DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nature structural & molecular biology 2018 imex curation Guenther EL., Ge P., Trinh H., Sawaya MR., Cascio D., Boyer DR., Gonen T., Zhou ZH., Eisenberg DS. david@mbi.ucla.edu 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Guenther EL., Ge P., Trinh H., Sawaya MR., Cascio D., Boyer DR., Gonen T., Zhou ZH., Eisenberg DS. david@mbi.ucla.edu Accepted 2019-NOV-20 AT 08:58 GMT AT 08:58 GMT by ORCHARD Nature structural & molecular biology 2018 imex curation Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nature structural & molecular biology 2018 imex curation Guenther EL., Ge P., Trinh H., Sawaya MR., Cascio D., Boyer DR., Gonen T., Zhou ZH., Eisenberg DS. david@mbi.ucla.edu 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Guenther EL., Ge P., Trinh H., Sawaya MR., Cascio D., Boyer DR., Gonen T., Zhou ZH., Eisenberg DS. david@mbi.ucla.edu Accepted 2019-NOV-20 AT 08:58 GMT AT 08:58 GMT by ORCHARD Nature structural & molecular biology 2018 imex curation tadbp_human TAR DNA-binding protein 43 TARDBP TDP43 protein protein human Homo sapiens Human MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM DIP protein Q13148 original sequence version: 147 DIP protein Q13148 original sequence version: 114 DIP protein Q13148-1 original sequence version: 169 DIP protein Q13148-1 original sequence version: 124 8E09A1206FB4EF4A tardbp-10 1 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified binding region binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified binding region binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction Fig 3, Table 2 tardbp-11 2 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified binding region binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified binding region binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction Fig 2, Table 1