DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure of a mitochondrial ribosome with minimal RNA. Structure of a mitochondrial ribosome with minimal RNA. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Sharma MR., Booth TM., Simpson L., Maslov DA., Agrawal RK. agrawal@wadsworth.org 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Sharma MR., Booth TM., Simpson L., Maslov DA., Agrawal RK. agrawal@wadsworth.org Accepted 2021-APR-06 AT 14:15 BST AT 14:15 BST by MARTA Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation rm04_human 39S ribosomal protein L4, mitochondrial MRPL4 Mitochondrial large ribosomal subunit protein uL4m CDABP0091 CGI-28 protein protein human Homo sapiens Human MLQFVRAGARAWLRPTGSQGLSSLAEEAARATENPEQVASEGLPEPVLRKVELPVPTHRRPVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEVRGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLAQDDLHIMDSLELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTFNLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFPRPLPHATQGPAATPYHC 8267C61C42BFCF07 rs8_ecoli 30S ribosomal protein S8 rpsH Small ribosomal subunit protein uS8 JW3268 b3306 protein protein ecoli Escherichia coli (strain K12) MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA DIP protein P0A7W7 original sequence version: 50 74641BC5021DA651 rm24_bovin 39S ribosomal protein L24, mitochondrial MRPL24 protein protein bovin Bos taurus (Bovine) Bovine MRLSALLALASKVTLPPNYRYGMSRPGSLADKKKNPPGTRRRRVAVEPIPEEDWHLFCGDRVEILEGKDAGKQGKVVQVIRQRNWVVVEGLNTHYRYVGKTVDFRGTMVPSEAPLLHNQVKLVDPMDRKPTEVEWRFTEAGERVRVSTRSGRIIPKPDVPRADGIVPETWIDGPKDTSVEDALEKTYVPRLKTLEEEVMEAMGIQETRRHKKVYWY D462E7D0100C9900 rm11_bovin 39S ribosomal protein L11, mitochondrial MRPL11 protein protein bovin Bos taurus (Bovine) Bovine MSKLSRATRALRKPEAEGVIRTILRAGQAMPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARNTGKEVAGLVTLKHVYEIARVKAQDDAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERALFLAAQKEADLAAQAEAAKK 7067B2DAAD9EDE7A rs17_ecoli 30S ribosomal protein S17 rpsQ neaA b3311 JW3273 Small ribosomal subunit protein uS17 protein protein ecoli Escherichia coli (strain K12) MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL DIP protein P0AG63 original sequence version: 46 FC64AF04841842F6 rm22_bovin 39S ribosomal protein L22, mitochondrial MRPL22 protein protein bovin Bos taurus (Bovine) Bovine MAAVILERLGALWVQNLRGKLALGILPQSHIHTSASLEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPPEAPKTAVTHAKEYIQELRNRTIIHAL 00DE97CA41A86804 rl3_ecoli 50S ribosomal protein L3 rplC Large ribosomal subunit protein uL3 JW3282 b3320 protein protein ecoli Escherichia coli (strain K12) MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA DIP protein P60438 original sequence version: null EA8E10EDD2C0A8FD rm27_human 39S ribosomal protein L27, mitochondrial Mitochondrial large ribosomal subunit protein bL27m HSPC250 MRPL27 protein protein human Homo sapiens Human MASVVLALRTRTAVTSLLSPTPATALAVRYASKKSGGSSKNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHPRNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML 90945F471E80EFB6 rs16_ecoli 30S ribosomal protein S16 rpsP Small ribosomal subunit protein bS16 JW2590 b2609 protein protein ecoli Escherichia coli (strain K12) MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA F94D07049A6D489D rs6_ecoli 30S ribosomal protein S6 rpsF Small ribosomal subunit protein bS6 JW4158 b4200 protein protein ecoli Escherichia coli (strain K12) MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEEEEEE DIP protein P02358 original sequence version: 115 DIP protein P02358 original sequence version: 128 DIP protein P02358 original sequence version: null F4CC629711C1FD0E rs9_ecoli 30S ribosomal protein S9 rpsI Small ribosomal subunit protein uS9 JW3199 b3230 protein protein ecoli Escherichia coli (strain K12) MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR DIP protein P0A7X3 original sequence version: 55 757D599168812806 rl29_ecoli 50S ribosomal protein L29 rpmC Large ribosomal subunit protein uL29 JW3274 b3312 protein protein ecoli Escherichia coli (strain K12) MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA DIP protein P0A7M6 original sequence version: 56 DAEF8F126B0AA077 rm33_human 39S ribosomal protein L33, mitochondrial MRPL33 C2orf1 Mitochondrial large ribosomal subunit protein bL33m protein protein human Homo sapiens Human MFLSAVFFAKSKSKNILVRMVSEAGTGFCFNTKRNRLREKLTLLHYDPVVKQRVLFVEKKKIRSL F32C16A238A5D08A rs11_ecoli 30S ribosomal protein S11 rpsK Small ribosomal subunit protein uS11 JW3259 b3297 protein protein ecoli Escherichia coli (strain K12) MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV DIP protein P0A7R9 original sequence version: 55 DIP protein P0A7R9 original sequence version: 66 0C759DDA60E89C0C rl30_ecoli 50S ribosomal protein L30 rpmD Large ribosomal subunit protein uL30 JW3264 b3302 protein protein ecoli Escherichia coli (strain K12) MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE 08F427BBB6F820A4 rm16_human 39S ribosomal protein L16, mitochondrial MRPL16 Mitochondrial large ribosomal subunit protein uL16m PNAS-111 protein protein human Homo sapiens Human MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV 8A42A67DA80A6FEF rs5_ecoli 30S ribosomal protein S5 rpsE spc b3303 JW3265 Small ribosomal subunit protein uS5 protein protein ecoli Escherichia