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    <source releaseDate="2022-02-04">
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        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
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        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
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        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
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    <experimentList>
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        <names>
          <fullName>Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis.</fullName>
        </names>
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          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18083624" refType="primary-reference" refTypeAc="MI:0358"/>
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            <attribute name="publication title" nameAc="MI:1091">Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis.</attribute>
            <attribute name="journal" nameAc="MI:0885">The international journal of biochemistry &amp; cell biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Kim HJ., Kim IS.</attribute>
            <attribute name="remark-internal">I cannot access the Kim, KIm, Han reference for TGFBI, so His -tag location cannot be seen - if there.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
            <attribute name="author-announcement">28-Sep-2020: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
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            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
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        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
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          <names>
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            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
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          <attribute name="author-list" nameAc="MI:0636">Kim HJ., Kim IS.</attribute>
          <attribute name="remark-internal">I cannot access the Kim, KIm, Han reference for TGFBI, so His -tag location cannot be seen - if there.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
          <attribute name="accepted">Accepted 2020-SEP-09 AT 07:10 BST AT 07:10 BST by KALPANAP</attribute>
          <attribute name="journal" nameAc="MI:0885">The international journal of biochemistry &amp; cell biology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
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        <names>
          <fullName>Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis.</fullName>
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            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
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            <attribute name="author-list" nameAc="MI:0636">Kim HJ., Kim IS.</attribute>
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            <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
            <attribute name="author-announcement">28-Sep-2020: Contacted by IntAct-Help.</attribute>
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          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-thp-1</shortLabel>
              <fullName>Homo sapiens acute monocytic leukemia cells</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>thp-1</shortLabel>
                <fullName>Human acute monocytic leukemia cell line</fullName>
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            <shortLabel>anti bait coip</shortLabel>
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        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Kim HJ., Kim IS.</attribute>
          <attribute name="remark-internal">I cannot access the Kim, KIm, Han reference for TGFBI, so His -tag location cannot be seen - if there.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
          <attribute name="accepted">Accepted 2020-SEP-09 AT 07:10 BST AT 07:10 BST by KALPANAP</attribute>
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        <names>
          <fullName>Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis.</fullName>
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            <attribute name="publication title" nameAc="MI:1091">Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis.</attribute>
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            <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
            <attribute name="author-announcement">28-Sep-2020: Contacted by IntAct-Help.</attribute>
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            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
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          </hostOrganism>
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        <interactionDetectionMethod>
          <names>
            <shortLabel>anti tag coip</shortLabel>
            <fullName>anti tag coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag coip</alias>
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          <attribute name="author-list" nameAc="MI:0636">Kim HJ., Kim IS.</attribute>
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          <attribute name="contact-email" nameAc="MI:0634">iskim@knu.ac.kr</attribute>
          <attribute name="accepted">Accepted 2020-SEP-09 AT 07:10 BST AT 07:10 BST by KALPANAP</attribute>
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          <shortLabel>itb2_human</shortLabel>
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          <alias type="gene name synonym" typeAc="MI:0302">CD18</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Complement receptor C3 subunit beta</alias>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014836" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015439" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015812" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016201" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032695" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033760" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036349" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036465" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050730" version="SP_256"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P05107" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JX3" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1L3Y" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YUK" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050839" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JF1" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2P26" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2P28" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2V7D" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K6S" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K71" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K72" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070821" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NEH" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NEN" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071404" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090314" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6R" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6S" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6U" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6V" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6W" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6X" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ES4" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XR1" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ZAZ" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166016" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202733" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-216083" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_256"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000202.3"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001120963.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001290167.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-478N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MLGLRPPLLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVQLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSFVIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRRVECSGRGRCRCNVCECHSGYQLPLCQECPGCPSPCGKYISCAECLKFEKGPFGKNCSAACPGLQLSNNPVKGRTCKERDSEGCWVAYTLEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P05107 original sequence version: 159</attribute>
          <attribute name="crc64">EB9F3C3DF338B4E1</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>bgh3_human</shortLabel>
          <fullName>Transforming growth factor-beta-induced protein ig-h3</fullName>
          <alias type="gene name" typeAc="MI:0301">TGFBI</alias>
          <alias type="gene name synonym" typeAc="MI:0302">BIGH3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Kerato-epithelin</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RGD-containing collagen-associated protein</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q15582" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DQB1" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43218" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43217" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14476" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14472" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43216" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43219" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53XM1" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14471" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000416330" version="SP_211" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10236573" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000349.1"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032954" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036378" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1X3B" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LTB" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LTC" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2VXP" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NV6" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AS7" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7ASC" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7ASG" version="SP_211"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-977225" version="SP_211"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000120708" version="SP_211" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000442011" version="SP_211" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002062" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005201" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005518" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005604" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005802" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007162" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007601" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030198" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031012" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050839" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050840" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050896" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0062023" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000782" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011489" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016666" version="SP_211"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAFSRASQRSVRLAPVYQKLLERMKH</sequence>
