DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America 2012 imex curation Spurny R., Ramerstorfer J., Price K., Brams M., Ernst M., Nury H., Verheij M., Legrand P., Bertrand D., Bertrand S., Dougherty DA., de Esch IJ., Corringer PJ., Sieghart W., Lummis SC., Ulens C. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Spurny R., Ramerstorfer J., Price K., Brams M., Ernst M., Nury H., Verheij M., Legrand P., Bertrand D., Bertrand S., Dougherty DA., de Esch IJ., Corringer PJ., Sieghart W., Lummis SC., Ulens C. DIP original experiment: DIP-251812X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America 2012 imex curation Spurny R., Ramerstorfer J., Price K., Brams M., Ernst M., Nury H., Verheij M., Legrand P., Bertrand D., Bertrand S., Dougherty DA., de Esch IJ., Corringer PJ., Sieghart W., Lummis SC., Ulens C. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Spurny R., Ramerstorfer J., Price K., Brams M., Ernst M., Nury H., Verheij M., Legrand P., Bertrand D., Bertrand S., Dougherty DA., de Esch IJ., Corringer PJ., Sieghart W., Lummis SC., Ulens C. DIP original experiment: DIP-251811X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. elic_dicch Cys-loop ligand-gated ion channel ELIC protein protein erwch Erwinia chrysanthemi Pectobacterium chrysanthemi Erwinia chrysanthemi APADNAADARPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQAMGVEDDLLIQRCRLAFPLGFLAIGCVLVIRGITL DIP protein P0C7B7 original sequence version: 22 DIP protein P0C7B7 original sequence version: 15 DIP protein P0C7B7 original sequence version: 23 DIP protein P0C7B7 original sequence version: 31 DIP protein P0C7B7 original sequence version: 34 DIP protein P0C7B7 original sequence version: 25 elic_dicch-12 2 3 unspecified role unspecified role unspecified role unspecified role Region 11-316 Region 11-316 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction elic_dicch-13 1 3 unspecified role unspecified role unspecified role unspecified role Region 11-316 Region 11-316 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction