DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250589X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250591X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250592X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting western blot western blot Immuno blot Immuno blot Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250588X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250593X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip ms participant Identification by mass spectrometry ms participant Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250594X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS biology 2011 imex curation Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250590X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. pncb_caeel Nicotinate phosphoribosyltransferase nprt-1 Y54G2A.17 protein protein caeel Caenorhabditis elegans MSFILPSESIDGTHPCNGLHMNGQDSLVQPLLTDFYQITMCYAYWKTGTHNEPAVFDVFFRKNPFQGEFTVFAGLEDCLRFVENFKFSQSDIDYVKKILPENAEPEFYEYLETLNGSHLTIEAVAEGSVVFPKVPLLTINGPLAMCQLIETSILNLVNYASLVATNAARFRQASGWKIQLLEFGLRRAQGPNGGLTASKYCYIGGFDATSNVLAGKLYGIPVKGTQAHSFICSFSSPAELKVRLLNHKITNEKADLFQISMEKRAWLLDQFSWKAALSEVSDGELSAFVAYAIAFPDTFLALIDTYDVIRSGVVNFVAVSLALHDLGYRSMGCRIDSGDLSYLSKELRECFVKVSTLKGEYKFFEKMSIVASNDINEETIMSLNDQQHEINAFGVGTHLVTCQKQPALGCVYKLVAQSAQPKIKLSQDVTKITIPGKKKCYRIFGKNGYAILDLMMLEDEPEPQPNQQILCRHPFEESKRALVNANKIIKLHNVYWKDGEMITPLPTLNEIKEHVNESIRSTLRQDHRRYLNPTPYKVSVSERLYQFLHTLWLQNAPIGQLE DIP protein Q95XX1 original sequence version: 71 glc7a_caeel Serine/threonine-protein phosphatase PP1-alpha CeGLC-7-alpha Glc seven-like phosphatase 1 F29F11.6 gsp-1 protein protein caeel Caenorhabditis elegans MSNDGDLNIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYQGMNSGRPAVGGGRPGTTAGKK DIP protein Q27497 original sequence version: 86 500145324CA16D1B lab1_caeel Long arms of the bivalent protein 1 lab-1 C03D6.6 protein protein caeel Caenorhabditis elegans MVSHKKNDRPRPLWILKIHKRLSLFEFKRYATGIGKDDGQDISWVLKGNAKNNVYQVTVETMENCETDECKKVIWVPDELAESTGTMFEDFKEDQPQESVSSISNNEANWGSSVNELDENYEKMQKEETFDPYDSDSDTSEDSDFDEDFEDSDKTMCSGQS DIP protein Q17604 original sequence version: 62 o01820_caeel htp-3 F57C9.5 CELE_F57C9.5 protein protein caeel Caenorhabditis elegans