DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure (London, England : 1993) 2009 imex curation Oda S., Schröder M., Khan AR. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Oda S., Schröder M., Khan AR. DIP original experiment: DIP-131973X Structure (London, England : 1993) 2009 IMEx Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure (London, England : 1993) 2009 imex curation Oda S., Schröder M., Khan AR. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Oda S., Schröder M., Khan AR. DIP original experiment: DIP-131971X Structure (London, England : 1993) 2009 IMEx Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure (London, England : 1993) 2009 imex curation Oda S., Schröder M., Khan AR. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Oda S., Schröder M., Khan AR. DIP original experiment: DIP-131972X Structure (London, England : 1993) 2009 IMEx Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure (London, England : 1993) 2009 imex curation Oda S., Schröder M., Khan AR. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Oda S., Schröder M., Khan AR. DIP original experiment: DIP-131974X Structure (London, England : 1993) 2009 IMEx Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure (London, England : 1993) 2009 imex curation Oda S., Schröder M., Khan AR. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Oda S., Schröder M., Khan AR. DIP original experiment: DIP-131975X Structure (London, England : 1993) 2009 IMEx Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. ddx3x_human ATP-dependent RNA helicase DDX3X DDX3X DBX DDX3 DEAD box protein 3, X-chromosomal Helicase-like protein 2 DEAD box, X isoform CAP-Rf protein protein human Homo sapiens Human MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN DIP protein O00571 original sequence version: 116 DIP protein O00571 original sequence version: 123 7074D2B8A6EBBF09 k7_vaccw Protein K7 K7R VACWR039 protein protein vaccw vaccinia virus (stra Vaccinia virus (strain WR) VACV MATKLDYEDAVFYFVDDDKICSRDSIIDLIDEYITWRNHVIVFNKDITSCGRLYKELMKFDDVAIRYYGIDKINEIVEAMSEGDHYINFTKVHDQESLFATIGICAKITEHWGYKKISESRFQSLGNITDLMTDDNINILILFLEKKLN DIP protein P68466 original sequence version: 22 B3E972A93DF97DC8 ddx3x-k7_vaccw-1 2 6 unspecified role unspecified role bait bait Region 71-90 Region 71-90 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range in vitro In vitro 7 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction ddx3x-k7_vaccw-2 1 6 unspecified role unspecified role unspecified role unspecified role Region 71-90 Region 71-90 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain O00571:p.[Phe84Ala;Phe85Ala] F84A/F85A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F84A/F85A'. Wed May 02 15:47:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe84ala,phe85ala' Tue Jun 30 16:47:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe84Ala;Phe85Ala]' in vitro In vitro 7 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction ddx3x-k7_vaccw-3 5 6 unspecified role unspecified role unspecified role unspecified role Region 5-167 Region 5-167 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 7 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction ddx3x-k7_vaccw-4 3 6 unspecified role unspecified role unspecified role unspecified role Region 71-90 Region 71-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro 7 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction ddx3x-k7_vaccw-5 4 6 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range O00571:p.[Phe84Ala;Phe85Ala] F84A/F85A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F84A/F85A'. Wed May 02 16:49:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe84ala,phe85ala' Tue Jun 30 19:04:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe84Ala;Phe85Ala]' human Homo sapiens Human 7 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association