DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Nature 2015 imex curation Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. Only protein-protein interactions drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. DIP original experiment: DIP-267913X Nature 2015 IMEx Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Nature 2015 imex curation Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. Only protein-protein interactions drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. DIP original experiment: DIP-267911X Nature 2015 IMEx Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Nature 2015 imex curation Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. Only protein-protein interactions drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. DIP original experiment: DIP-267912X Nature 2015 IMEx Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Two insulin receptors determine alternative wing morphs in planthoppers. Nature 2015 imex curation Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. Only protein-protein interactions drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xu HJ., Xue J., Lu B., Zhang XC., Zhuo JC., He SF., Ma XF., Jiang YQ., Fan HW., Xu JY., Ye YX., Pan PL., Li Q., Bao YY., Nijhout HF., Zhang CX. DIP original experiment: DIP-267910X Nature 2015 IMEx Two insulin receptors determine alternative wing morphs in planthoppers. a0a0c4ur07_nillu Tyrosine-protein kinase receptor protein protein nillu Nilaparvata lugens Brown planthopper MFCRSRKKWGLLAGVRLTSVTVISTVIFILTCYETVSGRICPNTDVRNNISIMRTKLENCTVIEGSLHVVLIEKASENKFENVSFPLLREVTGFVLFYRVNYLRSIGQLFPNLSVIRGNHLFMNFALVIYEMRDLQEVGLYNLRTIVRGSVCIFKNTKLCYVNSVDWLSLSEMGWWIEHNKSPELCGRCPANCKHCWNAKRCQLTQQGDGAQLSDTGATVAGQLPEKCHPLCLGGCYGPSAHECVACRGVFTPDNMCVRQCPPGTVKWLERRCIYTETCQNHTTADPNIIKNNNDTNFFVFNGSCVHECPEGLEKGPNGCRQCTSSHCRKTCEGQVVDSLSAAQNLTGCTHIVGSLIISLKTGSDKFIQPELQQSLGSIQEIDGSLKIVRTFPLVSLNFLRNLRIIHGKKLLFNDNKSFVVAENHNLQELWDWNQRPSRLQILNGSVFFHYNPKLCLSLIKSFIKEINFTKTIGLLDISEESNGDKFPCKTVNLNVRVLKRYNESVELYIEKPKDKEMFSRYILYYVKSPFQNISYEEPDDCGDYGWKTKDISSDWKLDEPHNITYPITQLEPNTQYAFYVKTYTIDSFALKSGVQYFRTLPSKPTFPTKLTATSESSSSITLKWNPPSIANGKLEKYIVHGYKQKMDMAFYLNRDFCIYPLQYREVVITTPTVLPEVNQTTEFNETAISKYKDNSEKCVCEEKVKVEAIKSKQTHDNDDLQMFCDNSRSYKYLPNRALDIDKGFECEKSFFAALYERPFGNEGMRYNYNNIDIQGSSQSNADQKSINTQDNETHDRNIGIVDQLSEADEFVIDDNGQIARFFLHIPGNMTETKVENLPYFSEYTIEVRACREIDSEEPLESRSLASRCSFSSITTHRTQQNKTADFIPFVKHKIFNKTTAMFRWGKPANPNGIIVSYSFEYRSIDRSSSLHQTICVSIEEYNNNSKKGYNYKLENIPRGKYAYRIRALSMASEGEYTESSYFEIEEEFSFSFKLIFAVCFIMMTVFMIICSLYYWRKKPVVMFPDVNPEYQSIYNCRYVEDEWELCRENVEIVKELGKGTFGMVYEGILKPNNVPCAIKTVSARQNESEYFDFLLEASIMKSFSGSNHIIRLLGVVSRGTPPLVVMELMALGDLKMFLRSTRDSSLRPPPTGRTVLHMAAQIADGMAYLESKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPIRWMAPESCYDGIFSSHSDVWSYGVVLWEISTLAEQPYQGKSNEEVLAYVLAGNSLQAPLFCPEVIKPIMLSCWNFRPTKRPSFLQIVNTLEPHTNDYFKTVSFFHSTEAIELRKNLKMYDYHNLNKMLLLSTLLNNEDTNEANSSSSHDSPSSSHSNLNNGSQHNYCIDDKDDNYVTGTNSPAVITENNDCSKNRRVLTNGQAHLTR