        <attributeList>
          <attribute name="crc64">40FDC8A71EBB3D00</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>itam_human</shortLabel>
          <fullName>Integrin alpha-M</fullName>
          <alias type="gene name" typeAc="MI:0301">ITGAM</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CD11B</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CR3A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cell surface glycoprotein MAC-1 subunit alpha</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CR-3 alpha chain</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Leukocyte adhesion receptor MO1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Neutrophil adherence receptor</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CD11 antigen-like family member B</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P11215" version="SP_119" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VAK0" version="SP_119" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VAK2" version="SP_119" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000441691" version="SP_231" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VAK1" version="SP_153" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2568251" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000623.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001139280.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000169896" version="SP_231" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000544665" version="SP_231" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001774" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001851" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006898" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006911" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007229" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008305" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010668" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030900" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031072" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032930" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034688" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035579" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0038024" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043315" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044853" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045963" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070821" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090314" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097242" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098742" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0110090" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0150062" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0150064" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901216" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1904151" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1905114" version="SP_231"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000363" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000413" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002035" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013517" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013519" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013649" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018184" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028994" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032695" version="SP_231"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036465" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A8X" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1BHO" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1BHQ" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1IDN" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1IDO" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JLM" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1M1U" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MF7" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1N9Z" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NA5" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LKE" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LKJ" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3Q3G" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QA3" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4M76" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4XW2" version="SP_231"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RHW" version="SP_231"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166016" version="SP_231"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202733" version="SP_231"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-216083" version="SP_231"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_231"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_231"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSEGGPPGAEPQ</sequence>
        <attributeList>
          <attribute name="crc64">DF77408ED5EE25F9</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="7" imexId="IM-28316-3">
        <names>
          <shortLabel>itgb2-tgfbi-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-25823830" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-28316-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="9">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-25823834" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>his tag</shortLabel>
                    <fullName>his tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">Hexa-His-tag</alias>
                    <alias type="go synonym" typeAc="MI:0303">6-His-tag</alias>
                    <alias type="go synonym" typeAc="MI:0303">Histidine-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">Hexa-His-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">Histidine-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">6-His-tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0521" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456516" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="10">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9606">
                <names>
                  <shortLabel>human-thp-1</shortLabel>
                  <fullName>Homo sapiens acute monocytic leukemia cells</fullName>
                </names>
                <cellType>
                  <names>
                    <shortLabel>thp-1</shortLabel>
                    <fullName>Human acute monocytic leukemia cell line</fullName>
                  </names>
                  <xref>
                    <primaryRef db="cabri" dbAc="MI:0246" id="ACC 16" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="IA:0182" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-8379591" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-904966" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                </cellType>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B, number 3</attribute>
        </attributeList>
      </interaction>
      <interaction id="11" imexId="IM-28316-5">
        <names>
          <shortLabel>itgam-itgb2-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-25823838" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-28316-5" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="12">
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="13">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B, number 2</attribute>
        </attributeList>
      </interaction>
      <interaction id="14" imexId="IM-28316-6">
        <names>
          <shortLabel>tgfbi-itgb2-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-25824749" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-28316-6" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>3</experimentRef>
        </experimentList>
        <participantList>
          <participant id="15">
            <interactorRef>5</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>anti tag western</shortLabel>
                  <fullName>anti tag western blot</fullName>
                  <alias type="synonym" typeAc="MI:1041">anti tag western</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="16">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-25824754" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>his tag</shortLabel>
                    <fullName>his tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">Hexa-His-tag</alias>
                    <alias type="go synonym" typeAc="MI:0303">6-His-tag</alias>
                    <alias type="go synonym" typeAc="MI:0303">Histidine-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">Hexa-His-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">Histidine-tag</alias>
                    <alias type="synonym" typeAc="MI:1041">6-His-tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0521" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456516" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="17">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9606">
                <names>
                  <shortLabel>human-thp-1</shortLabel>
                  <fullName>Homo sapiens acute monocytic leukemia cells</fullName>
                </names>
                <cellType>
                  <names>
                    <shortLabel>thp-1</shortLabel>
                    <fullName>Human acute monocytic leukemia cell line</fullName>
                  </names>
                  <xref>
                    <primaryRef db="cabri" dbAc="MI:0246" id="ACC 16" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="IA:0182" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-8379591" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-904966" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                </cellType>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B, number 1</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>