DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure (London, England : 1993) 2006 imex curation Nezami AG., Poy F., Eck MJ. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Nezami AG., Poy F., Eck MJ. DIP original experiment: DIP-66140X Structure (London, England : 1993) 2006 IMEx Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure (London, England : 1993) 2006 imex curation Nezami AG., Poy F., Eck MJ. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Nezami AG., Poy F., Eck MJ. DIP original experiment: DIP-66137X Structure (London, England : 1993) 2006 IMEx Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure (London, England : 1993) 2006 imex curation Nezami AG., Poy F., Eck MJ. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Nezami AG., Poy F., Eck MJ. DIP original experiment: DIP-66138X Structure (London, England : 1993) 2006 IMEx Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure (London, England : 1993) 2006 imex curation Nezami AG., Poy F., Eck MJ. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Nezami AG., Poy F., Eck MJ. DIP original experiment: DIP-66141X Structure (London, England : 1993) 2006 IMEx Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure of the autoinhibitory switch in formin mDia1. Structure (London, England : 1993) 2006 imex curation Nezami AG., Poy F., Eck MJ. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Nezami AG., Poy F., Eck MJ. DIP original experiment: DIP-66139X Structure (London, England : 1993) 2006 IMEx Structure of the autoinhibitory switch in formin mDia1. diap1_mouse Protein diaphanous homolog 1 Diaphanous-related formin-1 p140mDIA Diaph1 Diap1 protein protein mouse Mus musculus Mouse MEPSGGGLGPGRGTRDKKKGRSPDELPATGGDGGKHKKFLERFTSMRIKKEKEKPNSAHRNSSASYGDDPTAQSLQDISDEQVLVLFEQMLVDMNLNEEKQQPLREKDIVIKREMVSQYLHTSKAGMNQKESSRSAMMYIQELRSGLRDMHLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETSGNYDSRNQHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENEDMKVQLCVFDEQGDEDFFDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECVSQIVLHKNGTDPDFKCRHLQIDIERLVDQMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMKKMENDFEQKLQDLQGEKDALDSEKQQITAQKQDLEAEVSKLTGEVAKLSKELEDAKNEMASLSAVVVAPSVSSSAAVPPAPPLPGDSGTVIPPPPPPPPLPGGVVPPSPPLPPGTCIPPPPPLPGGACIPPPPQLPGSAAIPPPPPLPGVASIPPPPPLPGATAIPPPPPLPGATAIPPPPPLPGGTGIPPPPPPLPGSVGVPPPPPLPGGPGLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGVPAAPVLPFGLTPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNELFAKLTLAFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKEEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQKMTLLHFLAELCENDHPEVLKFPDELAHVEKASRVSAENLQKSLDQMKKQIADVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQVNRKAGCAVTSLLASELTKDDAMAPGPVKVPKKSEGVPTILEEAKELVGRAS DIP protein O08808 original sequence version: 62 DIP protein O08808 original sequence version: 141 09404164873CA7C1 diaph1-diaph1-2 4 6 unspecified role unspecified role unspecified role unspecified role FH2-DAD Region 736-1200 FH2-DAD Region 736-1200 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role 2-369 2-369 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction diaph1-diaph1-4 1 6 unspecified role unspecified role unspecified role unspecified role FH2-DAD Region 736-1200 FH2-DAD Region 736-1200 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role DID Region 131-369 DID Region 131-369 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction diaph1-diaph1-6 2 6 unspecified role unspecified role unspecified role unspecified role DAD Region 1175-1200 DAD Region 1175-1200 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role DID Region 131-369 DID Region 131-369 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction diaph1-diaph1-8 3 6 unspecified role unspecified role unspecified role unspecified role DAD Region 1175-1200 DAD Region 1175-1200 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role DID Region 131-369 DID Region 131-369 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction diaph1-diaph1-10 5 6 unspecified role unspecified role unspecified role unspecified role DAD Region 1175-1200 DAD Region 1175-1200 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role GBD-DID Region 72-369 GBD-DID Region 72-369 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction