DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for dual-mode inhibition of the ABC transporter MsbA. Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature 2018 imex curation Ho H., Miu A., Alexander MK., Garcia NK., Oh A., Zilberleyb I., Reichelt M., Austin CD., Tam C., Shriver S., Hu H., Labadie SS., Liang J., Wang L., Wang J., Lu Y., Purkey HE., Quinn J., Franke Y., Clark K., Beresini MH., Tan MW., Sellers BD., Maurer T., Koehler MFT., Wecksler AT., Kiefer JR., Verma V., Xu Y., Nishiyama M., Payandeh J., Koth CM. payandeh.jian@gene.com 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ho H., Miu A., Alexander MK., Garcia NK., Oh A., Zilberleyb I., Reichelt M., Austin CD., Tam C., Shriver S., Hu H., Labadie SS., Liang J., Wang L., Wang J., Lu Y., Purkey HE., Quinn J., Franke Y., Clark K., Beresini MH., Tan MW., Sellers BD., Maurer T., Koehler MFT., Wecksler AT., Kiefer JR., Verma V., Xu Y., Nishiyama M., Payandeh J., Koth CM. payandeh.jian@gene.com Accepted 2018-JUL-23 AT 13:24 BST AT 13:24 BST by ORCHARD Nature 2018 imex curation msba_eco57 ATP-dependent lipid A-core flippase msbA Lipid A export ATP-binding/permease protein MsbA ECs0997 Z1260 protein protein eco57 Escherichia coli O157:H7 MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ 3D52A3482174A7FE msba-2 1 2 unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig 2, Extended Data Table 1