coli (strain K12) MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK DIP protein P0A7W1 original sequence version: null 0B7EA2CB34018CAB rl14_ecoli 50S ribosomal protein L14 rplN Large ribosomal subunit protein uL14 JW3272 b3310 protein protein ecoli Escherichia coli (strain K12) MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL DIP protein P0ADY3 original sequence version: 46 192ACB1623979510 rl13_ecoli 50S ribosomal protein L13 rplM Large ribosomal subunit protein uL13 JW3200 b3231 protein protein ecoli Escherichia coli (strain K12) MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI DIP protein P0AA10 original sequence version: 47 58B45EF9EB75FDCD rl20_ecoli 50S ribosomal protein L20 rplT pdzA b1716 JW1706 Large ribosomal subunit protein bL20 protein protein ecoli Escherichia coli (strain K12) MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA DIP protein P0A7L3 original sequence version: 54 E60AFDBB6F05DFB3 rm02_bovin 39S ribosomal protein L2, mitochondrial MRPL2 protein protein bovin Bos taurus (Bovine) Bovine MALRVVTRALGSLSLTPRIAAVPGPSLLPAAQVTNNVLLQLPSASMLLPSRPLLTSVALSAKFVSWKSRTKYTTMPVKMRKSGGRNHTGRIQVHGIGGGHKQRYRMIDFLRFRPEQESKPGPFEEKVIVVRYDPCRSADIALVAGGNRKRWIIATENMKAGDTILNSDHIGRMAVAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRAAGTCGVLLRKVNGTAIIQLPSKRQMQVLETCTATVGRVSNVDHNKRVIGKAGRNRWLGKRPNSGRWHRKGGWAGRKIRPLPPMKSYVKLPSAAAQN 6E616AF1E0B405BF rs12_ecoli 30S ribosomal protein S12 rpsL strA b3342 JW3304 Small ribosomal subunit protein uS12 protein protein ecoli Escherichia coli (strain K12) MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA DIP protein P0A7S3 original sequence version: 61 94A57F4C4FF0FC5E rl15_ecoli 50S ribosomal protein L15 rplO Large ribosomal subunit protein uL15 JW3263 b3301 protein protein ecoli Escherichia coli (strain K12) MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE DIP protein P02413 original sequence version: 105 DIP protein P02413 original sequence version: null 53D14CD948815FD9 rs18_ecout 30S ribosomal protein S18 rpsR UTI89_C4802 protein protein ecout Escherichia coli (strain UTI89 / UPEC) MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ AB2E8288901B73B8 rl21_ecoli 50S ribosomal protein L21 rplU Large ribosomal subunit protein bL21 JW3153 b3186 protein protein ecoli Escherichia coli (strain K12) MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA DIP protein P0AG48 original sequence version: 44 9221F104EC9C8CDB rs15_eco57 30S ribosomal protein S15 rpsO Z4526 ECs4046 protein protein eco57 Escherichia coli O157:H7 MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTRLIERLGLRR AABE156674B99B1C rm17_bovin 39S ribosomal protein L17, mitochondrial MRPL17 protein protein bovin Bos taurus (Bovine) Bovine MRLSFAAAISHGRVYRRLGLGPESRIHLLQNLLTGLVRHERIEASWARVDELRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYQGQNGGYTRMLQIPNRNQQDRAKMAVIEYKGNCLPPLPLPRRDSNLTLLNQLLRGLRQDQEASTRSSHPAQTPEV 3BF66CD4421BB948 rl9_ecoli 50S ribosomal protein L9 rplI Large ribosomal subunit protein bL9 JW4161 b4203 protein protein ecoli Escherichia coli (strain K12) MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE DIP protein P0A7R1 original sequence version: 58 DIP protein P0A7R1 original sequence version: 65 DIP protein P0A7R1 original sequence version: 69 F8FF527DBB9458CA rl23_ecoli 50S ribosomal protein L23 rplW Large ribosomal subunit protein uL23 JW3280 b3318 protein protein ecoli Escherichia coli (strain K12) MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE DIP protein P0ADZ0 original sequence version: 47 30CD1D77CC7CF9EB rpse-rpsf-1 1 25 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 6 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 10 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 27 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 23 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 15 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 12 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 11 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 18 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro physical association physical association Fig 1, Fig S1 mrpl11-mrpl16-1 1 14 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 16 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 13 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 9 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 4 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 30 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 7 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 26 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 21 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 28 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 17 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 24 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 19 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 20 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 5 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 29 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 2 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 8 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro 22 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified in vitro In vitro physical association physical association Fig 3, Fig S1