|ensembl:ENSG00000206506(gene)|ensembl:ENSG00000230413(gene)|ensembl:ENSG00000233095(gene)|ensembl:ENSG00000235346(gene)|ensembl:ENSG00000235680(gene)|ensembl:ENSG00000237216(gene)|ensembl:ENSG00000276051(gene)|ensembl:ENST00000376815(transcript)|ensembl:ENST00000383622(transcript)|ensembl:ENST00000415687(transcript)|ensembl:ENST00000429890(transcript)|ensembl:ENST00000445373(transcript)|ensembl:ENST00000448306(transcript)|ensembl:ENST00000457132(transcript)|ensembl:ENST00000622601(transcript)|intact:EBI-1043063(isoform-parent)	intact:EBI-15484467(see-also)	-	-	figure legend:2B|comment:"homodimers of HLA-G3 (alpha1 domain, lane 4) were never observed"|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-m8)|taxid:9606(human M8 metastatic melanoma cell line)	-	2017/07/19	2017/11/07	rogid:B4ZEzl2AS94FvVQ18pw83ClzmgU9606	rogid:B4ZEzl2AS94FvVQ18pw83ClzmgU9606	rigid:yXvf4qwLNEgprc354L0SmyNe8VA	true	-	-	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15409-6	uniprotkb:Q16650	intact:EBI-16595062|ensembl:ENSP00000353367	intact:EBI-1047158|ensembl:ENSP00000374205|uniprotkb:Q14DC5|uniprotkb:Q53TH0|uniprotkb:B2R6G5|uniprotkb:Q56A81|uniprotkb:B0AZS4	psi-mi:o15409-6(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2-S(isoform synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym)	psi-mi:tbr1_human(display_long)|uniprotkb:TES-56(gene name synonym)|uniprotkb:TBR1(gene name)|psi-mi:TBR1(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Deriziotis et al. (2014)	imex:IM-26315|pubmed:25232744	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16595054	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128573(gene)|ensembl:ENST00000360232(transcript)|intact:EBI-983612(isoform-parent)	refseq:NP_006584.1|ensembl:ENSG00000136535(gene)|ensembl:ENST00000389554(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021764"(amygdala development)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030902"(hindbrain development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|mint:Q16650	intact:EBI-16595006(see-also)	-	-	figure legend:6B-3|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/10/16	2017/11/16	rogid:9VOYJNViWannb6eLUUTa1shz/rE9606	rogid:qD1euHkX/welvC2klFM95IiAiWE9606	rigid:3bdV0N+Gtrrs2e0s5BNnlHFVS6s	true	renilla luciferase protein tag:n-n	yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O15409-6	uniprotkb:Q16650	intact:EBI-16595062|ensembl:ENSP00000353367	intact:EBI-1047158|ensembl:ENSP00000374205|uniprotkb:Q14DC5|uniprotkb:Q53TH0|uniprotkb:B2R6G5|uniprotkb:Q56A81|uniprotkb:B0AZS4	psi-mi:o15409-6(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2-S(isoform synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym)	psi-mi:tbr1_human(display_long)|uniprotkb:TES-56(gene name synonym)|uniprotkb:TBR1(gene name)|psi-mi:TBR1(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Deriziotis et al. (2014)	imex:IM-26315|pubmed:25232744	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16595150	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128573(gene)|ensembl:ENST00000360232(transcript)|intact:EBI-983612(isoform-parent)	refseq:NP_006584.1|ensembl:ENSG00000136535(gene)|ensembl:ENST00000389554(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021764"(amygdala development)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030902"(hindbrain development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|mint:Q16650	go:"GO:0005634"(nucleus)|intact:EBI-16595119(see-also)	-	-	figure legend:6C-3|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/10/16	2017/11/16	rogid:9VOYJNViWannb6eLUUTa1shz/rE9606	rogid:qD1euHkX/welvC2klFM95IiAiWE9606	rigid:3bdV0N+Gtrrs2e0s5BNnlHFVS6s	true	mcherry fluorescent protein tag:n-n	yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O15409-6	uniprotkb:Q16650	intact:EBI-16595062|ensembl:ENSP00000353367	intact:EBI-1047158|ensembl:ENSP00000374205|uniprotkb:Q14DC5|uniprotkb:Q53TH0|uniprotkb:B2R6G5|uniprotkb:Q56A81|uniprotkb:B0AZS4	psi-mi:o15409-6(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2-S(isoform synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym)	psi-mi:tbr1_human(display_long)|uniprotkb:TES-56(gene