DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nature cell biology 2014 imex curation Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. DIP original experiment: DIP-260065X Nature cell biology 2014 IMEx Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nature cell biology 2014 imex curation Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. DIP original experiment: DIP-260063X Nature cell biology 2014 IMEx Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nature cell biology 2014 imex curation Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Cai Z., Jitkaew S., Zhao J., Chiang HC., Choksi S., Liu J., Ward Y., Wu LG., Liu ZG. DIP original experiment: DIP-260064X Nature cell biology 2014 IMEx Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. ripk3_human Receptor-interacting serine/threonine-protein kinase 3 RIPK3 RIP3 RIP-like protein kinase 3 Receptor-interacting protein 3 protein protein human Homo sapiens Human MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLSQLRSSNRRFSIPESGQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSSVPKKCPSLTKRSRAQEEQVPQAWTAGTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPGPRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLAPSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK DIP protein Q9Y572 original sequence version: 134 BF755F8A0B1810A1 q8nb16-1 Mixed lineage kinase domain-like protein MLKL protein protein human Homo sapiens Human MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTTAMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQRMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYLPPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK DIP protein Q8NB16-1 original sequence version: 99 ripk3-mlkl-3 1 4 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 5 unspecified role unspecified role prey prey GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association mlkl-mlkl-1 2 5 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 5 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association mlkl-mlkl-2 3 5 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 5 unspecified role unspecified role prey prey GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association