DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions ecolx Escherichia coli pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253950X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253949X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions ecolx Escherichia coli pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253951X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink predetermined predetermined participant predetermined Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253946X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253948X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America 2011 imex curation Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. Only protein-protein interactions ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Zhu J., Yu Y., Ulbrich MH., Li MH., Isacoff EY., Honig B., Yang J. DIP original experiment: DIP-253947X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. q13563-1 Polycystin-2 PKD2 Autosomal dominant polycystic kidney disease type II protein Polycystic kidney disease 2 protein Polycystwin R48321 TRPP2 Transient receptor potential cation channel subfamily P member 2 protein protein human Homo sapiens Human MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV DIP protein Q13563-1 original sequence version: 146 DIP protein Q13563 original sequence version: 144 DIP protein Q13563-1 original sequence version: 128 DIP protein Q13563-1 original sequence version: 133 F8D2E760EBEA8B47 p98161-3 Polycystin-1 PKD1 Autosomal dominant polycystic kidney disease 1 protein protein protein human Homo sapiens Human MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALELVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCYRLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGPAPQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQDAENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASCHPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDAGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTVLLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPTNGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALPWLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAGSDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGKGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSAELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAGTFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPRLALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALMRILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRGPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST DIP protein P98161-3 original sequence version: 165 pkd1_mouse Polycystin-1 Pkd1 Autosomal dominant polycystic kidney disease 1 protein homolog protein protein mouse Mus musculus Mouse MPLGAPALLALALGLGLWLGALAGDPGRGCGPCPLPCFCGPAPDAACRVNCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIGLLVNLSALVELDLSNNRISTLEEGVFANLFNLSEINLSGNPFECNCGLAWLPRWAKEHQVHVVQSEATTCRGPIPLAGQPLLSIPLLDNACGEEYVACLPDNSSGAVAAVPFYFAHEGPLETEACSAFCFSAGEGLAALSEQNQCLCGAGQASNSSAACSSWCSSISLSLNSACGGPTLLQHTFPASPGATLVGPHGPLASGQPADFHITSSLPISSTRWNFGDGSPEVDMASPAATHFYVLPGSYHMTVVLALGAGSALLETEVQVEATPTVLELVCPSFVHSNESLELGIRHRGGSALEVTYSILALDKEPAQVVHPLCPLDTEIFPGNGHCYRLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGTEGLDPRGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWDTENFVMGMSGGGLSGPLHPLAQQETVQGPLRPVEVMVFPGLSPSREAFLTAAEFSTQKLEEPAQMRLQVYRPSGGAAAVPEGSSEPDNRTEPAPKCVPEELWCPGANVCIPFDASCNSHVCINGSVSRLGLSRASYTLWKEFFFSVPAGPPTQYLVTLHSQDVPMLPGDLIGLQHDAGPGTLLQCPLASSCPGQALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTERLTPLLGLGPNPGLQHPGHYEVRATVGNSVSRQNLSCSFSVVSPIAGLRVIHPIPLDGHIYVPTNGSVLVLQVDSGANATATAQWFGGNISAPFEDACPPEVDFLKQDCTEEANGTLFSVLMLPRLKEGDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTVFNVIYQSAAIFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPTVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYTTPGEYNLTVLVSNTYENLTQQVTVSVRTVLPNVAIGMSSNVLVAGQPITFSPYPLPSTDGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGAYRITLEVNNTVSSVTAHADIRVFQELHGLTVYLSPSVEQGAPMVVSASVESGDNITWTFDMGDGTVFTGPEATVQHVYLRAQNFTVTVEAANPAGHLSQSLHVQVFVLEVLHIEPSTCIPTQPSAQLMAHVTGDPVHYLFDWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEIRNITLQPERQFVKLGDEARLVAYSWPPFPYRYTWDFGTEDTTHTQTGGSEVKFIYREPGSYLVIVTVSNNISSTNDSAFVEVQEPVLVTGIRINGSHVLELQQPYLLSAMGSGSPATYLWELGDGSQSEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQFIEGLQVAGGDNGCCFPTNYTLQLQAAVRDGTNISYSWTAQQEGSLITLFGSGKCFSLTSLKASTYYVHLRATNMLGSAAANRTIDFVEPVESLILSASPNPAAVNMSLTLCAELAGGSGVVYTWYLEEGLSWKTSMPSTTHTFAAPGLHLVRVTAENQLGSVNATVEVAIQVPVGGLSIRTSEPDSIFVAAGSTLPFWGQLAEGTNVTWCWTLPGGSKDSQYIAVRFSTAGSFSLQLNASNAVSWVSAMYNLTVEEPIVNLMLWASSKVVAPGQPVHFEILLAAGSALTFRLQVGGSVPEVLPSPHFSHSFFRVGDHLVNVQAENHVSHAQAQVRILVLEAVVGLQVPNCCEPGMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFNELGGVNLTLMVEVQDIIQYVTLQSGRCFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQKTEEFWADHYYLRPGDYHVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEIYRTASCQRPGRMAQMVLPGVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSSVVTIPLERLEAGVEYTFNLIVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSRGYKQGCWAARTFSNKTLVLNETTTSTGSTGMNLVVRPGALRDGEGYIFTLTVLGHSGEEEGCASIRLSPNRPPLGGSCRLFPLDSVRGLTTKVHFECTGWRDAEDGGAPLVYALLLKRCRQSYCENFCIYKGSLSTYGAVLPPGFQPLFVVSLAVVVQDQLGAAVVALNRSLTIVLPEPSGNPADLVPWLHSLTASVLPGLLKQADPQHVIEYSLALITVLNEYEQAPDVSEPNVEQQLRAQMRKNITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQPLELGVEPPSLMVASKAYNLSSALMRILMRSRVLNEEPLTLAGEEIVALGKRSDPLSLLCYGKALGPSCHFSIPEAFSGALSNLSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQSSHNPVGSTIVQPQTSVSAVVTADNSNPQAGLHLRITYTVLNERYLSAEPEPYLAVYLHSVSQPNEYNCSASRRISLEVLEGADHRLYTFFIAPGTGTLDRSYYLNLTSHFHWSALEVSVGLYTSLCQYFSEEMMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEPSASINYIVLLTCVICLVTYVVMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPHSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVRDTTYSMGPVSSLISPGVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDSYLDPSVLDSSLLTLSGLTEAFAGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVVSSTLQRLTQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNLVPTQDTLLETDLLTSLSSVPGEKTETLILQTVGEERPASMGLSWEQSPVTRLSRTGLVEGFQKRLLPAWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDMLKRLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVFLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSSEHMCSAAGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAVFVELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFALYFSMAEVQTWRKDGCACTARPDTWARCLLVILTAATGLVRLAQLGIADRQWTHFVQDHPRHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATLGLVLLGVAYAQMAILLISSGADTLYNMARAFLVLCPGARVPTLCPSESWYLSPLLCVGLWALRVWGALRLGAILLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMDPLPSRSSRGSKSSPVVLPPSSGSEASHPSTSSSQPDGPSASLSRSTLKLEPEPSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLQGHGHNGPPSSPSPGCFPGSQPALPSRLSRASQGLDQTVGPNRVSLWPNNKVHPSST DIP protein O08852 original sequence version: 103 FA12403171DBBCE0 pkd1-pkd2-9 4 8 unspecified role unspecified role unspecified role unspecified role Region 4212-4248 Region 4212-4248 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain P98161-3:p.Val4217Cys V4217C mutation mutation certain certain sequence position certain certain certain sequence position certain V C This feature has been corrected as a result of our quality control procedures. The original label was 'V4217C'. Wed May 02 15:50:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val4217cys' Tue Jun 30 17:20:13 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val4217Cys' MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 7 unspecified role unspecified role unspecified role unspecified role Region 695-968 Region 695-968 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q13563-1:p.Ile860Cys I860C mutation mutation certain certain sequence position certain certain certain sequence position certain I C This feature has been corrected as a result of our quality control procedures. The original label was 'I860C'. Wed May 02 17:29:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860cys' Tue Jun 30 16:36:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Cys' His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction pkd1-pkd2-10 2 9 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range O08852:p.[Leu4229Ala;Glu4230Ala] L4229A/E4230A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain E A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4229A/E4230A'. Wed May 02 14:27:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4229ala,glu4230ala' Tue Jun 30 18:29:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4229Ala;Glu4230Ala]' O08852:p.[Leu4229Ala;Leu4233Ala] L4229A/L4233A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4229A/L4233A'. Wed May 02 17:11:25 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4229ala,leu4233ala' Tue Jun 30 17:43:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4229Ala;Leu4233Ala]' human Homo sapiens Human 7 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association pkd2-pkd1-4 3 8 unspecified role unspecified role prey prey MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 4212-4248 Region 4212-4248 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 7 unspecified role unspecified role bait bait Region 695-968 Region 695-968 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q13563-1:p.[Asp861Ala;Ile864Ala;Val865Ala] D861A/I864A/V865A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain V A certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain D A This feature has been corrected as a result of our quality control procedures. The original label was 'D861A/I864A/V865A'. Wed May 02 16:59:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp861ala,ile864ala,val865ala' Tue Jun 30 18:36:45 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asp861Ala;Ile864Ala;Val865Ala]' Q13563-1:p.