DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266579X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266580X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266578X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266582X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266583X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266584X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology 2014 imex curation Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang S., Jiang B., Zhang T., Liu L., Wang Y., Wang Y., Chen X., Lin H., Zhou L., Xia Y., Chen L., Yang C., Xiong Y., Ye D., Guan KL. DIP original experiment: DIP-266581X PLoS biology 2014 IMEx Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. elp3_human Elongator complex protein 3 ELP3 Protein lysine acetyltransferase ELP3 tRNA uridine(34) acetyltransferase protein protein human Homo sapiens Human MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK DIP protein Q9H9T3 original sequence version: 124 DIP protein Q9H9T3 original sequence version: 127 60898ADD3DBAD035 hdac3_mouse Histone deacetylase 3 Hdac3 protein protein mouse Mus musculus Mouse MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVISQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKES DIP protein O88895 original sequence version: 74 DIP protein O88895 original sequence version: 89 DIP protein O88895 original sequence version: 92 DIP protein O88895 original sequence version: 104 DIP protein O88895 original sequence version: 138 DIP protein O88895 original sequence version: 135 DIP protein O88895 original sequence version: 105 DIP protein O88895 original sequence version: 111 B0C3BB2C5CD95E0E hdac3_human Histone deacetylase 3 HDAC3 RPD3-2 SMAP45 protein protein human Homo sapiens Human MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI DIP protein O15379 original sequence version: 159 DIP protein O15379 original sequence version: 161 DIP protein O15379 original sequence version: 162 DIP protein O15379 original sequence version: 89 DIP protein O15379 original sequence version: 156 DIP protein O15379 original sequence version: 176 DIP protein O15379 original sequence version: 170 DIP protein O15379-1 original sequence version: 170 DIP protein O15379 original sequence version: 127 DIP protein O15379-1 original sequence version: 128 DIP protein O15379 original sequence version: 119 94485C1EBDCF5AD0 pgk1_human Phosphoglycerate kinase 1 Primer recognition protein 2 Cell migration-inducing gene 10 protein PGK1 PGKA OK/SW-cl.110 MIG10 protein protein human Homo sapiens Human MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI DIP protein P00558 original sequence version: 181 B5DFC7B5FA01767C pgk1_mouse Phosphoglycerate kinase 1 Pgk1 Pgk-1 protein protein mouse Mus musculus Mouse MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV DIP protein P09411 original sequence version: 143 5E2EE194FF9D8CEE p00558-1 Phosphoglycerate kinase 1 PGK1 PGKA Cell migration-inducing gene 10 protein Primer recognition protein 2 MIG10 OK/SW-cl.110 protein protein human Homo sapiens Human MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI DIP protein P00558-1 original sequence version: 181 pgk1-hdac3-1 2 11 unspecified role unspecified role bait bait human Homo sapiens Human 10 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association pgk1-hdac3-2 3 10 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 13 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association pgk1-elp3-1 5 8 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 13 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association pgk1-hdac3-3 7 9 unspecified role unspecified role prey prey mouse Mus musculus Mouse 12 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association pgk1-hdac3-4 1 10 unspecified role unspecified role prey prey GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 13 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli direct interaction direct interaction hdac3-pgk1-1 6 11 unspecified role unspecified role prey prey human Homo sapiens Human 10 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range O15379:p.Ser424Ala S424A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S424A'. Wed May 02 20:16:36 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser424ala' Tue Jun 30 19:57:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser424Ala' human Homo sapiens Human physical association physical association hdac3-pgk1-2 4 10 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range O15379:p.Ser424Ala S424A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S424A'. Wed May 02 14:31:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser424ala' Tue Jun 30 18:04:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser424Ala' human Homo sapiens Human 13 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association