DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu The PTEN Tumor Suppressor Forms Homodimers in Solution. The PTEN Tumor Suppressor Forms Homodimers in Solution. Structure (London, England : 1993) 2015 imex curation Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. DIP original experiment: DIP-267273X Structure (London, England : 1993) 2015 IMEx The PTEN Tumor Suppressor Forms Homodimers in Solution. The PTEN Tumor Suppressor Forms Homodimers in Solution. The PTEN Tumor Suppressor Forms Homodimers in Solution. Structure (London, England : 1993) 2015 imex curation Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. DIP original experiment: DIP-267274X Structure (London, England : 1993) 2015 IMEx The PTEN Tumor Suppressor Forms Homodimers in Solution. The PTEN Tumor Suppressor Forms Homodimers in Solution. The PTEN Tumor Suppressor Forms Homodimers in Solution. Structure (London, England : 1993) 2015 imex curation Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. Only protein-protein interactions in vitro In vitro saxs x ray scattering saxs predetermined predetermined participant predetermined Heinrich F., Chakravarthy S., Nanda H., Papa A., Pandolfi PP., Ross AH., Harishchandra RK., Gericke A., Lösche M. DIP original experiment: DIP-267275X Structure (London, England : 1993) 2015 IMEx The PTEN Tumor Suppressor Forms Homodimers in Solution. p60484-1 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN MMAC1 TEP1 55kDa Mutated in multiple advanced cancers 1 Phosphatase and tensin homolog protein protein human Homo sapiens Human MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV DIP protein P60484-1 original sequence version: 148 DIP protein P60484 original sequence version: 113 DIP protein P60484 original sequence version: 119 DIP protein P60484-1 original sequence version: 147 DIP protein P60484 original sequence version: 147 pten-pten-5 1 4 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range ecolx Escherichia coli 4 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction pten-9 2 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction pten-2 3 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction