UniProt UniProt http://www.uniprot.org Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Biological chemistry 2016 imex curation Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease cbeckerpauly@biochem.uni-kiel.de 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. complementation protein complementation assay PCA complementation tag fluorescence tag visualisation by fluorescence tag fluorescence Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease Both proteins were fused to an RFP monomer and upon interaction, RFP dimerized leading to a 10-fold increase in fluorescence cbeckerpauly@biochem.uni-kiel.de Accepted 2018-DEC-06 AT 11:01 GMT AT 11:01 GMT by PPORRAS Biological chemistry 2016 Only protein-protein interactions imex curation imex curation Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Biological chemistry 2016 imex curation Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease cbeckerpauly@biochem.uni-kiel.de 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast ub reconstruction ubiquitin reconstruction ub reconstruction nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease Where peptide identification had been made to mammalian proteins other than human, these have been mapped to the human ortholog. An identification to yeast KAR1 protein was not remapped. cbeckerpauly@biochem.uni-kiel.de Accepted 2018-DEC-06 AT 11:01 GMT AT 11:01 GMT by PPORRAS Human small intestine cDNA Biological chemistry 2016 Only protein-protein interactions imex curation imex curation Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains. Biological chemistry 2016 imex curation Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease cbeckerpauly@biochem.uni-kiel.de 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. split luciferase complementation split luciferase complementation tag luciferase tag visualisation by luciferase assay tag luciferase Schmidt F., Müller M., Prox J., Arnold P., Schönherr C., Tredup C., Minder P., Ebsen H., Janssen O., Annaert W., Pietrzik C., Schmidt-Arras D., Sterchi EE., Becker-Pauly C. Alzheimers - Interactions investigated in the context of Alzheimers disease cbeckerpauly@biochem.uni-kiel.de Accepted 2018-DEC-06 AT 11:01 GMT AT 11:01 GMT by PPORRAS Biological chemistry 2016 Only protein-protein interactions imex curation imex curation cpne3_human Copine-3 Copine III CPNE3 CPN3 KIAA0636 protein protein human Homo sapiens Human MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ 91F2C5EAD611B842 t4s4_human Transmembrane 4 L6 family member 4 TM4SF4 ILTMP Intestine and liver tetraspan membrane protein protein protein human Homo sapiens Human MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGDGPV mint 402742A2F5F8598F cytm1_human Cysteine-rich and transmembrane domain-containing protein 1 CYSTM1 C5orf32 ORF1-FL49 protein protein human Homo sapiens Human MNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQGGPQEPPKTTVYVVEDQRRDELGPSTCLTACWTALCCCCLWDMLT 93A64A2482B41F5B dma_human HLA class II histocompatibility antigen, DM alpha chain HLA-DMA DMA RING6 MHC class II antigen DMA Really interesting new gene 6 protein protein protein human Homo sapiens Human MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWHDHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD ck024_human Uncharacterized protein C11orf24 C11orf24 Protein DM4E3 FP2568 UNQ1872/PRO4315 protein protein human Homo sapiens Human MWTALVLIWIFSLSLSESHAASNDPRNFVPNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAASSTTVASIAPTTAASSMTAASSTPMTLALPAPTSTSTGRTPSTTATGHPSLSTALAQVPKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPRSSGGTKMPATDSCQPSTQGQYMVVTTEPLTQAVVDKTLLLVVLLLGVTLFITVLVLFALQAYESYKKKDYTQVDYLINGMYADSEM 11C8B0FCC3BBF921 fam3b_human Protein FAM3B FAM3B C21orf11 C21orf76 Cytokine-like protein 2-21 Pancreatic-derived factor PRED44 UNQ320/PRO365 protein protein human Homo sapiens Human MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS 05B74722D03155FF 1a69_human HLA class I histocompatibility antigen, A-69 alpha chain HLA-A Aw-69 HLA class I histocompatibility antigen, A-28 alpha chain HLAA MHC class I antigen A*69 protein protein human Homo sapiens Human MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSLTACKV This interactor won't be updated using Uniprot. 