DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis. Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis. Proceedings of the National Academy of Sciences of the United States of America 2012 imex curation Dago AE., Schug A., Procaccini A., Hoch JA., Weigt M., Szurmant H. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Dago AE., Schug A., Procaccini A., Hoch JA., Weigt M., Szurmant H. DIP original experiment: DIP-251672X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis. kina_bacsu Sporulation kinase A kinA Stage II sporulation protein F Stage II sporulation protein J gsiC scoD spoIIF spoIIJ BSU13990 protein protein bacsu Bacillus subtilis MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQFLVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGHQSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSKDAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYKNQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFEAATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCIPTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPKK A8BB97FE844B32EE A8BB97FE844B32EE kina-6 1 2 putative self putative self unspecified role unspecified role P16497:p.Glu406Gln E406Q mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain E Q This feature has been corrected as a result of our quality control procedures. The original label was 'E406Q'. Wed May 02 19:42:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu406gln' Tue Jun 30 15:39:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu406Gln' P16497:p.Gln508Glu Q508E mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain Q E This feature has been corrected as a result of our quality control procedures. The original label was 'Q508E'. Wed May 02 16:19:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln508glu' Tue Jun 30 17:36:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln508Glu' P16497:p.Glu448Lys E448K mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E448K'. Wed May 02 18:31:38 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu448lys' Tue Jun 30 19:56:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu448Lys' P16497:p.Gly402Tyr G402Y mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain G Y This feature has been corrected as a result of our quality control procedures. The original label was 'G402Y'. Wed May 02 20:23:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly402tyr' Tue Jun 30 19:26:37 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly402Tyr' P16497:p.Gln505Val Q505V mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain Q V This feature has been corrected as a result of our quality control procedures. The original label was 'Q505V'. Wed May 02 14:56:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln505val' Tue Jun 30 17:04:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln505Val' P16497:p.Pro560Gly P560G mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain P G This feature has been corrected as a result of our quality control procedures. The original label was 'P560G'. Wed May 02 15:12:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro560gly' Tue Jun 30 16:00:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro560Gly' ecolx Escherichia coli phosphorylation phosphorylation reaction phosphorylation true