name synonym)|uniprotkb:TBR1(gene name)|psi-mi:TBR1(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Deriziotis et al. (2014)	imex:IM-26315|pubmed:25232744	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16628348	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128573(gene)|ensembl:ENST00000360232(transcript)|intact:EBI-983612(isoform-parent)	refseq:NP_006584.1|ensembl:ENSG00000136535(gene)|ensembl:ENST00000389554(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021764"(amygdala development)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030902"(hindbrain development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|mint:Q16650	intact:EBI-16595119(see-also)|go:"GO:0005634"(nucleus)	-	-	negative:The interaction does not occur under these experimental conditions|figure legend:Supplementary fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line)	-	2017/10/16	2017/11/17	rogid:9VOYJNViWannb6eLUUTa1shz/rE9606	rogid:qD1euHkX/welvC2klFM95IiAiWE9606	rigid:3bdV0N+Gtrrs2e0s5BNnlHFVS6s	true	mcherry fluorescent protein tag:n-n	yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P12956	uniprotkb:Q96EV8-2	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	intact:EBI-16749183|ensembl:ENSP00000344718	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:q96ev8-2(display_long)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:My031(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oyama et al. (2008)	imex:IM-26272|pubmed:19142223	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16749216	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	ensembl:ENSG00000047579(gene)|ensembl:ENST00000338950(transcript)|intact:EBI-465804(isoform-parent)|uniprotkb:Q96EV8-2(isoform-parent)	intact:EBI-16749172(see-also)|intact:EBI-16749191(see-also)	-	isoform-comment:May be due to intron retention.	figure legend:Fig. 4C|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2018/01/29	2018/01/29	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:WQesmKAdUqoqnBiR4Zr65tjvSXk9606	rigid:YO4bKujBPdmtZWvmvKLjriXABZ4	true	v5 tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P13010	uniprotkb:Q96EV8-2	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	intact:EBI-16749183|ensembl:ENSP00000344718	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:q96ev8-2(display_long)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:My031(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Oyama et al. (2008)	imex:IM-26272|pubmed:19142223	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16749241	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	ensembl:ENSG00000047579(gene)|ensembl:ENST00000338950(transcript)|intact:EBI-465804(isoform-parent)|uniprotkb:Q96EV8-2(isoform-parent)	intact:EBI-16749233(see-also)|intact:EBI-16749225(see-also)	-	isoform-comment:May be due to intron retention.	negative:The interaction does not occur under these experimental conditions.|figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2018/01/29	2018/01/29	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	rogid:WQesmKAdUqoqnBiR4Zr65tjvSXk9606	rigid:Ep2AToOMbuDLJn3pxKRXAfgBukc	true	v5 tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67775-2	uniprotkb:Q9Y570	intact:EBI-16766021	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766012	intact-miscore:0.40	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	intact:EBI-16765968(secondary-ac)	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 4Ci,   5G.|comment:clone 3.4|negative:The  interaction  does  not  occur  under   these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rigid:M5ehsHXvI8o7Z7cKEURTQNH1Ljo	true	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P67775-2	uniprotkb:P30153	intact:EBI-16766021	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766012	intact-miscore:0.40	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-16765968(secondary-ac)	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 4Ci,   5G.