DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220825X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220830X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220833X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220826X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220824X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions in vitro In vitro pull down pull down autoradiography autoradiography Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220837X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220831X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220832X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions in vitro In vitro pull down pull down autoradiography autoradiography Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220839X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220835X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220840X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220836X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220828X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220827X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220829X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220834X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. Only protein-protein interactions in vitro In vitro pull down pull down autoradiography autoradiography Hou Z., Peng H., White DE., Negorev DG., Maul GG., Feng Y., Longmore GD., Waxman S., Zelent A., Rauscher FJ. DIP original experiment: DIP-220838X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. rxrg_human Retinoic acid receptor RXR-gamma Retinoid X receptor gamma Nuclear receptor subfamily 2 group B member 3 RXRG NR2B3 protein protein human Homo sapiens Human MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT DIP protein P48443 original sequence version: 124 AED5C94BB62A3157 limd1_mouse LIM domain-containing protein 1 Limd1 protein protein mouse Mus musculus Mouse MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPVNGGNRQGASGKLAADGAAKPPLAVPTVAPGLATTTAAAQPSYPSQEQRIRPSAHGARPGSQNCGSREGPVSSQRPALHGLSPSCEDPSCLTHGDYYDNFSLASPQWGDKPEGCPSVSLGVGSGWPGCPGNDSTLPKSCGDHHPYQPQLSTVCSGRSFESGISGQDGGIGGHSSEKPTGLWSTASSQRVNLGFSSMGLENGTSAQPKGTTVSAPMVPSSASQGACPKRDSGLGYEASGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTAGKDSTQPGMTTGLDPKFGCVESGTSPKPSPTSNVHPVMSTPSELSCKESSPSWSTDSSLEPVLPGSPTPSRVRLPCQTLAPGPELGPSTAELKLEALTQRLEREMDAHPKADYFGSCVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPAPLHQHHF DIP protein Q9QXD8 original sequence version: 85 68C05A7BADEBDC92 wtip_mouse Wilms tumor protein 1-interacting protein Wtip protein protein mouse Mus musculus Mouse MQRSRTAADDAALLLAGLGLRESEPTAGSPGRVRRGPRAVDEAAPASGRRGKGGCGGPEAAPDVPSRPERGPRASLAGSDGGSARSSGISLGYDQRHGPGPGPPSGGSARSSVSSLGSRGSAGACADLLPPGVGPAPARSPEPAQFPFPLPSLPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGARQACQAMGSLYHTDCFICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVDNNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVECYHCEDCGLQLSGEEGRRCYPLEGHLLCRRCHLRRLGQGPLPSPAVHVTEL DIP protein Q7TQJ8 original sequence version: 65 mint homomint 6677EE0A882D1E40 rarg_mouse Retinoic acid receptor gamma Rarg Nr1b3 Nuclear receptor subfamily 1 group B member 3 protein protein mouse Mus musculus Mouse MATNKERLFAPGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSKPGPHPKASSEDEAPGGQGKRGQSPQPDQGP DIP protein P18911 original sequence version: 128 This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression mint 1D13D2F1482D7194 tha_mouse Thyroid hormone receptor alpha Thra C-erba-alpha Nr1a1 Nuclear receptor subfamily 1 group A member 1 c-erbA-1 c-erbA-alpha protein protein mouse Mus musculus Mouse MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLRGPVLQHQSPKSPQQRLLELLHRSGILHSRAVCGEDDSSEASSLSSSSDTEDTEVCEDQAGKAASP DIP protein P63058 original sequence version: 117 DIP protein P63058 original sequence version: 89 mint Nuclear hormone receptor. High affinity receptor for triiodothyronine 870100FCB5C34A10 rara_human Retinoic acid receptor alpha RARA NR1B1 Nuclear receptor subfamily 1 group B member 1 protein protein human Homo sapiens Human MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP DIP protein P10276 original sequence version: 190 DIP protein P10276 original sequence version: 118 DIP protein P10276 original sequence version: 162 DIP protein P10276-1 original sequence version: 143 DIP protein P10276 original sequence version: 200 DIP protein P10276-1 original sequence version: 152 E8D1CF9A1E57CB99 rara_mouse Retinoic acid receptor alpha Rara Nr1b1 Nuclear receptor subfamily 1 group B member 