DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science (New York, N.Y.) 2019 imex curation Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R., Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R. rbanerje@umich.edu 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation ecoli Escherichia coli (strain K12) comigration in sds comigration in sds page comigration in sds predetermined predetermined participant predetermined Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R. rbanerje@umich.edu Accepted 2019-DEC-09 AT 15:03 GMT AT 15:03 GMT by ORCHARD Science (New York, N.Y.) 2019 imex curation Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science (New York, N.Y.) 2019 imex curation Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R., Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R. rbanerje@umich.edu 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ruetz M., Campanello GC., Purchal M., Shen H., McDevitt L., Gouda H., Wakabayashi S., Zhu J., Rubin EJ., Warncke K., Mootha VK., Koutmos M., Banerjee R. rbanerje@umich.edu Accepted 2019-DEC-09 AT 15:03 GMT AT 15:03 GMT by ORCHARD Science (New York, N.Y.) 2019 imex curation a0a045izr3_myctx Methylmalonyl-CoA mutase FPJ45_08210 FPJ47_08210 FPJ48_08195 FPJ49_08220 FPJ50_08200 FPJ51_08195 FPJ53_08210 FPJ54_08220 FPJ55_08220 FPJ58_08220 FPJ60_08225 FPJ61_08210 FPJ62_08200 FPJ63_08195 FPJ64_08210 FPJ65_08195 FPJ66_08200 FPJ67_08235 FPJ69_08235 FPJ70_08235 FPJ71_08235 FPJ72_06990 FPJ73_08200 FPJ76_08160 FPJ77_08210 FPJ78_08215 FPJ79_08225 FPJ80_08215 FPJ81_08225 FPJ82_08230 FPJ83_13395 FPJ84_08205 FPJ85_13385 FPJ86_13375 FPJ87_13380 FPJ88_08170 FPJ89_08210 FPJ90_08190 FPJ91_08215 FPJ92_08190 FPJ93_08210 FPJ94_06980 FPJ95_08205 FPJ96_08220 FPJ97_08220 FPJ98_08190 FPJ99_08240 FPK00_08190 FPK01_08250 FPK02_08190 FPK03_08210 FPK04_08200 FPK05_08205 ERS007663_02000 mutA SAMEA2683035_01025 E5M52_02985 E5M05_03010 ERS013440_02556 FPJ31_08215 FPJ32_08205 FPJ33_08215 FPJ34_08210 FPJ35_08225 FPJ37_08220 FPJ38_08275 FPJ39_08210 FPJ40_08205 FPJ42_08185 FPJ43_08220 FPJ44_08190 FPK06_08195 FPK07_08210 FPK08_08225 FPK09_08220 FPK10_06980 FPK11_08205 FPK12_08175 FPK13_08205 FPK14_08210 FPK16_08195 FPK17_08205 FPK18_08200 FPK19_08225 FPK20_08225 FPK21_08200 FPK22_08210 HRD52_07860 HRD53_07855 protein protein myctx Mycobacterium tuberculosis MSIDVPERADLEQVRGRWRNAVAGVLSKSNRTDSAQLGDHPERLLDTQTADGFAIRALYTAFDELPEPPLPGQWPFVRGGDPLRDVHSGWKVAEAFPANGATADTNAAVLAALGEGVSALLIRVGESGVAPDRLTALLSGVYLNLAPVILDAGADYRPACDVMLALVAQLDPGQRDTLSIDLGADPLTASLRDRPAPPIEEVVAVASRAAGERGLRAITVDGPAFHNLGATAATELAATVAAAVAYLRVLTESGLVVSDALRQISFRLAADDDQFMTLAKMRALRQLWARVAEVVGDPGGGAAVVHAETSLPMMTQRDPWVNMLRCTLAAFGAGVGGADTVLVHPFDVAIPGGFPGTAAGFARRIARNTQLLLLEESHVGRVLDPAGGSWFVEELTDRLARRAWQRFQAIEARGGFVEAHDFLAGQIAECAARRADDIAHRRLAITGVNEYPNLGEPALPPGDPTSPVRRYAAGFEALRDRSDHHLARTGARPRVLLLPLGPLAEHNIRTTFATNLLASGGIEAIDPGTVDAGTVGNAVADAGSPSVAVICGTDARYRDEVADIVQAARAAGVSRVYLAGPEKALGDAAHRPDEFLTAKINVVQALSNLLTRLGA 82D52807A14BDA75 a0a0e8uw09_myctx SAMEA2683035_01024 ERS013440_02555 FPJ30_08210 FPJ31_08220 FPJ32_08210 FPJ33_08220 FPJ34_08215 FPJ35_08230 FPJ36_08205 FPJ37_08225 FPJ38_08280 FPJ39_08215 FPJ40_08210 FPJ41_08210 FPJ42_08190 FPJ43_08225 FPJ44_08195 FPJ45_08215 FPJ46_08205 FPJ47_08215 FPJ48_08200 FPJ49_08225 FPJ50_08205 FPJ51_08200 FPJ52_08220 FPJ53_08215 FPJ54_08225 FPJ55_08225 FPJ56_08205 FPJ57_08200 FPJ58_08225 FPJ59_08210 FPJ60_08230 FPJ61_08215 FPJ62_08205 FPJ63_08200 FPJ64_08215 FPJ65_08200 FPJ66_08205 FPJ67_08240 FPJ69_08240 scpA mutB FPJ70_08240 E5M52_02980 E5M05_03005 FPJ71_08240 FPJ73_08205 FPJ76_08165 FPJ77_08215 FPJ78_08220 FPJ79_08230 FPJ81_08230 FPJ82_08235 FPJ83_13390 FPJ84_08210 FPJ85_13380 FPJ86_13370 FPJ87_13375 FPJ88_08175 FPJ89_08215 FPJ90_08195 FPJ91_08220 FPJ92_08195 FPJ93_08215 FPJ94_06985 FPJ95_08210 FPJ96_08225 FPJ97_08225 FPJ98_08195 FPJ99_08245 FPK00_08195 FPK01_08255 FPK02_08195 FPK03_08215 FPK04_08205 FPK05_08210 FPK06_08200 FPK07_08215 FPK08_08230 FPK09_08225 FPK10_06985 FPK11_08210 FPK12_08180 FPK13_08210 FPK14_08215 FPK16_08200 FPK17_08210 FPK18_08205 FPK21_08205 FPK22_08215 HRD52_07865 HRD53_07860 protein protein myctx Mycobacterium tuberculosis MTTKTPVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAGLNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKYQVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAEQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIDLLHRLAERLGYTLD 9E6B866CE507D022 muta-mutb-7 2 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) 4 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig 2. S10 muta-mutb-8 1 4 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig 2. S10