MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. EMBO reports 2018 imex curation Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Chen ZS., Li L., Peng S., Chen FM., Zhang Q., An Y., Lin X., Li W., Koon AC., Chan TF., Lau KF., Ngo JCK., Wong WT., Kwan KM., Chan HYE. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. hyechan@cuhk.edu.hk 29-Mar-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Chen ZS., Li L., Peng S., Chen FM., Zhang Q., An Y., Lin X., Li W., Koon AC., Chan TF., Lau KF., Ngo JCK., Wong WT., Kwan KM., Chan HYE. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. the antibody anti‐Dvl (sc‐8027, Santa Cruz Biotechnology) recognize Dvl-3. hyechan@cuhk.edu.hk Accepted 2021-FEB-24 AT 14:24 GMT AT 14:24 GMT by MGT EMBO reports 2018 Only protein-protein interactions imex curation imex curation Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. EMBO reports 2018 imex curation Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Chen ZS., Li L., Peng S., Chen FM., Zhang Q., An Y., Lin X., Li W., Koon AC., Chan TF., Lau KF., Ngo JCK., Wong WT., Kwan KM., Chan HYE. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. hyechan@cuhk.edu.hk 29-Mar-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. confocal microscopy confocal microscopy immunocytochemistry immunocytochemistry Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Maziuk BF., Apicco DJ., Cruz AL., Jiang L., Ash PEA., da Rocha EL., Zhang C., Yu WH., Leszyk J., Abisambra JF., Li H., Wolozin B., Chen ZS., Li L., Peng S., Chen FM., Zhang Q., An Y., Lin X., Li W., Koon AC., Chan TF., Lau KF., Ngo JCK., Wong WT., Kwan KM., Chan HYE. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. the antibody anti‐Dvl (sc‐8027, Santa Cruz Biotechnology) recognize Dvl-3. hyechan@cuhk.edu.hk Accepted 2021-FEB-24 AT 14:24 GMT AT 14:24 GMT by MGT EMBO reports 2018 Only protein-protein interactions imex curation imex curation dvl3_human Segment polarity protein dishevelled homolog DVL-3 DVL3 KIAA0208 DSH homolog 3 protein protein human Homo sapiens Human MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM DIP protein Q92997 original sequence version: 110 B1A55EBF9507D06E fuzzy_human Protein fuzzy homolog FUZ FY protein protein human Homo sapiens Human MGEEGTGGTVHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSARTENTTVVWKSFHDSITLIVLSSEVGISELRLERLLQMVFGAMVLLVGLEELTNIRNVERLKKDLRASYCLIDSFLGDSELIGDLTQCVDCVIPPEGSLLQEALSGFAEAAGTTFVSLVVSGRVVAATEGWWRLGTPEAVLLPWLVGSLPPQTARDYPVYLPHGSPTVPHRLLTLTLLPSLELCLLCGPSPPLSQLYPQLLERWWQPLLDPLRACLPLGPRALPSGFPLHTDILGLLLLHLELKRCLFTVEPLGDKEPSPEQRRRLLRNFYTLVTSTHFPPEPGPPEKTEDEVYQAQLPRACYLVLGTEEPGTGVRLVALQLGLRRLLLLLSPQSPTHGLRSLATHTLHALTPLL 9967702DC289CD6F dvl3-1 1 4 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed flag tag flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Figure EV1 fuz-dvl3-1 2 4 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed gfp tag gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 3 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed flag tag flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range colocalization colocalization Figure EV1E