DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 2015 imex curation Perera RM., Stoykova S., Nicolay BN., Ross KN., Fitamant J., Boukhali M., Lengrand J., Deshpande V., Selig MK., Ferrone CR., Settleman J., Stephanopoulos G., Dyson NJ., Zoncu R., Ramaswamy S., Haas W., Bardeesy N. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Perera RM., Stoykova S., Nicolay BN., Ross KN., Fitamant J., Boukhali M., Lengrand J., Deshpande V., Selig MK., Ferrone CR., Settleman J., Stephanopoulos G., Dyson NJ., Zoncu R., Ramaswamy S., Haas W., Bardeesy N. DIP original experiment: DIP-265957X Nature 2015 IMEx Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 2015 imex curation Perera RM., Stoykova S., Nicolay BN., Ross KN., Fitamant J., Boukhali M., Lengrand J., Deshpande V., Selig MK., Ferrone CR., Settleman J., Stephanopoulos G., Dyson NJ., Zoncu R., Ramaswamy S., Haas W., Bardeesy N. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip ms participant Identification by mass spectrometry ms participant Perera RM., Stoykova S., Nicolay BN., Ross KN., Fitamant J., Boukhali M., Lengrand J., Deshpande V., Selig MK., Ferrone CR., Settleman J., Stephanopoulos G., Dyson NJ., Zoncu R., Ramaswamy S., Haas W., Bardeesy N. DIP original experiment: DIP-265958X Nature 2015 IMEx Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. tfe3_human Transcription factor E3 TFE3 BHLHE33 Class E basic helix-loop-helix protein 33 protein protein human Homo sapiens Human MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES DIP protein P19532 original sequence version: 167 EF1F11AB624C6BE1 ipo8_human Importin-8 IPO8 RANBP8 Ran-binding protein 8 protein protein human Homo sapiens Human MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN DIP protein O15397 original sequence version: 125 3D7195FD57D7D9AF tfe3-ipo8-1 1 4 unspecified role unspecified role prey prey human Homo sapiens Human 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association tfe3-ipo8-2 2 4 unspecified role unspecified role prey prey human Homo sapiens Human 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association