DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Nature 2013 imex curation Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. DIP original experiment: DIP-252047X Nature 2013 IMEx Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Nature 2013 imex curation Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. DIP original experiment: DIP-252045X Nature 2013 IMEx Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. Nature 2013 imex curation Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Arai S., Saijo S., Suzuki K., Mizutani K., Kakinuma Y., Ishizuka-Katsura Y., Ohsawa N., Terada T., Shirouzu M., Yokoyama S., Iwata S., Yamato I., Murata T. DIP original experiment: DIP-252046X Nature 2013 IMEx Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures. ntpd_entha V-type sodium ATPase subunit D ntpD Na(+)-translocating ATPase subunit D V-type sodium pump subunit D EHR_08270 protein protein entha Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) MRLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILLIRKNNELRQAIEKETQTAMKDFVLAKSTVEEAFIDELLALPAENVSISVVEKNIMSVKVPLMNFQYDETLNETPLEYGYLHSNAELDRSIDGFTQLLPKLLKLAEVEKTCQLMAEEIEKTRRRVNALEYMTIPQLEETIYYIKMKLEENERAEVTRLIKVKNMGTEE DIP protein P43435 original sequence version: 65 ntpa_entha V-type sodium ATPase catalytic subunit A ntpA Na(+)-translocating ATPase subunit A V-type sodium pump catalytic subunit A EHR_08260 protein protein entha Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) MQIGKIIKVSGPLVMAENMSEASIQDMCLVGDLGVIGEIIEMRQDVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEVTQSNFLGRGVQLPALDHEKQWWFEATIEEGTEVSAGDIIGYVDETKIIQHKIMVPNGIKGTVQKIESGSFTIDDPICVIETEQGLKELTMMQKWPVRRGRPIKQKLNPDVPMITGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKWSDVDLVVYVGCGERGNEMTDVVNEFPELIDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSDQREGSITAISAVSPSGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSINWIQSYSLYSTEVGRYMDQILQQDWSDMVTEGMRILQEEEQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDDVDTFTSREKQFNMLKVILTFGKEARKALSLGAYFNEIMEGTVAVRERISRSKYIPEEELAKISSINEEIKETIQLIVSEGGMTDD DIP protein Q08636 original sequence version: 72 ntpb_entha V-type sodium ATPase subunit B ntpB Na(+)-translocating ATPase subunit B V-type sodium pump subunit B EHR_08265 protein protein entha Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) MIKEYRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDKAMVQIFEGTSGINLKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNGPEILPEKYLDINGEVINPIARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPAIERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGIQPPIDVLPSLSRLKDKGTGAGKTREDHAATMNQLFAAYAQGKQAKELAVVLGESALSDIDKIYAKFAERFENEYVNQGFYTNRTITETLDLGWELLAMLPRTELKRIKDDLLDKYLPEGK DIP protein Q08637 original sequence version: 70 ntpg_entha V-type sodium ATPase subunit G ntpG ntpQ EHR_08255 Na(+)-translocating ATPase subunit G V-type sodium pump subunit G protein protein entha Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) MTYKIGVVGDKDSVSPFRLFGFDVQHGTTKTEIRKTIDEMAKNEYGVIYITEQCANLVPETIERYKGQLTPAIILIPSHQGTLGIGLEEIQNSVEKAVGQNIL DIP protein P43455 original sequence version: 63 ntpa-ntpb-1 1 7 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 4 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 6 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 5 unspecified role unspecified role unspecified role unspecified role in vitro In vitro physical association physical association ntpa-ntpb-2 2 6 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 5 unspecified role unspecified role unspecified role unspecified role in vitro In vitro direct interaction direct interaction ntpa-ntpb-3 3 7 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 4 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 6 unspecified role unspecified role unspecified role unspecified role in vitro In vitro 5 unspecified role unspecified role unspecified role unspecified role in vitro In vitro physical association physical association