DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. PloS one 2012 imex curation Baker RW., Jeffrey PD., Hughson FM. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Baker RW., Jeffrey PD., Hughson FM. DIP original experiment: DIP-262150X PloS one 2012 IMEx Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. PloS one 2012 imex curation Baker RW., Jeffrey PD., Hughson FM. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Baker RW., Jeffrey PD., Hughson FM. DIP original experiment: DIP-262152X PloS one 2012 IMEx Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. PloS one 2012 imex curation Baker RW., Jeffrey PD., Hughson FM. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Baker RW., Jeffrey PD., Hughson FM. DIP original experiment: DIP-262151X PloS one 2012 IMEx Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*. g0scm5_chatd CTHT_0057760 protein protein chatd Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) MAGQFAAKRLGKELQKIRNSLPPGIELVSADNFEEWLLDIRVLDDNPLYANQTYRLRFRFGSTYPIEPPEVVFVKSADRPIPIHPHIYSNGIICLDLLGHQGWSPVQNVESVCMSLQTPRLPTPTWIHNHQTPHGGLVSMAPRAGFDAEQVRDKARKDLLHLLEGVRGKKNLVIEKDLAGPLGVIVKASTLRDYGVDNFFFLENKNTGTSQRNIVFIARGESVRNAHAIAAQIKRIQRESQTSHDFHIFWVPRRTLFSDKVLEEAGVLGDANISELPLYFFPLERDVLSLELNDSFRDLYLAKDPTPVFLLSRALMGIQKKHGLFPRIIGKGENAKRVADLLSRMRQELLAGEEAGESDRAGLSPSTTIESVIIIDREVDFVTPLLTQLTYEGLIDEYFGIQNNQTDVDAVIVGAPAQSAASTSTAVPTNSSQSRKRKIQLDGSDSLYSQLRDANFAIVGSLLNTVARRLKSDYESRHNTKTTAELKEFVKKLPGYQAEQQSLKIHSNIAEEIINYTRTEIFNKLLEVQQNLAAGADPSSQFDSIEELVARDTPLPQVLRLLCLYSCISGGIKTKELDHFRRLVLQGYGHQHLLTLHNLERLQMFLSKSSPLASMITMSGSSGGPDQKTNYTYLRKQLRLIVDEVNEQDPNDIAYVYSGYAPLSIRLVQCVLQKQYLLSITKGSGTVIAAGPVAGGGAQGWKGFEEIVKHARGPTFDEIQKGEDKAVKARALLSGSSGDKKTVFVVFVGGITFTEIAALRFIAKQEEARRNIVICTTSIINGNRMMNAAIETATFEKTTVTTAAAQ DIP protein G0SCM5 original sequence version: 19 DIP protein G0SCM5 original sequence version: 26 g0s6m7_chatd Probable vacuolar protein sorting-associated protein 16 homolog CTHT_0026760 protein protein chatd Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) MDTAHPTASWEQLGERFYRKIQLYTQVFDQDFDLDNYIVTGAPYGGAIALYRDDEKLVAYQPSRSSRPTIDICSLSGKLLRRISWDQGPIKGVGWSEDEKLLIVMVDGTVRCYFDLQSEFTQFSLGHGAEEHGVKSCRFYSHGLVALLGNNALVSVSSYDEPRPKLLASPPEGRVYSWNIIPPAYSLSRSVEVLLSVNQTIYVCDASECEDRFLDIGPFSHIAVSPNGRFCALYTTTGKVHVITSDFQSRLSEHDTKSKIAPNYFEWCGNDAVVIAWDDEVHLVGPSGSLARFFYDSGRIHLIPDFDGVRILANDRCDFLQKVPDVIEEVFGLGADSPASILLDAVEQLEMKSPKADDNIQLIRPHLVEAVDTCVSAAGQEFSIHWQKQLLKAASFGKSVLDIYNSDDFVDMCETLRVLNAVRFYEVGLPLSYEQYQRLSPSGLISRLLNRHEYLLAIRIADHLRLPTDKIHVHWASAKVRLGSEDDDTICRKIVEKLSGKPGISFEVIARTAYEEGRTRLATELLNHEPRAGRQVPLLLSMEEDELALDKAIESGDTDLIYFVIHQLRRKLPLASFFRVVSSRPTASAMVEALARNSDGDGNEDTALLKDLYYQDDRRLDGASVFIREALQQPETRTASDKLDLAANLLQGNQKEHVFELGALKEAKMLLLNQTMFKLIKLGYHGRAKKIQSEFKVPERVAWWIRLQALVAKRDWNEIEEISRQRKSPIGWEPFFNQVLQAGNPRLAATFIPKCTNLEPGQTITMYEKCGMRVKAAEEAVRLKDTEAWNRLLEAAGRNTAEGREIERLGATVFKK DIP protein G0S6M7 original sequence version: 13 DIP protein G0S6M7 original sequence version: 18 g0s6m7_chatd-g0scm5_chatd-1 1 5 unspecified role unspecified role unspecified role unspecified role 505-834 binding region 505-834 binding region sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction g0s6m7_chatd-g0scm5_chatd-2 3 5 unspecified role unspecified role unspecified role unspecified role 505-834 binding region 505-834 binding region sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction g0s6m7_chatd-g0scm5_chatd-3 2 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role G0SCM5:p.[Ala550Asp;His590Asp] A411D/H451D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain H D certain certain sequence position certain certain certain sequence position certain A D Wed May 02 18:10:45 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ala550asp,his590asp' Tue Jun 30 16:15:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ala550Asp;His590Asp]' G0SCM5:p.[Ala550Asp;Leu593Glu] A411D/L454E mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain L E certain certain sequence position certain certain certain sequence position certain A D Wed May 02 19:58:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ala550asp,leu593glu' Tue Jun 30 17:55:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ala550Asp;Leu593Glu]' ecolx Escherichia coli direct interaction direct interaction