050F1B01157EFDF6 prap1_human Proline-rich acidic protein 1 PRAP1 UPA Uterine-specific proline-rich acidic protein UNQ608/PRO1195 Epididymis tissue protein Li 178 protein protein human Homo sapiens Human MRRLLLVTSLVVVLLWEAGAVPAPKVPIKMQVKHWPSEQDPEKAWGARVVEPPEKDDQLVVLFPVQKPKLLTTEEKPRGQGRGPILPGTKAWMETEDTLGHVLSPEPDHDSLYHPPPEEDQGEERPRLWVMPNHQVLLGPEEDQDHIYHPQ B751EDBFD24D08CA aig1_human Androgen-induced gene 1 protein Fatty acid esters of hydroxy fatty acids hydrolase AIG1 CGI-103 AIG1 protein protein human Homo sapiens Human MALVPCQVLRMAILLSYCSILCNYKAIEMPSHQTYGGSWKFLTFIDLVIQAVFFGICVLTDLSSLLTRGSGNQEQERQLKKLISLRDWMLAVLAFPVGVFVVAVFWIIYAYDREMIYPKLLDNFIPGWLNHGMHTTVLPFILIEMRTSHHQYPSRSSGLTAICTFSVGYILWVCWVHHVTGMWVYPFLEHIGPGARIIFFGSTTILMNFLYLLGEVLNNYIWDTQKSMEEEKEKPKLE DF5D5B8FC41A2C95 ifm1_human Interferon-induced transmembrane protein 1 IFITM1 IFI17 Interferon-inducible protein 9-27 Interferon-induced protein 17 Leu-13 antigen CD225 Dispanin subfamily A member 2a protein protein human Homo sapiens Human MHKEEHEVAVLGPPPSTILPRSTVINIHSETSVPDHVVWSLFNTLFLNWCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIGFILLLVFGSVTVYHIMLQIIQEKRGY 10EE5B64894838ED tm256_human Transmembrane protein 256 TMEM256 C17orf61 protein protein human Homo sapiens Human MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFLHSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAGGTLLLLGWLALAL 3184A3767F5ABB0E sft2b_human Vesicle transport protein SFT2B SFT2D2 SFT2 domain-containing protein 2 UNQ512/PRO1027 protein protein human Homo sapiens Human MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRKGLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWHNKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA F05C57532B7593BD ch044_human Putative uncharacterized protein C8orf44 C8orf44 protein protein human Homo sapiens Human MRKNESYLNQPAPPIPIPTLSLMGGCREHFENHWKGRARWLMPVIPALWEAKAGRSPEVRSSKPAWPTWRNPIFTKNTKISQVLELFLNYQSLICALEKQKRQKGSLAIFCWSFQGGCVSKRPDVPSLKSQKPKRKRITGRKRLSKGFWSLLFSNLGRF 1895B296E4A57F67 s35a3_human UDP-N-acetylglucosamine transporter SLC35A3 Golgi UDP-GlcNAc transporter Solute carrier family 35 member A3 protein protein human Homo sapiens Human MFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQLDSKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA 69DFD944E37206C8 at5g3_human ATP synthase F(0) complex subunit C3, mitochondrial ATP5MC3 ATP synthase lipid-binding protein ATP synthase membrane subunit c locus 3 ATP synthase proteolipid P3 ATP synthase proton-transporting mitochondrial F(0) complex subunit C3 ATP5G3 ATPase protein 9 ATPase subunit c protein protein human Homo sapiens Human MFACAKLACTPSLIRAGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM 19EC0D1710A0AA3F tsn8_human Tetraspanin-8 TSPAN8 TM4SF3 Transmembrane 4 superfamily member 3 Tumor-associated antigen CO-029 protein protein human Homo sapiens Human MAGVSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQSYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGNK D1058F054EE8C14E apoc3_human Apolipoprotein C-III APOC3 Apolipoprotein C3 protein protein human Homo sapiens Human MQPRVLLVVALLALLASARASEAEDASLLSFMQGYMKHATKTAKDALSSVQESQVAQQARGWVTDGFSSLKDYWSTVKDKFSEFWDLDPEVRPTSAVAA D4E806339FAE4DA7 rnk_human Ribonuclease kappa RNASEK protein protein human Homo sapiens Human MGWLRPGPRPLCPPARASWAFSHRFPSPLAPRRSPTPFFMASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENGPQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR chpt1_human Cholinephosphotransferase 1 CHPT1 AAPT1-like protein CPT1 Diacylglycerol cholinephosphotransferase 1 MSTP022 protein protein human Homo sapiens Human MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD AE5357C02ED40E4C tmm11_human Transmembrane protein 11, mitochondrial TMEM11 C17orf35 PM1 Protein PM1 Protein PMI protein protein human Homo sapiens Human MAAWGRRRLGPGSSGGSARERVSLSATDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV FE46BACEBF5ACD1D vkor1_human Vitamin K epoxide reductase complex subunit 1 VKORC1 VKOR Vitamin K1 2,3-epoxide reductase subunit 1 MSTP134 MSTP576 UNQ308/PRO351 protein protein human Homo sapiens Human MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH 2F00526A6C561D5A sim24_human Small integral membrane protein 24 C19orf77 HSPC323 SMIM24 protein protein human Homo sapiens Human METLGALLVLEFLLLSPVEAQQATEHRLKPWLVGLAAVVGFLFIVYLVLLANRLWCSKARAEDEEETTFRMESNLYQDQSEDKREKKEAKEKEEKRKKEKKTAKEGESNLGLDLEEKEPGDHERAKSTVM 678E332E2A13BCC7 spit2_human Kunitz-type protease inhibitor 2 SPINT2 HAI2 KOP Placental bikunin Hepatocyte growth factor activator inhibitor type 2 protein protein human Homo sapiens Human MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL mint Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa A7D3360C0EECAB2B t4s20_human Transmembrane 4 L6 family member 20 TM4SF20 UNQ518/PRO994 protein protein human Homo sapiens Human MTCCEGWTSCNGFSLLVLLLLGVVLNAIPLIVSLVEEDQFSQNPISCFEWWFPGIIGAGLMAIPATTMSLTARKRACCNNRTGMFLSSLFSVITVIGALYCMLISIQALLKGPLMCNSPSNSNANCEFSLKNISDIHPESFNLQWFFNDSCAPPTGFNKPTSNDTMASGWRASSFHFDSEENKHRLIHFSVFLGLLLVGILEVLFGLSQIVIGFLGCLCGVSKRRSQIV 1718E0594997A1A1 ssrg_human Translocon-associated protein subunit gamma Signal sequence receptor subunit gamma SSR3 TRAPG protein protein human Homo sapiens Human MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK DEE0B14BF524F62A mep1b_human Meprin A subunit beta MEP1B Endopeptidase-2 N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta PABA peptide hydrolase PPH beta Meprin B protein protein human Homo sapiens Human MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQIRNSIIGEKYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCGMIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKEIPTGSWQLYHVTLKVTKKFRVVFEGRKGSGASLGGLSIDDINLSETRCPHHIWHIRNFTQFIGSPNGTLYSPPFYSSKGYAFQIYLNLAHVTNAGIYFHLISGANDDQLQWPCPWQQATMTLLDQNPDIRQRMSNQRSITTDPFMTTDNGNYFWDRPSKVGTVALFSNGTQFRRGGGYGTSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQIQLTPAPSVQDLCSKTTCKNDGVCTVRDGKAECRCQSGEDWWYMGERCEKRGSTRDTIVIAVSSTVAVFALMLIITLVSVYCTRKKYRERMSSNRPNLTPQNQHAF DIP protein Q16820 original sequence version: 124 4733DBF018A4F3CD il32_human Interleukin-32 IL32 NK4 TAIF Natural killer cells protein 4 Tumor necrosis factor alpha-inducing factor protein protein human Homo sapiens Human MCFPKVLSDDMKKLKARMVMLLPTSAQGLGAWVSACDTEDTVGHLGPWRDKDPALWCQLCLSSQHQAIERFYDKMQNAESGRGQVMSSLAELEDDFKEGYLETVAAYYEEQHPELTPLLEKERDGLRCRGNRSPVPDVEDPATEEPGESFCDKVMRWFQAMLQRLQTWWHGVLAWVKEKVVALVHAVQALWKQFQSFCCSLSELFMSSFQSYGAPRGDKEELTPQKCSEPQSSK 5F339FE2D348A761 nkg7_human Protein NKG7 NKG7 GIG1 G-CSF-induced gene 1 protein Granule membrane protein of 17 kDa Natural killer cell protein 7 p15-TIA-1 protein protein human Homo sapiens Human MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGYIHVTQTFSIMAVLWALVSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL CEE2901B6DC42A8C uty_human Histone demethylase UTY UTY KDM6C Ubiquitously-transcribed TPR protein on the Y chromosome Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein [histone H3]-trimethyl-L-lysine(27) demethylase UTY protein protein human Homo sapiens Human MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLSSSS DIP protein O14607 original sequence version: 92 DIP protein O14607 original sequence version: 93 D83B8CAB861BCE60 reep5_human Receptor expression-enhancing protein 5 REEP5 C5orf18 DP1 TB2 Polyposis locus protein 1 Protein TB2 protein protein human Homo sapiens Human MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST F4E57E500CB7C831 cc167_human Coiled-coil domain-containing protein 167 CCDC167 C6orf129 HSPC265 protein protein human Homo sapiens Human MTKKKRENLGVALEIDGLEEKLSQCRRDLEAVNSRLHSRELSPEARRSLEKEKNSLMNKASNYEKELKFLRQENRKNMLLSVAIFILLTLVYAYWTM 8B68E89EFEEB782C arl14_human ADP-ribosylation factor-like protein 14 ARL14 ARF7 ADP-ribosylation factor 7 protein protein human Homo sapiens Human MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN DAA099214D8400DF aqp7_human Aquaporin-7 AQP7 AQP7L AQP9 Aquaglyceroporin-7 Aquaporin adipose Aquaporin-7-like protein protein human Homo sapiens Human MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF 8A05F92B977D2F93 obrg_human Leptin receptor gene-related protein LEPROT LEPR OBR Endospanin-1 Leptin receptor overlapping transcript protein OB-R gene-related protein protein protein human Homo sapiens Human MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLIFGRGDDFSWEQW DIP protein O15243 original sequence version: 59 pdz1i_human PDZK1-interacting protein 1 MAP17 PDZK1IP1 17 kDa membrane-associated protein Protein DD96 protein protein human Homo sapiens Human MSALSLLILGLLTAVPPASCQQGLGNLQPWMQGLIAVAVFLVLVAIAFAVNHFWCQEEPEPAHMILTVGNKADGVLVGTDGRYSSMAASFRSSEHENAYENVPEEEGKVRSTPM 7DEB64C3AF78CB18 rtn4_human Reticulon-4 Neurite outgrowth inhibitor Foocen Neuroendocrine-specific protein Neuroendocrine-specific protein C homolog RTN-x Reticulon-5 RTN4 KIAA0886 NOGO My043 SP1507 protein protein human Homo sapiens Human MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE CDE239BBF31589CA t4s5_human Transmembrane 4 L6 family member 5 TM4SF5 Tetraspan transmembrane protein L6H protein protein human Homo sapiens Human MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH selk_human Selenoprotein K SELENOK SELK HSPC030 HSPC297 protein protein human Homo sapiens Human MVYISNGQVLDSRSQSPWRLSLITDFFWGIAEFVVLFFKTLLQQDVKKRRSYGNSSDSRYDDGRGPPGNPPRRMGRINHLRGPSPPPMAGGUGR D26F13E90BEC6807 mep1b-arl14-1 2 35 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-aig1-1 2 12 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-apoc3-1 2 20 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-aqp7-1 2 36 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-atp5mc3-1 2 18 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-chpt1-1 2 22 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-cpne3-1 2 4 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-uty-1 2 32 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-hla_a-1 2 10 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-hla_dma-1 2 7 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-ifitm1-1 2 13 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-il32-1 2 30 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-spint2-1 2 26 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-leprot-1 2 37 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-pdzk1ip1-1 2 38 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-prap1-1 2 11 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-fam3b-1 2 9 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-nkg7-1 2 31 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-c8orf44-1 2 16 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-reep5-1 2 33 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-rtn4-1 2 39 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-rnasek-1 2 21 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-selenok-1 2 41 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tspan8-1 2 19 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1, Fig. 1A mep1b-ssr3-1 2 28 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tm4sf20-1 2 27 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tm4sf4-1 2 5 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tm4sf5-1 2 40 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-ccdc167-1 2 34 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tmem11-1 2 23 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-smim24-1 2 25 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-slc35a3-1 2 17 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-c11orf24-1 2 8 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tmem256-1 2 14 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tspan8-2 3 19 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-n luciferase-n luciferase-n c-term range C-terminal range c-term range c-term range C-terminal range c-term range 29 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-c luciferase-c luciferase-c c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig. 1B To confirm the protein-protein interaction between meprin β and TSPAN8 in mammalian cells we performed a luciferase-based protein complementation assay (Cassonnet et al., 2011). mep1b-mep1b-1 3 29 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-n luciferase-n luciferase-n c-term range C-terminal range c-term range c-term range C-terminal range c-term range 29 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-c luciferase-c luciferase-c c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig. 1B To confirm the protein-protein interaction between meprin β and TSPAN8 in mammalian cells we performed a luciferase-based protein complementation assay (Cassonnet et al., 2011). tspan8-tspan8-1 3 19 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-n luciferase-n luciferase-n c-term range C-terminal range c-term range c-term range C-terminal range c-term range 19 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-c luciferase-c luciferase-c c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig. 1B To confirm the protein-protein interaction between meprin β and TSPAN8 in mammalian cells we performed a luciferase-based protein complementation assay (Cassonnet et al., 2011). mep1b-tspan8-3 1 19 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal rfp tag red fluorescent protein tag red fluorescent protein RFP red fluorescent protein RFP rfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 29 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal rfp tag red fluorescent protein tag red fluorescent protein RFP red fluorescent protein RFP rfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig. 1C To confirm the protein-protein interaction between meprin β and TSPAN8 in mammalian cells we performed a luciferase-based protein complementation assay (Cassonnet et al., 2011). mep1b-cystm1-1 2 6 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-sft2d2-1 2 15 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-vkorc1-1 2 24 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed n-terminal nubg nubg n-term range n-terminal range n-term range n-term range n-terminal range n-term range 29 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed c-terminal cub cub c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Supp. Table 1 mep1b-tspan8-4 3 19 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-c luciferase-c luciferase-c c-term range C-terminal range c-term range c-term range C-terminal range c-term range 29 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c-terminal luciferase-n luciferase-n luciferase-n c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig. 1B To confirm the protein-protein interaction between meprin β and TSPAN8 in mammalian cells we performed a luciferase-based protein complementation assay (Cassonnet et al., 2011).