DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256088X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256082X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256084X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256087X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256086X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256083X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256080X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256085X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS biology 2013 imex curation Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Mukherjee SP., Behar M., Birnbaum HA., Hoffmann A., Wright PE., Ghosh G. DIP original experiment: DIP-256081X PLoS biology 2013 IMEx Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. tf65_mouse Transcription factor p65 Nuclear factor NF-kappa-B p65 subunit Rela Nfkb3 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 protein protein mouse Mus musculus Mouse MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPTRRIAVPTRNSTSVPKPAPQPYTFPASLSTINFDEFSPMLLPSGQISNQALALAPSSAPVLAQTMVPSSAMVPLAQPPAPAPVLTPGPPQSLSAPVPKSTQAGEGTLSEALLHLQFDADEDLGALLGNSTDPGVFTDLASVDNSEFQQLLNQGVSMSHSTAEPMLMEYPEAITRLVTGSQRPPDPAPTPLGTSGLPNGLSGDEDFSSIADMDFSALLSQISS DIP protein Q04207 original sequence version: 158 DIP protein Q04207 original sequence version: 117 DIP protein Q04207-1 original sequence version: 117 DIP protein Q04207-1 original sequence version: 118 DIP protein Q04207 original sequence version: 119 DIP protein Q04207 original sequence version: 141 DIP protein Q04207-1 original sequence version: 141 DIP protein Q04207-1 original sequence version: 149 DIP protein Q04207 original sequence version: 149 DIP protein Q04207 original sequence version: 168 DIP protein Q04207 original sequence version: 125 BDF1673D2FE398B9 cbp_mouse Histone lysine acetyltransferase CREBBP Crebbp Cbp Protein-lysine acetyltransferase CREBBP protein protein mouse Mus musculus Mouse MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQVPGAALPNPLNMLAPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTPTPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQNTALIAPHQIQGRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANINNGMPPGRAGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPVMSMQAQAAVAGPRMPNVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL DIP protein P45481 original sequence version: 148 DIP protein P45481 original sequence version: 126 DIP protein P45481 original sequence version: 152 DIP protein P45481 original sequence version: 115 DIP protein P45481 original sequence version: 127 DIP protein P45481 original sequence version: 123 DIP protein P45481 original sequence version: 149 DIP protein P45481 original sequence version: 156 DIP protein P45481 original sequence version: 169 DIP protein P45481 original sequence version: 175 DIP protein P45481 original sequence version: 135 D89AF52B7BD33347 ep300_mouse Histone acetyltransferase p300 Histone butyryltransferase p300 Histone crotonyltransferase p300 Protein propionyltransferase p300 Ep300 P300 E1A-associated protein p300 Protein 2-hydroxyisobutyryltransferase p300 Protein lactyltransferas p300 protein protein mouse Mus musculus Mouse MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQNSPGLSLINSMVKSPMAQTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGMPSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTGSNMGQQPTGMTTNGPVPDPSMIRGSVPNHMMPRMTPQPGLNQFGQMNMPQPPIGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQASGQNQFLSQTQFTSQGMNVTNMPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPTLPQQAHQNSPSPVPSRTPTPHHTPPSIGNQPPPATAIPTPVPTPPAIPPGPQPPSLHPSSRQTPTPPTHLPPQVQPSLPAAPSADQSQQQPRSQQSTAVSVPTPTAPLLPPQPSTPLSQPAVSIEGQVSNPPSTSSTEVNSQTIPEKQPSQEVKMESKMEVDKPEPADAQPEDTKEAKGEDVKVEPTEMEERGPELKTDGKEEEEQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPSGFVCDGCLKKTARTRKENKLSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQGLPSPTPATPTTPTGQQPATPQTPQPQPTSQPQPTPPNNMTPYLPRTQTTGPVSQGKAPGQVTPPTPPQTAQAPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPQMSPMAPMGMNPPPMARGPGGHLDPGIGPAGMQQQPPWAQGGMPQPQQMQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANPNPQPLPGQPGMTQGQPGLQPPTMPGQQGVHSNPALQNMNPLQAGVQRAGLPQQQPQQQLQPPMGAMSPQAQQMNMNHNTMPSQFRDILRRQMMQQQGAGPGIGPGMANQFQQPQGIGYPPQQQQQQRMQHHMQQMQQGNMGQMGQLPQALGAEAGASLQAYQQRLLQQQMGSPAQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSSDNADLNSNLSQSTLDIH DIP protein B2RWS6 original sequence version: 53 DIP protein B2RWS6 original sequence version: 73 DIP protein B2RWS6 original sequence version: 79 0E9B2D9508237671 crebbp-rela-2 8 10 unspecified role unspecified role prey prey Q04207:p.[Leu449Ala;Phe473Ala] L449A/F473A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A'. Wed May 02 14:53:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,phe473ala' Tue Jun 30 20:24:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Phe473Ala]' Q04207:p.[Leu449Ala;Ser467Ala;Phe473Ala] L449A/F473A/S467A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A/S467A'. Wed May 02 18:06:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,ser467ala,phe473ala' Tue Jun 30 19:11:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Ser467Ala;Phe473Ala]' mouse Mus musculus Mouse 11 unspecified role unspecified role bait bait TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association rela-crebbp-3 7 10 unspecified role unspecified role bait bait Region 441-508 Region 441-508 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Region 425-490 Region 425-490 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Q04207:p.Leu449Ala L449A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A'. Wed May 02 14:41:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala' Tue Jun 30 20:12:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu449Ala' Q04207:p.Leu465Ala L465A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L465A'. Wed May 02 15:42:21 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu465ala' Tue Jun 30 18:11:18 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu465Ala' Q04207:p.Phe473Ala F473A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F473A'. Wed May 02 17:07:56 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe473ala' Tue Jun 30 18:23:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe473Ala' Q04207:p.[Leu449Ala;Phe473Ala] L449A/F473A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A'. Wed May 02 17:27:36 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,phe473ala' Tue Jun 30 18:45:30 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Phe473Ala]' GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 11 unspecified role unspecified role prey prey TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction crebbp-rela-3 4 11 unspecified role unspecified role bait bait mouse Mus musculus Mouse 10 unspecified role unspecified role prey prey Q04207:p.[Leu449Ala;Phe473Ala] L449A/F473A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A'. Wed May 02 19:55:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,phe473ala' Tue Jun 30 18:43:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Phe473Ala]' Q04207:p.Ser276Ala S276A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S276A'. Wed May 02 15:11:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser276ala' Tue Jun 30 16:24:54 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser276Ala' Q04207:p.Ser467Ala S467A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S467A'. Wed May 02 20:00:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser467ala' Tue Jun 30 19:22:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser467Ala' Q04207:p.[Leu449Ala;Ser467Ala;Phe473Ala] L449A/F473A/S467A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A/S467A'. Wed May 02 17:51:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,ser467ala,phe473ala' Tue Jun 30 18:01:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Ser467Ala;Phe473Ala]' mouse Mus musculus Mouse physical association physical association rela-crebbp-4 1 11 unspecified role unspecified role prey prey mouse Mus musculus Mouse 10 unspecified role unspecified role bait bait Q04207:p.[Leu449Ala;Phe473Ala] L449A/F473A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A'. Wed May 02 15:32:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,phe473ala' Tue Jun 30 16:06:56 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Phe473Ala]' Q04207:p.Ser276Ala S276A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S276A'. Wed May 02 14:44:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser276ala' Tue Jun 30 17:35:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser276Ala' Q04207:p.[Leu449Ala;Ser467Ala;Phe473Ala] L449A/F473A/S467A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A/S467A'. Wed May 02 15:30:06 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,ser467ala,phe473ala' Tue Jun 30 18:27:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Ser467Ala;Phe473Ala]' mouse Mus musculus Mouse physical association physical association crebbp-rela-4 2 10 unspecified role unspecified role unspecified role unspecified role Region 425-490 Region 425-490 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 11 unspecified role unspecified role unspecified role unspecified role TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction crebbp-rela-5 3 10 unspecified role unspecified role prey prey mouse Mus musculus Mouse 11 unspecified role unspecified role bait bait TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain KIX domain Region 586-665 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association crebbp-rela-6 6 10 unspecified role unspecified role unspecified role unspecified role Region 441-508 Region 441-508 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Q04207:p.Phe473Ala F473A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F473A'. Wed May 02 17:54:56 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe473ala' Tue Jun 30 16:55:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe473Ala' Q04207:p.Leu449Ala L449A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A'. Wed May 02 16:33:09 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala' Tue Jun 30 17:26:32 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu449Ala' Q04207:p.Leu465Ala L465A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L465A'. Wed May 02 15:00:49 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu465ala' Tue Jun 30 17:27:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu465Ala' ecolx Escherichia coli 11 unspecified role unspecified role unspecified role unspecified role TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction ep300-rela-1 5 10 unspecified role unspecified role prey prey Q04207:p.[Leu449Ala;Phe473Ala] L449A/F473A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L449A/F473A'. Wed May 02 14:55:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu449ala,phe473ala' Tue Jun 30 18:18:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu449Ala;Phe473Ala]' Q04207:p.Ser276Ala S276A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S276A'. Wed May 02 16:46:38 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser276ala' Tue Jun 30 19:53:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser276Ala' Q04207:p.Ser467Ala S467A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S467A'. Wed May 02 15:23:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser467ala' Tue Jun 30 16:41:25 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser467Ala' mouse Mus musculus Mouse 12 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association crebbp-rela-7 9 10 unspecified role unspecified role unspecified role unspecified role Region 425-490 Region 425-490 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 11 unspecified role unspecified role unspecified role unspecified role TAZ1 domain Region 340-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction