DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science (New York, N.Y.) 2019 imex curation Zhou L., Sazanov LA. sazanov@ist.ac.at 21-Nov-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation theth Thermus thermophilus 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Zhou L., Sazanov LA. sazanov@ist.ac.at Accepted 2019-OCT-16 AT 12:56 BST AT 12:56 BST by ORCHARD Science (New York, N.Y.) 2019 imex curation vatd_thet8 V-type ATP synthase subunit D atpD vatD V-ATPase subunit D TTHA1271 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MSQVSPTRMNLLQRRGQLRLAQKGVDLLKKKRDALVAEFFGLVREAMEARKALDQAAKEAYAALLLAQAFDGPEVVAGAALGVPPLEGVEAEVENVWGSKVPRLKATFPDGALLSPVGTPAYTLEASRAFRRYAEALIRVANTETRLKKIGEEIKKTTRRVNALEQVVIPGIRAQIRFIQQVLEQREREDTFRLKRIKGKIEAREAEEEGGRPNPQVEIGAGL mint B666AE00DFE0B08B vatf_thet8 V-type ATP synthase subunit F atpF vatF V-ATPase subunit F TTHA1274 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MAVIADPETAQGFRLAGLEGYGASSAEEAQSLLETLVERGGYALVAVDEALLPDPERAVERLMRGRDLPVLLPIAGLKEAFQGHDVEGYMRELVRKTIGFDIKL mint 6679E33E27E102E1 vatb_thet8 V-type ATP synthase beta chain atpB V-ATPase subunit B TTHA1272 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETTGLDLATTSVSLVEDVARLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPANEIAAQIARQATVRPDLSGEGEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALTVAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEGKKGSVTQIPILSMPDDDRTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIGEDALTENDRRYLQFADAFERFFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD mint 43ABBFA6931AAFF3 vatc_thet8 V-type ATP synthase subunit C atpC V-ATPase subunit C TTHA1275 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MADDFAYLNARVRVRRGTLLKESFFQEALDLSFADFLRLLSETVYGGELAGQGLPDVDRAVLRTQAKLVGDLPRLVTGEAREAVRLLLLRNDLHNLQALLRAKATGRPFEEVLLLPGTLREEVWRQAYEAQDPAGMAQVLAVPGHPLARALRAVLRETQDLARVEALLAKRFFEDVAKAAKGLDQPALRDYLALEVDAENLRTAFKLQGSGLAPDAFFLKGGRFVDRVRFARLMEGDYAVLDELSGTPFSGLSGVRDLKALERGLRCVLLKEAKKGVQDPLGVGLVLAYVKEREWEAVRLRLLARRAYFGLPRAQVEEEVVCP 30C7E41C8490CD57 vate_thet8 V-type ATP synthase subunit E atpE V-ATPase subunit E vatE TTHA1276 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MSKLEAILSQEVEAEIQALLQEAEAKAEAVKREAEEKAKALLQARERALEAQYRAALRRAESAGELLVATARTQARGEVLEEVRRRVREALEALPQKPEWPEVVRKLALEALEALPGAKALVANPEDLPHLEALARERGVELQAEPALRLGVRAVGAEGKTQVENSLLARLDRAWDALSSKVAQALWG DIP protein P74901 original sequence version: 62 A6758A3A22200774 q5sit6_thet8 V-type ATP synthase subunit I TTHA1278 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MIAPMEKLVLAGPKGRAKELLQSLQQAGVVHLETLRPEALSAYQLSPEERAELRRWEAVSAGAEHTLSLLGLEAEPARPFPEGLEAAEKALSPIQAHAEGLTRQKQELEEELALAQAYLEPLERLAALAHGLDKSPFLRVIPFLLTEKELPLVEEALRKALEDRYLLAHEAYAGGVAALVVVHRKEVDQAKAALSRAGVAELRLPGALGELPLSEAARRLKERAEAAPRELSEVRQHLAKLARESASTLQSLWTRAQDEVARLKALEELASGRFGFALLGYVPVKAKPKVEEALARHKESVVYAFEPVDEHHEADRIPVVLDNPPWAKPFELLVSFLNTPKYGTFDPTPVVPVFFPFWFGMIVGDIGYALLFYLVGRWLSGYVKRNEPLVIDLFALKLKPQVIGKLVHILNWMVFWTVVWGVIYGEFFGTFLEHLGVFGTPEHPGLIPILIHRIDTAKTANLLILLSVAFGVVLVFFGLALRAYLGLKHRHMAHFWEGVGYLGGLVGVLALAASYLGNLQAGWLQGLMYLGFGVFLLAVLMSRIWLMIPEIFTQAGHILSHIRIYAVGAAGGILAGLLTDVGFALAERLGLLGVLLGLLVAGVLHLLILLLTTLGHMLQPIRLLWVEFFTKFGFYEENGRPYRPFKSVREAQ BC704FC1B08BC73B q5sit7_thet8 TTHA1277 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MKKLLVTVLLAVFGALAFAAEEAAASGGLDRGLIAVGMGLAVGLAALGTGVAQARIGAAGVGAIAEDRSNFGTALIFLLLPETLVIFGLLIAFILNGRL 2B57C14092BA0551 q5sit5_thet8 TTHA1279 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MTGGLVLNAISRAGGAMGGLGLIKSLAEKEKQLLERLEAAKKEAEERVKRAEAEAKALLEEAEAKAKALEAQYRERERAETEALLARYRERAEAEAKAVREKAMARLDEAVALVLKEVLP DIP protein Q5SIT5 original sequence version: 23 FF825EFD697B1C4A vata_thet8 V-type ATP synthase alpha chain atpA V-ATPase subunit A TTHA1273 protein protein thet8 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEAMKEIQGAFKALA mint B22A91ECA7B89970 atpa-atpb-5 1 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 2 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 4 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 10 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 8 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 7 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 5 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 6 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus 9 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified theth Thermus thermophilus physical association physical association Fig 1. Tab S1