DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions in vitro In vitro tem transmission electron microscopy tem predetermined predetermined participant predetermined Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253038X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253037X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight by comassie molecular weight estimation by coomasie staining weight by comassie Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253032X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions ecolx Escherichia coli pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253033X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253035X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253031X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253036X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight by comassie molecular weight estimation by coomasie staining weight by comassie Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253030X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Functional architecture of the retromer cargo-recognition complex. Nature 2007 imex curation Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Hierro A., Rojas AL., Rojas R., Murthy N., Effantin G., Kajava AV., Steven AC., Bonifacino JS., Hurley JH. DIP original experiment: DIP-253034X Nature 2007 IMEx Functional architecture of the retromer cargo-recognition complex. vps29_human Vacuolar protein sorting-associated protein 29 Vesicle protein sorting 29 PEP11 homolog VPS29 DC7 DC15 MDS007 protein protein human Homo sapiens Human MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP DIP protein Q9UBQ0 original sequence version: 51 DIP protein Q9UBQ0-1 original sequence version: 117 DIP protein Q9UBQ0 original sequence version: 117 DIP protein Q9UBQ0 original sequence version: 129 6E0CDE6B720C9BF8 vps35_human Vacuolar protein sorting-associated protein 35 Vesicle protein sorting 35 Maternal-embryonic 3 VPS35 MEM3 TCCCTA00141 protein protein human Homo sapiens Human MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL DIP protein Q96QK1 original sequence version: 118 DIP protein Q96QK1 original sequence version: 44 DIP protein Q96QK1 original sequence version: 117 DIP protein Q96QK1 original sequence version: 127 28D2DD1C6B920A0A vp26a_human Vacuolar protein sorting-associated protein 26A VPS26A VPS26 Vesicle protein sorting 26A protein protein human Homo sapiens Human MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQASAEQPEM DIP protein O75436 original sequence version: 115 DIP protein O75436 original sequence version: 53 DIP protein O75436 original sequence version: 113 DIP protein O75436-1 original sequence version: 113 DIP protein O75436 original sequence version: 123 BD3B2EAA6CFCBFA9 vps29-vps35-10 8 11 unspecified role unspecified role unspecified role unspecified role Region 476-780 Region 476-780 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 10 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction vps29-vps26a-4 9 12 unspecified role unspecified role prey prey human Homo sapiens Human 11 unspecified role unspecified role prey prey human Homo sapiens Human 10 unspecified role unspecified role bait bait Q9UBQ0:p.Pro92Gly P92G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain P G This feature has been corrected as a result of our quality control procedures. The original label was 'P92G'. Wed May 02 19:20:56 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro92gly' Tue Jun 30 18:09:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro92Gly' Q9UBQ0:p.Trp93Asp W93D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain W D This feature has been corrected as a result of our quality control procedures. The original label was 'W93D'. Wed May 02 17:14:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp93asp' Tue Jun 30 17:18:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Trp93Asp' Q9UBQ0:p.Gly94Pro G94P mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain G P This feature has been corrected as a result of our quality control procedures. The original label was 'G94P'. Wed May 02 17:28:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly94pro' Tue Jun 30 19:11:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly94Pro' Q9UBQ0:p.Arg104Asp R104D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D This feature has been corrected as a result of our quality control procedures. The original label was 'R104D'. Wed May 02 17:09:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg104asp' Tue Jun 30 16:56:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg104Asp' Q9UBQ0:p.[Tyr139Ala;Ala141Asp;Leu142Asp] Y139A/A141D/L142D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L D certain certain sequence position certain certain certain sequence position certain A D certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y139A/A141D/L142D'. Wed May 02 16:42:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr139ala,ala141asp,leu142asp' Tue Jun 30 17:43:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr139Ala;Ala141Asp;Leu142Asp]' Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range Q9UBQ0:p.Pro92Ala P92A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain P A This feature has been corrected as a result of our quality control procedures. The original label was 'P92A'. Wed May 02 17:02:32 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro92ala' Tue Jun 30 19:41:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro92Ala' Q9UBQ0:p.Trp93Ala W93A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain W A This feature has been corrected as a result of our quality control procedures. The original label was 'W93A'. Wed May 02 15:50:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp93ala' Tue Jun 30 18:06:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Trp93Ala' human Homo sapiens Human association association vps35-vps29-10 2 10 unspecified role unspecified role prey prey human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q96QK1:p.[His769Ala;Asn772Ala;His776Ala] H769A/N772A/H776A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain H A certain certain sequence position certain certain certain sequence position certain N A certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H769A/N772A/H776A'. Wed May 02 14:42:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his769ala,asn772ala,his776ala' Tue Jun 30 19:37:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His769Ala;Asn772Ala;His776Ala]' Q96QK1:p.[Asn725Ala;Tyr729Ala] N725A/Y729A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain Y A certain certain sequence position certain certain certain sequence position certain N A This feature has been corrected as a result of our quality control procedures. The original label was 'N725A/Y729A'. Wed May 02 19:43:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn725ala,tyr729ala' Tue Jun 30 17:40:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asn725Ala;Tyr729Ala]' Q96QK1:p.