DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. PLoS biology 2012 imex curation Holst B., Madsen KL., Jansen AM., Jin C., Rickhag M., Lund VK., Jensen M., Bhatia V., Sørensen G., Madsen AN., Xue Z., Møller SK., Woldbye D., Qvortrup K., Huganir R., Stamou D., Kjærulff O., Gether U. Only protein-protein interactions rat Rattus norvegicus (Rat) Rat anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holst B., Madsen KL., Jansen AM., Jin C., Rickhag M., Lund VK., Jensen M., Bhatia V., Sørensen G., Madsen AN., Xue Z., Møller SK., Woldbye D., Qvortrup K., Huganir R., Stamou D., Kjærulff O., Gether U. DIP original experiment: DIP-252435X PLoS biology 2012 IMEx PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. PLoS biology 2012 imex curation Holst B., Madsen KL., Jansen AM., Jin C., Rickhag M., Lund VK., Jensen M., Bhatia V., Sørensen G., Madsen AN., Xue Z., Møller SK., Woldbye D., Qvortrup K., Huganir R., Stamou D., Kjærulff O., Gether U. Only protein-protein interactions drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Holst B., Madsen KL., Jansen AM., Jin C., Rickhag M., Lund VK., Jensen M., Bhatia V., Sørensen G., Madsen AN., Xue Z., Møller SK., Woldbye D., Qvortrup K., Huganir R., Stamou D., Kjærulff O., Gether U. DIP original experiment: DIP-252436X PLoS biology 2012 IMEx PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. q9vp78_drome ICA69 Dm ric-19 Dmel\CG10566 ICA-69 dCG10566-PA Dmel_CG10566 CG10566 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MLKSEVQHQFWITKKVVQRKLGTKEDKHIISSDAELDSKIEVFKSISDTSLNLCKIIDQYQERLCILSQEECVFGRFLKEAGKRSRTTGGSIAHTAKAVSFAGQQRMCVRVPLLRLQHEVDVFRCRAIKDTEQTLQTMEKERTEYRAALSWMKSASQELDPDTGKGLDKFRTAQAHVRVAKHNFDGYSMDSIQKIDLLAAARCNMYSHALVAYVTELKNFAQKAASTFQTISKALIIKPKYDFCVLKELSQNEGSTEEVPPIEAVDKDQSLFFANEYQDKLETQPEIKESEEDKPSAPPNACGDNESLLIELSKQLEDSPLIDAPLDEDIPAQNSTNKLWSRLFSQQNQQPIPSQVATDSKASAGGATPVPSKSQTTNNPWLDLFADLDPLANPQAFDLKLSGGRSVAEQT DIP protein Q9VP78 original sequence version: 93 AAE20ECC922C110D ica69_rat Islet cell autoantigen 1 Ica1 69 kDa islet cell autoantigen Islet cell autoantigen p69 protein protein rat Rattus norvegicus (Rat) Rat MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQKEEGKSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDEGEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA DIP protein Q63054 original sequence version: 82 q8sy07_drome PRKCA-binding protein PICK1 Dmel\CG6167 dPICK1 CG6167 Dmel_CG6167 Protein interacting with C kinase 1 Protein kinase C-alpha-binding protein protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MLTDTEDDFFFEEDKMGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEKDGLGIIKQIKPVLADLGTYLNKAIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVDFKETDFQYKSSTLKPQELDDDEIEANNHPHSTPSQVDCGFEAVEQPAAIINVEAAKASVDSSTLQSASENETLLKELGLYDVDLLSNPQTISNQKDSIAAQNDGYDFDLFLNQATAATTSLERDLMSSNAEEMDLLLQ DIP protein Q8SY07 original sequence version: 92 099A753707DCEAE4 pick1_rat PRKCA-binding protein Pick1 Prkcabp Protein kinase C-alpha-binding protein Protein interacting with C kinase 1 protein protein rat Rattus norvegicus (Rat) Rat MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLRDADVFPIEVDLAHTTLAYGPNQGGFTDGEDEEEEEEDGAAREVSKDARGATGPTDKGGSWCDS DIP protein Q9EP80 original sequence version: 84 DIP protein Q9EP80 original sequence version: 104 DIP protein Q9EP80 original sequence version: 122 8FDE0D78BB26C006 pick1-ica1-2 1 4 unspecified role unspecified role prey prey rat Rattus norvegicus (Rat) Rat 6 unspecified role unspecified role bait bait rat Rattus norvegicus (Rat) Rat physical association physical association ica69-pick1-1 2 5 unspecified role unspecified role prey prey drome Drosophila melanogaster (Fruit fly) Fruit fly 3 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association