DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature 2012 imex curation Wu CH., Fallini C., Ticozzi N., Keagle PJ., Sapp PC., Piotrowska K., Lowe P., Koppers M., McKenna-Yasek D., Baron DM., Kost JE., Gonzalez-Perez P., Fox AD., Adams J., Taroni F., Tiloca C., Leclerc AL., Chafe SC., Mangroo D., Moore MJ., Zitzewitz JA., Xu ZS., van den Berg LH., Glass JD., Siciliano G., Cirulli ET., Goldstein DB., Salachas F., Meininger V., Rossoll W., Ratti A., Gellera C., Bosco DA., Bassell GJ., Silani V., Drory VE., Brown RH., Landers JE. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Wu CH., Fallini C., Ticozzi N., Keagle PJ., Sapp PC., Piotrowska K., Lowe P., Koppers M., McKenna-Yasek D., Baron DM., Kost JE., Gonzalez-Perez P., Fox AD., Adams J., Taroni F., Tiloca C., Leclerc AL., Chafe SC., Mangroo D., Moore MJ., Zitzewitz JA., Xu ZS., van den Berg LH., Glass JD., Siciliano G., Cirulli ET., Goldstein DB., Salachas F., Meininger V., Rossoll W., Ratti A., Gellera C., Bosco DA., Bassell GJ., Silani V., Drory VE., Brown RH., Landers JE. DIP original experiment: DIP-250758X Nature 2012 IMEx Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG prof1_human Profilin-1 Profilin I PFN1 Epididymis tissue protein Li 184a protein protein human Homo sapiens Human MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY DIP protein P07737 original sequence version: 73 DIP protein P07737 original sequence version: 160 DIP protein P07737 original sequence version: 97 DIP protein P07737 original sequence version: 98 DIP protein P07737 original sequence version: 168 DIP protein P07737 original sequence version: 140 F725119E55A289EB pfn1-ub-1 1 2 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal mouse Mus musculus Mouse 3 unspecified role unspecified role bait bait P07737:p.Cys71Gly C71G mutation mutation certain certain sequence position certain certain certain sequence position certain C G This feature has been corrected as a result of our quality control procedures. The original label was 'C71G'. Wed May 02 20:06:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys71gly' Tue Jun 30 19:21:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys71Gly' V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range mouse Mus musculus Mouse physical association physical association