DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. DIP original experiment: DIP-261624X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink predetermined predetermined participant predetermined Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. DIP original experiment: DIP-261626X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. DIP original experiment: DIP-261623X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. DIP original experiment: DIP-261625X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Forwood JK., Thakur AS., Guncar G., Marfori M., Mouradov D., Meng W., Robinson J., Huber T., Kellie S., Martin JL., Hume DA., Kobe B. DIP original experiment: DIP-261622X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. q91v12-2 Cytosolic acyl coenzyme A thioester hydrolase Acot7 Bach Acyl-CoA thioesterase 7 Brain acyl-CoA hydrolase CTE-IIa Long chain acyl-CoA thioester hydrolase 43-kDa BACH mBACHa mBach protein protein mouse Mus musculus Mouse MSGPTTDTPAAIQICRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVHVMSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLERMETKWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASAFFTYVSLNQEGKPMPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP DIP protein Q91V12-2 original sequence version: 110 Major isoform. acot7-1 5 6 unspecified role unspecified role unspecified role unspecified role Region 16-161 Region 16-161 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction acot7-2 4 6 unspecified role unspecified role unspecified role unspecified role Region 160-338 Region 160-338 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction acot7-3 3 6 unspecified role unspecified role unspecified role unspecified role Region 16-161 Region 16-161 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Region 160-338 Region 160-338 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction acot7-4 2 6 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction acot7-5 1 6 unspecified role unspecified role unspecified role unspecified role Region 16-161 Region 16-161 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Region 160-338 Region 160-338 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction