DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Science (New York, N.Y.) 1994 imex curation Kaushal S., Schneider JW., Nadal-Ginard B., Mahdavi V. Vijay Mahdavi 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kaushal S., Schneider JW., Nadal-Ginard B., Mahdavi V. Vijay Mahdavi Accepted 2021-APR-28 AT 12:56 BST AT 12:56 BST by PPORRAS Science (New York, N.Y.) 1994 Only protein-protein interactions imex curation imex curation Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Science (New York, N.Y.) 1994 imex curation Kaushal S., Schneider JW., Nadal-Ginard B., Mahdavi V. Vijay Mahdavi 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro pull down pull down predetermined predetermined participant predetermined Kaushal S., Schneider JW., Nadal-Ginard B., Mahdavi V. Vijay Mahdavi Accepted 2021-APR-28 AT 12:56 BST AT 12:56 BST by PPORRAS Science (New York, N.Y.) 1994 Only protein-protein interactions imex curation imex curation mef2a_mouse Myocyte-specific enhancer factor 2A Mef2a protein protein mouse Mus musculus Mouse MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLADSSMLSPPPATLHRNVSPGAPQRPPSTGSASGMLSTTDLTVPNGAGNSPVGNGFVNSRASPNLIGNTGANSLGKVMPTKSPPPPGGGSLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNAQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNINIKSEPISPPRDRMTPSGFQQQQQQPQQQPPPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDTWVT FE291C3E3E0A5E70 mef2a_human Myocyte-specific enhancer factor 2A MEF2A MEF2 Serum response factor-like protein 1 protein protein human Homo sapiens Human MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT 362BA4FBCC792CE2 myog_mouse Myogenin Myog MYOD1-related protein protein protein mouse Mus musculus Mouse MELYETSPYFYQEPHFYDGENYLPVHLQGFEPPGYERTELSLSPEARGPLEEKGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPMVPSECNSHSASCSPEWGNALEFGPNPGDHLLAADPTDAHNLHSLTSIVDSITVEDMSVAFPDETMPN DIP protein P12979 original sequence version: 69 mint Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein CC7352C1EDF9D3D8 myod1_mouse Myoblast determination protein 1 Myod1 Myod protein protein mouse Mus musculus Mouse MELLSPPLRDIDLTGPDGSLCSFETADDFYDDPCFDSPDLRFFEDLDPRLVHMGALLKPEEHAHFPTAVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDTAYYSEAARESRPGKSAAVSSLDCLSSIVERISTDSPAAPALLLADAPPESPPGPPEGASLSDTEQGTQTPSPDAAPQCPAGSNPNAIYQVL DIP protein P10085 original sequence version: 90 DIP protein P10085 original sequence version: 88 AEC6572277A78D54 mef2a-myog-1 1 5 unspecified role unspecified role prey prey native native mouse-c2c12 Mouse C3H muscle myoblast c2c12 Mouse C3H muscle myoblast 3 unspecified role unspecified role bait bait native native mouse-c2c12 Mouse C3H muscle myoblast c2c12 Mouse C3H muscle myoblast physical association physical association Fig 4 myog-mef2a-1 1 5 unspecified role unspecified role bait bait native native mouse-c2c12 Mouse C3H muscle myoblast c2c12 Mouse C3H muscle myoblast 3 unspecified role unspecified role prey prey native native mouse-c2c12 Mouse C3H muscle myoblast c2c12 Mouse C3H muscle myoblast physical association physical association Fig 4 mef2a-myod1-1 2 6 unspecified role unspecified role prey prey purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain vitvi vitvi Grape 4 unspecified role unspecified role bait bait purified purified GST tag GST tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) physical association physical association Fig 5 myod1-mef2a-1 2 6 unspecified role unspecified role prey prey purified purified region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 4 unspecified role unspecified role bait bait purified purified GST tag GST tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined vitvi vitvi Grape physical association physical association Fig 5