MDESFDSSVVPGSLTSDDRAIFNEQTLKNGDENSKSSLEVMANCVYLANSTILRERKVIPAEYFQDFQVYGDVSGYTLRQDIPEGRSVSSKLLASHDAIRQKLLQKLAIVVEESLNTNPVETFVWTFVYDSTTSASAEIGYGGRKSKFVVNYLNMDDTAQQFCKMFSELRNVLSLLRPLPRGLIPSMKVAYRGEPEFVPGFQQVDDFVNPEQINLGAVSFPHGNGFQFAYASKFMVEQPSAIRPPVEVSHFEDDLLNSTITPIEVVRDNTMNCAENPELDEIYFSPGRQEVRMDEDVANESIRCNPSMASEMMVLQSEYNVLIADNDEVPMVVERERSPIVKAAKKRSTRAPAVPITPTEPASPVESPVKEQPQKAPKAQMRRSSKRTTKNNERCEQKEEEPIVNPKRRSARRLVPPVEVDEQPEEQNDDDAQNSLQIDSDAQNSLQIDSDAIITSPEKRNESKSAIPEEAADLDNTTSEKQESSTARYGVSNTSINRKKPDPVANPVSEEAQVDLANGSIPDKRPRKRKYGRVSSILDVADLPTDDTVEEDVRESPIYGRVPSILDVARAEENDAQNDAQDAQNEIAVEGLADLSIDTEQHEEAAPINVTGHQSESVPIIVTEHQSEEAQTVVTEQPAGAASVIAAERHYGRVSSILDVAGSFADVDPSGAAPAIATERHYGRVSSILDVAGSLSDVDPQEDTESSTQNQSTSKKFKPNPPKAMRYGQSPNMPSRRGN DIP protein O01820 original sequence version: 67 6D2A04D339FE88F8 uba5_caeel Ubiquitin-like modifier-activating enzyme 5 uba-5 T03F1.1 protein protein caeel Caenorhabditis elegans MSDEQIDKLVSRLDGALNRLGNVKKDHPLESSSNSKPTHQPKSPAPYRQKIEKLSAEVVDSNPYSRLMALQRMGIVNEYERIREKTVAVVGVGGVGSVVAEMLTRCGIGKLILFDYDKVEIANMNRLFYQPNQAGLSKVEAARDTLIHVNPDVQIEVHNFNITTMDNFDTFVNRIRKGSLTDGKIDLVLSCVDNFEARMAVNMACNEENQIWMESGVSENAVSGHIQYIEPGKTACFACVPPLVVASGIDERTLKRDGVCAASLPTTMAVVAGFLVMNTLKYLLNFGEVSQYVGYNALSDFFPRDSIKPNPYCDDSHCLQRQKEYEEKVANQPVDLEVEVPEEETVVHEDNEWGIELVNESEPSAEQSSSLNAGTGLKFAYEPIKRDAQTELSPAQAATHDFMKSIKDKLVEEAQNKGK DIP protein P91430 original sequence version: 87 BA61B08DB8AC8F4C pid4_caeel Protein pid-4 piRNA-induced silencing defective protein 4 W03G9.2 pid-4 protein protein caeel Caenorhabditis elegans MNTHNARDSDDESPLESEEHLKRFFAGRNLYSQTKIDDARKKSHDAKYAKEVEWDAKDTAKGKPVFKKYRQEIADKTSRCDAQFINNLHTYYGNGSELRELPETHYAVDFMGTTIATTEMTAELKKLKVLKKKTATSQFVREHRQLGFIPTPSRRSLSCTGRFMNFETKCDERPDRTNPEFSVGNNNFLSATISNLDEDFKTPSNCEHVASIVPKEISNALTALIPHVNVFDYEKGEMEIGKVLCSNKNLHAYVIPKQHDQEQMLKDFSARFLAWYNKLSHLQRDTFGTDKDPKRSGKQEDGKPMKPYFWRVNVILCLQEFQEEGTMFRRARHVCGIRPHKSQPGLDLYIEIDTGSMRALKTNYLTVRKLPQEFANVPTPILEVRFEGAKTEEDVARRIAHIRKTGRAYIKSFDTGKRKIYQNSFFNGQPKDWSNIETAVLLPPKESSMSKLFCEDRDCMGLCCTDQWLENAESSPGISTIPASWIADKNKKPFVDRSPQKFKFPASGSYMKPAN DIP protein O44749 original sequence version: 72 DFB6C19D4F17191B crtc1_caeel CREB-regulated transcription coactivator 1 homolog crtc-1 Y20F4.2 protein protein caeel Caenorhabditis elegans MSNSNTPRKFSEKIAILERKQNEENTTFEDIMRQVQSITHHPTDSSGSSTATAPMPIPQQGLLPPQQPWGHNLGGSLPNVHQMPSYSPPQWPPNWQHEIQHRPIQGHRSRSPEDHMIGSASGSPSHHYHPYGMRSNGLSRSPDRTPPQHPQYTPYGPPYNQPGQLVPPESWNQINRARSDPAIHNMGGMVPMHPHHHQQQQMAFHQMPHYLQNSMPGPSGMMAPNSQSQQHSPQLTPQGSQQGSPVQMHHQIPPPLQMGNNQQMGGGNNGMSPLQSPNHMMTPMYGYHNGSPLHSPMDSPHASTLMLDGSGTPSPYMEVSPPGMHDFNQDAGSLPNLQNVQQQQQQQQEIYTNGGAPGGGYYHAPIGPRHSTGACGPRLVPGPALTPESQSAPTSPHNQLDPNQPPMWPTRTFSNSPEALDIPKLTITNAEGAPGHHVDSYNDFNDLGLDSLDSVLCNGAPPQTISNHQTPNNSFHDPGGTQMLQN DIP protein Q95XA8 original sequence version: 53 F8B572680FEB9FE8 glc7b_caeel Serine/threonine-protein phosphatase PP1-beta Glc seven-like