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          <fullName>Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.</fullName>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HVV" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J7P" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J7Q" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UMJ" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UMK" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UZY" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V70" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V73" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XEJ" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CA7" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6B1C" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6B1K" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6B2C" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BG6" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BG7" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CB5" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CBF" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CBG" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FVE" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FVH" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OY8" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OYB" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OYE" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OYG" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PEG" version="SP_237"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202733" version="SP_237"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_237"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8950505" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CBH" version="SP_237"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-31137N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P14174 original sequence version: 138</attribute>
          <attribute name="remark-internal">DIP protein P14174 original sequence version: 186</attribute>
          <attribute name="crc64">56D51107C05286B2</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-16430-1">
        <names>
          <shortLabel>mif-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-187642E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15858465" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16430-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="6" imexId="IM-16430-2">
        <names>
          <shortLabel>mif-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-187642E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15858483" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16430-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>