DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. Only protein-protein interactions human Homo sapiens Human comigration in sds comigration in sds page comigration in sds western blot western blot Immuno blot Immuno blot Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. DIP original experiment: DIP-68509X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. DIP original experiment: DIP-68505X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. DIP original experiment: DIP-68507X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. DIP original experiment: DIP-68506X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Unk I., Hajdú I., Fátyol K., Hurwitz J., Yoon JH., Prakash L., Prakash S., Haracska L. DIP original experiment: DIP-68508X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG ube2n_human Ubiquitin-conjugating enzyme E2 N Ubiquitin-protein ligase N Ubiquitin carrier protein N Ubc13 Bendless-like ubiquitin-conjugating enzyme UBE2N BLU UbcH13 E2 ubiquitin-conjugating enzyme N protein protein human Homo sapiens Human MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI DIP protein P61088 original sequence version: 137 DIP protein P61088 original sequence version: 105 DIP protein P61088 original sequence version: 60 DIP protein P61088 original sequence version: 64 DIP protein P61088 original sequence version: 85 FACD84D883D77407 hltf_human Helicase-like transcription factor SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 Sucrose nonfermenting protein 2-like 3 DNA-binding protein/plasminogen activator inhibitor 1 regulator HIP116 RING finger protein 80 HLTF HIP116A RNF80 SNF2L3 ZBU1 SMARCA3 RING-type E3 ubiquitin transferase HLTF protein protein human Homo sapiens Human MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTSDEEVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKTLGFNLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLFEDLKEDDKTHEMEPAEAIETPLLPHQKQALAWMVSRENSKELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLGKTLTAIAVILTNFHDGRPLPIERVKKNLLKKEYNVNDDSMKLGGNNTSEKADGLSKDASRCSEQPSISDIKEKSKFRMSELSSSRPKRRKTAVQYIESSDSEEIETSELPQKMKGKLKNVQSETKGRAKAGSSKVIEDVAFACALTSSVPTTKKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIREPALLSKQDIVLTTYNILTHDYGTKGDSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMGDEGGLRRLQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSDEERKIYQSVKNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLECPPEELARDSEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL DIP protein Q14527 original sequence version: 67 DIP protein Q14527 original sequence version: 69 0AB96F6C8484FD15 ub2v2_human Ubiquitin-conjugating enzyme E2 variant 2 MMS2 homolog Enterocyte differentiation-associated factor 1 Enterocyte differentiation-promoting factor 1 Vitamin D3-inducible protein DDVit 1 UBE2V2 MMS2 UEV2 protein protein human Homo sapiens Human MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN DIP protein Q15819 original sequence version: 137 DIP protein Q15819 original sequence version: 69 98D632A1AEC0AADE ube2b_human Ubiquitin-conjugating enzyme E2 B Ubiquitin-protein ligase B Ubiquitin carrier protein B RAD6 homolog B Ubiquitin-conjugating enzyme E2-17 kDa UBE2B RAD6B E2 ubiquitin-conjugating enzyme B protein protein human Homo sapiens Human MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS DIP protein P63146 original sequence version: 115 DIP protein P63146 original sequence version: 51 DIP protein P63146 original sequence version: 79 DIP protein P63146 original sequence version: 101 CFDEEEE7E06840BE rad18_human E3 ubiquitin-protein ligase RAD18 RAD18 RNF73 Postreplication repair protein RAD18 RING finger protein 73 RING-type E3 ubiquitin transferase RAD18 protein protein human Homo sapiens Human MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRAAESAEIEPRNKRNRN DIP protein Q9NS91 original sequence version: 129 DIP protein Q9NS91 original sequence version: 62 DIP protein Q9NS91 original sequence version: 64 DIP protein Q9NS91 original sequence version: 114 744A053A50C65DD7 pcna_human Proliferating cell nuclear antigen PCNA Cyclin protein protein human Homo sapiens Human MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS DIP protein P12004 original sequence version: 200 DIP protein P12004 original sequence version: 128 DIP protein P12004 original sequence version: 139 DIP protein P12004 original sequence version: 185 DIP protein P12004 original sequence version: 102 DIP protein P12004 original sequence version: 105 DIP protein P12004 original sequence version: 158 E6F08E7EDBC48B00 hltf-pcna-1 2 11 unspecified role unspecified role prey prey ha tag ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 9 unspecified role unspecified role prey prey ha tag ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 7 unspecified role unspecified role prey prey ha tag ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 12 unspecified role unspecified role prey prey ha tag ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 8 unspecified role unspecified role bait bait Flag tag Flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human association association hltf-rad18-1 4 7 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 9 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 11 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 10 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 8 unspecified role unspecified role bait bait Gst tag Gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast association association ub-pcna-2 5 12 unspecified role unspecified role prey prey ha tag ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 6 unspecified role unspecified role bait bait his tag his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag predetermined featur predetermined feature predetermined featur n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal human Homo sapiens Human physical association physical association pcna-ub-1 3 6 unspecified role unspecified role prey prey human Homo sapiens Human 12 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association pcna-ub-2 1 6 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human 12 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human covalent binding covalent binding