IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in molecular neuroscience 2018 imex curation Chiou TT., Long P., Schumann-Gillett A., Kanamarlapudi V., Haas SA., Harvey K., O'Mara ML., De Blas AL., Kalscheuer VM., Harvey RJ. Rare diseases - Interactions investigated in the context of Rare genetic disease r.j.harvey@usc.edu.au 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Chiou TT., Long P., Schumann-Gillett A., Kanamarlapudi V., Haas SA., Harvey K., O'Mara ML., De Blas AL., Kalscheuer VM., Harvey RJ. Rare diseases - Interactions investigated in the context of Rare genetic disease r.j.harvey@usc.edu.au Accepted 2020-MAR-06 AT 08:45 GMT AT 08:45 GMT by PPORRAS Frontiers in molecular neuroscience 2018 Only protein-protein interactions imex curation imex curation arhg9_human Rho guanine nucleotide exchange factor 9 ARHGEF9 KIAA0424 Collybistin PEM-2 homolog Rac/Cdc42 guanine nucleotide exchange factor 9 ARHDH9 protein protein human Homo sapiens Human MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDEVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNSARSVPPSYPPPQDPLNHGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK AAEE17366B46B707 phosphatidylinositol-3-phosphate phosphatidylinositol 3-phosphate phosphatidylinositol 3-phosphates PI(3)P PtdIns3P small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) arhgef9-phosphatidylinositol_3_phosphate-1 1 2 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed cell lysate cell lysate region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined O43307:p.Arg356Gln mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain R Q Tue Jun 30 17:55:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg356Gln' O43307:p.Arg356_Arg357delinsAsnAsn mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain RR NN Thu Mar 05 22:55:20 GMT 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg356_Arg357delinsAsnAsn]' Tue Jun 30 18:41:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg356_Arg357delinsAsnAsn' O43307:p.Arg290His mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain R H Tue Jun 30 18:18:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg290His' human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 3 unspecified role unspecified role bait bait purified purified chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association Fig. 2b