[Val865Ala;Ile869Ala] V865A/I869A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V865A/I869A'. Wed May 02 15:38:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val865ala,ile869ala' Tue Jun 30 18:15:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val865Ala;Ile869Ala]' Q13563-1:p.[Lys876Ala;Arg877Ala] K876A/R877A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain K A This feature has been corrected as a result of our quality control procedures. The original label was 'K876A/R877A'. Wed May 02 17:09:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys876ala,arg877ala' Tue Jun 30 16:49:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys876Ala;Arg877Ala]' Q13563-1:p.[Lys876Ala;Arg877Ala;Arg878Ala;Glu879Ala] K876A/R877A/R878A/E879A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain E A certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain K A This feature has been corrected as a result of our quality control procedures. The original label was 'K876A/R877A/R878A/E879A'. Wed May 02 20:33:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys876ala,arg877ala,arg878ala,glu879ala' Tue Jun 30 19:05:10 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys876Ala;Arg877Ala;Arg878Ala;Glu879Ala]' Q13563-1:p.[Lys876Gly;Arg877Gly;Arg878Gly;Glu879Gly] K876G/R877G/R878G/E879G mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain E G certain certain sequence position certain certain certain sequence position certain R G certain certain sequence position certain certain certain sequence position certain R G certain certain sequence position certain certain certain sequence position certain K G This feature has been corrected as a result of our quality control procedures. The original label was 'K876G/R877G/R878G/E879G'. Wed May 02 19:17:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys876gly,arg877gly,arg878gly,glu879gly' Tue Jun 30 18:56:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys876Gly;Arg877Gly;Arg878Gly;Glu879Gly]' Q13563-1:p.[Arg877Ala;Arg878Ala] R877A/R878A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain R A This feature has been corrected as a result of our quality control procedures. The original label was 'R877A/R878A'. Wed May 02 18:33:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg877ala,arg878ala' Tue Jun 30 20:09:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg877Ala;Arg878Ala]' Q13563-1:p.[Arg877Gly;Arg878Gly] R877G/R878G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain R G certain certain sequence position certain certain certain sequence position certain R G This feature has been corrected as a result of our quality control procedures. The original label was 'R877G/R878G'. Wed May 02 15:43:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg877gly,arg878gly' Tue Jun 30 20:25:34 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg877Gly;Arg878Gly]' Q13563-1:p.[Val880Ala;Leu881Ala;Leu885Ala] V880A/L881A/L885A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V880A/L881A/L885A'. Wed May 02 18:21:36 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val880ala,leu881ala,leu885ala' Tue Jun 30 19:31:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val880Ala;Leu881Ala;Leu885Ala]' Q13563-1:p.[Leu881Ala;Leu885Ala] L881A/L885A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L881A/L885A'. Wed May 02 16:08:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu881ala,leu885ala' Tue Jun 30 19:34:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu881Ala;Leu885Ala]' Q13563-1:p.[Leu881Asp;Leu885Asp] L881D/L885D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L D certain certain sequence position certain certain certain sequence position certain L D This feature has been corrected as a result of our quality control procedures. The original label was 'L881D/L885D'. Wed May 02 16:09:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu881asp,leu885asp' Tue Jun 30 17:18:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu881Asp;Leu885Asp]' Q13563-1:p.[Arg883Ala;Leu884Ala] R883A/L884A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain R A This feature has been corrected as a result of our quality control procedures. The original label was 'R883A/L884A'. Wed May 02 19:40:28 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg883ala,leu884ala' Tue Jun 30 17:41:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg883Ala;Leu884Ala]' ecolx Escherichia coli physical association physical association pkd1-pkd2-11 5 9 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 7 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q13563-1:p.[Leu881Ala;Leu885Ala] L881A/L885A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L881A/L885A'. Wed May 02 17:26:11 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu881ala,leu885ala' Tue Jun 30 17:07:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu881Ala;Leu885Ala]' Q13563-1:p.[Val880Ala;Leu881Ala;Leu885Ala] V880A/L881A/L885A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V880A/L881A/L885A'. Wed May 02 18:07:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val880ala,leu881ala,leu885ala' Tue Jun 30 19:32:23 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val880Ala;Leu881Ala;Leu885Ala]' human Homo sapiens Human physical association physical association pkd2-pkd1-5 1 8 unspecified role unspecified role prey prey Region 4212-4248 Region 4212-4248 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P98161-3:p.[Val4217Ala;Leu4228Ala] V4217A/L4228A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain V A This feature has been corrected as a result of our quality control procedures. The original label was 'V4217A/L4228A'. Wed May 02 18:11:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val4217ala,leu4228ala' Tue Jun 30 18:28:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val4217Ala;Leu4228Ala]' P98161-3:p.[Phe4225Ala;Arg4227Ala] F4225A/R4227A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F4225A/R4227A'. Wed May 02 18:24:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe4225ala,arg4227ala' Tue Jun 30 16:10:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe4225Ala;Arg4227Ala]' P98161-3:p.[Phe4225Ala;Leu4228Ala] F4225A/L4228A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F4225A/L4228A'. Wed May 02 14:44:09 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe4225ala,leu4228ala' Tue Jun 30 16:50:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe4225Ala;Leu4228Ala]' P98161-3:p.[Leu4228Ala;Asn4229Ala] L4228A/N4229A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain N A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4228A/N4229A'. Wed May 02 15:24:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4228ala,asn4229ala' Tue Jun 30 16:40:05 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4228Ala;Asn4229Ala]' P98161-3:p.Asp4234Arg D4234R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain D R This feature has been corrected as a result of our quality control procedures. The original label was 'D4234R'. Wed May 02 18:15:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp4234arg' Tue Jun 30 19:46:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asp4234Arg' P98161-3:p.Tyr4236Arg Y4236R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain Y R This feature has been corrected as a result of our quality control procedures. The original label was 'Y4236R'. Wed May 02 15:23:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr4236arg' Tue Jun 30 19:30:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr4236Arg' P98161-3:p.[Asp4234Ala;Tyr4236Ala] D4234A/Y4236A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain Y A certain certain sequence position certain certain certain sequence position certain D A This feature has been corrected as a result of our quality control procedures. The original label was 'D4234A/Y4236A'. Wed May 02 14:30:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp4234ala,tyr4236ala' Tue Jun 30 16:50:42 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asp4234Ala;Tyr4236Ala]' P98161-3:p.Leu4238Ala L4238A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4238A'. Wed May 02 15:03:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4238ala' Tue Jun 30 18:46:25 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu4238Ala' P98161-3:p.[Leu4238Ala;Glu4239Ala] L4238A/E4239A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain E A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4238A/E4239A'. Wed May 02 17:28:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4238ala,glu4239ala' Tue Jun 30 19:24:29 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4238Ala;Glu4239Ala]' P98161-3:p.[Leu4238Ala;Leu4242Ala] L4238A/L4242A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4238A/L4242A'. Wed May 02 19:02:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4238ala,leu4242ala' Tue Jun 30 20:24:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4238Ala;Leu4242Ala]' P98161-3:p.[Leu4238Ala;Leu4242Ala;Leu4245Ala] L4238A/L4242A/L4245A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L4238A/L4242A/L4245A'. Wed May 02 15:16:25 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu4238ala,leu4242ala,leu4245ala' Tue Jun 30 18:00:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu4238Ala;Leu4242Ala;Leu4245Ala]' ecolx Escherichia coli 7 unspecified role unspecified role bait bait Region 695-968 Region 695-968 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association pkd1-pkd2-12 6 8 unspecified role unspecified role bait bait Region 4212-4248 Region 4212-4248 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 7 unspecified role unspecified role prey prey Region 695-968 Region 695-968 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association