DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators. Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators. Nature structural & molecular biology 2017 imex curation Huang X., Shaffer PL., Ayube S., Bregman H., Chen H., Lehto SG., Luther JA., Matson DJ., McDonough SI., Michelsen K., Plant MH., Schneider S., Simard JR., Teffera Y., Yi S., Zhang M., DiMauro EF., Gingras J. jgingras@amgen.com 04-05-20: Contacted by IntAct-Help. Only protein-protein interactions imex curation human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction experimental particp experimental participant identification experimental particp Huang X., Shaffer PL., Ayube S., Bregman H., Chen H., Lehto SG., Luther JA., Matson DJ., McDonough SI., Michelsen K., Plant MH., Schneider S., Simard JR., Teffera Y., Yi S., Zhang M., DiMauro EF., Gingras J. jgingras@amgen.com Accepted 2020-MAR-16 AT 09:17 GMT AT 09:17 GMT by LUANA Nature structural & molecular biology 2017 imex curation glra3_human Glycine receptor subunit alpha-3 GLRA3 protein protein human Homo sapiens Human MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 8E17A30B3C6E648D glra3-3 1 2 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed purified purified O75311:p.Asn71Gln N71Q mutation mutation certain certain sequence position certain certain certain sequence position certain N Q Tue Jun 30 20:23:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn71Gln' human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. direct interaction direct interaction Table 1, Supplementary Fig 3