|comment:clone 3.4|negative:The  interaction  does  not  occur  under   these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rigid:M5ehsHXvI8o7Z7cKEURTQNH1Ljo	true	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95718-3	uniprotkb:P03372	intact:EBI-20585243	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	psi-mi:o95718-3(display_long)|uniprotkb:ESRRB(gene name)|psi-mi:ESRRB(display_short)|uniprotkb:ERR beta-2(gene name synonym)|uniprotkb:Estrogen receptor-like 2(gene name synonym)|uniprotkb:Estrogen-related receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 2(gene name synonym)|uniprotkb:ERRbeta-short-form(isoform synonym)|uniprotkb:ERRB2(gene name synonym)|uniprotkb:ESRL2(gene name synonym)|uniprotkb:NR3B2(gene name synonym)	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Bombail et al. (2010)	imex:IM-26439|pubmed:19755138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20586209	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1042744(isoform-parent)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	intact:EBI-20585379(see-also)	-	-	figure legend:Figure 6|comment:After incubation of cells with PPT, there was a significant increase in FRET signal between ERalpha and ERRbeta-long form whereas there was no significant increase in the FRET signal in the presence of ERalpha and ERRbeta-short form.|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ishikawa_cell_line)|taxid:9606(human Ishikawa ERalpha-positive endometrium adenocarcinoma)	-	2018/05/08	2018/06/12	rogid:UtZYFAwSICzVqImLfk8DS2JwtDY9606	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rigid:Zvy1gDyqU5zRcH+6qL4NA0gnNt4	true	yellow fluorescent protein tag:n-n	cyan fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q13501-2	uniprotkb:Q969Q1	intact:EBI-21530341|ensembl:ENSP00000353944	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:q13501-2(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nowak et al. (2019)	pubmed:31391242|imex:IM-25805|doi:10.1242/jcs.233395	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21995482	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000161011(gene)|ensembl:ENST00000360718(transcript)|intact:EBI-307104(isoform-parent)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168	intact:EBI-21995465(see-also)	isoform-comment:Initiator Met-1 is removed. Contains a N-acetylalanine at position 2.	-	figure legend:1C|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2019/09/03	2019/09/05	rogid:NWg5AQiCzIuhPA334HF0nsthaQE9606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	rigid:uyvoPpIsKnKkTjckK6405CCZZ+g	true	flag tag:n-n	tandem tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35372	uniprotkb:Q5T9L3-2	intact:EBI-2624570|uniprotkb:B0FXJ1|uniprotkb:B8Q1L8|uniprotkb:B8Q1L9|uniprotkb:Q6UPP1|uniprotkb:Q86V80|uniprotkb:G8XRH8|uniprotkb:B2R9S7|uniprotkb:B8Q1L7|uniprotkb:Q12930|uniprotkb:Q4VWM1|uniprotkb:Q4VWM2|uniprotkb:Q4VWM3|uniprotkb:Q4VWM4|uniprotkb:Q4VWM6|uniprotkb:Q4VWX6|uniprotkb:Q5TDA1|uniprotkb:Q6UQ80|uniprotkb:Q7Z2D8|uniprotkb:Q8IWW3|uniprotkb:Q8IWW4|uniprotkb:Q9UCZ4|uniprotkb:Q9UN57|uniprotkb:G8XRH6|ensembl:ENSP00000328264|uniprotkb:E7EWZ3	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:oprm_human(display_long)|uniprotkb:OPRM1(gene name)|psi-mi:OPRM1(display_short)|uniprotkb:MOR1(gene name synonym)|uniprotkb:Mu opioid receptor(gene name synonym)|uniprotkb:Mu opiate receptor(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118916	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001272453.1|refseq:NP_001272455.1|refseq:NP_001272456.1|refseq:NP_001272457.1|refseq:NP_001138752.1|refseq:NP_001138753.1|refseq:NP_001272452.1|refseq:NP_000905.3|refseq:NP_001008503.2|refseq:NP_001008504.2|refseq:NP_001008505.2|refseq:NP_001138751.1|refseq:NP_001138754.1|refseq:NP_001138755.1|refseq:NP_001138756.1|refseq:NP_001138757.1|refseq:NP_001138758.1|refseq:NP_001138759.1|refseq:XP_016866395.1|ensembl:ENSG00000112038(gene)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007600"(sensory perception)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|ensembl:ENST00000330432(transcript)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0042755"(eating