1 protein protein mouse Mus musculus Mouse MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTSLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFDVGMSKESVRNDRNKKKKEAPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDKVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQSGGGTRDGGGLAPPPGSCSPSLSPSSHRSSPATQSP DIP protein P11416 original sequence version: 140 726F7799633A85AD anm5_human Protein arginine N-methyltransferase 5 PRMT5 IBP72 JBP1 HRMT1L5 Shk1 kinase-binding protein 1 homolog Jak-binding protein 1 72 kDa ICln-binding protein SKB1 Histone-arginine N-methyltransferase PRMT5 protein protein human Homo sapiens Human MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL DIP protein O14744 original sequence version: 86 DIP protein O14744 original sequence version: 104 DIP protein O14744-1 original sequence version: 148 DIP protein O14744-1 original sequence version: 114 DIP protein O14744 original sequence version: 146 522E255B384F25E7 ajuba_mouse LIM domain-containing protein ajuba Ajuba Jub protein protein mouse Mus musculus Mouse MERLGEKASRLLEKLRLSDSGSAKFGRRKGEASRSGSDGTPGAGKGRLSGLGGPRKSGHRGANGGPGDEPLEPAREQGPLDAERNARGSFEAQRFEGSFPGGPPPTRALPLPLSSPPDFRLETTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGASGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGLPLTTAPAGYPGGAPSAYPELHAALDRLCAHRSVGFGCQESRHSYPPALGSPGALTGAVVGTAGPLERRGAQPGRHSVTGYGDCAAGARYQDELTALLRLTVATGGREAGARGEPSGIEPSGLEESPGPFVPEASRSRIREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLSARQPSTNYI DIP protein Q91XC0 original sequence version: 32 DIP protein Q91XC0 original sequence version: 65 C326772AC1C155B2 ajuba-rara-1 11 23 unspecified role unspecified role unspecified role unspecified role Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role unspecified role unspecified role Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association rara-ajuba-1 5 24 unspecified role unspecified role bait bait mouse Mus musculus Mouse 26 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association rara-wtip-1 8 20 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 23 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-prmt5-1 12 25 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-thra-1 15 22 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-rara-2 1 23 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-rara-3 9 23 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 26 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 244-350 Region 244-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction rarg-ajuba-1 3 21 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-prmt5-2 6 25 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 23 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 26 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 244-350 Region 244-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli association association rara-ajuba-2 2 23 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q91XC0:p.[Leu292Ala;Leu293Ala;Leu295Ala;Leu418Ala;Ile419Ala;Leu420Ala;Ile488Ala;Val489Ala;Val491Ala] L292A/L293A/L295A/L418A/I419A/L420L/I488A/V489A/V491A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain V A certain certain sequence position certain certain certain sequence position certain V A certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L292A/L293A/L295A/L418A/I419A/L420L/I488A/V489A/V491A'. Tue Jun 30 20:00:07 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu292Ala;Leu293Ala;Leu295Ala;Leu418Ala;Ile419Ala;Leu420Ala;Ile488Ala;Val489Ala;Val491Ala]' human Homo sapiens Human physical association physical association rara-ajuba-3 4 23 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 26 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro direct interaction direct interaction ajuba-prmt5-3 17 25 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 26 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 244-350 Region 244-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction rxrg-ajuba-1 16 18 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-rarg-1 14 21 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association rara-limd1-1 7 19 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 23 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association ajuba-prmt5-4 10 25 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 23 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human association association ajuba-rxrg-1 13 18 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 26 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association