DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Nature 2010 imex curation Guang S., Bochner AF., Burkhart KB., Burton N., Pavelec DM., Kennedy S. Only protein-protein interactions caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Guang S., Bochner AF., Burkhart KB., Burton N., Pavelec DM., Kennedy S. DIP original experiment: DIP-219469X Nature 2010 IMEx Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Nature 2010 imex curation Guang S., Bochner AF., Burkhart KB., Burton N., Pavelec DM., Kennedy S. Only protein-protein interactions caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Guang S., Bochner AF., Burkhart KB., Burton N., Pavelec DM., Kennedy S. DIP original experiment: DIP-219470X Nature 2010 IMEx Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. nrde3_caeel Nuclear RNAi defective-3 protein nrde-3 R04A9.2 protein protein caeel Caenorhabditis elegans MDLLDKVMGEMGSKPGSTAKKPATSASSTPRTNVWGTAKKPSSQQQPPKPLFTTPGSQQGSLGGRIPKREHTDRTGPDPKRKPLGGLSVPDSFNNFGTFRVQMNAWNLDISKMDERISRIMFRATLVHTDGRRFELSLGVSAFSGDVNRQQRRQAQCLLFRAWFKRNPELFKGMTDPAIAAYDAAETIYVGCSFFDVELTEHVCHLTEADFSPQEWKIVSLISRRSGSTFEIRIKTNPPIYTRGPNALTLENRSELTRIIEAITDQCLHNEKFLLYSSGTFPTKGGDIASPDEVTLIKSGFVKTTKIVDRDGVPDAIMTVDTTKSPFYKDTSLLKFFTAKMDQLTNSGGGPRGHNGGRERRDGGGNSRKYDDRRSPRDGEIDYDERTVSHYQRQFQDERISDGMLNTLKQSLKGLDCQPIHLKDSKANRSIMIDEIHTGTADSVTFEQKLPDGEMKLTSITEYYLQRYNYRLKFPHLPLVTSKRAKCYDFYPMELMSILPGQRIKQSHMTVDIQSYMTGKMSSLPDQHIKQSKLVLTEYLKLGDQPANRQMDAFRVSLKSIQPIVTNAHWLSPPDMKFANNQLYSLNPTRGVRFQTNGKFVMPARVKSVTIINYDKEFNRNVDMFAEGLAKHCSEQGMKFDSRPNSWKKVNLGSSDRRGTKVEIEEAIRNGVTIVFGIIAEKRPDMHDILKYFEEKLGQQTIQISSETADKFMRDHGGKQTIDNVIRKLNPKCGGTNFLIDVPESVGHRVVCNNSAEMRAKLYAKTQFIGFEMSHTGARTRFDIQKVMFDGDPTVVGVAYSLKHSAQLGGFSYFQESRLHKLTNLQEKMQICLNAYEQSSSYLPETVVVYRVGSGEGDYPQIVNEVNEMKLAARKKKHGYNPKFLVICTQRNSHIRVFPEHINERGKSMEQNVKSGTCVDVPGASHGYEEFILCCQTPLIGTVKPTKYTIIVNDCRWSKNEIMNVTYHLAFAHQVSYAPPAIPNVSYAAQNLAKRGHNNYKTHTKLVDMNDYSYRIKEKHEEIISSEEVDDILMRDFIETVSNDLNAMTINGRNFWA DIP protein Q21691 original sequence version: 57 C86F4A37DE64F519 nrde2_caeel Nuclear exosome regulator NRDE2 Nuclear RNAi defective-2 protein T01E8.5 nrde-2 protein protein caeel Caenorhabditis elegans MFRAYGNNGLKNPERISGENPDLYTQTRAAVQQRATTTLKRNEKQKLAVQNDSVFQQVGIGESDSDDDNGGVRIRMSPHRYIDPDDVFTLPEVKKQNALRDAKIAARAAQATAYNTFPSVKSLNGCQDPPETSQQSTSRKRSASNSRSPSRSHSRRYDRDNGRQRSRSREKKRRKKERRRKRSSSRSSSSSRSRDRSSRARDTSSHTLMKMNKPAKYAFLTDEEYRTCDAYISSAFITQTKSDCENYTQGVPKKEIAKCRLSVKFIVGLEHNNILFNNIYGAEYARDKENRPFWEQLDRYLKDVPKETFFRYVPPVGGYWKIRDRVDLLNLDHIDDDVLANDSDNRKDAFTFELEQAKKTFSENVHNIDALIKVISMEEEMCRRNVGSFSSSNPAALAERHQEMVKKAIKADGRNAKLRLMKIELLIKMDPNSPTIIDDFKNLTITFPHEPMVWIKYLDYIQYDSNVYNYKKLKNAFEDCIRQVTGLTNGTLLSHLNAVNDRPLLRMFHLWIYIRYLKWMISCAHTPVVLANIQATFEYNFGLADVEKRTSTNSKEREVRLEEFWESGLPRIGDEGAVGAEKMLKQSEELSDEDIQKLENDDFDILISRTEETIATCLQAQRDVQISWIEVEREMMNIDARVKRTKLKDCELYEDHVDDLETCELWDIIPFDRIRYYEAPGDCANFDFVQPFLELLGVKFLNSTNCFTTTEQIISDWISNDSTVNFYKTPTYTEKKCFEVGNNILKFMLYNRLKLTENNPEYLDKTMVKYLLAMLVTEASEQEKKLNFHSFKLNLKNLVGTFITKHPDIFKRAMLSKITGIVYMEKFVSWWERALKEQEKVVEADERRKNYKEIKMEEGVVDDVKFDVILLKKDKERVQTIRDKIRDMIDIAIPKSTEKLIQSADSSLPTLQLHLYANVLRGRLSILNQNALEETRDVFCKEILGIHTSEFESDEALLLALDQGLNELLEHCKEKDNLESVDSIPELPRAEALCEALKVVAVFVFLDKMAFSRRAVDCLIANAITKFEQFEAKKNDFNRGTYEKYCDQIDLKFITDTLITFFSHKKHRFIYNENFKKLIFQASQAFPCDSKYAKMLGELHSSGRLQVMKLQGFTDSRNSILNAKRDQQFDPELETRLLMNSLTIMFSWMNAANRIGDAGNQILYKNWKREAANTRDPAIWRQVIRVASKLSQKILKDDAYTRARGQCTWALNLHFDYIEAKTVRKNGDLMEMIYLILEQSMGQEHSLFVTDEEYMKTQQEIGLQYSESGR DCB661227D75F541 nrde_3-nrde2-1 1 4 unspecified role unspecified role prey prey caeel Caenorhabditis elegans 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q21691:p.[Lys80Ala;Arg81Ala;Lys82Ala] K80A/R81A/K82A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain K A certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain K A This feature has been corrected as a result of our quality control procedures. The original label was 'K80A/R81A/K82A'. Wed May 02 15:19:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys80ala,arg81ala,lys82ala' Tue Jun 30 17:11:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys80Ala;Arg81Ala;Lys82Ala]' caeel Caenorhabditis elegans physical association physical association nrde2-nrde_3-1 2 4 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range caeel Caenorhabditis elegans 3 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range caeel Caenorhabditis elegans physical association physical association