DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu A redox switch in angiotensinogen modulates angiotensin release. A redox switch in angiotensinogen modulates angiotensin release. Nature 2010 imex curation Zhou A., Carrell RW., Murphy MP., Wei Z., Yan Y., Stanley PL., Stein PE., Broughton Pipkin F., Read RJ. Only protein-protein interactions in vitro In vitro protease assay protease assay predetermined predetermined participant predetermined Zhou A., Carrell RW., Murphy MP., Wei Z., Yan Y., Stanley PL., Stein PE., Broughton Pipkin F., Read RJ. DIP original experiment: DIP-219281X Nature 2010 IMEx A redox switch in angiotensinogen modulates angiotensin release. A redox switch in angiotensinogen modulates angiotensin release. A redox switch in angiotensinogen modulates angiotensin release. Nature 2010 imex curation Zhou A., Carrell RW., Murphy MP., Wei Z., Yan Y., Stanley PL., Stein PE., Broughton Pipkin F., Read RJ. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Zhou A., Carrell RW., Murphy MP., Wei Z., Yan Y., Stanley PL., Stein PE., Broughton Pipkin F., Read RJ. DIP original experiment: DIP-219282X Nature 2010 IMEx A redox switch in angiotensinogen modulates angiotensin release. angt_human Angiotensinogen Serpin A8 AGT SERPINA8 protein protein human Homo sapiens Human MRKRAPQSEMAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA DIP protein P01019 original sequence version: 136 5026C2DFB2DD236E reni_human Renin Angiotensinogenase REN protein protein human Homo sapiens Human MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR DIP protein P00797 original sequence version: 141 5AFDF8E973B21EDA agt-ren-1 1 3 enzyme target enzyme target substrate substrate unspecified role unspecified role ecolx Escherichia coli 4 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli protein cleavage protein cleavage agt-ren-2 2 3 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction