DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu NMDA receptor structures reveal subunit arrangement and pore architecture. NMDA receptor structures reveal subunit arrangement and pore architecture. Nature 2014 imex curation Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. Only protein-protein interactions human Homo sapiens Human pull down pull down predetermined predetermined participant predetermined Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. DIP original experiment: DIP-262092X Nature 2014 IMEx NMDA receptor structures reveal subunit arrangement and pore architecture. NMDA receptor structures reveal subunit arrangement and pore architecture. NMDA receptor structures reveal subunit arrangement and pore architecture. Nature 2014 imex curation Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. DIP original experiment: DIP-262094X Nature 2014 IMEx NMDA receptor structures reveal subunit arrangement and pore architecture. NMDA receptor structures reveal subunit arrangement and pore architecture. NMDA receptor structures reveal subunit arrangement and pore architecture. Nature 2014 imex curation Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. Only protein-protein interactions human Homo sapiens Human molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Lee CH., Lü W., Michel JC., Goehring A., Du J., Song X., Gouaux E. DIP original experiment: DIP-262093X Nature 2014 IMEx NMDA receptor structures reveal subunit arrangement and pore architecture. nmdz1_xenla Glutamate receptor ionotropic, NMDA 1 N-methyl-D-aspartate receptor subunit NR1 grin1 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MGTMRLFLLAVLFLFSFARAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKASFRSITSTLASSFKRRRSSKDTVNVVV DIP protein Q91977 original sequence version: 65 DIP protein Q91977 original sequence version: 105 E2612938C9125D76 nmde2_xenla Glutamate receptor ionotropic, NMDA 2B N-methyl D-aspartate receptor subtype 2B grin2b protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MRPTEACCYLKISLIILFYMGCYAQKHPNMDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVALVTMNESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDTVPDEFPTGLISVSYDEWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRVYEAHMLKRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMKYYVWPVFDLYPNSEEHKDEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFFWQLRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEDRQSALDSPSATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSFQPEENLFSDYISEVERTFGNLQLKDSNVYQDHFHHHRPHSIGSNSSIDGLYDCDNAPFTTQPRSLSKKPLDIGLPSKHPSPQIGDLYGKFSFKSDHYGAPDDLIRSDVSDISTHTVTYGNIEGNAKRRKQYKDSLKKRPASAKSRREFDEIELAYRRRQRSPDHKRYFRDKEGLRDFYLDQFRTKENNPHWEHVDLTHIYAERADDFKHDTSCSNRQHQKHVGEFVQTDRKHGSGGNAWEKNMSNIEWEDRASSNFCRNCPSKMHNYTGQNTNRPACIRCEVCKKAGNLYDISEDNSLQDLEARPIQAPNSKYPQSPNGKAQKRNRSKLHRQHSYDTFVDLQKEDVTLAPRSVSLKDKERFLDGSPYAHMFEMPNETSFTSKSHGPTHNPGGYMLSRSLYPDRVTQNPFIPTFGDDQCLLHGSKPYYFRQPAIGGLKGRADFRGAGKSLSAQHSGPSGHFQKDICIGNQPNACVSNNKNPRSFNNSTNGHVYEKLSSIESDV DIP protein A7XY94 original sequence version: 32 nr2b-c0kd15_xenla-1 1 5 unspecified role unspecified role bait bait Region 1-839 Region 1-839 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain StrepII-tag StrepII-tag strep ii tag strep ii tag Strep (II) Strep II Strep (II) Strep II c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 4 unspecified role unspecified role prey prey Region 1-834 Region 1-834 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association c0kd15_xenla-nr2b-1 2 5 unspecified role unspecified role unspecified role unspecified role Region 1-839 Region 1-839 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 4 unspecified role unspecified role unspecified role unspecified role Region 1-834 Region 1-834 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction c0kd15_xenla-nr2b-2 3 5 unspecified role unspecified role unspecified role unspecified role Region 1-839 Region 1-839 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 4 unspecified role unspecified role unspecified role unspecified role Region 1-834 Region 1-834 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction