<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18042724" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0705147104" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15672563" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-9257" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis.</attribute>
            <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Miya A.,  Albert P.,  Shinya T.,  Desaki Y.,  Ichimura K.,  Shirasu K.,  Narusaka Y.,  Kawakami N.,  Kaku H.,  Shibuya N.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-9257" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-68780X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="18042724" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0705147104" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>protein kinase assay</shortLabel>
            <fullName>protein kinase assay</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0424" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608517" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>weight autoradiogra</shortLabel>
            <fullName>molecular weight estimation by autoradiography</fullName>
            <alias type="synonym" typeAc="MI:1041">weight autoradiogra</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0821" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218638" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Miya A., Albert P., Shinya T., Desaki Y., Ichimura K., Shirasu K., Narusaka Y., Kawakami N., Kaku H., Shibuya N.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68780X</attribute>
          <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>mbp_bovin</shortLabel>
          <fullName>Myelin basic protein</fullName>
          <alias type="gene name" typeAc="MI:0301">MBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Myelin A1 protein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">20 kDa microtubule-stabilizing protein</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P02687" version="SP_70" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BGM8" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9TS63" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9TSA6" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-908215" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P02687"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29967N"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005543" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019911" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033269" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042552" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043209" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043218" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071944" version="SP_148"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000548" version="SP_148"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" version="SP_148"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9913">
          <names>
            <shortLabel>bovin</shortLabel>
            <fullName>Bos taurus (Bovine)</fullName>
            <alias type="synonym" typeAc="MI:1041">Bovine</alias>
          </names>
        </organism>
        <sequence>AAQKRPSQRSKYLASASTMDHARHGFLPRHRDTGILDSLGRFFGSDRGAPKRGSGKDGHHAARTTHYGSLPQKAQGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRASDYKSAHKGLKGHDAQGTLSKIFKLGGRDSRSGSPMARR</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P02687 original sequence version: 75</attribute>
          <attribute name="crc64">8E1157B7A1978484</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>cerk1_arath</shortLabel>
          <fullName>Chitin elicitor receptor kinase 1</fullName>
          <alias type="gene name" typeAc="MI:0301">CERK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">LYK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">LysM domain receptor-like kinase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RLK1</alias>
          <alias type="orf name" typeAc="MI:0306">MIL23.20</alias>
          <alias type="locus name" typeAc="MI:0305">At3g21630</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="A8R7E6" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9LVE3" version="SP_91" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_566689" version="2" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29970N" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15672582" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035556"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043621"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071219"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071323"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002752"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004675"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005622"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001080"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008061"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009817"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016301"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032491"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032499"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010200"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001245"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018392"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EBY"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EBZ"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_566689.2"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036779"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="3702">
          <names>
            <shortLabel>arath</shortLabel>
            <fullName>Arabidopsis thaliana (Mouse-ear cress)</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse-ear cress</alias>
          </names>
        </organism>
        <sequence>MKLKISLIAPILLLFSFFFAVESKCRTSCPLALASYYLENGTTLSVINQNLNSSIAPYDQINFDPILRYNSNIKDKDRIQMGSRVLVPFPCECQPGDFLGHNFSYSVRQEDTYERVAISNYANLTTMESLQARNPFPATNIPLSATLNVLVNCSCGDESVSKDFGLFVTYPLRPEDSLSSIARSSGVSADILQRYNPGVNFNSGNGIVYVPGRDPNGAFPPFKSSKQDGVGAGVIAGIVIGVIVALLLILFIVYYAYRKNKSKGDSFSSSIPLSTKADHASSTSLQSGGLGGAGVSPGIAAISVDKSVEFSLEELAKATDNFNLSFKIGQGGFGAVYYAELRGEKAAIKKMDMEASKQFLAELKVLTRVHHVNLVRLIGYCVEGSLFLVYEYVENGNLGQHLHGSGREPLPWTKRVQIALDSARGLEYIHEHTVPVYVHRDIKSANILIDQKFRAKVADFGLTKLTEVGGSATRGAMGTFGYMAPETVYGEVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFRGLVGVFEESFKETDKEEALRKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYIVVALSTLFSSTGNWDVGNFQNEDLVSLMSGR</sequence>
        <attributeList>
          <attribute name="crc64">CF5019DB428CFE1E</attribute>
          <attribute name="remark-internal">DIP protein A8R7E6 original sequence version: 79</attribute>
          <attribute name="no-uniprot-update"/>
          <attribute name="caution" nameAc="MI:0618">The protein could not be merged with EBI-12873142 because of some conflicts with the protein sequence (features which cannot be shifted).</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-9257-1">
        <names>
          <shortLabel>cerk1-mbp-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-59478E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15672627" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-9257-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9913">
                <names>
                  <shortLabel>bovin</shortLabel>
                  <fullName>Bos taurus (Bovine)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Bovine</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>