UniProt UniProt http://www.uniprot.org Interaction of the RcsB Response Regulator with Auxiliary Transcription Regulators in Escherichia coli. Interaction of the RcsB Response Regulator with Auxiliary Transcription Regulators in Escherichia coli. The Journal of biological chemistry 2016 imex curation Pannen D., Fabisch M., Gausling L., Schnetz K. schnetz@uni-koeln.de Only protein-protein interactions imex curation ecolx Escherichia coli gallex lex-a dimerization assay gallex predetermined predetermined participant predetermined Pannen D., Fabisch M., Gausling L., Schnetz K. One partner is fused to LexA(1–87)WT and the other partner is fused to a 408 mutant DNA-binding domain (LexA(1–87)408), in the case of homodimes, both proteins have the LexA(1–87)WT tag. Homo/heterodimers then bind to the hybrid operator and repress PsulA lacZ expression schnetz@uni-koeln.de Accepted 2020-JUL-02 AT 09:54 BST AT 09:54 BST by LIVIAP The Journal of biological chemistry 2016 Only protein-protein interactions imex curation imex curation malt_ecoli HTH-type transcriptional regulator MalT malT malA b3418 JW3381 ATP-dependent transcriptional activator MalT protein protein ecoli Escherichia coli (strain K12) MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV DIP protein P06993 original sequence version: null 9B27CE0F632AD417 narp_ecoli Nitrate/nitrite response regulator protein NarP narP b2193 JW2181 protein protein ecoli Escherichia coli (strain K12) MPEATPFQVMIVDDHPLMRRGVRQLLELDPGSEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ C7121668E3130956 rcsb_ecoli Transcriptional regulatory protein RcsB rcsB Capsular synthesis regulator component B JW2205 b2217 protein protein ecoli Escherichia coli (strain K12) MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD This sequence has been withdrawn from Uniprot. A78D1BD3004E0680 A78D1BD3004E0680 yhjb_ecoli Putative HTH-type transcriptional regulator YhjB yhjB b3520 JW3488 protein protein ecoli Escherichia coli (strain K12) MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLESYPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVPRDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNKEIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS DIP protein P37640 original sequence version: null D238AB59FE6ED109 ecpr_ecoli HTH-type transcriptional regulator EcpR ecpR matA ykgK JW5031 b0294 protein protein ecoli Escherichia coli (strain K12) MTWQSDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ 5A3676E17E9793B9 rcsa_ecoli Transcriptional regulatory protein RcsA rcsA Colanic acid capsular biosynthesis activation protein A JW1935 b1951 protein protein ecoli Escherichia coli (strain K12) MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQRIKLIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR This sequence has been withdrawn from Uniprot. 6DAA22097807AF62 6DAA22097807AF62 narl_ecoli Nitrate/nitrite response regulator protein NarL narL frdR b1221 JW1212 protein protein ecoli Escherichia coli (strain K12) MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF DIP protein P0AF28 original sequence version: 83 DIP protein P0AF28 original sequence version: 60 7DED78E4EF7EC57D csgd_ecoli CsgBAC operon transcriptional regulatory protein csgD b1040 JW1023 protein protein ecoli Escherichia coli (strain K12) MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR DIP protein P52106 original sequence version: null E1A5FD0DA1855DDE uvry_ecoli Response regulator UvrY yecB uvrY b1914 JW1899 protein protein ecoli Escherichia coli (strain K12) MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ This sequence has been withdrawn from Uniprot. 708E52D8BFA97716 708E52D8BFA97716 sdia_ecoli Regulatory protein SdiA sdiA b1916 JW1901 protein protein ecoli Escherichia coli (strain K12) MQDKDFFSWRRTMLLRFQRMETAEEVYHEIELQAQQLEYDYYSLCVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSEAQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSAREIPILSDELQLKMQLLVRESLMALMRLNDEIVMTPEMNFSKREKEILRWTAEGKTSAEIAMILSISENTVNFHQKNMQKKINAPNKTQVACYAAATGLI C04CCC50C06135C4 bglj_ecoli Transcriptional activator protein BglJ yjjR bglJ b4366 JW5955 protein protein ecoli Escherichia coli (strain K12) MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLIGSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREILRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCETSNVLHPY DIP protein P39404 original sequence version: null 5EED6E444409A010 dctr_ecoli HTH-type transcriptional regulator DctR yhiF dctR b3507 JW3475 protein protein ecoli Escherichia coli (strain K12) MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPEAAVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRHQHIDYLV DIP protein P37195 original sequence version: null F87354C3AB82BB83 uhpa_ecoli Transcriptional regulatory protein UhpA uhpA b3669 JW3644 protein protein ecoli Escherichia coli (strain K12) MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW 8F409F8AADE08276 fimz_ecoli Fimbriae Z protein ybcA fimZ b0535 JW5073 protein protein ecoli Escherichia coli (strain K12) MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRYLVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI B5AD1F551028D54C bglj-rcsb-1 1 12 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)408 tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 rcsa-rcsb-1 1 7 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)408 tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 ecpr-rcsb-1 1 6 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)408 tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 dctr-rcsb-1 1 13 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)408 tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 bglj-rcsb-2 1 12 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)408 tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 rcsb-rcsb-2 1 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 4 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1 fimz-fimz-1 1 15 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 narl-narl-1 1 8 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 8 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 narp-narp-1 1 3 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 uhpa-uhpa-1 1 14 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 14 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 uvry-uvry-1 1 10 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 csgd-csgd-2 1 9 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 9 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 sdia-sdia-1 1 11 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 11 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 yhjb-yhjb-1 1 5 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 5 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4 malt-malt-3 1 2 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 2 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed LexA(1–87)WT tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 4