phosphatase 2 gsp-2 CeGLC-7-beta F56C9.1 Ce-glc-7beta CeGLC-7beta glc-7 protein protein caeel Caenorhabditis elegans MDVEKLNLDNIISRLLEVRGSKPGKNVQLTESEIKGLCQKSREIFLSQPILLELEAPLKICGDVHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGSMMTVDETLMCSFQILKPADKKKYPYGAGGVGSNRPVTPPRNAPAAQPKKGAKK DIP protein P48727 original sequence version: 92 A73CE460AC78054E a9ujn7_caeel maph-1.2 CELE_F25D7.4 F25D7.4 protein protein caeel Caenorhabditis elegans MPEEYIMSSKACIYVLGGAANTAALFDFDGVYILDGGFAEKNPGFVAHVRDVSAVLLAAPTLGNLGTTSALLEQGKPLPVFTNTKPFKTAKPGSSGEIAKAIQEANSKLLSVAPPLFNPKYPAHIIYQSAAKGVLSMYILAGDVKDSDMITKALAGGNEAEVEKAAAENGTIGVLLWRPAMTDQSAVRVLISGTSSLARIQQSLDKAAKSLPFLNAPTVKSKDALLGIPAPAVPRPVAGKPSTRSASTTGAARTRPAVPAVSAPRALTSRAPAGPARPTTTRSATPATRTAVPPRATAPPKAAPASKAPTRAPIPARSAPAPPRGAPAKAPKAEPIAQKKVAGKVQRAAPSKPASAVSAPKATAPASTSSAPATAPEASRRDPNDVTIVLDDSLFPEDFNQGSAPMDIVVIPPTPEPPRLEEARATHPKEPIVDAEDLAKAPHEVDDVANLADVEDEIPPPVDAFKKPEPRPETNVAGGSGEDRISEPVDAFKKPDPVELDDFDPLKPSHPDPSAPVVPSGDLIIATPDPELPNIVAAVPFIPPSPKGPNDGLVKLDDELEKIAPGFEEPLIPQAPRDDGTLAEFNEDVSKLVDISMDTNSAEVAADLAKAVGEVTQLSAELQNLALDEKTDEYVRKLSNQMIEDATLPFTSALASSIVTSNGSETNGHGEQAHAAQNGGIKIPKHDLMQSHSNVIENGAAVKYEKTDPALDAVLNACAQESEQIDASHPENLHMPAAPGSVASAKPVKFARPYYFDVVTVPRNEKLETSVEADGLQEFISKVRSRNVILASKEISGEQLQSILRGKQTWCDRAHPCNVIPTHSSPMLHDFRQKNEEQFAANHLQFSMPVEKQRTTVSSDAGVVEYDLARVDLL DIP protein A9UJN7 original sequence version: 28 gls2_caeel Putative glutaminase 2 glna-2 L-glutamine amidohydrolase DH11.1 protein protein caeel Caenorhabditis elegans MTSKPTTQKSVMYRIPSERTLESLHEMIGSRMSKMSLKNTLRGISNPYERDENEGSEDMIFELFKIPNKNEASIGKLLTVLRQLGLRDDDPRLVPMMEKIKDFEKIAEEKCSEATEQKHWKLTKEQFKECIAPSIDIVSRALQTDMVIPNWVTFVDQIRTLFNECKEIREGQVATYIPQLARQSPNLWAVSLCTVDGQRASFGDVKHPFCVQSVSKAFNYAIVASDLGADVVHSYVGQEPSGRLFNEICLDSTNKPHNPMVNSGAIVITSLIKSKTNMADRFDFVLNQYRKIAGNEFIGFNNATFLSERATADRNYALSYFMKENRCFPKETESLTDALDFYFQLCSVEVTCESLAVMASTLANGGVCPITNETCVDPNPCRDVLSLMYSCGMYDASGQFSFNVGLPAKSGVSGAMIVVVPNVMGICLFSPPLDSLGNSCRGVAFCKKLVSTFNFHNYDCLVHNSNIKSDPRRRDIRERDRLIPVFHVARAGDLPTMRRLYMQGEDLNTSDHDDRTVLHIAATEGYETMIKFLVNVAKVDVDKKDRWGRTPLDEAKFFKHDHVSRFLEKAMKRPEQHRKDSVSSLDTDDEIDDDGFPEKPSFTID DIP protein Q19013 original sequence version: 88 g5efv4_caeel Y48B6A.14 hmg-1.1 CELE_Y48B6A.14 protein protein caeel Caenorhabditis elegans MAKAAAGKKASPVKRVKKGGKAKDPNAPKRAMSAFFFWMQENRERIKKPGMGVADVAKAAGVEWGKLTDKSRWEKKAADDKKRYEVDIANYKKSQ DIP protein G5EFV4 original sequence version: 7 D02C169D65790FF1 q8wqe8_caeel F56C9.11 lab-2 CELE_F56C9.11 protein protein caeel Caenorhabditis elegans