DIP protein A0A0C4UR07 original sequence version: 10 a0a0c4uqs4_nillu Tyrosine-protein kinase receptor protein protein nillu Nilaparvata lugens Brown planthopper MEDSACPGCSLRPTNVGRRTRRGGGGLRGGYGDDVSWGVVSVLAAVCCLLLCLANPVEAFASLGTELRPRVDLSTDRSSPDARGVCQSLDIRNAAREFHQLQGCQVVEGFVQIVLMDKAVESEFANFSFPELREITGYLLLYRIDGLRTLSNLFPNLAVIRGNTLFFNYALVVFEMLHLQEMGLKSLTDIVRGAVHISKNPMLCYVDTIDWDKIARSSQGGHFITGNKKKNECPICQTNAVCPTSATNDNLCWNIQHCQKFCSKCEEGTACMDDGTCCDKNCLGGCNGTGPTNCIACRGYLFQGTCVATCPVQTYQYLQRRCVLEKECYDMPKPREIMSEEVRPQPWKPFMNQCLIDCPPNYAEAPIDNFRGLDPDRTYYRCEPCKGPCKKECEGLNVDSISSSQRLRGCTYIKGSLEIQIRGGYNVVKELENNLNMIEEINGYLKIVRSFPLVSLNFLKKLKVIHGEKLESGKYALVVLDNQNLVELWDFGPSREERLRITRGKLFFHFNPKLCYFKIDNLRKYLGMPEFTDNEVARNSNGDKVACNISLLDARVETRSSKGVIIKWKEFEHYDPRTLLGYIIYFIEAPYQNISLYDGRDACGGDGWRVIDVSPLEKDNETTTLNEDKNKTKHMSQLITQLKPYTQYAFYVKTYTIASENSGAQSPIIYFRTEPDIPSMPQNLVAKIESSSEIKVAWQPPLNPNGNVTHYLITAKWERDDSEFLAQRNYCEEPLTSIVDVTNQAGKWTLVNDDDVYTGGKPDDCVCMDDKKVNKKKQQEKEIQFQIQFEDTLQNLVYIKRSSLRDKREISLRDGKTITENHFAESDIRMKTVPVSTDLEVQRLENEPQVKILLQGKTSYVIRGLHHFAQYTISVSACRQRDETDKLIMTNNCSTHSIISARTKKLANADVVSEIWHEVIENPVNHTQPIVKLYWKEPPAPNGLIVMYQISHWLVFENQQHKKTHCISRRQFLEEGNSHTLTNLAPGNYSYQVCATSLAGLANCSQSPLRYFEIQGYSSVTSLQIIFATFMTAGMLILLGFVVFLRNKSNKQTPLIAECNPEYVSTVYVPDDWEVPRSQIELDGELGQGSFGMVYEGIATNVVPGEPRKKCAIKTVNENASLRERVEFLNEASVMKASNTHHVVRLIGVVSQGQPPYVVMELMANGDLKSYLRLHRPDATVEPHKQPPTLKRIRQMAIEIADGMAYLAAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMSPESLKDGVFTSSSDVWSYGVVIWEMATLASQPYQGLSNEQVLNYVKTGGCMERPDNCPDVLYNLMRQCWQHKPADRPTFMQLVRCLLPFAHPSFASLSFYHSDEGGQERRASTSTPQATVEEETPLRVTRDVEDFSLSDDEDDYEPHLPAPAPAPATDTKVSNGSATAPTPNGFIRRPPAANGNSVNVKTTKC DIP protein A0A0C4UQS4 original sequence version: 10 a0a0c4uqs4_nillu-a0a0c4uqs4_nillu-1 3 6 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly 6 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association a0a0c4uqs4_nillu-a0a0c4ur07_nillu-1 4 5 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly 6 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association a0a0c4uqs4_nillu-a0a0c4uqs4_nillu-2 1 6 unspecified role unspecified role bait bait V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly 6 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association a0a0c4ur07_nillu-a0a0c4uqs4_nillu-1 2 5 unspecified role unspecified role bait bait V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly 6 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association