behavior)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0005768"(endosome)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P35372|reactome:R-HSA-111885|reactome:R-HSA-202040|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|reactome:R-HSA-418594|reactome:R-HSA-6785807|reactome:R-HSA-9022699|reactome:R-HSA-375276	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	intact:EBI-22118896(see-also)	-	-	figure legend:fig. 5A|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2020/04/02	rogid:pfkhVhvpn9gSXiBRs1OBXJBCI3s9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:iOzFc5BSSZawFoRcWA2bFwGL1/8	true	sufficient binding region:166-187|glutathione s tranferase tag:n-n	sufficient binding region:505-543|s tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T9L3-1	uniprotkb:Q5T9L3-2	intact:EBI-22114623|ensembl:ENSP00000262348	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118943	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	intact:EBI-22118931(see-also)	-	-	figure legend:fig. 5B|negative:The interaction does not occur under these experimental conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2019/10/29	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:DMS50QzlLZ5AEDSkiT1QM6Q8EQE	true	sufficient binding region:493-541|s tag:?-?	sufficient binding region:505-543|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BYF1	uniprotkb:P0DTC2	intact:EBI-7730807|ensembl:ENSP00000252519|ensembl:ENSP00000389326|ensembl:ENSP00000504103|ensembl:ENSP00000505992|intact:EBI-25767352|uniprotkb:Q9UFZ6|uniprotkb:Q9NRA7|intact:MINT-4538816|uniprotkb:C7ECU1|uniprotkb:Q6UWP0|uniprotkb:Q86WT0|uniprotkb:A0A7D6JAD5|intact:EBI-15814450	intact:EBI-25474821	psi-mi:ace2_human(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:UNQ868/PRO1885(orf name)|uniprotkb:Angiotensin-converting enzyme homolog(gene name synonym)|uniprotkb:Metalloprotease MPROT15(gene name synonym)|uniprotkb:Angiotensin-converting enzyme-related carboxypeptidase(gene name synonym)	psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Onabajo et al. (2020)	pubmed:33077916|imex:IM-28237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25767339	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000252519(transcript)|ensembl:ENST00000427411(transcript)|ensembl:ENST00000678073(transcript)|ensembl:ENST00000680121(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006508"(proteolysis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|ensembl:ENSG00000130234(gene)|go:"GO:0051957"(positive regulation of amino acid transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905737"(positive regulation of L-proline import across plasma membrane)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|interpro:IPR031588|mint:Q9BYF1|rcsb pdb:1R42|rcsb pdb:1R4L|rcsb pdb:1XJP|rcsb pdb:2AJF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3KBH|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:6ACG|rcsb pdb:6ACJ|rcsb pdb:6ACK|rcsb pdb:6CS2|rcsb pdb:6LZG|rcsb pdb:6M0J|rcsb pdb:6M17|rcsb pdb:6M18|go:"GO:0050727"(regulation of inflammatory response)|rcsb pdb:6M1D|rcsb pdb:6VW1|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7BH9|rcsb pdb:7CT5|rcsb pdb:7DDO|rcsb pdb:7DDP|rcsb pdb:7DF4|rcsb pdb:7DMU|rcsb pdb:7DWX|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7JVO|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7L0N|rcsb pdb:7L7F|rcsb pdb:7LO4|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7NXC|reactome:R-HSA-2022377|reactome:R-HSA-9678110|reactome:R-HSA-9679191|reactome:R-HSA-9694614|rcsb pdb:7KNI|dip:DIP-44689N|refseq:NP_068576.1	interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635	intact:EBI-25767315(see-also)	comment:mint|function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses	-	figure legend:7A|comment:"When cells overexpressing GFP or Myc-DDK-tagged dACE2 or ACE2 were treated with biotinylated spike protein RBD (Figure 6A), dACE2 failed to bind and internalize the RBD."|negative:The interaction does not occur under these experimental conditions.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/04	2021/02/12	rogid:ZxuR6gzxz4Ns+hYH5uksGdn8S7o9606	rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049	rigid:HsUltcKq/ARrTkmVPSSTEFwwdk8	true	flag tag:c-c|myc tag:c-c	sufficient binding region:319-541|biotin tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9BYF1	uniprotkb:P0DTC2	intact:EBI-7730807|ensembl:ENSP00000252519|ensembl:ENSP00000389326|ensembl:ENSP00000504103|ensembl:ENSP00000505992|intact:EBI-25767352|uniprotkb:Q9UFZ6|uniprotkb:Q9NRA7|intact:MINT-4538816|uniprotkb:C7ECU1|uniprotkb:Q6UWP0|uniprotkb:Q86WT0|uniprotkb:A0A7D6JAD5|intact:EBI-15814450	intact:EBI-25474821	psi-mi:ace2_human(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:UNQ868/PRO1885(orf name)|uniprotkb:Angiotensin-converting enzyme homolog(gene name synonym)|uniprotkb:Metalloprotease MPROT15(gene name synonym)|uniprotkb:Angiotensin-converting enzyme-related carboxypeptidase(gene name synonym)	psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Onabajo et al. (2020)	pubmed:33077916|imex:IM-28237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25767423	intact-miscore:0.46	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000252519(transcript)|ensembl:ENST00000427411(transcript)|ensembl:ENST00000678073(transcript)|ensembl:ENST00000680121(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006508"(proteolysis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|ensembl:ENSG00000130234(gene)|go:"GO:0051957"(positive regulation of amino acid transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905737"(positive regulation of L-proline import across plasma membrane)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|interpro:IPR031588|mint:Q9BYF1|rcsb pdb:1R42|rcsb pdb:1R4L|rcsb pdb:1XJP|rcsb pdb:2AJF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3KBH|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:6ACG|rcsb pdb:6ACJ|rcsb pdb:6ACK|rcsb pdb:6CS2|rcsb pdb:6LZG|rcsb pdb:6M0J|rcsb pdb:6M17|rcsb pdb:6M18|go:"GO:0050727"(regulation of inflammatory response)|rcsb pdb:6M1D|rcsb pdb:6VW1|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7BH9|rcsb pdb:7CT5|rcsb pdb:7DDO|rcsb pdb:7DDP|rcsb pdb:7DF4|rcsb pdb:7DMU|rcsb pdb:7DWX|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7JVO|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7L0N|rcsb pdb:7L7F|rcsb pdb:7LO4|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7NXC|reactome:R-HSA-2022377|reactome:R-HSA-9678110|reactome:R-HSA-9679191|reactome:R-HSA-9694614|rcsb pdb:7KNI|dip:DIP-44689N|refseq:NP_068576.1	interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635	intact:EBI-25767399(see-also)	comment:mint|function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses	-	negative:The interaction does not occur under these experimental conditions.|figure legend:7 B/C/E/F|comment:"When cells overexpressing GFP or Myc-DDK-tagged dACE2 or ACE2 were treated with biotinylated spike protein RBD (Figure 6A), dACE2 failed to bind and internalize the RBD."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/04	2021/02/12	rogid:ZxuR6gzxz4Ns+hYH5uksGdn8S7o9606	rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049	rigid:HsUltcKq/ARrTkmVPSSTEFwwdk8	true	flag tag:c-c|myc tag:c-c	sufficient binding region:319-541|biotin tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O75531	uniprotkb:Q8NAG6-1	intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760	intact:EBI-27052205	psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym)	psi-mi:q8nag6-1(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 41(gene name synonym)|uniprotkb:LEM-domain containing protein 3(gene name synonym)|uniprotkb:ANKLE1(gene name)|psi-mi:ANKLE1(display_short)|uniprotkb:ANKRD41(gene name synonym)|uniprotkb:LEM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brachner et al. (2012)	imex:IM-29138|pubmed:22399800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27052243	intact-miscore:0.40	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N	intact:EBI-28918916(isoform-parent)	intact:EBI-27052213(see-also)	-	-	figure legend:Fig. 3B|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/29	2021/08/04	rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606	rogid:aBjMl3dpK4H1j7RMcgCY//VB49s9606	rigid:4ABIBgFNaqhmxHUBmCsUPQh8Y4o	true	-	his tag:?-?|v5 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)