MPPHPSTTWKDYMLDNLKIEGETLKRASEEQVINTVVDVLRDIGFNLPNLKIVVQKFGYMPDDDSEVDQRYYVCFEVDSNSSAEMFEQRHGKTKKIHRMNKKSSEMDHKKWLKLKQYIGFNAEIIQKTLREAKRIMSEHPYPSSDGFRLTCNRNMIVLYFDDKKESTINIEQLARNYRKVFDKAIESLSEQARNTINRLILMEPNTQKRGISDETVSNASPPEKSPRLVNSPMPAMNQLLSPILPN DIP protein Q8WQE8 original sequence version: 56 2C13640ADDE179C4 g5ebg0_caeel him-3 CELE_ZK381.1 ZK381.1 protein protein caeel Caenorhabditis elegans MATKEQIVEHRESEIPIASQWKATFPVDLEIEKNSEMFALRYIKCASAFILDRRGILDEKCFKTRTIDKLLVTAFQSSVPAAKRVSSTFDGLRDAIQQGYLREFAIVFYKKPNEEDINEVFAFRFAYGDEGEIFVSLNNGIDTNESSQELLQAKFVDTDNTKQMFASTIKKLHRCIKKMEPLPQGSDASFRVSYTEKAPKDYTPEGYLLSPMFYTLNQDIRKASIGIVCGGHHKIQMLAASQYLKQDFDLDKTTTLNPNMSIMANQSKRKGRISRDSPYGLSQGITKKNKD DIP protein G5EBG0 original sequence version: 7 01D2DD21E590168F q20981_caeel Major sperm protein F58E6.5 CELE_F58E6.5 protein protein caeel Caenorhabditis elegans MTTAPDLTKVVFNPSKSVTFAPVEKKQAVSIEVINNSTSDVAVKFKNTGPNVYKTQPPQAKIGVGEKKVFKCIFKGLPKEKCKTNDRFTVVYIAASKNVVIEKAWKNAHKTCTMKHKIAILFQGVNDQKENETQQPTNNDDDEDKDRQGQLRSKSKVETAKGKKATVVMFVRKEGDSVSDEEDDEGAVEGAEHTNPAGVATSNEAGNMSELRTTRPAGAFTGVVASNDNPMSELRTTRPAGNFSGQTASTPGGAVDPKSMGLKTTRPAGAFTGQVASNGSTDGQELRTTKPAGTYDNPQKKNQK DIP protein Q20981 original sequence version: 83 23C654EC57659153 sydc_caeel Aspartate--tRNA ligase, cytoplasmic dars-1 Aspartyl-tRNA synthetase drs-1 B0464.1 protein protein caeel Caenorhabditis elegans MADAAEGEQPKLSKKELNKLARKAKKDEKAGEKGGNQQQAAAMDQEDASKDFYGSYGLVNSKEKKVLNFLKVKEINVSNATKDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVYATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQLAVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGGANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIRLASLFPRDPKRLTP DIP protein Q03577 original sequence version: 95 q95xc8_caeel htp-2 CELE_Y73B6BL.2 Y73B6BL.2 protein protein caeel Caenorhabditis elegans MAPLENNYNESLNKSKDAIDDKTWSKLFPSIVSDPDRSSNFMIRAIYVVFSAVLRQRNILEKEYFSKNYITENLSCMTLSFKNLRAHQIAQLLRAAGDATKDGFLKEISLVVTEHDGDVEAIEVFSMKFIYFENGGVVARLSTDNNDQEDPHFAELAQLRYEGAESVRDQMVTIVRSVQFLCTKVLEPLPAEFTANFRLKYTNDAPSNFRIDGFDDSSTFYTLPDGIQSVTIGHLRPGHHAAHMQCWSKSMSDSYAAELTLKGHLDKVSDMYAFNPVNVLYKSFNSEDTDPGLSQDTTESANDQGGNVTSPVDNITDSLEKTQMSPIKMRPTTRRGADDSKTRSSPYSRSRK DIP protein Q95XC8 original sequence version: 54 pth2_caeel Probable peptidyl-tRNA hydrolase 2 C24G6.8 protein protein caeel Caenorhabditis elegans MSENIPDIDPNELLPNAPGQHQDLGVDNPPEPDNASIRAERGSPTPSSVTVDNAPSLPDRSFSHLPINDPFSGEIPEVPIPSSAISISSQALSDPVPTPSDTSRPGILRNDEQGSTSSHPVDPQEPNEVNNEYLAHLLDLGFDEYTAVLALKRTNSAGVEQAVAWIVERSNESDFDEDSSSSENEADEEMGAVQSVAGRTHKMVLVANMSLKMGTGKIAAQVGHATLGVYRQAMNSENGQNAIAAWTRHGQVKIVVKGQSTEQLMDLCKVAKDAGCYYYLVQDAGYTQIPAGSRTVLGIFGTVEQVDSVTGGLKLL DIP protein O76387 original sequence version: 77 20E4FA3D52B4EFB0 q18494_caeel maph-1.3 C36A4.5 CELE_C36A4.5 protein protein caeel Caenorhabditis elegans MPEEYIMSSKACVYVLGGAANTATLFDFDGVYILDGGFAEKSPGFVAHVRDVSAVLLAAPTLGNLGTTSALLEQGKPLPVFTNTKPFKTAKPGSSGEIAKAIQEANSKLLSVAPPLFSPKYPAHIIYQSAAKGVLSMYILAGDVKDSEVITKALAGGNEAEVEKAAAENGTIAVLLWRPAMTDQSAVRVLISGTSSLARIQQSLDKAAKSLPFLNAPTVKSKDALLDIPAPAVPRPVAGKPSTRSASTTGAARTRPAIPAVSAPRALTSRAPTGPACPTTTRSAAPATRTAVPPRATAPPKAASASKAPIRAPIPAKSAPAPPRGAPAKAAKAEAIAQKKVAGKVQRAAPSKPASAVSAPKATAPASTSSAPATAPEASRRDPSDVTIVLDDSLFPEDFNQGSAPMDIVVIPPTPEPPRLEEARATHPKEPIVDAEDLAKAPQEVDDVANLADVEDEIPPPVGAFKKPEPRPETIVAGGSGEDRIPEPVDAFKKPDPVELDDFDPLKPSHPDPSAPVVPSGHLIVATPDPELPNIVAAVPFIPPSPKGPNDGLVKLDDELEKIAPGFEEPLIPQAPRDDGTLAEFNEDVSKLVDISMDTNSSEVAADLTKAVGEVTQLSAELQNLALDEKTDEYVRKLSNQMIEDATLPFTSALASSIVTSNGSETNGHGEQAHAAQNGGIKIPKHDLMQSHSNVIENRAAVKYEKTDPALDAVLNACAQESEQIDASHPENLHMPAAPGSVASAKPVKFARPYYFDVVTVPRYEKLETSVEADGLQEFISKVRSRNVILSSKEISGEQLQAILRGKQTWCDRAHPCNVIPTHSSPMLHDFRQKNEEQFAANHLQFSMPVEKQRTTVSSDAGVVEYDLARVDLL DIP protein Q18494 original sequence version: 63 q20305_caeel htp-1 CELE_F41H10.10 F41H10.10 protein protein caeel Caenorhabditis elegans MAPLETIYDESLNKSADSIDDKKWSKLFPRIVSDPDRSSNFMTRAIYVAFSAVLRNRNILGQEYFTKNYITEKLKCMTLCFRNPRSNQIAQLLRNAGDATKDGFLKEVSLVITNNEGDLEAIEVFSMKFIYFENGGVVARLSTDKNGQEDPHFAKLAQLVYEGGDSVRDQMVTIVRSVQFLCTKVLEPLPEEFTANFRLEYTNDAPSNFRIDGFEDSSTFYTLPDDIQSATIGHLRPGCHAANMECWSMLMSDSYEAELTLKRHLDKVSDRHGFNPVNVLYKSFNSEDSDTSLSQATTESVNDQGGNETSPVDDITESLEKAQMSPIQTRPTTRRGADGSKTRSSPYSRSCK DIP protein Q20305 original sequence version: 69 4C115AB9976FC4E9 o18034_caeel CELE_T05F1.5 T05F1.5 protein protein caeel Caenorhabditis elegans MDRSSDGSKFIEGRVKIGRKRYRFSAEKFLCFSDDSDDEPPIQISGKPASTAKPTSGSPQHHPQPIEQATTNPSVTSSLINQHNRVGNNQGHRSPSPTSSPQLSSPPPSTMVDSLSTHSESSRSNIFETTRNTSHRQQGLDLVEDDVAGTLQVDRALEKSVKMKRVWTGSTPWSPFQLDCSCLTVTCDGFSSKFKRQRVGASSGRFSWFKINTSKPTDAEMVYSKARRNGLSIRELEHDAIPSKLSEFAFHFYTFAVSDEDVSKVNRLIDEDFVGAFNADTLLKNPAQSFFFHNIDQKDVIALCALATHYNLHSVVPPLPPMQLLENDQNILEVIDNQTTMQHLENYLSKKAMEHLARLKTELEHL DIP protein O18034 original sequence version: 54 gsp_1-lab_1-1 4 10 unspecified role unspecified role prey prey ecolx Escherichia coli 9 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction lab_1-gsp_2-1 5 15 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 10 unspecified role unspecified role bait bait Q17604:p.[Val73Ala;Trp75Ala] V73A/W75A mutation increasing strength mutation increasing interaction strength mutation increasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain W A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V73A/W75A'. Wed May 02 16:27:06 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val73ala,trp75ala' Tue Jun 30 19:35:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val73Ala;Trp75Ala]' p.Lys72_Trp75del Δ72-75 mutation increasing strength mutation increasing interaction strength mutation increasing strength deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain KVIW . yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association lab_1-gsp_1-1 2 10 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 9 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association lab_1-gsp_1-2 1 10 unspecified role unspecified role bait bait Q17604:p.[Val73Ala;Trp75Ala] V73A/W75A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain W A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V73A/W75A'. Wed May 02 19:35:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val73ala,trp75ala' Tue Jun 30 16:52:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val73Ala;Trp75Ala]' ecolx Escherichia coli 9 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction lab_1-crtc_1-1 6 16 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 25 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 14 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 27 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 13 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 17 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 21 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 24 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 11 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 22 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 8 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 18 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 12 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 23 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 26 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 19 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 20 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 10 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range caeel Caenorhabditis elegans association association lab_1-lab_1-1 3 10 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 10 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association gsp_2-lab_1-1 7 15 unspecified role unspecified role bait bait ecolx Escherichia coli 10 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction