<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
      </bibref>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Activation of NLRP3 and AIM2 Inflammasomes in Kupffer Cells in Hepatic Ischemia/Reperfusion.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="25327779" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9844927" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Activation of NLRP3 and AIM2 Inflammasomes in Kupffer Cells in Hepatic Ischemia/Reperfusion.</attribute>
            <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2014</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Kim H.Y., Kim S.J., Lee S.M.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">sunmee@skku.edu</attribute>
            <attribute name="author-announcement">05-Jan-2015: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="25327779" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="10090">
            <names>
              <shortLabel>mouse-liver</shortLabel>
              <fullName>Mus musculus</fullName>
            </names>
            <tissue>
              <names>
                <shortLabel>liver</shortLabel>
                <fullName>liver</fullName>
              </names>
              <xref>
                <primaryRef db="intact" dbAc="MI:0469" id="IA:0195" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="brenda" dbAc="MI:0864" id="BTO:0000759" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1347779" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-300796" refType="identity" refTypeAc="MI:0356"/>
              </xref>
            </tissue>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="contact-email" nameAc="MI:0634">sunmee@skku.edu</attribute>
          <attribute name="accepted">Accepted 2014-OCT-13 by LUANA</attribute>
          <attribute name="publication year" nameAc="MI:0886">2014</attribute>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>casp1_mouse</shortLabel>
          <fullName>Caspase-1</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Interleukin-1 beta convertase</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Interleukin-1 beta-converting enzyme</alias>
          <alias type="gene name synonym" typeAc="MI:0302">p45</alias>
          <alias type="gene name" typeAc="MI:0301">Casp1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Il1bc</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P29452" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000027015" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-489700" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_033937.2"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032730" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033198" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046010" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050700" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051882" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060081" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070269" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071310" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072557" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072558" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072559" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097169" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097179" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097194" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097199" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097300" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140447" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140448" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901998" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903265" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001309" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001315" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002138" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015917" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016129" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029030" version="SP_202"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033139" version="SP_202"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-168638" version="SP_202"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-448706" version="SP_202"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5620971" version="SP_202"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000025888" version="SP_202" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000027015" version="SP_202" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001774" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001819" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004175" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007520" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007613" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008233" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009617" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010506" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0014070" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016485" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016540" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019900" version="SP_202"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" version="SP_202"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34659N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MADKILRAKRKQFINSVSIGTINGLLDELLEKRVLNQEEMDKIKLANITAMDKARDLCDHVSKKGPQASQIFITYICNEDCYLAGILELQSAPSAETFVATEDSKGGHPSSSETKEEQNKEDGTFPGLTGTLKFCPLEKAQKLWKENPSEIYPIMNTTTRTRLALIICNTEFQHLSPRVGAQVDLREMKLLLEDLGYTVKVKENLTALEMVKEVKEFAACPEHKTSDSTFLVFMSHGIQEGICGTTYSNEVSDILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVRDSEEDFLTDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPEFRLQMPTADRVTLTKRFYLFPGH</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P29452 original sequence version: 87</attribute>
          <attribute name="remark-internal">DIP protein P29452 original sequence version: 158</attribute>
          <attribute name="remark-internal">DIP protein P29452 original sequence version: 123</attribute>
          <attribute name="remark-internal">DIP protein P29452 original sequence version: 122</attribute>
          <attribute name="crc64">3BEBCEFA67C69B03</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>panx1_mouse</shortLabel>
          <fullName>Pannexin-1</fullName>
          <alias type="gene name" typeAc="MI:0301">Panx1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9JIP4" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000126405" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5RL18" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9CXS7" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6272917" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000031934" version="SP_147" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000164273" version="SP_147" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001819" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003779" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005198" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005243" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006812" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007267" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015267" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0022829" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0022840" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032059" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032730" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033198" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051015" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055085" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" version="SP_147"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000990" version="SP_147"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039099" version="SP_147"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q9JIP4" version="SP_147"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-112303" version="SP_147"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-844456" version="SP_147"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005921" version="SP_147"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_062355.2"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MAIAHLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKSSLQSESGNLPLWLHKFFPYILLLFAILLYLPALFWRFSAAPHLCSDLKFIMEELDKVYNRAIKAAKSARDLDLRDGPGPPGVTENVGQSLWEISESHFKYPIVEQYLKTKKNSSHLIMKYISCRLVTFVVILLACIYLSYYFSLSSLSDEFLCSIKSGVLKNDSTIPDRFQCKLIAVGIFQLLSLINLIVYALLIPVVVYTFFIPFRQKTDILKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISELKSYKCLKVLENIKSNGQGIDPMLLLTNLGMIKMDIIDGKIPTSLQTKGEDQGSQRVEFKDLDLSSEAAANNGEKNSRQRLLNPSC</sequence>
        <attributeList>
          <attribute name="crc64">86AF6167C5D39565</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>asc_mouse</shortLabel>
          <fullName>Apoptosis-associated speck-like protein containing a CARD</fullName>
          <alias type="gene name" typeAc="MI:0301">Pycard</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Asc</alias>
          <alias type="gene name synonym" typeAc="MI:0302">PYD and CARD domain-containing protein</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9EPB4" version="SP_102" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000033056" version="SP_183" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9D2W9" version="SP_102" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6253348" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000030793" version="SP_183" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000033056" version="SP_183" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001773" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002230" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002277" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002588" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002821" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005138" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005523" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008385" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009617" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010506" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010803" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016505" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017024" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030838" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031647" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032088" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032090" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032688" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042104" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042771" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042981" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043087" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043124" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043281" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044351" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046983" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050766" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050870" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051260" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061702" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070700" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071347" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071356" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071901" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072332" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072558" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072559" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090200" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097153" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097169" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097202" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900016" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000406" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001056" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001238" version="SP_183"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001242" version="SP_183"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001315" version="SP_183"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_183"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004020" version="SP_183"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_183"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033516" version="SP_183"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N1F" version="SP_183"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_075747.3"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-27619N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQMDAIDLTDKLVSYYLESYGLELTMTVLRDMGLQELAEQLQTTKEESGAVAAAASVPAQSTARTGHFVDQHRQALIARVTEVDGVLDALHGSVLTEGQYQAVRAETTSQDKMRKLFSFVPSWNLTCKDSLLQALKEIHPYLVMDLEQS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q9EPB4 original sequence version: 106</attribute>
          <attribute name="remark-internal">DIP protein Q9EPB4 original sequence version: 104</attribute>
          <attribute name="remark-internal">DIP protein Q9EPB4 original sequence version: 103</attribute>
          <attribute name="crc64">2A4EA40194870B31</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>aim2_mouse</shortLabel>
          <fullName>Interferon-inducible protein AIM2</fullName>
          <alias type="gene name" typeAc="MI:0301">Aim2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Gm1313</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ifi210</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Interferon-inducible protein 210</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Interferon-inducible protein p210</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q91VJ1" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000119465" version="SP_131" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000132253" version="SP_131" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6253384" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000037860" version="SP_131" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000147604" version="SP_131" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000166137" version="SP_131" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032088" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035458" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035690" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044546" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002230" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070269" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097169" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1904270" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001056" version="SP_131"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004020" version="SP_131"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004021" version="SP_131"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_131"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040205" version="SP_131"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N00" version="SP_131"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JBM" version="SP_131"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-844615" version="SP_131"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" version="SP_131"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237133.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237137.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237144.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006496982.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006496989.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001013801.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176969.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176971.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176972.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176975.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176976.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176977.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176981.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176983.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176985.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176987.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176990.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176994.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176996.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176999.1"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MESEYREMLLLTGLDHITEEELKRFKYFALTEFQIARSTLDVADRTELADHLIQSAGAASAVTKAINIFQKLNYMHIANALEEKKKEAERKLMTNTKKRGTQKVENRSQAENCSAASATRSDNDFKEQAATEVCPQAKPQKKQMVAEQEAIREDLQKDPLVVTVLKAINPFECETQEGRQEIFHATVATETDFFFVKVLNAQFKDKFIPKRTIKISNYLWHSNFMEVTSSSVVVDVESNHEVPNNVVKRARETPRISKLKIQPCGTIVNGLFKVQKITEEKDRVLYGIHDKTGTMEVLVLGNPSKTKCEEGDKIRLTFFEVSKNGVKIQLKSGPCSFFKVIKAAKPKTDMKSVE</sequence>
        <attributeList>
          <attribute name="crc64">E860C5D902AA5D35</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-23404-1">
        <names>
          <shortLabel>panx1-casp1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844945" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">asc</alias>
            </names>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="8">
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="9">
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>association</shortLabel>
            <fullName>association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">f2a</attribute>
          <attribute name="comment" nameAc="MI:0612">Anti-Panx1 immunoprecipitated ASC and the p10 subunit of caspase-1 (Fig. 2A).</attribute>
        </attributeList>
      </interaction>
      <interaction id="10" imexId="IM-23404-2">
        <names>
          <shortLabel>pycard-aim2-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844951" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <interactorRef>5</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="12">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">asc</alias>
            </names>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">f3c</attribute>
          <attribute name="comment" nameAc="MI:0612">Anti-Panx1 immunoprecipitated ASC and the p10 subunit of caspase-1 (Fig. 2A).</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>