DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Structure (London, England : 1993) 2012 imex curation Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. Only protein-protein interactions ecolx Escherichia coli tem transmission electron microscopy tem predetermined predetermined participant predetermined Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. DIP original experiment: DIP-249301X Structure (London, England : 1993) 2012 IMEx Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Structure (London, England : 1993) 2012 imex curation Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. DIP original experiment: DIP-249299X Structure (London, England : 1993) 2012 IMEx Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Structure (London, England : 1993) 2012 imex curation Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. Only protein-protein interactions ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. DIP original experiment: DIP-249300X Structure (London, England : 1993) 2012 IMEx Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Architecture of a dodecameric bacterial replicative helicase. Structure (London, England : 1993) 2012 imex curation Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J., Terradot L. DIP original experiment: DIP-249298X Structure (London, England : 1993) 2012 IMEx Architecture of a dodecameric bacterial replicative helicase. dnab_helpy Replicative DNA helicase HP_1362 dnaB protein protein helpy Helicobacter pylori Campylobacter pylori MDHLKHLQQLQNIERIVLSGIVLANHKIEEVHSVLEPSDFYYPPNGLFFEIALKLHEEDCPIDENFIRQKMPKDKQIKEEDLVAIFAASPIDNIEAYVEEIKNASIKRKLFGLANTIREQALESAQKSSDILGAVEREVYALLNGSTIEGFRNIKEVLESAMDLITENQRKGSLEVTGIPTGFVQLDNYTSGFNKGSLVIIGARPSMGKTSLMMNMVLSALNDDRGVAVFSLEMSAEQLALRALSDLTSINMHDLESGRLDDDQWENLAKCFDHLSQKKLFFYDKSYVRIEQIRLQLRKLKSQHKELGIAFIDYLQLMSGSKATKERHEQIAEISRELKTLARELEIPIIALVQLNRSLENRDDKRPILSDIKDSGGIEQDADIVLFLYRGYIYQMRAEDNKIDKLKKEGKIEEAQELYLKVNEERRIHKQNGSIEEAEIIVAKNRNGATGTVYTRFNAPFTRYEDMPIDSHLEEGQETKVDYDIVTT DIP protein O25916 original sequence version: 67 mint Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins 6FF84C2DE4ED606F dnab-4 1 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction dnab-5 4 5 unspecified role unspecified role unspecified role unspecified role C-terminal domain Region 152-488 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction dnab-6 2 5 unspecified role unspecified role unspecified role unspecified role C-terminal domain Region 152-488 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction dnab-7 3 5 unspecified role unspecified role unspecified role unspecified role C-terminal domain Region 152-488 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction