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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="23260654" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="https://doi.org/10.1016/j.str.2012.11.010" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16028618" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-20744" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</attribute>
            <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2013</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Volbeda A.,  Darnault C.,  Parkin A.,  Sargent F.,  Armstrong FA.,  Fontecilla-Camps JC.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-20744" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-251881X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="23260654" refType="primary-reference" refTypeAc="MI:0358"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="562">
            <names>
              <shortLabel>ecolx</shortLabel>
              <fullName>Escherichia coli</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>molecular sieving</shortLabel>
            <fullName>molecular sieving</fullName>
            <alias type="go synonym" typeAc="MI:0303">Gel Filtration</alias>
            <alias type="go synonym" typeAc="MI:0303">Size Exclusion Chromatography</alias>
            <alias type="synonym" typeAc="MI:1041">Size Exclusion Chromatography</alias>
            <alias type="synonym" typeAc="MI:1041">Gel Filtration</alias>
            <alias type="synonym" typeAc="MI:1041">Sizing column</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0071" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1175" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Volbeda A., Darnault C., Parkin A., Sargent F., Armstrong FA., Fontecilla-Camps JC.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251881X</attribute>
          <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2013</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="23260654" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="https://doi.org/10.1016/j.str.2012.11.010" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16028618" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-20744" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</attribute>
            <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2013</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Volbeda A.,  Darnault C.,  Parkin A.,  Sargent F.,  Armstrong FA.,  Fontecilla-Camps JC.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-20744" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-251882X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4GD3" refType="identity" refTypeAc="MI:0356"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="562">
            <names>
              <shortLabel>ecolx</shortLabel>
              <fullName>Escherichia coli</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Volbeda A., Darnault C., Parkin A., Sargent F., Armstrong FA., Fontecilla-Camps JC.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251882X</attribute>
          <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2013</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>mbhs_ecoli</shortLabel>
          <fullName>Hydrogenase-1 small chain</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Membrane-bound hydrogenase 1 small subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NiFe hydrogenase</alias>
          <alias type="locus name" typeAc="MI:0305">JW0954</alias>
          <alias type="locus name" typeAc="MI:0305">b0972</alias>
          <alias type="gene name" typeAc="MI:0301">hyaA</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P69739" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P19928" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblbacteria" id="AAC74057" version="SP_129" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="BAA35737" version="SP_129" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9124108" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_415491.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_001058323.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-47848N"/>
          <secondaryRef db="ensemblbacteria" id="AAC74057" version="SP_129" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="b0972" version="SP_129" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAA35737" version="SP_129" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAA35737" version="SP_129" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006113" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008901" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009055" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009061" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009375" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4I" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4M" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ADU" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JRD" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FPI" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FPW" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G7R" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GAL" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RP2" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031237" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033748" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044569" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051538" version="SP_129"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051539" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001821" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006137" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006311" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019546" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027394" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037024" version="SP_129"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037148" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UQY" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3USC" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3USE" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GD3" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UE3" version="SP_129"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4F" version="SP_129"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="83333">
          <names>
            <shortLabel>ecoli</shortLabel>
            <fullName>Escherichia coli (strain K12)</fullName>
          </names>
        </organism>
        <sequence>MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAWALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAEEVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTCASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGVVAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P69739 original sequence version: 71</attribute>
          <attribute name="remark-internal">DIP protein P69739 original sequence version: 93</attribute>
          <attribute name="crc64">4AD3ECB4220D2826</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>cybh_ecoli</shortLabel>
          <fullName>Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit</fullName>
          <alias type="gene name" typeAc="MI:0301">hyaC</alias>
          <alias type="locus name" typeAc="MI:0305">b0974</alias>
          <alias type="locus name" typeAc="MI:0305">JW0956</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P0AAM1" version="SP_20" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P19929" version="SP_20" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblbacteria" id="AAC74059" version="SP_115" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="BAA35739" version="SP_115" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1134138" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_001186424.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_415493.1"/>
          <secondaryRef db="ensemblbacteria" id="BAA35739" version="SP_115" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005506" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006113" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009055" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009061" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0020037" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0022904" version="SP_115"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044569" version="SP_115"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000516" version="SP_115"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011577" version="SP_115"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016174" version="SP_115"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GD3" version="SP_115"/>
          <secondaryRef db="ensemblbacteria" id="AAC74059" version="SP_115" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="b0974" version="SP_115" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAA35739" version="SP_115" refType="gene"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35859N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="83333">
          <names>
            <shortLabel>ecoli</shortLabel>
            <fullName>Escherichia coli (strain K12)</fullName>
          </names>
        </organism>
        <sequence>MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLPSVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWWQGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIFAPFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMVNGYRSHKFGKISNKERS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P0AAM1 original sequence version: 62</attribute>
          <attribute name="crc64">98048DC800AB02C7</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>mbhl_ecoli</shortLabel>
          <fullName>Hydrogenase-1 large chain</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Membrane-bound hydrogenase 1 large subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NiFe hydrogenase</alias>
          <alias type="gene name" typeAc="MI:0301">hyaB</alias>
          <alias type="locus name" typeAc="MI:0305">b0973</alias>
          <alias type="locus name" typeAc="MI:0305">JW0955</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P0ACD8" version="SP_20" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P19927" version="SP_20" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P78056" version="SP_20" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblbacteria" id="AAC74058" version="SP_118" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="BAA35738" version="SP_118" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-851493" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_415492.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000107384.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-36180N"/>
          <secondaryRef db="ensemblbacteria" id="AAC74058" version="SP_118" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="b0973" version="SP_118" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAA35738" version="SP_118" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAA35738" version="SP_118" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006113" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008901" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009055" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009061" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016151" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030288" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033748" version="SP_118"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044569" version="SP_118"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001501" version="SP_118"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018194" version="SP_118"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029014" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UQY" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3USC" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3USE" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GD3" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UE3" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4F" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4I" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A4M" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ADU" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JRD" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LMM" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LRY" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FPI" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FPO" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FPW" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G7R" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G94" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GAL" version="SP_118"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RP2" version="SP_118"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="83333">
          <names>
            <shortLabel>ecoli</shortLabel>
            <fullName>Escherichia coli (strain K12)</fullName>
          </names>
        </organism>
        <sequence>MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVITNAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDNANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSPGYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVKIHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMIPDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNVLPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLGRILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAPRGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEILRTLHSFDPCLACSTHVLGDDGSELISVQVR</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P0ACD8 original sequence version: 60</attribute>
          <attribute name="remark-internal">DIP protein P0ACD8 original sequence version: 81</attribute>
          <attribute name="crc64">659DD7EDE16D6342</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-20744-1">
        <names>
          <shortLabel>hyaa-hyab-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-190400E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16028637" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-20744-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="8">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="9">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="10" imexId="IM-20744-2">
        <names>
          <shortLabel>hyaa-hyab-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-190400E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16028656" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-20744-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="12">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="13">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>