DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nature cell biology 2015 imex curation Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. DIP original experiment: DIP-266154X Nature cell biology 2015 IMEx Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nature cell biology 2015 imex curation Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. Only protein-protein interactions human Homo sapiens Human pull down pull down predetermined predetermined participant predetermined Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. DIP original experiment: DIP-266155X Nature cell biology 2015 IMEx Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nature cell biology 2015 imex curation Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Dulloo I., Phang BH., Othman R., Tan SY., Vijayaraghavan A., Goh LK., Martin-Lopez M., Marques MM., Li CW., Wang de Y., Marín MC., Xian W., McKeon F., Sabapathy K. DIP original experiment: DIP-266156X Nature cell biology 2015 IMEx Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG o15350-2 Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP DIP protein O15350-2 original sequence version: 165 DIP protein O15350-2 original sequence version: 135 DIP protein O15350-2 original sequence version: 174 Produced by alternative splicing of isoform Alpha. 0FDC0546E29D683E siah1_human E3 ubiquitin-protein ligase SIAH1 Seven in absentia homolog 1 Siah-1a SIAH1 HUMSIAH RING-type E3 ubiquitin transferase SIAH1 protein protein human Homo sapiens Human MSRQTATALPTGTSKCPPSQRVPALTGTTASNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC DIP protein Q8IUQ4 original sequence version: 132 FA0698D0DC1B0A15 p73_human Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH DIP protein O15350 original sequence version: 170 DIP protein O15350-1 original sequence version: 100 DIP protein O15350 original sequence version: 123 DIP protein O15350 original sequence version: 149 DIP protein O15350-1 original sequence version: 165 DIP protein O15350 original sequence version: 92 DIP protein O15350-1 original sequence version: 122 DIP protein O15350-1 original sequence version: 135 DIP protein O15350-1 original sequence version: 174 A467493C5D93EEE0 tp73-ub-6 1 4 unspecified role unspecified role prey prey human Homo sapiens Human 5 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association ub-tp73-1 2 4 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal human Homo sapiens Human 5 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association tp73-siah1-1 3 6 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 7 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association