DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Structure (London, England : 1993) 2006 imex curation Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. Only protein-protein interactions ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. DIP original experiment: DIP-66387X Structure (London, England : 1993) 2006 IMEx Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Structure (London, England : 1993) 2006 imex curation Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. DIP original experiment: DIP-66389X Structure (London, England : 1993) 2006 IMEx Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. Structure (London, England : 1993) 2006 imex curation Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Kuwasako K., He F., Inoue M., Tanaka A., Sugano S., Güntert P., Muto Y., Yokoyama S. DIP original experiment: DIP-66388X Structure (London, England : 1993) 2006 IMEx Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP. sf3a1_human Splicing factor 3A subunit 1 Spliceosome-associated protein 114 SF3a120 SF3A1 SAP114 protein protein human Homo sapiens Human MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLALKERGGRKK DIP protein Q15459 original sequence version: 66 DIP protein Q15459 original sequence version: 158 7259F1EC4577305C sf3a3_human Splicing factor 3A subunit 3 Spliceosome-associated protein 61 SF3a60 SF3A3 SAP61 protein protein human Homo sapiens Human METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNAEYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSLFAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL DIP protein Q12874 original sequence version: 67 6E6F6EA17777E1E2 sf3a1-sf3a3-1 1 4 unspecified role unspecified role unspecified role unspecified role Region 134-217 Region 134-217 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role Region 71-107 Region 71-107 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction sf3a1-sf3a3-2 3 4 unspecified role unspecified role bait bait Region 134-217 Region 134-217 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q15459:p.Leu169Lys L169K mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L K This feature has been corrected as a result of our quality control procedures. The original label was 'L169K'. Wed May 02 15:48:38 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu169lys' Tue Jun 30 17:01:37 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu169Lys' GST-Tag GST-Tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 5 unspecified role unspecified role prey prey Region 71-107 Region 71-107 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain His-Tag His-Tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli direct interaction direct interaction sf3a1-sf3a3-3 2 4 unspecified role unspecified role bait bait Region 48-110 Region 48-110 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q15459:p.Lys55Leu K55L mutation increasing mutation increasing interaction mutation increasing certain certain sequence position certain certain certain sequence position certain K L This feature has been corrected as a result of our quality control procedures. The original label was 'K55L'. Wed May 02 14:43:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys55leu' Tue Jun 30 17:44:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys55Leu' GST-Tag GST-Tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 5 unspecified role unspecified role prey prey Region 71-107 Region 71-107 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain His-Tag His-Tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli direct interaction direct interaction