[Thr672Asp;His675Asp] T672D/H675D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain H D certain certain sequence position certain certain certain sequence position certain T D This feature has been corrected as a result of our quality control procedures. The original label was 'T672D/H675D'. Wed May 02 15:53:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr672asp,his675asp' Tue Jun 30 18:42:29 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Thr672Asp;His675Asp]' Q96QK1:p.[Thr629Asp;Leu630Ala;Gly633Asp;Arg637Asp] T629D/L630A/G633D/R637D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D certain certain sequence position certain certain certain sequence position certain G D certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain T D This feature has been corrected as a result of our quality control procedures. The original label was 'T629D/L630A/G633D/R637D'. Wed May 02 18:10:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr629asp,leu630ala,gly633asp,arg637asp' Tue Jun 30 17:41:29 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Thr629Asp;Leu630Ala;Gly633Asp;Arg637Asp]' Q96QK1:p.[Leu579Asp;Arg582Asp;Gln586Ala;Leu589Asp] L579D/R582D/Q586A/Q589D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L D certain certain sequence position certain certain certain sequence position certain Q A certain certain sequence position certain certain certain sequence position certain R D certain certain sequence position certain certain certain sequence position certain L D Wed May 02 16:46:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu579asp,arg582asp,gln586ala,leu589asp' Tue Jun 30 16:57:42 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu579Asp;Arg582Asp;Gln586Ala;Leu589Asp]' Q96QK1:p.[Phe534Asp;Phe541Asp] F534D/F541D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D certain certain sequence position certain certain certain sequence position certain F D This feature has been corrected as a result of our quality control procedures. The original label was 'F534D/F541D'. Wed May 02 15:02:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe534asp,phe541asp' Tue Jun 30 18:33:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe534Asp;Phe541Asp]' human Homo sapiens Human physical association physical association vps35-vps26a-9 5 12 unspecified role unspecified role prey prey human Homo sapiens Human 10 unspecified role unspecified role prey prey human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human association association vps35-vps26a-10 4 12 unspecified role unspecified role prey prey Region 162-327 Region 162-327 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 11 unspecified role unspecified role bait bait Region 1-165 Region 1-165 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction vps26a-vps29-4 1 12 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 11 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 10 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association vps29-vps35-11 6 11 unspecified role unspecified role unspecified role unspecified role Region 476-780 Region 476-780 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 10 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction vps35-vps26a-11 7 12 unspecified role unspecified role prey prey human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q96QK1:p.[Phe534Asp;Phe541Asp] F534D/F541D mutation mutation certain certain sequence position certain certain certain sequence position certain F D certain certain sequence position certain certain certain sequence position certain F D This feature has been corrected as a result of our quality control procedures. The original label was 'F534D/F541D'. Wed May 02 15:30:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe534asp,phe541asp' Tue Jun 30 19:14:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe534Asp;Phe541Asp]' Q96QK1:p.[Leu579Asp;Arg582Asp;Gln586Ala;Leu589Asp] L579D/R582D/Q586A/Q589D mutation mutation certain certain sequence position certain certain certain sequence position certain L D certain certain sequence position certain certain certain sequence position certain Q A certain certain sequence position certain certain certain sequence position certain R D certain certain sequence position certain certain certain sequence position certain L D Wed May 02 18:19:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu579asp,arg582asp,gln586ala,leu589asp' Tue Jun 30 19:36:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu579Asp;Arg582Asp;Gln586Ala;Leu589Asp]' Q96QK1:p.[Thr629Asp;Leu630Ala;Gly633Asp;Arg637Asp] T629D/L630A/G633D/R637D mutation mutation certain certain sequence position certain certain certain sequence position certain R D certain certain sequence position certain certain certain sequence position certain G D certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain T D This feature has been corrected as a result of our quality control procedures. The original label was 'T629D/L630A/G633D/R637D'. Wed May 02 18:42:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr629asp,leu630ala,gly633asp,arg637asp' Tue Jun 30 18:35:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Thr629Asp;Leu630Ala;Gly633Asp;Arg637Asp]' Q96QK1:p.[Thr672Asp;His675Asp] T672D/H675D mutation mutation certain certain sequence position certain certain certain sequence position certain H D certain certain sequence position certain certain certain sequence position certain T D This feature has been corrected as a result of our quality control procedures. The original label was 'T672D/H675D'. Wed May 02 18:00:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr672asp,his675asp' Tue Jun 30 19:11:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Thr672Asp;His675Asp]' Q96QK1:p.[Asn725Ala;Tyr729Ala] N725A/Y729A mutation mutation certain certain sequence position certain certain certain sequence position certain Y A certain certain sequence position certain certain certain sequence position certain N A This feature has been corrected as a result of our quality control procedures. The original label was 'N725A/Y729A'. Wed May 02 16:15:06 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn725ala,tyr729ala' Tue Jun 30 18:38:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asn725Ala;Tyr729Ala]' Q96QK1:p.[His769Ala;Asn772Ala;His776Ala] H769A/N772A/H776A mutation mutation certain certain sequence position certain certain certain sequence position certain H A certain certain sequence position certain certain certain sequence position certain N A certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H769A/N772A/H776A'. Wed May 02 15:49:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his769ala,asn772ala,his776ala' Tue Jun 30 16:55:23 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His769Ala;Asn772Ala;His776Ala]' human Homo sapiens Human physical association physical association vps26a-vps29-5 3 12 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 11 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 10 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association